Journal of neurosurgical sciences最新文献_第8页

The prognostic value of emergency microsurgical clipping of ruptured anterior circulation aneurysms. 对破裂的前循环动脉瘤进行紧急显微外科夹闭手术的预后价值。

IF 1.3 4区医学

Journal of neurosurgical sciences Pub Date : 2024-07-01 DOI: 10.23736/S0390-5616.24.06236-2

Biagia LA Pira, Giancarlo D'Andrea, Paolo Ferroli, Melina Castiglione, Giovanni Pennisi, Giulio Maira, Placido Bruzzaniti

{"title":"The prognostic value of emergency microsurgical clipping of ruptured anterior circulation aneurysms.","authors":"Biagia LA Pira, Giancarlo D'Andrea, Paolo Ferroli, Melina Castiglione, Giovanni Pennisi, Giulio Maira, Placido Bruzzaniti","doi":"10.23736/S0390-5616.24.06236-2","DOIUrl":"https://doi.org/10.23736/S0390-5616.24.06236-2","url":null,"abstract":"Background: The treatment of aneurysmal subarachnoid hemorrhage poses a formidable challenge, given the high mortality rate and associated mortality. Current recommendations are for treatment to be initiated within 24 hours of diagnosis.Methods: In our study, we compared a cohort of 66 patients who received prompt microsurgical treatment within 6 hours of diagnosis with a cohort of 51 patients who received prompt microsurgical treatment within 12 hours of diagnosis.Results: The modified Rankin Scale was utilized to evaluate the follow-up of patients at 30 days, 12 months, and 18 months following surgery. We performed a parametric comparison of the distributions of the means of groups, and our results indicate that treatment within 6 hours of diagnosis results in a lower incidence of obstructive hydrocephalus and a more favorable outcome.Conclusions: A favorable outcome was observed in patients who were treated within 6 hours. The availability of a specialized vascular team ensures the highest levels of care.","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141468619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unraveling the controversy: high-dose steroids in spinal cord injury. Forty years of inquiry. 解开争议：脊髓损伤中的大剂量类固醇。四十年的探索

IF 1.9 4区医学

Journal of neurosurgical sciences Pub Date : 2024-06-01 Epub Date: 2024-03-14 DOI: 10.23736/S0390-5616.24.06238-6

Rossella Rispoli, Barbara Cappelletto

引用次数: 0

Interleukin-17 receptor D is a favorable biomarker of glioblastoma. 白细胞介素-17受体D是胶质母细胞瘤的一个有利的生物标志物。

IF 1.3 4区医学

Journal of neurosurgical sciences Pub Date : 2024-06-01 Epub Date: 2022-04-05 DOI: 10.23736/S0390-5616.22.05552-7

Yang Liu, Mingshui Xie, Ye Zhou, Lili Che, Bin Zhang

{"title":"Interleukin-17 receptor D is a favorable biomarker of glioblastoma.","authors":"Yang Liu, Mingshui Xie, Ye Zhou, Lili Che, Bin Zhang","doi":"10.23736/S0390-5616.22.05552-7","DOIUrl":"10.23736/S0390-5616.22.05552-7","url":null,"abstract":"Background: Glioblastoma (GBM) is the most frequent glioma in adults. The prognosis of GBM is very poor and new prognostic biomarkers are in urgent need to better select high-risk patients and guide the individual treatments.Methods: In our study, we compared the expression of interleukin-17 receptor D (IL17RD) between GBMs and normal tissues from TCGA database, and detected IL17RD mRNA in 17 fresh GBM pairs with qPCR. With immunohistochemistry, we investigated the expression of IL17RD in 156 GBM tissues and further evaluated its clinical significance. The associations between IL17RD and clinicopathological factors were assessed by Chi-square test. The prognostic significance of IL17RD was evaluated by univariate analysis with Kaplan-Meier method, and by multivariate analysis with Cox-regression Hazard model.Results: The TPMs and mRNAs of IL17RD in GBM were substantially lower than those in normal brain tissues. The rates of low or high expression of IL17RD accounted for 41.67% and 58.33% respectively. IL17RD was significantly associated with higher survival rates of GBM. The 3-year overall survival rates of patients with low and high IL17RD were 7.2% and 19.5% respectively. In the Cox-regression model, the IL17RD expression was defined as an independent prognostic biomarker of GBM. Patients with high IL17RD expression had a more favorable outcome than those with low IL17RD.Conclusions: High IL17RD expression was an independent prognostic indicator of GBM, suggesting a more favorable prognosis. Our results suggested that IL17RD detection may help find the high-risk patients which may receive more severe surveillance and more individual treatments.","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":"1 1","pages":"320-326"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41436628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is endovascular treatment alone as effective and safe as that with preceding intravenous thrombolysis for acute ischemic stroke? A meta-analysis of randomized controlled trials. 对于急性缺血性脑卒中，单纯血管内治疗是否与静脉溶栓治疗同样有效和安全？随机对照试验荟萃分析。

