Journal of Nephrology最新文献

{"title":"Unexpected finding of AA amyloidosis with novel genetic variants in the MEFV gene in patients undergoing kidney biopsy for proteinuria. A case series.","authors":"Beyza Doğan, Süleyman Karaköse, Edip Erkuş, İbrahim Güney","doi":"10.1093/joneph/aajag107","DOIUrl":"10.1093/joneph/aajag107","url":null,"abstract":"<p><p>Amyloidosis is a systemic clinical condition characterised by the extracellular deposition of misfolded proteins in various organs, most frequently involving the heart, kidneys, gastrointestinal tract, and bone marrow. Among its types, AA amyloidosis accounts for approximately 15% of cases and is mainly secondary to chronic infectious or inflammatory conditions. The association between Familial Mediterranean Fever (FMF) and AA amyloidosis is well-established, with the MEFV gene's M694V mutation being the most recognised risk factor. However, the role of other genetic variants often remains underestimated. This case series presents a spectrum of AA amyloidosis patients harbouring various MEFV gene variants. By emphasizing the clinical presentations and diagnostic challenges encountered, this report aims to highlight the clinical significance of heterozygous and less common variants that are frequently overlooked in the progression to AA amyloidosis.</p>","PeriodicalId":16542,"journal":{"name":"Journal of Nephrology","volume":" ","pages":"1518-1521"},"PeriodicalIF":2.6,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148969006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal steatosis in the tubulointerstitial compartment in primary glomerulopathies: biopsy evidence and correlation with disease severity.","authors":"Gorkem Celebi, Ozan Sakir, Meral Uner, Arzu Saglam, Rahmi Yilmaz, Hasan Yeter","doi":"10.1093/joneph/aajag139","DOIUrl":"10.1093/joneph/aajag139","url":null,"abstract":"<p><strong>Background: </strong>While dyslipidemia is a well-established systemic risk factor in glomerular diseases, the clinical and histopathological relevance of compartmental intrarenal lipid deposition in primary glomerulonephritis (GN) remains insufficiently elucidated. Recent evidence suggests that lipid accumulation may directly contribute to glomerular and tubulointerstitial injury via pro-inflammatory and oxidative mechanisms.</p><p><strong>Methods: </strong>In this single-center, cross-sectional analysis, we examined 31 adult patients with biopsy-proven primary GN-IgA nephropathy (IgAN), membranous nephropathy (MN), and focal segmental glomerulosclerosis/minimal change disease (FSGS/MCD)-diagnoses. Renal tissue specimens were subjected to Oil Red O staining to quantify lipid accumulation within tubular, interstitial, and vascular compartments. Clinical parameters and laboratory indices were assessed. Histopathologic correlations were performed using Oxford MEST-C classification (for IgAN) and Interstitial Fibrosis and Tubular Atrophy (IFTA) scoring.</p><p><strong>Results: </strong>Intrarenal lipid deposition was prevalent across compartments: tubular (84%), interstitial (74%), and vascular (61%). In IgAN patients, both the extent and morphology of tubular steatosis were strongly correlated with composite MEST-C scores (P < .01). In MN, tubular lipid burden was significantly associated with systolic blood pressure and proteinuria levels (P < .01). Notably, interstitial and vascular lipid accumulation demonstrated positive associations independent of systemic lipid levels. In FSGS/MCD cases, tubular steatosis correlated with both low density lipoprotein (LDL) and interstitial lipid scores (P < .01), whereas vascular lipid presence was linked to the degree of proteinuria (P < .05).</p><p><strong>Conclusions: </strong>Intrarenal lipid deposition is a prevalent histological finding in primary GN and correlates with both structural injury and clinical disease burden. These findings support the hypothesis that local lipid accumulation may represent a pathophysiologically relevant biomarker of disease activity.