{"title":"Corrigendum: Presentation Abstracts of the North American Skull Base Society.","authors":"","doi":"10.1055/s-0045-1811603","DOIUrl":"10.1055/s-0045-1811603","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1055/s-015-61030.][This corrects the article DOI: 10.1055/s-0045-1803264.].</p>","PeriodicalId":16513,"journal":{"name":"Journal of Neurological Surgery Part B: Skull Base","volume":"86 Suppl 1","pages":"e3"},"PeriodicalIF":0.9,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12396895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum: Presentation Abstracts of the North American Skull Base Society.","authors":"","doi":"10.1055/s-0045-1809309","DOIUrl":"https://doi.org/10.1055/s-0045-1809309","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1055/s-015-61030.][This corrects the article DOI: 10.1055/s-0045-1803753.][This corrects the article DOI: 10.1055/s-0045-1803827.].</p>","PeriodicalId":16513,"journal":{"name":"Journal of Neurological Surgery Part B: Skull Base","volume":"86 Suppl 1","pages":"e1"},"PeriodicalIF":0.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum: Presentation Abstract of the North American Skull Base Society.","authors":"","doi":"10.1055/s-0045-1806731","DOIUrl":"https://doi.org/10.1055/s-0045-1806731","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1055/s-015-61030.][This corrects the article DOI: 10.1055/s-0045-1803328.][This corrects the article DOI: 10.1055/s-0045-1803567.][This corrects the article DOI: 10.1055/s-0045-1803688.][This corrects the article DOI: 10.1055/s-0045-1803219.][This corrects the article DOI: 10.1055/s-0045-1803252.].</p>","PeriodicalId":16513,"journal":{"name":"Journal of Neurological Surgery Part B: Skull Base","volume":"86 Suppl 1","pages":"e2"},"PeriodicalIF":0.9,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11945205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David A Gudis, Benjamin S Bleier, Jean Anderson Eloy, James J Evans, Juan Carlos Fernandez-Miranda, Paul A Gardner, Mathew Geltzeiler, Jessica W Grayson, Richard J Harvey, Elisa A Illing, David W Kennedy, Cristine Klatt-Cromwell, Edward C Kuan, Jivianne Lee, Michael J Link, James K Liu, Patricia Loftus, Nyall R London, Erin L McKean, Kibwei A McKinney, L Madison Michael, Gurston G Nyquist, Zara M Patel, Mindy Rabinowitz, Sanjeet V Rangarajan, Kenneth D Rodriguez, Nicholas R Rowan, Rodney J Schlosser, Kafui Searyoh, Raymond F Sekula, Timothy L Smith, Carl Snyderman, Satyan B Sreenath, Dennis M Tang, Brian D Thorp, Eric W Wang, Marilene B Wang, Bradford A Woodworth, Garret Choby
{"title":"June 4: International Skull Base Surgery Day.","authors":"David A Gudis, Benjamin S Bleier, Jean Anderson Eloy, James J Evans, Juan Carlos Fernandez-Miranda, Paul A Gardner, Mathew Geltzeiler, Jessica W Grayson, Richard J Harvey, Elisa A Illing, David W Kennedy, Cristine Klatt-Cromwell, Edward C Kuan, Jivianne Lee, Michael J Link, James K Liu, Patricia Loftus, Nyall R London, Erin L McKean, Kibwei A McKinney, L Madison Michael, Gurston G Nyquist, Zara M Patel, Mindy Rabinowitz, Sanjeet V Rangarajan, Kenneth D Rodriguez, Nicholas R Rowan, Rodney J Schlosser, Kafui Searyoh, Raymond F Sekula, Timothy L Smith, Carl Snyderman, Satyan B Sreenath, Dennis M Tang, Brian D Thorp, Eric W Wang, Marilene B Wang, Bradford A Woodworth, Garret Choby","doi":"10.1055/a-2538-4080","DOIUrl":"10.1055/a-2538-4080","url":null,"abstract":"","PeriodicalId":16513,"journal":{"name":"Journal of Neurological Surgery Part B: Skull Base","volume":"86 3","pages":"243-244"},"PeriodicalIF":0.9,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12064291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Teppei Takeda, Scott Hardison, Kazuhiro Omura, Yudo Ishii, Ryosuke Mori, Adam J Kimple, Brent A Senior, Nobuyoshi Otori, Christine Klatt-Cromwell, Brian D Thorp
