Journal of interventional cardiology最新文献

{"title":"Rotational Atherectomy Combined With Super High-Pressure Noncompliant Balloon in Severe or Recurrent In-Stent Restenosis","authors":"Giacomo Maria Cioffi,&nbsp;Luca Vercelli,&nbsp;Duka Avdijaj,&nbsp;Mehdi Madanchi,&nbsp;Tobias Göldi,&nbsp;Adrian Attinger-Toller,&nbsp;Federico Moccetti,&nbsp;Mathias Wolfrum,&nbsp;Stefan Toggweiler,&nbsp;Matthias Bossard,&nbsp;Florim Cuculi","doi":"10.1155/joic/8869530","DOIUrl":"https://doi.org/10.1155/joic/8869530","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>In-stent restenosis (ISR) and recurrent ISR (Re-ISR) remain significant challenges of percutaneous coronary intervention (PCI), especially in complex lesions where conventional therapies are less effective. Rotational atherectomy (RA) combined with super high-pressure noncompliant (NC) balloons represents a potential strategy for addressing severe ISR or Re-ISR.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives and Methods</h3>\u0000 \u0000 <p>This study investigated the procedural success and safety as well as clinical outcomes of RA combined with super high-pressure NC balloons in patients with severe or Re-ISR. Consecutive patients treated for severe or Re-ISR between January 2020 and September 2024 were retrospectively analyzed. The primary endpoint was major adverse cardiovascular events (MACEs) at follow-up, including target vessel myocardial infarction (TV-MI), target lesion revascularization (TLR), and target vessel revascularization (TVR). Periprocedural complications were also recorded.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Out of 13 treated patients, 6 (46%) patients experienced periprocedural events, including 3 (23%) Type A dissections, 2 (15%) Type B dissections, and 1 (8%) Ellis Grade I perforation. 9 (70%) patients were treated with drug-coated balloons (DCBs), 1 (8%) of which had crossover to stenting and 2 (15%) had hybrid strategy with DCB and stenting combined. At a median follow-up of 13 months, 4 (31%) patients had MACE, comprising 1 (8%) TV-MI by TLR, 2 (15%) clinically driven TLR, and 1 (8%) TVR. Secondary outcomes included 1 (8%) case of hospitalization for heart failure (HF) and 1 (8%) COVID-19–related death.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>RA combined with super high-pressure NC balloons for the treatment of severe ISR or Re-ISR is associated with a significant risk of periprocedural complications. However, the midterm outcomes suggest this strategy might be effective in managing severe or Re-ISR.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trail Registration</h3>\u0000 \u0000 <p>ClinicalTrials.gov identifier: NCT06075602</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/8869530","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145572143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy Analysis of Percutaneous Endocardial Septal Radiofrequency Ablation Guided by Ablation Index in the Treatment of Drug-Resistant Hypertrophic Obstructive Cardiomyopathy","authors":"Haoruo Zhang,&nbsp;Songqing Yang,&nbsp;Geer Sheng,&nbsp;Chunlin Gong,&nbsp;Yuran Chen,&nbsp;Yuwen Huang,&nbsp;Siting Hong,&nbsp;Zhaojun Wang","doi":"10.1155/joic/6658568","DOIUrl":"https://doi.org/10.1155/joic/6658568","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Percutaneous endocardial septal radiofrequency ablation (PESA) is a novel interventional treatment for hypertrophic obstructive cardiomyopathy (HOCM). However, further research is required to confirm its safety and efficacy. Currently, there are no studies reporting the use of Ablation Index (AI) for energy guidance during PESA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 20 patients with drug-resistant HOCM were enrolled. All patients had previously received the maximum tolerated doses of beta-blockers and/or calcium channel blockers. All patients underwent PESA guided by AI with the assistance of intracardiac echocardiography. The primary efficacy endpoint was the change in left ventricular outflow tract gradient (LVOTG) from baseline to 1 month postoperation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean age of the