</p>","PeriodicalId":16542,"journal":{"name":"Journal of Nephrology","volume":" ","pages":"1470-1478"},"PeriodicalIF":2.6,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148604071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumoral calcinosis in kidney failure.","authors":"Arthur Gus Manfro, Vanderlei Carlos Bertuol Junior, Roberto Ceratti Manfro","doi":"10.1093/joneph/aajag104","DOIUrl":"10.1093/joneph/aajag104","url":null,"abstract":"","PeriodicalId":16542,"journal":{"name":"Journal of Nephrology","volume":" ","pages":"1524-1525"},"PeriodicalIF":2.6,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148258475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of recombinant human growth hormone treatment in children with growth disorders secondary to nephrotic syndrome.","authors":"Fazhan Zhong, Xiaowei Fan, Miao Zhang, Huabin Yang, Huiying Deng, Yan Gao, Peiqing Li, Xia Gao","doi":"10.1093/joneph/aajag098","DOIUrl":"10.1093/joneph/aajag098","url":null,"abstract":"<p><strong>Background: </strong>Patients with nephrotic syndrome (NS) treated with glucocorticoids often suffer from growth disorders. This study aimed to explore the impact of recombinant human growth hormone treatment in children with growth disorders secondary to NS.</p><p><strong>Methods: </strong>This retrospective study enrolled patients with NS treated at Guangzhou Women and Children's Medical Center between May 2015 and November 2023. Patients were divided into the recombinant human growth hormone group and the conventional group. The primary outcome was height increment. Secondary outcomes included height standard deviation score, predicted adult height standard deviation score, and height velocity.</p><p><strong>Results: </strong>Among 129 enrolled children (89 in the recombinant human growth hormone group, 40 in the conventional group), the recombinant human growth hormone group showed significantly greater height increments at 6 months (4.80 ± 1.42 vs. 2.02 ± 0.91 cm), 12 months (9.07 ± 2.46 vs. 4.39 ± 1.73 cm), and 24 months (15.34 ± 5.20 vs. 7.88 ± 3.43 cm; all P < .001). Similarly, height standard deviation score and predicted adult height standard deviation score improvements were significantly greater in the recombinant human growth hormone group at all time points (all P < .001). Height velocity was also higher in the recombinant human growth hormone group at 6 and 12 months (both P < .001). These associations remained significant after multivariate adjustment. No significant differences in glucocorticoid exposure during follow-up were observed between groups. Multivariate analysis at 12 months indicated that cumulative glucocorticoid dosage was negatively associated with height standard deviation score (β=-.0022, 95% CI: -0.0041, -0.0004; P = .020) and predicted adult height (β=-.0148, 95% CI: -0.0288, -0.0008; P = .038).</p><p><strong>Conclusion: </strong>The results suggested that recombinant human growth hormone treatment in children with NS significantly improved height, height standard deviation score, predicted adult height standard deviation score, and height velocities, compared with conventional treatment.</p>","PeriodicalId":16542,"journal":{"name":"Journal of Nephrology","volume":" ","pages":"1382-1389"},"PeriodicalIF":2.6,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148977173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crescents in native kidney biopsies from patients with IgA nephropathy and the risk of recurrence after kidney transplantation: a retrospective cohort study, systematic literature review and meta-analysis of observational studies.","authors":"Gabriella Guzzo, Muaamar Al-Gobari, Cécile Jaques, Daniel Teta, Manuel Pascual, Francisco Herrera-Gomez","doi":"10.1093/joneph/aajag169","DOIUrl":"10.1093/joneph/aajag169","url":null,"abstract":"<p><strong>Background: </strong>IgA nephropathy (IgAN) is associated with a high risk of kidney failure. Whenever this occurs, the best treatment option is kidney transplantation. IgAN recurrence in the kidney allograft may increase the risk of allograft loss. The association of glomerular crescents in native IgAN is a negative prognostic factor for the progression to kidney failure. The aim of our study was to clarify whether the presence of crescents in native kidney biopsies represents a risk factor for IgAN recurrence in renal allografts.