{"title":"Innovative Orbital Periosteum Suturing Technique for Endoscopic Medial Orbital Wall Reconstruction.","authors":"Teppei Takeda, Scott Hardison, Kazuhiro Omura, Yudo Ishii, Ryosuke Mori, Adam J Kimple, Brent A Senior, Nobuyoshi Otori, Christine Klatt-Cromwell, Brian D Thorp","doi":"10.1055/a-2413-3051","DOIUrl":"10.1055/a-2413-3051","url":null,"abstract":"<p><strong>Background: </strong>Advances in endoscopic orbital surgery have sparked discussion regarding reconstructive procedures for medial orbital wall defects following tumor removal. This study describes an innovative orbital periosteal suturing technique that addresses the functional and aesthetic concerns created by orbital surgery.</p><p><strong>Objective: </strong>Comprehensive clinical evaluation of a novel orbital periosteal suturing technique for endoscopic medial orbital wall reconstruction.</p><p><strong>Methods: </strong>A retrospective chart review identified five patients who underwent endoscopic transnasal resection and subsequent orbital periosteal suturing for reconstruction. The surgical approach involved a binostril transseptal technique to create a broad surgical corridor. The postoperative follow-up was 13.4 ± 1.8 months.</p><p><strong>Results: </strong>In the five patients, the mean age was 47.6 ± 13.0 years and the lesions were predominantly distributed on the left side (60%). Reconstruction time with the orbital periosteal suture procedure averaged 47.2 ± 6.6 minutes, employing four to five stitches. No patients experienced short-term complications such as visual acuity defect, new or exacerbated diplopia, or cranial nerve palsy within 2 weeks, and no long-term complications such as enophthalmos or prolonged diplopia were observed.</p><p><strong>Conclusion: </strong>Orbital periosteal suturing is an effective and resource-efficient technique for endoscopic reconstruction of the medial orbital wall. Surgeons may consider this method among the available options for orbital reconstruction, representing a novel advancement in the field.</p>","PeriodicalId":16513,"journal":{"name":"Journal of Neurological Surgery Part B: Skull Base","volume":"86 5","pages":"556-561"},"PeriodicalIF":0.9,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12396872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Paranasal Sinus Visualization Capabilities of a Novel Articulating Rigid-Flexible Endoscope: A Cadaveric Study.","authors":"Allen L Feng, Barak Ringel, Eric H Holbrook","doi":"10.1055/s-0044-1791575","DOIUrl":"10.1055/s-0044-1791575","url":null,"abstract":"<p><strong>Introduction: </strong>Rigid endoscopes have allowed surgeons to safely perform endoscopic sinus surgery. However, their rigid nature creates inherent visualization limitations. The study herein looks to assess the visualization potential of a novel articulating rigid-flexible endoscope when compared with traditional rigid and flexible nasal endoscopes.</p><p><strong>Methods: </strong>A new articulating endoscope capable of bending its distal tip and extending beyond the point of angulation was compared with 0- and 30-degree 4.0-mm rigid endoscopes, and a 3.7-mm flexible nasopharyngoscope in their ability to visualize predefined anatomic landmarks within the maxillary, sphenoid, and frontal sinuses. Visible markers were placed at applicable landmarks using image guidance in a total of five cadaveric heads. The ability to visualize these intrasinus anatomic landmarks was recorded for each scope.</p><p><strong>Results: </strong>When inspecting the surgically naive anatomy of all sinus ostia and predefined anatomic landmarks, the articulating endoscope had superior visualization ( <i>p</i> < 0.01) compared with the 0-degree, 30-degree, and flexible endoscopes throughout all sinuses (maxillary sinus: 62.5, 0, 5, and 0%, respectively; sphenoidal sinus: 92.5, 27.5, 37.5, and 40%, respectively; frontal sinus: 51.4, 5.7, 20, and 37.1%, respectively). After performing a Draf IIa, the articulating endoscope was able to visualize 100% of the predefined frontal sinus landmarks compared with 22.9, 45.7, and 65.7% for the 0-degree, 30-degree, and flexible endoscopes, respectively ( <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>The articulating rigid-flexible endoscope is superior in reaching and visualizing anatomic landmarks within the paranasal sinuses, compared with standard endoscopes.