Chensi Ouyang, Alexander Wang, Morgan Briggs, Grace Maszy, Hannah Lewis, Isabel Green, Meryl Alappattu, Georgine Lamvu
{"title":"Changes in Sexual Function After Minimally Invasive Hysterectomy in Reproductive-Aged Women: A Systematic Review and Meta-Analysis.","authors":"Chensi Ouyang, Alexander Wang, Morgan Briggs, Grace Maszy, Hannah Lewis, Isabel Green, Meryl Alappattu, Georgine Lamvu","doi":"10.1016/j.jmig.2025.05.010","DOIUrl":"10.1016/j.jmig.2025.05.010","url":null,"abstract":"<p><strong>Objective: </strong>One primary concern among patients undergoing minimally invasive hysterectomy (MIH) is postsurgical sexual function. Conflicting evidence exists due to variability in the sexual function measures, the menopause status of patients, and the inclusion of data from laparotomies. The purpose of this systematic review and meta-analysis was to evaluate the effects of MIH on sexual function in premenopausal women while accounting for these confounders.</p><p><strong>Data sources: </strong>Data search was conducted in PubMed, Google Scholar, Cochrane Central Register of Controlled Trials, Scopus, Science Direct, ProQuest, and EBSCO from inception to December 31, 2024.</p><p><strong>Methods: </strong>The initial search yielded 1124 papers, and 8 studies met eligibility criteria. Eligibility criteria included reporting on sexual function using the Female Sexual Function Index (FSFI), MIH for benign and nonurogynecological conditions, and a study population of premenopausal women. MIH routes included laparoscopic and vaginal surgeries. The primary outcome of interest was a change in the total FSFI score and domains pre- and postsurgery.</p><p><strong>Tabulation, integration, and results: </strong>Meta-analysis was performed for each outcome using Cochrane Review Manager 5. Mean differences and 95% confidence intervals (CI) were calculated using pre- and postsurgery FSFI scores. The mean difference between pre- and posthysterectomy FSFI scores showed a small statistically significant improvement in sexual function after surgery: -1.54 (CI -2.83, -0.25). There were small statistically significant improvements in sexual function in the domains of desire (-0.75, CI -1.34, -0.17), arousal (-0.85, CI -1.46, -0.25), orgasm (-0.46, CI -0.81, -0.12), and satisfaction (-0.69, CI -1.20, -0.18). There were no statistically significant changes in the domains of lubrication and pain. The level of evidence is low, with moderate heterogeneity and risk of bias.</p><p><strong>Conclusion: </strong>After hysterectomy with ovarian preservation, premenopausal women report small, yet statistically significant, improvement in overall sexual function, which is not likely clinically significant.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does Concurrent Burch Colposuspension Reduce Postoperative Stress Urinary Incontinence in Laparoscopic Sacrocolpopexy? An Interim Analysis.","authors":"Keisuke Oyama, Shoko Ikeda, Makiko Yuda","doi":"10.1016/j.jmig.2025.05.009","DOIUrl":"10.1016/j.jmig.2025.05.009","url":null,"abstract":"<p><strong>Study objective: </strong>This study aimed to evaluate whether performing Burch colposuspension (BC) concurrently with laparoscopic sacrocolpopexy (LSC) reduces the incidence of postoperative de novo stress urinary incontinence (SUI) and other urinary dysfunctions in patients with pelvic organ prolapse (POP).</p><p><strong>Design: </strong>A prospective cohort study conducted at a single center.</p><p><strong>Setting: </strong>The study was performed at a regional hospital specializing in gynecologic surgery.</p><p><strong>Patients: </strong>Twenty patients with ≥stage II POP scheduled for LSC (July 2023-June 2024), without prior prolapse/incontinence treatment, were included regardless of preoperative urinary incontinence status. Patients chose their preferred procedure after comprehensive counseling on risks and benefits; randomization was not performed.</p><p><strong>Interventions: </strong>The LSC group underwent LSC alone, while the LSC+BC group received BC concurrently with LSC. Subjective symptoms were assessed using standardized questionnaires, including the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) and the King's Health Questionnaire (KHQ), as well as a cough stress test, preoperatively and at 3 months postoperatively.</p><p><strong>Measurements and main results: </strong>Interim analysis showed a median [interquartile range] ICIQ-SF change of -3 [-6, 0] in the LSC group versus 0 [-5, 3] in the LSC+BC group (p = .360). The KHQ Incontinence Impact scale changed by -17 [-33, 25] for LSC versus 0 [-33, 0] for LSC+BC (p = 1.000), and severity scores were -17 [-32, 5] versus 0 [-5, 22] (p = .305). Although LSC tended to yield better scores, the differences were not statistically significant. The median operative time was prolonged 52 minutes in the LSC+BC group (p < .001), and 1 bladder injury occurred in this group.</p><p><strong>Conclusion: </strong>This preliminary study suggests that adding BC to LSC did not significantly improve postoperative de novo SUI but increased operative time and complication risks. These findings suggest that routine use of BC in minimally invasive sacrocolpopexy may not be beneficial.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danielle L Snyder, Silvana Sidhom, Corinne E Chatham, Sophie G Tillotson, Ruben D Zapata, François Modave, Miranda Solly, Amira Quevedo, Nash S Moawad