</p><p><strong>Methods: </strong>The association between glomerular crescents in native kidney biopsies and IgAN recurrence was investigated in IgAN patients who underwent kidney transplantation at Lausanne University Hospital from 2003 to 2019. A systematic literature review was performed in MEDLINE, Embase, Cochrane CENTRAL, Web of Science and PMC from inception to November 2025, excluding reviews. Aggregate data were analyzed in a meta-analysis. The overall Risk Ratio (RR) with their corresponding 95% confidence interval (95% CI) was obtained via the Hartung-Knapp-Sidik-Jonkman adjustment method, after verifying heterogeneity (I2). Reporting bias was visualized in a funnel plot using STATA.</p><p><strong>Results: </strong>The Lausanne cohort included 63 patients with IgAN who underwent kidney transplantation. We found no association between glomerular crescents in native kidney biopsies and IgA recurrence in the renal allograft. Five additional cohorts were included in our meta-analysis, ultimately merging data from 311 patients, of whom 23% with recurrent IgAN. Crescent prevalence ranged from 12 to 62%, confirming the absence of association with an increased risk of IgAN recurrence [RR 1.53 (95% CI: 0.40-5.90), P = .41].</p><p><strong>Conclusions: </strong>Glomerular crescents, especially when present in more than 25% of viable glomeruli, remain an unfavorable prognostic factor for the progression of IgAN to kidney failure; however, they may not represent a risk factor for disease recurrence in renal allografts.</p>","PeriodicalId":16542,"journal":{"name":"Journal of Nephrology","volume":" ","pages":"1363-1372"},"PeriodicalIF":2.6,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between sarcopenia and inflammation in non-geriatric patients with chronic kidney disease: a comparison of hemodialysis and non-hemodialysis patients.","authors":"Mert Aric, Emine Meltem, Zahide Adiyaman, Selma Alagoz","doi":"10.1093/joneph/aajag120","DOIUrl":"10.1093/joneph/aajag120","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia is an increasingly recognized complication of chronic kidney disease (CKD), contributing to impaired physical function and higher mortality. While most evidence derives from elderly populations, its frequency and inflammatory correlates in younger adults remain underexplored. This study aimed to investigate the prevalence of sarcopenia and its association with inflammatory markers in a non-geriatric CKD cohort, including both hemodialysis and non-dialysis patients.</p><p><strong>Methods: </strong>This cross-sectional observational study included 128 non-geriatric CKD patients (18-65 years), 60 of whom were on maintenance hemodialysis. Sarcopenia was diagnosed according to EWGSOP2 criteria using handgrip strength, bioelectrical impedance analysis, and 4-meter gait-speed testing. Serum interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) were measured by ELISA, while C-reactive protein (CRP) served as another inflammatory marker. SPSS v27.0 was used for statistical analysis.</p><p><strong>Results: </strong>Sarcopenia was confirmed in 21.9% of the cohort, with a significantly higher prevalence among hemodialysis patients (31.7% vs 13.2%, P < .05). The prevalence of sarcopenia increased progressively with advancing CKD stage in the overall cohort (P < .05). Dialysis status was the most consistent independent predictor of sarcopenia (fully adjusted OR = 8.28, P = .004). IL-6 ≥ 110 ng/L and TNF-α > 150 ng/L were associated with higher sarcopenia prevalence and lower appendicular skeletal muscle mass, respectively (P < .05).</p><p><strong>Conclusion: </strong>Sarcopenia is highly prevalent among non-geriatric CKD patients and increases with disease progression. Dialysis remains the strongest independent predictor, while elevated IL-6 and TNF-α levels reflect inflammation-related muscle loss.</p>","PeriodicalId":16542,"journal":{"name":"Journal of Nephrology","volume":" ","pages":"1401-1410"},"PeriodicalIF":2.6,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148712462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High temperature-attributable chronic kidney disease burden in China, 1990-2023: temporal trends, population aging as the dominant driver, and projections to 2036.","authors":"Shuai Wang, Lihong Chi, Yanping Wang, Hailing Luo, Xingye Zhou","doi":"10.1093/joneph/aajag263","DOIUrl":"https://doi.org/10.1093/joneph/aajag263","url":null,"abstract":"<p><strong>Background: </strong>Ambient temperatures have risen in China over recent decades, but the long-term disease burden of chronic kidney disease (CKD) estimated to be attributable to high temperature has not been systematically quantified. We aimed to estimate this burden from 1990 to 2023 and project trends to 2036.