patients was 55.75 ± 14.28 years, with an equal distribution of females and males. All patients completed a 1-month postoperative follow-up evaluation. Additionally, some patients underwent longer-term follow-up. The overall median follow-up duration was 94 days (IQR: 361.3 days). Regarding the primary efficacy endpoint, LVOTG significantly decreased to 44.15 ± 25.80 mmHg at 1 month postoperation (<i>p</i> &lt; 0.0001). As for secondary endpoints, LVOTG decreased from 68.75 ± 24.92 mmHg to 45.70 ± 26.55 mmHg (<i>p</i> = 0.0003), and the maximum interventricular septum thickness at end-diastole decreased from 19.77 ± 5.38 mm to 18.25 ± 5.41 mm (<i>p</i> = 0.0104). The average distance covered in the six-minute walk test increased from 180.00 ± 76.44 m to 317.50 ± 98.38 m (<i>p</i> &lt; 0.0001). Complete relief from chest pain symptoms was observed in 12 patients (60%, <i>p</i> &lt; 0.001), and 19 patients (95%) showed at least a one-class improvement in the New York Heart Association functional class (<i>p</i> &lt; 0.0001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study is the first to incorporate AI guidance into PESA, demonstrating that this approach offers favorable safety and efficacy in the treatment of drug-resistant HOCM. It effectively reduces left ventricular outflow tract obstruction and alleviates chest pain symptoms.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/6658568","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145572468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary Steal Syndrome due to a Side Branch of the LIMA in Patients Undergoing Coronary Artery Bypass Grafting","authors":"Adrien Jossart,&nbsp;Giuseppe Colletti,&nbsp;Silviu Dumitrascu,&nbsp;Agostino Spano,&nbsp;Laura Peter,&nbsp;Quentin Trefois,&nbsp;Elias Bentakhou,&nbsp;Manuel Mignon,&nbsp;Claudiu Ungureanu","doi":"10.1155/joic/3688095","DOIUrl":"https://doi.org/10.1155/joic/3688095","url":null,"abstract":"<p>Coronary steal syndrome (CSS) is a rare but potentially serious phenomenon that can occur after coronary artery bypass grafting (CABG), where the presence of a patent large collateral arterial branch may decrease flow through the main graft toward the myocardium. This condition can result in functional incomplete revascularization and reduce the benefit of the surgical intervention. The diagnosis and management of CSS pose significant challenges, which are described in this article through three clinical cases, accompanied by a review of existent medical data regarding this rare pathology.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/3688095","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145406557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of vFFR and FFR Wire: Data From the Réunion Registry","authors":"Christophe Pouillot,&nbsp;Stephane Fournier,&nbsp;Jens Glasenapp,&nbsp;Karim Bougrini,&nbsp;Richard Vi Fane,&nbsp;Yassine Gadri,&nbsp;Geoffray Rambaud,&nbsp;David Huchette,&nbsp;Adil Salihu","doi":"10.1155/joic/9624166","DOIUrl":"https://doi.org/10.1155/joic/9624166","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Assessing fractional flow reserve (FFR) with a pressure wire is frequently underused due to the invasiveness of guide wire insertion and the necessity for a hyperemic agent. This study aimed to assess the diagnostic accuracy of the CAAS-vessel FFR (vFFR) software tool compared to pressure wire (pw) FFR in evaluating coronary stenotic lesions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A single-center, prospective study was conducted at Clinique Saint Clotilde, Reunion Island, from August 2023 to March 2024. All patients undergoing coronary angiograms with pwFFR assessment of lesion severity of 40%–70% were included. Diagnostic accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of vFFR were calculated using pwFFR as the reference standard. The cutoff value of 0.80 was used for both modalities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 116 patients with 146 lesions were included. The mean age was 67 ± 9 years old, with 19% being female. Patients had an average of 1.3 ± 0.4 lesions each, with a mean pwFFR of 0.79 ± 0.09 and a mean vFFR of 0.79 ± 0.28. The overall diagnostic accuracy of vFFR was 77%, with sensitivity/specificity of 85%/71% and PPV/NPV of 67%/87%. For the left anterior descending coronary artery, the accuracy was 78%, with a sensitivity/specificity of 81%/78%. In the grey zone (invasive FFR 0.75–0.85), the accuracy dropped to 70%.