Journal of Medical Radiation Sciences最新文献

{"title":"Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non-small cell lung cancer: a scoping review","authors":"Carol Marks BSc,&nbsp;Michelle Leech PhD","doi":"10.1002/jmrs.831","DOIUrl":"10.1002/jmrs.831","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death. Definitive treatment includes chemotherapy and radiation therapy. Tumour hypoxia impacts the efficacy of these treatment modalities. Novel positron-emission tomography (PET) imaging has been developed to non-invasively quantify hypoxic tumour subregions, and to guide personalised treatment strategies. This review evaluates the reliability of hypoxia imaging in NSCLC in relation to various tracers, its correlations to treatment-related outcomes, and to assess if this imaging modality can be meaningfully applied into radiation therapy workflows.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A literature search was conducted on the Medline (Ovid) and Embase databases. Searches included terms related to ‘hypoxia’, ‘positron-emission tomography’, ‘magnetic resonance imaging’ and ‘lung cancer’. Results were filtered to exclude studies prior to 2011, and animal studies were excluded. Only studies referring to a confirmed pathology of NSCLC were included, while disease staging was not a limiting factor. Full-text English language and translated literature examined included clinical trials, clinical cohort studies and feasibility studies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Quantification of hypoxic volumes in a pre-treatment setting is of prognostic value, and indicative of treatment response. Dosimetric comparisons have highlighted potential to significantly dose escalate to hypoxic volumes without risk of additional toxicity. However, clinical data to support these strategies are lacking.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Heterogenous study design and non-standardised imaging parameters have led to a lack of clarity regarding the application of hypoxia PET imaging in NSCLC. PET imaging using nitroimidazole tracers is the most investigated method of non-invasively measuring tumour hypoxia and has potential to guide hypoxia-targeted radiation therapy. Further clinical research is required to elucidate the benefits versus risks of dose-escalation strategies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"72 1","pages":"106-118"},"PeriodicalIF":1.8,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.831","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrafraction motion and impact of margin reduction for MR-Linac online adaptive radiotherapy for pancreatic cancer treatments","authors":"Ashleigh Fasala BMRS(RT),&nbsp;Madeline Carr BMedRadPhysAdv (Hons), PhD,&nbsp;Yolanda Surjan PhD,&nbsp;Parmoun Daghigh MSc,&nbsp;Jeremy de Leon BSc (Bioinformatics), MBBS, FRANZCR,&nbsp;Abbey Burns BMRS(RT),&nbsp;Vikneswary Batumalai PhD","doi":"10.1002/jmrs.832","DOIUrl":"10.1002/jmrs.832","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Online adaptive radiotherapy is well suited for stereotactic ablative radiotherapy (SABR) in pancreatic cancer due to considerable intrafractional tumour motion. This study aimed to assess intrafraction motion and generate adjusted planning target volume (PTV) margins required for online adaptive radiotherapy in pancreatic cancer treatment using abdominal compression on the magnetic resonance linear accelerator (MR-Linac).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Motion monitoring images obtained from 67 fractions for 15 previously treated pancreatic cancer patients were analysed. All patients received SABR (50 Gy in five fractions) on the MR-Linac using abdominal compression. The analysis included quantification of intrafraction motion, leading to the development of adjusted PTV margins. The dosimetric impact of implementing the adjusted PTV was then evaluated in a cohort of 20 patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Intrafraction motion indicated an average target displacement of 1–3 mm, resulting in an adjusted PTV margin of 2 mm in the right–left and superior–inferior directions, and 3 mm in the anterior–posterior direction. Plans incorporating these adjusted margins consistently demonstrated improved dose to target volumes, with improvements averaging 1.5 Gy in CTV D99%, 4.9 Gy in PTV D99% and 1.2 Gy in PTV-high D90%, and better sparing of the organs at risk (OAR).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The improved target volume coverage and reduced OAR dose suggest potential for reducing current clinical margins for MR-Linac treatment. However, it is important to note that decreasing margins may reduce safeguards against geographical misses. Nonetheless, the continued integration of gating systems on MR-Linacs could provide confidence in adopting reduced margins.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"72 1","pages":"17-24"},"PeriodicalIF":1.8,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.832","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuing Professional Development - Medical Imaging","authors":"","doi":"10.1002/jmrs.829","DOIUrl":"10.1002/jmrs.829","url":null,"abstract":"<p>Maximise your continuing professional development (CPD) by reading the following selected article and answer the five questions. Please remember to self-claim your CPD and retain your supporting evidence. Answers will be available via the QR code and published in JMRS – Volume 72, Issue 4, December 2025.</p><p>Scan this QR code to find the answers.