</p>","PeriodicalId":16513,"journal":{"name":"Journal of Neurological Surgery Part B: Skull Base","volume":"86 5","pages":"529-537"},"PeriodicalIF":0.9,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12396861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anirudh Saraswathula, Mohammed N Ullah, Jacklyn Liu, Yoko Takahashi, Arushi Mahajan, Simonetta Battocchio, Paolo Bossi, Paolo Castelnuovo, Carla Facco, Marco Ferrari, Dawn Carnell, Martin D Forster, Alessandro Franchi, Amrita Jay, Davide Lombardi, Valerie J Lund, Davide Mattavelli, Piero Nicolai, Vittorio Rampinelli, Fausto Sessa, Shirley Y Su, Mario Turri-Zanoni, Laura Ardighieri, Erin McKean, Matt Lechner, Ehab Hanna, Nyall R London
{"title":"International, Multi-Institutional Evaluation of Practice Patterns and Outcomes for Recurrent and Metastatic Sinonasal Undifferentiated Carcinoma.","authors":"Anirudh Saraswathula, Mohammed N Ullah, Jacklyn Liu, Yoko Takahashi, Arushi Mahajan, Simonetta Battocchio, Paolo Bossi, Paolo Castelnuovo, Carla Facco, Marco Ferrari, Dawn Carnell, Martin D Forster, Alessandro Franchi, Amrita Jay, Davide Lombardi, Valerie J Lund, Davide Mattavelli, Piero Nicolai, Vittorio Rampinelli, Fausto Sessa, Shirley Y Su, Mario Turri-Zanoni, Laura Ardighieri, Erin McKean, Matt Lechner, Ehab Hanna, Nyall R London","doi":"10.1055/s-0044-1791573","DOIUrl":"10.1055/s-0044-1791573","url":null,"abstract":"<p><strong>Objectives: </strong>The aims of this study were to analyze the clinical characteristics of patients with recurrent and metastatic sinonasal undifferentiated carcinoma (SNUC) and evaluate the current treatment strategies to help guide future management.</p><p><strong>Design: </strong>This is a retrospective cohort study.</p><p><strong>Setting: </strong>The study was conducted at six international tertiary treatment centers.</p><p><strong>Participants: </strong>Patients with documented diagnoses of recurrent or metastatic SNUC since 1983 were included in the study.</p><p><strong>Main outcome measures: </strong>Patient demographics and clinical characteristics were collected. Primary outcome measures included disease-specific survival (DSS), overall survival (OS), and time to recurrence (TTR) following initial treatment. Further univariable and multivariable analyses were performed to assess for prognostic factors.</p><p><strong>Results: </strong>A total of 97 patients with a mean (standard deviation [SD]) age of 52.4 (15.6) were identified, 15 of whom presented with metastatic SNUC and 90 of whom developed recurrence. Management in both populations was widely variable. For patients with metastatic disease, the 1-year DSS probability was 33.3% (95% confidence interval [CI], 10.8-100%). For patients with recurrent SNUC, the 1- and 5-year DSS probabilities were 45.7% (95% CI, 31.9-65.6%) and 8.6% (95% CI, 2.9-25.3%), respectively. The median (interquartile range [IQR]) TTR was 8 months (3-18.5 months). Multivariable analyses revealed a significant association between orbital involvement on initial presentation and TTR (hazard ratio [HR] = 3.28; 95% CI, 1.45-7.42; <i>p</i> = 0.004).</p><p><strong>Conclusions: </strong>To our knowledge, this is the first study addressing metastatic and recurrent SNUC based on a large patient cohort. Orbital extension of the primary SNUC may predict a higher probability of recurrence following treatment, suggesting the possible utility of a more aggressive treatment in this subgroup of patients. A heterogenous patient population and wide variability in management emphasize the challenges in standardizing care; however, dismal survival rates demonstrate the necessity for further evaluation of current approaches to improve evidence-based recommendations.</p>","PeriodicalId":16513,"journal":{"name":"Journal of Neurological Surgery Part B: Skull Base","volume":"86 5","pages":"538-546"},"PeriodicalIF":0.9,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12396877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maikerly Reyes, Patrick Kelly, KiChang Kang, Justin Williams, Anish Sathe, Allison Kayne, India Shelley, Giyarpuram Prashant, David Bray, Mark T Curtis, James J Evans