IF 1.9 4区医学

Journal of neurosurgical sciences Pub Date : 2024-06-01 Epub Date: 2023-06-30 DOI: 10.23736/S0390-5616.23.06058-7

Mohammad O Khan, Syeda A Shah, Samar Mahmood, Ashnah Aijaz, Nadia N Jatoi, Firzah Shakil, Khushboo Nusrat, Omer M Siddiqui, Ishaque Hameed

{"title":"Is endovascular treatment alone as effective and safe as that with preceding intravenous thrombolysis for acute ischemic stroke? A meta-analysis of randomized controlled trials.","authors":"Mohammad O Khan, Syeda A Shah, Samar Mahmood, Ashnah Aijaz, Nadia N Jatoi, Firzah Shakil, Khushboo Nusrat, Omer M Siddiqui, Ishaque Hameed","doi":"10.23736/S0390-5616.23.06058-7","DOIUrl":"10.23736/S0390-5616.23.06058-7","url":null,"abstract":"Introduction: This meta-analysis aimed to evaluate the safety and efficacy of direct endovascular therapy (EVT) and bridging therapy (EVT with preceding intravenous thrombolysis i.e. IVT), in acute anterior circulation, large vessel occlusion stroke.Evidence acquisition: Following the PRISMA guidelines, a systematic literature review of the English language literature was conducted using PubMed, Cochrane CENTRAL, SCOPUS and ClinicalTrials.gov. Outcomes of interest were measured by the modified Rankin Scale (mRS), and included: no disability (mRS0), no significant disability despite some symptoms (mRS1), slight disability (mRS2), moderate disability (mRS3), moderately severe disability (mRS4), severe disability (mRS5), mortality (mRS6). Additionally, we inspected patients having excellent outcome, functional independence outcome, and poor outcome, along with successful reperfusion and intracranial hemorrhage. We calculated pooled risk ratios (RRs) and their corresponding 95% confidence intervals (CI).Evidence synthesis: A total of seven RCTs involving 2,392 patients were finally included. The chances of achieving successful reperfusion were significantly more with IVT+EVT as compared to EVT alone (RR: 0.97; 95% CI: 0.94, 1.00; P=0.03) (I2=0%). There was no significant difference in the number of patients having outcomes ranging from mRS0 to mRS6, excellent outcome, functional independence, poor outcome or incidence of intracranial hemorrhage, who underwent either EVT alone or IVT+EVT.Conclusions: Additional trials are needed to determine if the absence of significant differences is due to insufficient sample size or if the combination therapy is truly not beneficial.","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":"338-347"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9690197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Operator perceived advantage of virtual surgical rehearsal in pediatric neurosurgical oncology: a preliminary experience. 小儿神经外科肿瘤学中虚拟手术预演的操作者感知优势：初步经验。

IF 1.3 4区医学

Journal of neurosurgical sciences Pub Date : 2024-06-01 Epub Date: 2023-11-06 DOI: 10.23736/S0390-5616.23.06152-0

Roberto Premuselli, Carmen D'Amore, Matteo Barba, Alessandra Marasi, Giada Del Baldo, Alessandro DE Benedictis, Eleonora Piccirilli, Giovanna S Colafati, Angela Mastronuzzi, Carlo E Marras, Andrea Carai

