Tarek Khalife, Selim Afsar, Amy L Brien, Aakriti R Carrubba, Megan P Griffith, Katie Casper, Kristina A Butler, Sarah L Cohen Rassier
{"title":"Hysteroscopy-Guided Endometrial Sampling Diagnostic Performance in Endometrial Intraepithelial Neoplasia Patients.","authors":"Tarek Khalife, Selim Afsar, Amy L Brien, Aakriti R Carrubba, Megan P Griffith, Katie Casper, Kristina A Butler, Sarah L Cohen Rassier","doi":"10.1016/j.jmig.2025.03.021","DOIUrl":"https://doi.org/10.1016/j.jmig.2025.03.021","url":null,"abstract":"<p><strong>Objective: </strong>To compare the diagnostic performance of hysteroscopy-guided versus blind sampling in detecting concurrent endometrial carcinoma in patients with endometrial intraepithelial neoplasia and to identify factors associated with missing cancer diagnosis.</p><p><strong>Design: </strong>This is a retrospective cohort study.</p><p><strong>Setting: </strong>Integrated academic and community healthcare system in Minnesota and Wisconsin, USA, January 1, 2018, and January 1, 2023 PARTICIPANTS: This included 151 patients diagnosed with endometrial intraepithelial neoplasia during endometrial sampling who underwent a hysterectomy within three months. Patients with concurrent cancer diagnoses were excluded.</p><p><strong>Interventions: </strong>Patients diagnosed with endometrial intraepithelial neoplasia using hysteroscopy-directed biopsy were compared to those diagnosed with blind-sampling methods using the pathology results of the subsequent hysterectomy specimen as the gold standard comparator to analyze rates of missed endometrial cancer diagnosis.</p><p><strong>Measurements and main results: </strong>The primary outcome was a reduced risk of unanticipated concurrent endometrial cancer on the final hysterectomy pathology result for patients diagnosed with endometrial intraepithelial hyperplasia via a hysteroscopy-directed biopsy (OR=0.44, 95% CI=0.20-0.95, p = 0.033). In multivariate analysis, body mass index ≥30 and patient age >60 were associated with an elevated risk of endometrial cancer on final pathology (OR=4.17, 95% CI=1.51-11.51, p = 0.004; OR=5.56, 95% CI=1.22-35.21, p<0.001), respectively, and diabetes mellitus was the only independent variable associated with a higher risk of endometrial intraepithelial neoplasia on final hysterectomy pathology (OR=7.01, 95% CI=1.40-35.04, p = 0.018). Age, BMI, and endometrial thickness on pre-biopsy ultrasound were not associated with an increased risk of overlooking concurrent endometrial carcinoma on final hysterectomy pathology on univariate and multivariate analyses.</p><p><strong>Conclusion: </strong>Hysteroscopy-directed biopsy may reduce the risk of missing a concurrent endometrial malignancy during endometrial sampling in women with endometrial Intraepithelial neoplasia. The results affirm the superior diagnostic accuracy of hysteroscopy-directed endometrial evaluation.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Linder Diaz, Fernando Heredia, Belkys Zambrano, Harald Krentel
{"title":"Regarding \"Association between endometriosis and congenital uterine malformations: A single-center retrospective study.\"","authors":"Linder Diaz, Fernando Heredia, Belkys Zambrano, Harald Krentel","doi":"10.1016/j.jmig.2025.02.017","DOIUrl":"https://doi.org/10.1016/j.jmig.2025.02.017","url":null,"abstract":"<p><p>N/A.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Regarding \"A Comparative Study on the Efficacy of Subendometrial Versus Intrauterine Platelet-Rich Plasma Injections for Treating Intrauterine Adhesions: A Retrospective Cohort Study\".","authors":"Xuehong Zhu, Zhong Lin","doi":"10.1016/j.jmig.2025.03.020","DOIUrl":"https://doi.org/10.1016/j.jmig.2025.03.020","url":null,"abstract":"","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The AAGL's Role In Advancing Outpatient Surgery Worldwide had a Phoenix Connection. - The surgical instrument that helped shaped worldwide the delivery of surgical care.","authors":"Franklin D Loffer","doi":"10.1016/j.jmig.2025.03.013","DOIUrl":"https://doi.org/10.1016/j.jmig.2025.03.013","url":null,"abstract":"<p><p>The AAGL took the new concept of outpatient surgery which was occurring in the United States and introduced it to the world's surgical community.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical management of near complete labia majora fusion without hymenal disruption.","authors":"Houyu Yang, Yuanjunzi Shi, Gang Ji","doi":"10.1016/j.jmig.2025.03.009","DOIUrl":"https://doi.org/10.1016/j.jmig.2025.03.009","url":null,"abstract":"<p><p>The manuscript showcases images of a near-total fusion of a patient's labia majora. A 2-week therapy of estrogen was applied to resolve the adhesion, but it failed. Because the patient had a special requirement to keep her hymen intact, we performed surgical separation of the labia majora adhesion under hysteroscopic guidance. Subsequent 18-year follow-up confirmed the success of the surgery in achieving the expected normalization of the external genitalia. To the best of our knowledge, it is the first hysteroscopic application in major labial adhesion searching PubMed, and this technique's capacity to resolve extensive fibrous fusion without manipulating virginityrelated structures suggests endoscopic methods may address both anatomical and sociocultural needs in selected patients.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jin Wu, Yuanfang Ou, Yi Gu, Xiaofeng Zhou, Huiyu She, Yifan Qin