</p><p><strong>Methods: </strong>Using Global Burden of Disease Study 2023 data, we extracted deaths, DALYs, age-standardized mortality rate (ASMR), and age-standardized DALY rate (ASDR) for high temperature-attributable CKD in China. Joinpoint regression and estimated annual percentage change (EAPC) analyses assessed temporal trends. Decomposition analysis identified drivers of DALY changes. Bayesian age-period-cohort models projected the burden to 2036.</p><p><strong>Results: </strong>From 1990 to 2023, ASMR increased from 0.04 to 0.08 per 100,000, and ASDR rose from 1.42 to 1.57 per 100,000. Joinpoint regression revealed an accelerating trend (APC: 0.17% for ASDR, 1.63% for ASMR). EAPC analysis showed divergent sex-specific trends. Population aging was the primary driver of DALY increases, with other factors having offsetting effects. By 2036, total deaths are projected to reach 1,261 (95% CrI: 800-1,986), a 17.1% increase from 2023.</p><p><strong>Conclusion: </strong>The burden of high temperature-attributable CKD in China has increased over three decades and is projected to continue rising. Elderly males are the most vulnerable group, and targeted interventions are urgently needed.</p>","PeriodicalId":16542,"journal":{"name":"Journal of Nephrology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149238650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes, stone composition, and renal function in a large cohort of patients with nephrolithiasis.","authors":"Omri Besor, Michal Cohen, Shuruk Nasser, Ateret Malachi, Ariela Fremder, Ori Liran, Yaniv Shilo","doi":"10.1093/joneph/aajag260","DOIUrl":"https://doi.org/10.1093/joneph/aajag260","url":null,"abstract":"<p><strong>Background: </strong>Nephrolithiasis is linked to chronic kidney disease (CKD), and diabetic patients may be at higher risk for renal decline. However, the interaction of diabetes, stone composition, and estimated glomerular filtration rate (eGFR) trajectory in patients with nephrolithiasis remains underexplored, particularly in community-based populations.</p><p><strong>Methods: </strong>In this retrospective cohort study of adult stone formers with a urinary stone composition analysis on file, diabetes status and stone composition were extracted from electronic records of a large health maintenance organization. Longitudinal eGFR measurements assessed renal function decline, and the effects of stone type, diabetes, and recurrent stone events on eGFR trajectory were evaluated.</p><p><strong>Results: </strong>This study included 6,771 stone formers; 1,543 (23%) had diabetes. Diabetic patients had a significantly higher prevalence of uric-acid stones (18.3% vs. 6.5%, p<0.0001). Baseline eGFR differed robustly by stone type and diabetes status. After adjustment for age, sex, BMI, and hypertension, the rate of eGFR decline did not differ significantly by diabetes status within either the calcium-oxalate nor uric-acid subtype. Recurrent stone formers had greater renal function loss, while socioeconomic status had limited impact on eGFR change.</p><p><strong>Conclusion: </strong>Diabetic and non-diabetic stone formers show distinct baseline eGFR profiles that differ by stone composition, and diabetes was strongly associated with uric-acid stone formation; however, diabetes was not associated with an accelerated rate of eGFR decline once adjusted for age, sex, BMI, and hypertension. These findings support baseline risk stratification, rather than an accelerated-decline phenotype, as the key actionable insight for diabetic stone formers.