引用次数: 0

A novel 3D anatomical visualization system to avoid injuries of nerves in retrosigmoid approach. 新颖的三维解剖可视化系统，避免后穹隆入路损伤神经。

IF 1.9 4区医学

Journal of neurosurgical sciences Pub Date : 2024-06-01 Epub Date: 2023-04-27 DOI: 10.23736/S0390-5616.23.05955-6

Domenico LA Torre, Attilio Della Torre, Antonino Germanò, Dorotea Pugliese, Erica Lo Turco, Paola Lacroce, Alberto Romano, Angelo Lavano, Francesco Tomasello

{"title":"A novel 3D anatomical visualization system to avoid injuries of nerves in retrosigmoid approach.","authors":"Domenico LA Torre, Attilio Della Torre, Antonino Germanò, Dorotea Pugliese, Erica Lo Turco, Paola Lacroce, Alberto Romano, Angelo Lavano, Francesco Tomasello","doi":"10.23736/S0390-5616.23.05955-6","DOIUrl":"10.23736/S0390-5616.23.05955-6","url":null,"abstract":"The retro-sigmoid approach (RA), widely used during different neurosurgical procedures, is burdened by the risk of injuries of the nerves that cross that region contributing to possible postoperative complications. By using, anatomage table (AT), a novel 3D anatomical visualization system, we described the nerves passing through the retromastoid area including the great occipital nerve (GON), the lesser occipital nerve (LON) and the great auricular nerve (GAN), and their courses from the origins, till terminal branches. Moreover, using dedicated software, we measured distances between the nerves and well-recognizable bony landmarks. After identifying the nerves and their distances from bony landmarks, we observed that the safest and risk-free skin incision should be made in an area delimited, superiorly from the superior nuchal line (or slightly higher), and inferiorly from a plane passing at 1-1.5 cm above the mastoid tip. The lateral aspect of such an area should not exceed 9.5-10 cm from the inion, while the medial one should be more than 7 cm far from the inion. This anatomical information has been useful in defining anatomical landmarks and reducing the risk of complications, mainly related to nerve injury, in RA. In-depth neuroanatomic knowledge of the cutaneous nerves of the retromastoid area is essential to minimize the complications related to their injury during different neurosurgical approaches. Our findings suggest that the AT is a reliable tool to enhance understanding of the anatomy, and thus contributing to the refinement of surgical techniques.","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":"348-357"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9358268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plica mediana dorsalis as a potential risk for spine surgery. 背内侧皱襞作为脊柱手术的潜在风险。

IF 1.3 4区医学

Journal of neurosurgical sciences Pub Date : 2024-06-01 Epub Date: 2023-10-25 DOI: 10.23736/S0390-5616.23.06097-6

Angelo Lavano, Attilio Della Torre, Giusy Guzzi, Domenico LA Torre

引用次数: 0

Environmental cold exposure precipitating Moyamoya disease. 环境寒冷暴露诱发烟雾病。

IF 1.3 4区医学

Journal of neurosurgical sciences Pub Date : 2024-06-01 Epub Date: 2023-11-06 DOI: 10.23736/S0390-5616.23.06149-0

Shambaditya DAS, Alak Pandit, Biman K Ray, Arindam Santra, Souvik Dubey

引用次数: 0

An understimated maneuver for oculomotor nerve palsy due to posterior communicating artery aneurysm: the opening of the anterior petroclinoid ligament. A technical note. 治疗后交通动脉瘤引起的眼球运动神经麻痹的低估手法：打开前瓣韧带。技术说明。

IF 1.3 4区医学

Journal of neurosurgical sciences Pub Date : 2024-06-01 Epub Date: 2023-05-15 DOI: 10.23736/S0390-5616.23.06020-4

Biagia LA Pira, Veronica Picotti, Alessandro Frati, Alessandro Pesce, Giancarlo D'Andrea