{"title":"Effect of Extent of Resection and Adjuvant Radiation on Recurrence of BRAF versus β-Catenin-Mutated Craniopharyngioma: A Single Institutional Case Series.","authors":"Maikerly Reyes, Patrick Kelly, KiChang Kang, Justin Williams, Anish Sathe, Allison Kayne, India Shelley, Giyarpuram Prashant, David Bray, Mark T Curtis, James J Evans","doi":"10.1055/s-0044-1791576","DOIUrl":"10.1055/s-0044-1791576","url":null,"abstract":"<p><strong>Objectives: </strong>The two histologic subtypes of craniopharyngiomas (CPs), papillary and adamantinomatous, harbor mutually exclusive mutations of BRAF V600E and CTNNB1, respectively. Studies suggest that subtotal resection (STR) plus adjuvant radiation therapy (XRT) may result in similar progression-free survival (PFS) as gross total resection (GTR). We hypothesized that STR ± XRT and GTR result in similar PFS for both BRAF and β-catenin-mutated CPs.</p><p><strong>Design: </strong>Patients who were surgically treated for a primary CP between 2001 and 2023 at a single institution were included. Immunohistochemical studies were performed retrospectively using BRAF and β-catenin antibodies. Patients with missing immunohistochemistry (IHC) diagnosis were excluded. Differences in PFS for STR ± XRT and GTR groups were assessed with a log-rank test, stratified by BRAF and β-catenin IHC status.</p><p><strong>Results: </strong>A total of 77 patients with CP were screened. IHC data were available for 50 patients; 20 had a BRAF mutation, and 30 had a β-catenin mutation. Among BRAF patients, 11 underwent GTR; 9 had STR, and 5 had adjuvant XRT. Among β-catenin patients, 14 underwent GTR; 16 had STR, and 6 had adjuvant XRT. For BRAF patients with GTR, the median PFS was not reached; for BRAF patients with STR ± XRT, the median PFS was 150 days ( <i>p</i> < 0.01, log-rank test). For β-catenin patients with GTR, the median PFS was 1,813 days; for β-catenin patients with STR ± XRT, the median PFS was not reached ( <i>p</i> = 0.80, log-tank test).</p><p><strong>Conclusions: </strong>Both GTR and STR ± XRT seemed to offer similar PFS outcomes only for patients with β-catenin-mutated CP. For patients with BRAF-mutated CP, a greater extent of resection was significantly associated with prolonged PFS.</p>","PeriodicalId":16513,"journal":{"name":"Journal of Neurological Surgery Part B: Skull Base","volume":"86 5","pages":"570-576"},"PeriodicalIF":0.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12396883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dana N Eitan, Taylor B Cave, Bernard R Bendok, Chandan Krishna, Devyani Lal, Amar Miglani, Naresh P Patel, Devi P Patra, Ali Turkmani, Michael J Marino
{"title":"Outpatient Endocrine Protocol and Testing Coincides with Reduced Length of Postpituitary Surgery Admission.","authors":"Dana N Eitan, Taylor B Cave, Bernard R Bendok, Chandan Krishna, Devyani Lal, Amar Miglani, Naresh P Patel, Devi P Patra, Ali Turkmani, Michael J Marino","doi":"10.1055/s-0044-1791574","DOIUrl":"10.1055/s-0044-1791574","url":null,"abstract":"<p><strong>Objective: </strong>The study objective was to compare the length of stay (LOS) and the proportion of one-night admissions before and after the implementation of an endocrine monitoring protocol following endoscopic transsphenoidal surgery (ETSS) for pituitary adenoma.</p><p><strong>Methods: </strong>Patients who underwent transsphenoidal pituitary adenoma resection between July 1, 2018, and September 9, 2022, were identified, and divided into two cohorts before and after the implementation of the monitoring protocol. The overall LOS and number of nights of admission were recorded. Readmission within 30 days after surgery was also recorded. The number of outpatient laboratory tests performed and the time to the first test were also noted.