</p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"72 S2","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.829","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Open or closed: Experience of head and neck radiotherapy masks – A mixed-methods study","authors":"Erik Lundin MD,&nbsp;Sofia Axelsson PhD student,&nbsp;Emma Ohlsson-Nevo PhD","doi":"10.1002/jmrs.825","DOIUrl":"10.1002/jmrs.825","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>In radiotherapy for head and neck cancer, a mask is used to immobilise the head and shoulders. An open mask that does not cover the face is expected to cause less anxiety, but there is need to further investigate the patients' experience of open versus closed masks. Therefore, the aim of this study is to evaluate patient preferences for open or closed masks and whether an open mask can reduce discomfort and anxiety for patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twenty participants were treated in alternating weeks using open and closed masks. Their distress was evaluated through semi-structured interviews and patient-reported outcome measures.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>When using the open mask, it took longer to position the patient correctly. The closed mask felt more confining and could induce a sense of claustrophobia. Participants employed both internal and external strategies to cope with the stressful situation. The Hospital Anxiety and Depression Scale (HADS) showed a significant reduction in anxiety over time during the treatment period, but no significant difference between the masks. When participants chose which mask to use for the final treatments, 12 chose the open mask, while 8 chose the closed mask. In addition to the 20 analysed participants, two participants withdrew from the study because they could only tolerate the open mask, one due to anxiety and the other due to swelling.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The open mask seems to provide a less confined experience but may lead to greater difficulties in achieving the correct treatment position. While both masks can be viable options for most patients, some cannot tolerate closed masks but do tolerate open masks.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"72 1","pages":"74-84"},"PeriodicalIF":1.8,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.825","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142348406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuing Professional Development - Radiation Therapy","authors":"","doi":"10.1002/jmrs.826","DOIUrl":"10.1002/jmrs.826","url":null,"abstract":"<p>Maximise your CPD by reading the following selected article and answer the five questions. Please remember to self-claim your CPD and retain your supporting evidence. Answers will be available via the QR code and published in JMRS – Volume 72, Issue 4, December 2025.</p><p>Scan this QR code to find the answers.</p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 4","pages":"615"},"PeriodicalIF":1.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11638353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142289382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuing Professional Development - Medical Imaging","authors":"","doi":"10.1002/jmrs.827","DOIUrl":"10.1002/jmrs.827","url":null,"abstract":"<p>Maximise your CPD by reading the following selected article and answer the five questions. Please remember to self-claim your CPD and retain your supporting evidence. Answers will be available via the QR code and published in JMRS – Volume 72, Issue 4, December 2025.</p><p>Scan this QR code to find the answers.</p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 4","pages":"614"},"PeriodicalIF":1.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11638350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142289385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence and radiographer preliminary image evaluation: What might the future hold for radiographers providing x-ray interpretation in the acute setting?","authors":"Clare Rainey PhD, FHEA","doi":"10.1002/jmrs.821","DOIUrl":"10.1002/jmrs.821","url":null,"abstract":"<p>In a stretched healthcare system, radiographer preliminary image evaluation in the acute setting can be a means to optimise patient care by reducing error and increasing efficiencies in the patient journey. Radiographers have shown impressive accuracies in the provision of these initial evaluations, however, barriers such as a lack of confidence and increased workloads have been cited as a reason for radiographer reticence in engagement with this practice. With advances in Artificial Intelligence (AI) technology for assistance in clinical decision-making, and indication that this may increase confidence in diagnostic decision-making with reporting radiographers, the author of this editorial wonders what the impact of this technology might be on clinical decision-making by radiographers in the provision of Preliminary Image Evaluation (PIE).\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"71 4","pages":"495-498"},"PeriodicalIF":1.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11638352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142289381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Learning in radiation oncology: 12-month experience with a new incident learning system","authors":"Krystle Crouch BMedRadSc (RT), BHSc,&nbsp;Laura Adamson BSc, BApp SC RT (MRS),&nbsp;Rachael Beldham-Collins BAppSC RT (MRT), MHSc (Ed),&nbsp;Jonathan Sykes BA Phys (Hon), M MedPhys, PhD,&nbsp;David Thwaites MA, MSc, PhD, FIPEM FInstP, FACPSEM, FRCR (Hon)","doi":"10.1002/jmrs.823","DOIUrl":"10.1002/jmrs.823","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Safety and quality improvement are essential to clinical practice in radiation therapy as planning and treatment increase in complexity and sophistication. An incident learning system (ILS) is a safety and quality improvement tool that can aid risk mitigation to improve patient safety and quality of care. The aim of this study was to quantify the impact of implementing a new e-ILS, <b>L</b>earning <b>I</b>n <b>R</b>adiation <b>ON</b>cology (LIRON), on reporting and safety culture within a local health district (LHD).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The ILS (LIRON) was implemented in 2020 with the intent of tracking actual incidents, near misses and procedural non-compliances for analysis of root causes and contributing factors. A survey was conducted after 12 months of LIRON use, and distributed to radiation oncologists, radiation therapists and radiation oncology medical physicists within the LHD. Results were compared with the responses to a pre-ILS implementation survey, to review changes in staff perceptions of safety culture, barriers to reporting and ILS understanding.