{"title":"An understimated maneuver for oculomotor nerve palsy due to posterior communicating artery aneurysm: the opening of the anterior petroclinoid ligament. A technical note.","authors":"Biagia LA Pira, Veronica Picotti, Alessandro Frati, Alessandro Pesce, Giancarlo D'Andrea","doi":"10.23736/S0390-5616.23.06020-4","DOIUrl":"10.23736/S0390-5616.23.06020-4","url":null,"abstract":"Posterior communicating artery aneurysms (PcomAs) present with oculomotor nerve (OMN) palsy in 20-30% of cases, and the sudden onset of OMN palsy has to raise the suspicion of rupture, until proven otherwise. The surgical technique is described in a stepwise fashion. An illustrative case is reported: a 57-year-old female was admitted to our department with the diagnosis of a right sided-PcomA. Three months before the admission, when she harbored with the acute onset of complete ptosis, diplopia, orbital pain, impairment of the medial, upward, and downward gaze, with no pupil dysfunction. The origin of the Pcom and the neck of the aneurysm were easily identified and the aneurysm was clipped. Then, we followed the OMN and cut for less than 4 mm the above-lying anterior petroclinoid ligament (APL) to obtain nerve release. Although few cases are described in the literature, and ours represents a single case, we support that this maneuver should be introduced in the clinical practice of expert neurosurgeons dealing with vascular pathologies, such as the opening of the falciform ligament occurs for the decompression of the optical nerve.","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":"358-364"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9467722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between the morphological features of the central sulcus and the somatomotory representation: anatomo-functional evaluation of neuroplasticity through nTMS. 中央沟的形态特征与躯体表征之间的关联：通过 nTMS 对神经可塑性进行解剖功能评估。

IF 1.9 4区医学

Journal of neurosurgical sciences Pub Date : 2024-04-01 Epub Date: 2023-02-01 DOI: 10.23736/S0390-5616.22.05857-X

Augusto Leone, Francesco Tomaiuolo, Giovanni Raffa, Antonino F Germanò, Francesco Carbone, Antonio Colamaria, Giada Cangemi

{"title":"Association between the morphological features of the central sulcus and the somatomotory representation: anatomo-functional evaluation of neuroplasticity through nTMS.","authors":"Augusto Leone, Francesco Tomaiuolo, Giovanni Raffa, Antonino F Germanò, Francesco Carbone, Antonio Colamaria, Giada Cangemi","doi":"10.23736/S0390-5616.22.05857-X","DOIUrl":"10.23736/S0390-5616.22.05857-X","url":null,"abstract":"In recent years navigated transcranial magnetic stimulation (nTMS) has emerged as a useful tool for the preoperative mapping of brain cortical areas surrounding neoplastic tissues allowing for maximal safe tumor resection and minimizing new postoperative permanent neurological deficits. Three patients presenting with an intrinsic brain tumor (one metastasis from mammary carcinoma, one high-grade glioma, and one low-grade glioma) located within or in close relationship to the central sulcus were enrolled for this study. The MRI-based morphological and nTMS mapping of the central sulcus of the intact hemisphere was complemented by the examination of the contralateral region harboring the lesion. The findings were independently compared, in search of evidence of tumor-induced neuroplasticity and/or signs of parenchymal dislocation/infiltration caused by the tumor. An individual description of each mapping session is provided. Significant discrepancies were observed between morphological MRI and functional nTMS mapping in two patients, demonstrating a tumor-induced shift of distinct cortical areas controlling hand and/or facial movements. In the cases of gliomas, a lower MT was detected in the lesioned hemisphere, possibly due to increased electrical excitability caused by the tumor itself. The integration of MRI-based morphological mapping of the central sulcus with the detection of its somatomotor representations through nTMS can assist neurosurgeons when planning the resection of a motor-eloquent tumor, stratifying the risks of secondary neurological deficits. The combination of the two preoperative techniques is able to disclose tumor-induced neural plasticity subsequently guiding a more precise resection.","PeriodicalId":16504,"journal":{"name":"Journal of neurosurgical sciences","volume":" ","pages":"238-246"},"PeriodicalIF":1.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10597976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0