{"title":"Quadratus lumborum block for total laparoscopic hysterectomy: A systematic review and meta-analysis.","authors":"Jin Wu, Yuanfang Ou, Yi Gu, Xiaofeng Zhou, Huiyu She, Yifan Qin","doi":"10.1016/j.jmig.2025.03.012","DOIUrl":"https://doi.org/10.1016/j.jmig.2025.03.012","url":null,"abstract":"<p><strong>Objective: </strong>No regional blockade techniques are considered standard of care for total laparoscopic hysterectomy (TLH). Quadratus lumborum block (QLB), a novel fascial plane block, has emerged as a potential option; however, its analgesic efficacy in TLH remains unclear.</p><p><strong>Data sources: </strong>We conducted a comprehensive search across multiple databases, including Medline PubMed, Embase, the Cochrane Central Register of Controlled Trials, and Web of Science. No filters or language restrictions were imposed.</p><p><strong>Methods of study selection: </strong>The Population, Intervention, Comparison, and Outcomes framework in this review was as follows: (1) adult patients undergoing TLH; (2) QLB as the intervention; (3) comparison with no block or placebo; (4) primary outcome: 24-hour postoperative intravenous morphine-equivalent consumption; secondary outcomes: postoperative pain at 2, 4, 6, 12, and 24 hours, and the incidence of postoperative nausea and vomiting (PONV); (5) RCTs. Meta-analyses, including subgroup and sensitivity analyses, were conducted using a random-effects model.</p><p><strong>Tabulation, integration and results: </strong>This analysis included 8 trials with 540 patients. QLB significantly reduced postoperative 24-hour intravenous morphine-equivalent consumption following TLH [Mean Difference (MD): -4.61 mg; 95% CI: -7.13 to -2.09; p < 0.001; I² = 57%], though the reduction was below the minimal clinically important difference (MCID) of 10 mg. The static pain scores at 2, 6, and 12 hours, as well as dynamic pain scores at 2, 6, and 24 hours postoperatively, were significantly lower in the QLB group than in the control group. However, only the 2-hour postoperative dynamic pain score (MD = 1.19) exceeded the MCID of 1. No statistically significant differences were observed in the incidence of PONV.</p><p><strong>Conclusion: </strong>QLB statistically reduced postoperative opioid consumption and pain scores at certain time points after TLH, but only the 2-hour dynamic pain score exceeded the MCID with no improvement in PONV, suggesting limited clinical benefit of QLB in TLH.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patryk Piekos, Suset Rodriguez, Pasquale Patrizio, Jose Carugno
{"title":"Enhanced Myometrial Vascularity. A potentially serious complication after pregnancy loss. When to wait... when to intervene?","authors":"Patryk Piekos, Suset Rodriguez, Pasquale Patrizio, Jose Carugno","doi":"10.1016/j.jmig.2025.03.011","DOIUrl":"https://doi.org/10.1016/j.jmig.2025.03.011","url":null,"abstract":"","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brenna E Swift, Charlotte Axelrod, Anouk Benseler, Anna Kobylianskii, Danielle Vicus, Stephane Laframboise, Melissa Walker, Mara Sobel, Evan Tannenbaum
{"title":"A Multi-centre, Randomized Controlled Trial to Assess Video-based Surgical Coaching in Gynecology.","authors":"Brenna E Swift, Charlotte Axelrod, Anouk Benseler, Anna Kobylianskii, Danielle Vicus, Stephane Laframboise, Melissa Walker, Mara Sobel, Evan Tannenbaum","doi":"10.1016/j.jmig.2025.03.001","DOIUrl":"https://doi.org/10.1016/j.jmig.2025.03.001","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effect of video-based coaching on technical skill development in surgical education.</p><p><strong>Design: </strong>Randomized controlled trial with video-based coaching (intervention group) in addition to standard surgical curriculum or the standard surgical curriculum alone (control group).</p><p><strong>Setting: </strong>Laparoscopic vaginal vault closure in the operating room at three academic hospitals.</p><p><strong>Participants: </strong>Senior Obstetrics and Gynecology residents (year 3-5) on their chief resident or gynecologic oncology rotation.