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>vFFR is a reliable noninvasive alternative to pwFFR, showing acceptable diagnostic accuracy in line with current literature.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/9624166","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145366684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Pulmonary Vein Ostium Morphology on Outcomes of Second-Generation Cryoablation for Paroxysmal Atrial Fibrillation: Procedural Characteristics and Long-Term Recurrence","authors":"Liang Feng,&nbsp;Qian Hou,&nbsp;Zhenglong Xue,&nbsp;Huixin Zheng,&nbsp;Jinglan Wu,&nbsp;Ling You,&nbsp;Ruiqin Xie","doi":"10.1155/joic/3689976","DOIUrl":"https://doi.org/10.1155/joic/3689976","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Cryoballoon ablation (CbA) for pulmonary vein isolation (PVI) is increasingly used in the treatment of paroxysmal atrial fibrillation (PAF). We aimed to assess the relationship between pulmonary vein ostium (PVO) morphology and procedural outcomes after CbA for PAF.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 463 patients with PAF were enrolled. PVO morphology was evaluated using preprocedural computed tomography (CT). Intraoperative cryoablation parameters and adverse events were recorded. Patients were followed up for at least 1 year.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The superior PVs exhibited the longest long-axis diameter at PVO (left, 21.85 ± 3.22 mm; right, 21.55 ± 3.71 mm, all <i>p</i> &lt; 0.05), while the right superior PVs had the largest short-axis diameter (18.46 ± 3.56 mm, all <i>p</i> &lt; 0.05). The left superior PVO showed the greatest ellipticity (difference between long-axis and short-axis diameters: 6.60 ± 3.35 mm, all <i>p</i> &lt; 0.05), whereas the right superior PVO had the largest mean diameter (20.00 ± 3.42 mm, all <i>p</i> &lt; 0.05). Left-sided PVOs demonstrated the highest ellipticity. The size of the left superior PVO was negatively correlated with the nadir freezing temperature and positively correlated with rewarming time (both <i>p</i> &lt; 0.05). The long-axis diameter of PVO was positively associated with the additional radiofrequency ablation (<i>p</i> &lt; 0.05). Multivariate analysis identified left superior PVO morphology as an independent predictor of late recurrence (<i>β</i> = 2.703, <i>p</i> = 0.010).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Large PVO dimensions, particularly in the left superior PV, are associated with intraoperative difficulty during second-generation CbA for PAF. Additionally, left superior PVO ellipticity predicts late recurrence. Preprocedural PV CT imaging may be valuable for a quick clinical predict for PAF.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/3689976","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145317354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Impact of Intraoperative Temperature Strategy in CABG: A Normothermic Advantage","authors":"Maryam Bahramian,&nbsp;Mozhgan Bahramian,&nbsp;Ahmad Amouzeshi,&nbsp;Mohammad Esmatinia,&nbsp;Ali Bonyad","doi":"10.1155/joic/1666151","DOIUrl":"https://doi.org/10.1155/joic/1666151","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The optimal temperature strategy during cardiopulmonary bypass (CPB) for coronary artery bypass grafting (CABG) remains debated. We compared perioperative outcomes between normothermic and hypothermic CPB in a single-center cohort in Iran.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective cohort of 98 consecutive adults were undergoing isolated, on-pump CABG at Razi Hospital (March 2020–March 2021). Patients were grouped by intraoperative temperature strategy (normothermia 35°C–37°C without topical cooling vs. hypothermia 28°C–32°C with topical cooling as used). Data were abstracted from charts using a predefined checklist (demographics/comorbidities, operative details, intra-/postoperative transfusion and fluid balance, electrolytes/renal indices, complete blood count, ICU/ward length of stay, 12 h core temperature, mortality, and neurological events). Two-sided tests were used with <i>α</i> = 0.05.