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Survey response rates were similar at baseline and at the 12-month follow-up, 64% and 63%, respectively. Findings showed increased ILS participation (49–71%), increased perception of no barriers to reporting (34–43%) and increased encouragement to report (37–43%). Greater confidence in the department's ability to learn from the ILS was evident (24–46%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Initial findings of LIRON implementation show positive impact but warrant further long-term review for greater understanding of its impact on staff perceptions, safety culture and improving departmental processes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"72 1","pages":"63-73"},"PeriodicalIF":1.8,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.823","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142289383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paediatric computed tomography diagnostic reference levels in Africa: A systematic review","authors":"Emmanuel Gyan Ph.D.,&nbsp;Christiana Subaar Ph.D.,&nbsp;George Edusei Ph.D.,&nbsp;Linda Antwi Nyarko MSc","doi":"10.1002/jmrs.824","DOIUrl":"10.1002/jmrs.824","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Improvements in computed tomography (CT) technology in terms of image quality and reduction in absorbed dose have increased its applications in medical imaging. Diagnostic reference levels (DRLs) help to identify high radiation doses that are unusually delivered to patients undergoing exposure to ionising radiation. The aim of this review was to provide an overview of published studies by African researchers towards establishing paediatric CT DRLs in Africa.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The search for articles was conducted using some relevant literature search engines including PubMed, Scopus, Science Direct, Google Scholar and Web of Science. Two reviewers were involved in the article selection process which involved a three-stage screening process of identifying; article titles, abstracts and full-test reading.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>One hundred and seventy-four articles were identified from the database, PubMed (30), Scopus (21), Google Scholar (53), Web of Science (25) and Science Direct (45). Fifty duplicated articles were excluded before screening. Twelve peer-reviewed articles were included in this study based on the inclusion criteria. DRL values in terms of computed tomography dose index volume of head for the age groupings 0–1, 1–5, 5–10 and 10–15 were 27, 36.6, 39.5 and 47.5 mGy while the dose length product values were 461.6, 664, 872 and 978 mGy.cm respectively. The DRLs were calculated as 75th percentile of the local DRLs reported by the 12 articles included in this review.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This review has shown that only few of the African countries (19%) have published studies on paediatric CT DRLs. There were variations in the DRLs published by the various authors which indicate that harmonisation and standardisation of paediatric CT protocols is essential for the optimisation of paediatric doses.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"72 1","pages":"139-147"},"PeriodicalIF":1.8,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.824","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142289384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiation therapists' perceptions of participating in Professional Supervision – a pilot study","authors":"Gay Dungey MEd,&nbsp;Sarah Thomson PGCert Professional Supervision, BHSc (MRT),&nbsp;Paula Rodriguez Lopez","doi":"10.1002/jmrs.822","DOIUrl":"10.1002/jmrs.822","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Professional Supervision (PS) is a common approach used to reduce the fallout from stress and burnout. It involves monthly face-to-face meetings between a supervisor and supervisee to address well-being and professional goals. This pilot study examines 12 radiation therapists (RTs) perceptions of participating in PS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Conducted in the Christchurch Radiation Oncology Centre, this mixed-methods pilot study introduced PS in March 2022. In August 2023, 12 RTs completed a QUALTRICS online questionnaire consisting of 33 questions, including the Supervisor Working Alliance Inventory (SWAI). The SWAI assessed the alliance of supervision from a supervisee's perspective and comprised of 19 questions on a 7-point Likert scale and nine yes/no statements with optional comments. Five demographic questions were also included.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All 12 RTs completed the questionnaire, with quantitative results indicating a positive alliance between supervisors and supervisees. RTs found PS to be a safe and comfortable space for reflective practice and support. Thematic analysis of qualitative data from additional comments revealed PS enabled RTs to reflect on career achievements, appreciate highlights of being an RT and consider future career paths within the profession.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Radiation therapists responded positively to PS, suggesting its potential in managing workplace stressors, promoting career advancement and providing dedicated time for reflection, support and guidance. RTs endorsed the efficacy of PS in enhancing their practice and advocated for its widespread adoption among RTs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16382,"journal":{"name":"Journal of Medical Radiation Sciences","volume":"72 1","pages":"54-62"},"PeriodicalIF":1.8,"publicationDate":"2024-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmrs.822","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142154373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}