</p>","PeriodicalId":16542,"journal":{"name":"Journal of Nephrology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149238695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of a central venous catheter as vascular access at the start of a regular hemodialysis program: impact on mortality over 2 years.","authors":"Angélica Peçanha da Silva, Fabiana B Nerbass, Helbert do Nascimento Lima, Ricardo C Sesso, Jocemir R Lugon","doi":"10.1093/joneph/aajag259","DOIUrl":"https://doi.org/10.1093/joneph/aajag259","url":null,"abstract":"<p><strong>Background: </strong>The recommended access for starting chronic hemodialysis (HD) is an arteriovenous fistula (AVF), but a (CVC) continues to be frequently used. Worldwide, its use has been associated with higher mortality, but data from Brazil are lacking.</p><p><strong>Methods: </strong>Analytical, observational, and retrospective cohort study that aimed at analyzing the data available in the Brazilian Monthly Dialysis Registry database from Jan/2011 to Dec/2023. Using data from this registry, we evaluated the frequency of CVC use (regardless of whether tunneled or non-tunneled) at the start of HD across 13 years and assessed its impact on all-cause mortality over 2 years.</p><p><strong>Results: </strong>We studied 10,182 patients. The mean age was 59 (47-69) years; 59% were male, and 33% had diabetes. CVC use at HD entry increased substantially in the last 10 years. The 2-year mortality rates for CVC and primary AVF/graft users were 20% and 9%, respectively, P < 0.001. In the fully adjusted multivariate model, the use of CVC persisted significantly associated with mortality (HR 1.69, 95%CI 1.23-2.25, P=0.001). Other variables directly associated with mortality were age (HR 1.04, 95%CI 1.03-1.05, P=0.001), and serum ferritin (HR 1.18, 95%CI 1.06-1.30, P=0.002). Serum albumin (HR 0.86, 95%CI 0.84-0.88, P<0.001) and URR (HR 0.97, 95%CI 0.96-0.97, P<0.001) emerged as protective factors.</p><p><strong>Conclusions: </strong>CVC use was associated with a 1.69-fold increased risk of 2-year mortality. The increasing use of CVCs in Brazil is concerning and highlights the need for public health strategies promoting timely permanent vascular access before HD initiation.</p>","PeriodicalId":16542,"journal":{"name":"Journal of Nephrology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149238707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute kidney injury in pregnancy is associated with increased risks for adverse maternal and neonatal outcomes: an integrated health system study.","authors":"Mehdi Kashani, Darah Dilmaghani, Regan N Theiler, Yan Li, Deondre Jordan, Danette Bruns, Farbod Yousefi, Vesna D Garovic, Kianoush B Kashani","doi":"10.1093/joneph/aajag125","DOIUrl":"https://doi.org/10.1093/joneph/aajag125","url":null,"abstract":"<p><strong>Background: </strong>Pregnancy-related acute kidney injury (PrAKI) is an uncommon but serious complication associated with adverse maternal and neonatal outcomes, with limited data in high-resource settings.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study of 29 586 deliveries at Mayo Clinic hospitals between 2017 and 2022. PrAKI was defined using Kidney Disease Improving Global Outcomes (KDIGO) creatinine criteria. Maternal characteristics, nephrotoxin exposure, clinical interventions, and neonatal outcomes were compared between patients with and without PrAKI.</p><p><strong>Results: </strong>PrAKI occurred in 341 patients (1.15%). Compared with controls, PrAKI was associated with higher rates of chronic hypertension (28.7% vs 5.2%), cesarean delivery (68.5% vs 35.1%), intensive care unit (ICU) admission (59.1% vs 6.2%), and nephrotoxin exposure (58.7% vs 31.6%) (all P < .0001). Dialysis was required in 7.1% of patients with PrAKI, with 1.17% remaining dependent at discharge and 0.88% at 30 and 90 days; no control patients required dialysis. Neonates of mothers with PrAKI had higher rates of prematurity and neonatal ICU (NICU) admission (48.7% vs 9.8%; P < .0001). Maternal mortality was rare.</p><p><strong>Conclusions: </strong>PrAKI is a marker of severe maternal illness and is associated with adverse maternal and neonatal outcomes. Although most patients recover kidney function, a subset develop persistent dysfunction. Early identification, cautious use of nephrotoxic medications, and structured postpartum follow-up are essential.</p>","PeriodicalId":16542,"journal":{"name":"Journal of Nephrology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149194597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}