</p><p><strong>Interventions: </strong>All residents were recorded performing laparoscopic closure of the vaginal cuff prior to randomization. Surgical coaching sessions followed the Wisconsin Surgical Coaching Framework over 30 minutes on Zoom with one surgical coach. All residents were recorded subsequently performing the same surgical technical skill. Blinded, expert surgeons performed the video-assessment using the OSATS, GOALS and global rating scale. The mean change in operative time and the mean change in video-assessment score between the two video-recorded attempts was compared between groups. Qualitative semi-structured interviews were conducted to understand the residents' perspective on video-based surgical coaching.</p><p><strong>Results: </strong>Twenty residents participated with 10 in the coaching and 10 in the control group. Mean operative time to complete the suturing task was reduced by 32.8% (SD = 21.3%) in the coached group vs. 7.2% (SD = 25.1%) in the control group (p=.025). There was no significant change in surgical assessment scores within the coached or control group. Residents identified the core components of a surgical coaching program to include: (1) the resident: focused skill development, (2) the coach: focused on feedback (3) the coaching program: a structured activity. Residents envisioned monthly coaching with the opportunity for deliberate practice, the importance of a positive relationship between the coach and coachee, and the importance of faculty development in surgical coaching.</p><p><strong>Conclusion: </strong>Video-based surgical coaching is an effective tool to enhance technical skill development in surgical education.</p><p><strong>Data sharing: </strong>De-identified study data is available at Swift, Brenna (2024), \"Video-based Coaching in Gynecology\", Mendeley Data, V1, 10.17632/4h34g58kkn.1 https://data.mendeley.com/datasets/4h34g58kkn/1. This trial was registered with Clinicaltrials.gov ID: NCT05086783 on Sept 28, 2021 and can be found at https://clinicaltrials.gov/study/NCT05086783?term=NCT05086783&rank=1#study-record-dates.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anthony D Nguyen, Hannah L Marshall, Meg W Sidle, Veronica D Galaviz, Peter L Sticco, Keith T Downing
{"title":"Factors Associated with Spontaneous Conception Leading to Live Birth in Infertility Patients After Endometriosis Surgery.","authors":"Anthony D Nguyen, Hannah L Marshall, Meg W Sidle, Veronica D Galaviz, Peter L Sticco, Keith T Downing","doi":"10.1016/j.jmig.2025.03.010","DOIUrl":"https://doi.org/10.1016/j.jmig.2025.03.010","url":null,"abstract":"<p><strong>Study objective: </strong>To determine factors associated with spontaneous conception leading to live birth in infertility patients after endometriosis surgery.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Multi-hospital health system of Catholic Health in Long Island, NY.</p><p><strong>Participants: </strong>Infertility patients, between ages 18 and 45, who underwent endometriosis surgery with complete excision or ablation with or without excision and continued follow-up care for at least one year between January 1<sup>st</sup>, 2016 and March 31<sup>st</sup> 2022.</p><p><strong>Main results: </strong>Of the 100 patients, 50 achieved spontaneous conception and 40 achieved live birth within one year of surgery. Age less than 35 at the time of surgery was found to have an increased likelihood of live birth (RR 3.1, 95% CI 1.3-7.2). Being overweight (RR 1.0, 95% CI 0.4-2.2) or obese (RR 1.2, 95% CI 0.4-3.1) did not affect the likelihood of live birth. Surgery within 24 months of infertility diagnosis did not increase the likelihood of a successful delivery (RR 2.0, 95% CI 0.9-4.5). The pregnancy rate for AAGL Stage I, II, III, IV endometriosis were 42% (18/32), 32% (8/25), 46% (6/13), 42% (8/19) respectively. The logistic regression model indicated that live birth after spontaneous conception was significantly associated with younger age at the time of surgery and complete excision of endometriosis. Patients were 3.2 times (95% CI 1.3-7.8) more likely of having a live birth if they were less than 35 years old at the time of surgery. Complete excision of endometriosis conferred a 4.1-fold (95% CI 1.1-14.9) increased likelihood of a live birth.</p><p><strong>Conclusion: </strong>Two factors increased the likelihood of live birth after endometriosis surgery: age at the time of surgery and complete excision of endometriosis. We cautiously recommend patients attempting spontaneous conception find an endometriosis surgeon proficient in excisional techniques. If they are under 35, there may be additional benefit from surgery.</p>","PeriodicalId":16397,"journal":{"name":"Journal of minimally invasive gynecology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}