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Groups were balanced in baseline characteristics. Compared to normothermia, hypothermia required more intraoperative packed cells (mean: 476 vs. 191 mL; <i>p</i> &lt; 0.001), while postoperative transfusion until discharge was similar (636 vs. 560 mL; <i>p</i> = 0.42). ICU (2.2 vs. 1.9 days; <i>p</i> &lt; 0.001) and ward stay (5.4 vs. 3.8 days; <i>p</i> &lt; 0.001) were longer with hypothermia. Postoperative sodium increased in normothermia (<i>p</i> &lt; 0.001) but not in hypothermia (<i>p</i> = 0.173); both groups showed increased urea/creatinine and decreased RBC/Hb/Hct postoperatively. Serum intake and urine output were higher intra- and postoperatively in hypothermia (all <i>p</i> &lt; 0.001). Ejection fraction and 12-h core temperature did not differ; mortality and CVA were rare and comparable.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In this cohort, normothermic CPB for isolated CABG was associated with fewer intraoperative transfusions and shorter ICU/ward stays than hypothermia, with otherwise similar short-term safety signals. Prospective studies should test long-term and patient-reported outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/1666151","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145223843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Value of GRACE Score and Left Ventricular Ejection Fraction in Non-ST-Segment Elevation Myocardial Infarction","authors":"Yong Hoon Kim,&nbsp;Ae-Young Her,&nbsp;Seung-Woon Rha,&nbsp;Cheol Ung Choi,&nbsp;Byoung Geol Choi,&nbsp;Soohyung Park,&nbsp;Jung Rae Cho,&nbsp;Min-Woong Kim,&nbsp;Ji Young Park,&nbsp;Myung Ho Jeong","doi":"10.1155/joic/3838955","DOIUrl":"https://doi.org/10.1155/joic/3838955","url":null,"abstract":"<p><b>Background:</b> To provide more useful information due to the lack of published results to date, we analyzed the 3-year clinical outcomes of patients with non-ST-segment elevation myocardial infarction (NSTEMI) using the Global Registry of Acute Coronary Events (GRACE) score and the degree of left ventricular ejection fraction (LVEF).</p><p><b>Methods:</b> In total, 4558 patients were stratified into two groups: GRACE score &gt; 140 (group A) and GRACE score ≤ 140 (Group B). Each group was further subdivided into heart failure (HF) with reduced EF (HFrEF), HF with mildly reduced EF (HFmrEF), and HF with preserved EF (HFpEF). The primary outcome was all-cause mortality, and the secondary outcomes were cardiac death (CD), non-CD, recurrent MI, and hospitalization for HF (HHF).</p><p><b>Results:</b> After adjustment, in Group A, the 3-year rates of all-cause mortality (<i>p</i> &lt; 0.001 for all), CD, and HHF were higher in the HFrEF subgroup than in the HFmrEF and HFpEF subgroups, with similar outcomes between the HFmrEF and HFpEF subgroups. In Group B, the HFrEF subgroup had higher CD (<i>p</i> = 0.019) and HHF rates than did the HFmrEF subgroup and higher all-cause mortality (<i>p</i> = 0.001), CD (<i>p</i> &lt; 0.001), and HHF rates than the HFpEF subgroup. All-cause mortality rate between the HFrEF and HFmrEF subgroups was similar, whereas the HFmrEF subgroup had a higher all-cause mortality rate than did the HFpEF subgroup (<i>p</i> = 0.022). Group A had worse clinical outcomes than Group B across all LVEF subgroups.</p><p><b>Conclusion:</b> Although the HFrEF subgroup had a higher all-cause mortality rate than did the HFpEF subgroup, all-cause mortality patterns between the HFrEF and HFmrEF subgroups and between the HFmrEF and HFpEF subgroups varied according to the GRACE score. However, broader studies with a larger number of patients are needed.