</p><p><strong>Results: </strong>Thirty patients were identified in the preprotocol group and 60 in the postprotocol group. The average admission length in the preprotocol group was significantly longer than the average admission length in the postprotocol group (2.4 vs. 1.7 days, <i>p</i> = 0.004). The percentage of one-night admissions increased from 13 to 57% ( <i>p</i> < 0.001). There were no significant differences in readmission rates between the two groups ( <i>p</i> = 0.681). The number of laboratory encounters increased from a mean of 1.38 to 2.40 ( <i>p</i> = 0.030), while the time to the first test decreased from a mean of 3.43 to 2.36 days ( <i>p</i> = 0.049).</p><p><strong>Conclusion: </strong>Patients admitted after ETSS for pituitary adenoma had shorter hospital stay and greater proportion of one-night admission with the implementation of an endocrine monitoring protocol. The all-cause readmission rate was not statistically different between the two groups. Through aggressive outpatient laboratory monitoring, one-night admission for ETSS may be feasible.</p>","PeriodicalId":16513,"journal":{"name":"Journal of Neurological Surgery Part B: Skull Base","volume":"86 5","pages":"577-582"},"PeriodicalIF":0.9,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12396870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Papazian, Justin Cottrell, Lydia Pan, Emily Kay-Rivest, David R. Friedmann, Daniel Jethanamest, Douglas Kondziolka, Donato Pacione, Chandranath Sen, John G. Golfinos, J. Thomas Roland Jr., Sean O. McMenomey
{"title":"Characterizing Hearing Outcomes Following Treatment of Cerebellopontine Angle Meningiomas","authors":"Michael Papazian, Justin Cottrell, Lydia Pan, Emily Kay-Rivest, David R. Friedmann, Daniel Jethanamest, Douglas Kondziolka, Donato Pacione, Chandranath Sen, John G. Golfinos, J. Thomas Roland Jr., Sean O. McMenomey","doi":"10.1055/a-2399-0081","DOIUrl":"https://doi.org/10.1055/a-2399-0081","url":null,"abstract":"<p>\u0000<b>Objectives</b> To characterize treatment and hearing outcomes for cerebellopontine angle (CPA) meningiomas with inherent risks of hearing loss and identify predictors of hearing loss for surgically treated lesions.</p> <p>\u0000<b>Design</b> Retrospective chart review.</p> <p>\u0000<b>Setting</b> Tertiary care medical center.</p> <p>\u0000<b>Participants</b> Adult patients with CPA meningiomas impinging upon cranial nerve VIII and/or pretreatment hearing loss managed with microsurgery or stereotactic radiosurgery (SRS) with Gamma Knife at our center between 2012 and 2023.</p> <p>\u0000<b>Main Outcome Measures</b> Hearing preservation rate was determined from analysis of patients with pretreatment serviceable hearing for whom hearing-preserving treatment was attempted. Surgical patients were further analyzed using multivariable Cox proportional hazards regression models to identify factors predictive of postoperative hearing loss.</p> <p>\u0000<b>Results</b> We identified 80 patients with CPA meningiomas meeting inclusion criteria who were managed with either microsurgery (43, 54%) or radiosurgery (37, 46%). Following SRS, hearing was preserved in 88% of cases. Following microsurgery, hearing was preserved in 71% of patients—all patients who lost hearing had tumors involving the internal auditory canal (IAC). Among surgical patients only, multivariable analysis accounting for preoperative hearing, recurrence status, lesion size, and patient age, the preoperative imaging finding that the CPA meningioma surrounded the vestibulocochlear nerve was significantly associated with hearing loss (hazard ratio: 10.3, 95% confidence interval: 1.3–81.4, <i>p</i> = 0.02).</p> <p>\u0000<b>Conclusion</b> Most patients with meningiomas of the CPA can experience preservation of hearing, even when there is risk of hearing loss based on pretreatment evaluation. IAC invasion and surrounding of eighth nerve by tumor may portend poorer hearing outcomes in surgically managed patients.</p> ","PeriodicalId":16513,"journal":{"name":"Journal of Neurological Surgery Part B: Skull Base","volume":"65 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142212329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}