{"title":"Utilizing Artificial Intelligence: Machine Learning Algorithms to Develop a Preoperative Endometriosis Prediction Model.","authors":"Danielle L Snyder, Silvana Sidhom, Corinne E Chatham, Sophie G Tillotson, Ruben D Zapata, François Modave, Miranda Solly, Amira Quevedo, Nash S Moawad","doi":"10.1016/j.jmig.2025.05.003","DOIUrl":"10.1016/j.jmig.2025.05.003","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the predictive value of clinical features in the diagnosis of endometriosis by utilizing machine learning algorithms (MLAs), aiming to develop an accurate, explainable prediction model.</p><p><strong>Design: </strong>Retrospective case-control study from 2011 to 2022.</p><p><strong>Setting: </strong>Tertiary referral center specializing in pelvic pain and minimally invasive gynecologic surgery.</p><p><strong>Participants: </strong>All women aged 18 to 55 undergoing laparoscopic or robot-assisted excision of lesions of the ovary, pelvic viscera, or peritoneal surface by a single surgeon from 2011 to 2022. Exclusion criteria included women who required emergent surgery, as well as those lacking surgical specimens submitted for pathological analysis or a documented preoperative pelvic examination.</p><p><strong>Interventions: </strong>A total of 209 clinical features, including demographics, presenting symptoms, gynecologic/obstetric history, and physical exam findings, were analyzed as predictors of endometriosis. The primary outcome was model performance in predicting endometriosis, evaluated using accuracy, sensitivity, specificity, and area under the receiver operating characteristic curve. Feature importance was assessed using Shapley Additive Explanation values.</p><p><strong>Results: </strong>Among 788 participants, 654 (83%) had pathology-confirmed endometriosis. The MLA, extreme gradient boosting, achieved an accuracy of 83%, sensitivity of 96%, and area under the receiver operating characteristic curve of 0.81. Shapley Additive Explanation analysis identified key predictors, including emesis (141 [21.56%] vs 10 [7.46%], p < .001), crampy pain (325 [49.69%] vs 38 [28.36%], p < .001), regular periods (429 [65.60%] vs 60 [44.78%], p < .001), severity of dysmenorrhea (0-3 Likert scale) (3 [1, 2] vs 3 [1, 2] p = .02), and retrocervical tenderness on rectovaginal exam (126 [19.27%] vs 7 [5.22%], p < .001).</p><p><strong>Conclusion: </strong>This study demonstrates that MLAs have potential to predict endometriosis preoperatively utilizing clinical features. Identified predictors, such as retrocervical tenderness, crampy pain, and regular periods, can aid primary care providers in early recognition and referral. Further validation in diverse populations is necessary to develop a widely applicable clinical prediction tool.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144120025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary Diffuse Large B-cell Lymphoma of Cervix in a Postmenopausal Woman.","authors":"Xuejian Li, Tianyi Wei, Boqiong Wu, Yu Chen","doi":"10.1016/j.jmig.2025.05.007","DOIUrl":"10.1016/j.jmig.2025.05.007","url":null,"abstract":"","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mary Katherine Anastasio MD , Allison Schwalb BS , Katherine Penvose BA , Donna Niedzwiecki PhD , Gloria Broadwater MS , Leah McNally MD
{"title":"Use of the Frailty “Timed Up and Go” Test to Predict Perioperative Complications in Patients Undergoing Gynecologic Cancer Surgery","authors":"Mary Katherine Anastasio MD , Allison Schwalb BS , Katherine Penvose BA , Donna Niedzwiecki PhD , Gloria Broadwater MS , Leah McNally MD","doi":"10.1016/j.jmig.2025.05.002","DOIUrl":"10.1016/j.jmig.2025.05.002","url":null,"abstract":"<div><h3>Study Objective</h3><div>To assess the predictive value of frailty measured by the timed up and go (TUG) test on perioperative outcomes versus other perioperative screening methods.</div></div><div><h3>Design</h3><div>Retrospective cohort study</div></div><div><h3>Setting</h3><div>Duke University Hospital and Duke Raleigh Hospital</div></div><div><h3>Patients</h3><div>Patients who underwent surgery with gynecologic oncologists at our institution from October 2019 to October 2023 with a preoperative TUG time recorded were included.</div></div><div><h3>Intervention(s)</h3><div>TUG times were recorded preoperatively. TUG time >12 seconds was considered frail. American Society of Anesthesiologists scores were extracted from the medical record. Modified frailty index (mFI) was calculated using 11 variables extracted from the medical record.</div></div><div><h3>Measurements and Main Results</h3><div>Outcomes included postoperative complications, length of stay, and postoperative disposition. Comparisons between TUG times dichotomized at 8 and 12 seconds were made using Wilcoxon rank sum or chi-square; logistic regression was used to predict TUG time using these dichotomizations.</div><div>Overall, 174 patients were included; 39 (22.4%) underwent laparotomy, 123 (70.6%) underwent laparoscopy, and 12 (6.9%) underwent other minor surgeries. Frail patients (TUG time > 12 seconds) were older and had higher mFI scores and lower preoperative albumin than nonfrail patients. There were no differences in major or minor complication rates after laparoscopic surgery between frail and nonfrail patients. American Society of Anesthesiologists and mFI were not associated with the need for transfusion (p > .05). Frail patients were more likely to receive a perioperative blood transfusion compared to nonfrail patients in the overall cohort (19.2% vs 4.1%, p = .0034). TUG time did not predict length of stay or postoperative disposition.</div></div><div><h3>Conclusion</h3><div>Slower TUG times were associated with comorbidities, older age, and malnutrition. Frailty was not associated with complications in those who underwent laparoscopic surgery. Our findings support the use of this easy-to-administer practical frailty screening tool compared to more traditional methods.</div></div>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":"32 8","pages":"Pages 731-738.e1"},"PeriodicalIF":3.5,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Large Prolapsed Submucous Leiomyoma Treated by Myomatous Twisting Followed by Hysteroscopic Pedicle Resection.","authors":"Yuanwei Liu, Wenchao Sun, Saiying Zhang","doi":"10.1016/j.jmig.2025.05.005","DOIUrl":"10.1016/j.jmig.2025.05.005","url":null,"abstract":"","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}