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/3838955","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping the Evolution of Drug-Coated Balloon Research in Coronary Artery Disease: A 2006–2023 Bibliometric and Visual Analysis","authors":"Jiayang Dong,&nbsp;Zhiqiang Zhang,&nbsp;Jiayi Sun,&nbsp;Xinyue Yang,&nbsp;Wenjuan Zhang","doi":"10.1155/joic/1837323","DOIUrl":"https://doi.org/10.1155/joic/1837323","url":null,"abstract":"<p><b>Background:</b> Drug-coated balloons (DCBs) have emerged as an innovative technology for coronary artery disease treatment. However, bibliometric research on DCB development trends is still lacking.</p><p><b>Methods:</b> We performed a bibliometric analysis of DCB-related publications from 2006 to 2023, extracted from the Web of Science Core Collection database. Analysis dimensions included temporal publication patterns, distributions of countries/regions and institutions, author and journal productivity/impact, keyword co-occurrence and bursts, collaboration networks, and seminal studies. Visualization tools such as the R package “Bibliometrix,” VOSviewer, and CiteSpace facilitated the graphical mapping of research hotspots.</p><p><b>Result:</b> This bibliometric analysis of 781 DCB-related publications shows an increasing annual output since 2011, exceeding 100 in 2021. Germany, China, Italy, Japan, and the United States were dominant in DCB research, with Germany accruing the highest citation count of 6477. The Technical University of Munich published the most DCB-related papers (<i>n</i> = 22). Bruno Scheller had the highest author productivity (<i>n</i> = 45) and citations (<i>n</i> = 3235). Analyses of keyword co-occurrence showed prevalent foci encompassing “DCB,” “drug-eluting stent,” and “in-stent restenosis.” Newly emerging topics contain “DCB-only strategy” and intravascular imaging.</p><p><b>Conclusion:</b> The research activities on DCB have greatly expanded, with significant advancements in device design and indications. Recent priorities signal a shift towards physiology/intravascular imaging–guided usage and DCB as standalone therapies for more de novo coronary lesions. Ongoing advances will consolidate DCB in guidelines and daily practice. Our analysis provides strategic insights, informing research and clinical directions.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/1837323","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145062702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Instantaneous Wave-Free Ratio-Guided Interventions in Side Branches Improve Results in Bifurcation Lesions Compared to Conventional Techniques","authors":"Zia-ul-Sabah,&nbsp;Adel Masswary,&nbsp;Mohammed Alahmari,&nbsp;Abdullah Asiri,&nbsp;Javed Iqbal Wani,&nbsp;Humayoun Durrani,&nbsp;Shahid Aziz,&nbsp;Hafed Ahmad Alaskary,&nbsp;Ali Alqarni,&nbsp;Ayyub Ali Patel","doi":"10.1155/joic/1482690","DOIUrl":"https://doi.org/10.1155/joic/1482690","url":null,"abstract":"<p><b>Background:</b> In coronary lesions characterized by bifurcation anatomies, provisional side-branch intervention is the preferred treatment approach. However, there is a well-documented discrepancy between angiographic evaluations of blood flow obstruction and the actual functional severity of bifurcation lesions. Additionally, the use of fractional flow reserve (FFR) carries notable side effects primarily associated with the necessity of adenosine administration. Given the demonstrated noninferiority of the instantaneous wave-free ratio (iFR) compared to FFR, this study aimed to assess the clinical and functional benefits of iFR-guided side-branch ballooning which involving drug-eluting balloon inflation in side branch in comparison to conventional intervention techniques for bifurcation lesions.</p><p><b>Methods:</b> In this prospective cohort study, a total of 100 patients with coronary lesions characterized by bifurcation anatomies were enrolled and randomly assigned to two groups: the iFR-based intervention group, which utilized only side-branch intervention involving drug-eluting balloon inflation, and the conventional intervention group. Both groups were monitored for 12 months postintervention to assess various clinical and functional endpoints.</p><p><b>Results:</b> In the iFR-guided group, only 2 patients (4%) met the primary endpoint (a composite of target bifurcation-related nonfatal myocardial infarction, target bifurcation revascularization, and any unplanned revascularization) compared to 10 patients (20%) in the conventional group (<i>p</i> = 0.01). The study also demonstrated the superiority of iFR-guided drug-eluting balloon inflation in side branches over conventional interventional procedures for bifurcation lesions, as evidenced by a reduction in fluoroscopy time (mean difference [MD] = −8.9 min, 95% confidence interval [CI] = −15.6 to −2.1, <i>p</i> = 0.01), intervention duration (MD = −11.6 min, 95% CI = −20.5 to −2.8, <i>p</i> = 0.01), and length of hospital stay (MD = −1 day, 95% CI = −1.2 to −0.80, <i>p</i> &lt; 0.0001). Additionally, the amount of contrast media used in the iFR-guided intervention group was significantly lower than that in the conventional treatment group (<i>p</i> &lt; 0.0001).</p><p><b>Conclusions:</b> iFR-guided side-branch intervention involving drug-eluting balloon inflation in bifurcation lesions was significantly better when compared to conventional interventions in terms of clinical and functional outcomes in patients with coronary lesions characterized by bifurcation anatomies.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/1482690","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preprocedural Risk Factors of In-Hospital Mortality Following Percutaneous Coronary Intervention: A Systematic Review of Risk-Adjustment Models","authors":"Mohammad Rocky Khan Chowdhury,&nbsp;Dion Stub,&nbsp;Diem Dinh,&nbsp;Hasina Akhter Chowdhury,&nbsp;Baki Billah,&nbsp;Md. Nazmul Karim","doi":"10.1155/joic/8760459","DOIUrl":"https://doi.org/10.1155/joic/8760459","url":null,"abstract":"<p>Assessing the preprocedural risk of mortality following percutaneous coronary intervention (PCI) is crucial for clinical decision-making, quality registries, and performance monitoring. This systematic review aims to summarize preprocedural factors associated with in-hospital mortality post-PCI. A systematic search of MEDLINE, EMBASE, CINAHL, and Web of Science was conducted up to April 2024, without language restrictions, to identify preprocedural factors associated with in-hospital mortality post-PCI. The information was systematically evaluated and descriptively summarized following the CHhecklist for critical Appraisal and data extraction for systematic Reviews of prediction Modeling Studies (CHARMS) checklist. The search initially identified 9552 studies, with 28 articles ultimately included in the final analysis. The pooled prevalence of in-hospital mortality post-PCI was 1.63%, whereas it was 6.40% for patients with acute coronary syndrome (ACS). A total of 77 independent preprocedural factors were found to be significantly associated with in-hospital mortality, of which 22 were consistently reported across multiple studies and identified as potential key factors. Factors most frequently reported in various studies included, but not limited to, ACS (<i>n</i> = 27, 96.4%), renal failure (<i>n</i> = 24, 85.7%), age (<i>n</i> = 19, 67.9%), gender (<i>n</i> = 16, 57.1%), cardiac events (<i>n</i> = 15, 53.6%), ejection fraction (<i>n</i> = 15, 53.6%), vascular disease (<i>n</i> = 12, 42.9%), heart failure (<i>n</i> = 12, 42.9%), body mass index (<i>n</i> = 10, 35.7%), lesion location (<i>n</i> = 9, 32.1%), diabetes (<i>n</i> = 8, 28.6%), and vessel disease (<i>n</i> = 8, 28.6%). Eleven articles (39.2%) used imputation methods to handle missing data. Logistic regression was used by 19 articles (67.9%), and five articles (18.6%) used the machine learning (ML) method. Nineteen articles (67.9%) reported the discriminatory performance of the models using receiver operating characteristic (ROC) score ranging from 0.776 to 0.960. Incorporating the 22 preprocedural factors identified in this study can aid clinicians in decision-making for high-risk cases. To improve risk adjustment models, these factors should be integrated, missing data carefully managed, models validated, and ML techniques utilized.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/8760459","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144923461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}