{"title":"心脏磁共振体素内非相干运动技术评价肥厚性心肌病微循环功能障碍的价值。","authors":"Alina Abulaiti, Quan Zhang, Haiyan Huang, Shuang Ding, Miriguli Shayiti, Shaoyu Wang, Yunling Wang, Wenxiao Jia","doi":"10.1155/2023/4611602","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the value of the cardiac magnetic resonance intravoxel incoherent motion (IVIM) technique in microcirculatory dysfunction in patients with hypertrophic cardiomyopathy (HCM).</p><p><strong>Methods: </strong>The medical records of 19 patients with HCM in our hospital from January 2020 to May 2021 were collected retrospectively, and 23 healthy people with a similar age and gender distribution to the patients with HCM were included as controls. All the included subjects underwent clinical assessment and cardiac magnetic resonance imaging. The original IVIM images were analysed, and the imaging parameters of each segment were measured. The HCM group was divided into non-hypertrophic myocardium and hypertrophic myocardium groups. The differences in imaging parameters between the normal and HCM groups were compared. A Spearman correlation analysis was used to explore the correlation between end-diastolic thickness (EDTH) and each IVIM parameter.</p><p><strong>Results: </strong>The D<sup><i>∗</i></sup> and f values in the HCM group were lower than those in the normal group (<i>p</i> < 0.0001 and <i>p</i> = 0.004, respectively). The f, D, D<sup><i>∗</i></sup>, and EDTH values of the hypertrophic segment, non-hypertrophic segment, and normal groups were statistically significant (<i>p</i> < 0.05). The difference in D<sup><i>∗</i></sup> values among the mild, moderate, severe, and very severe HCM groups was statistically significant (<i>p</i> < 0.05). There was a statistically significant difference in EDTH among the mild, moderate, severe, and very severe groups (<i>p</i> < 0.001). There were significant differences in the values of D, D<sup><i>∗</i></sup>, and f between the non-delayed enhancement group and the delayed enhancement group (<i>p</i> < 0.05). The EDTH values of 304 segments in the HCM group were negatively correlated with f (<i>r</i> = -0.219, <i>p</i> = 0.028) and D<sup><i>∗</i></sup> values (<i>r</i> = -0.310, <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>The use of IVIM technology can achieve a non-invasive early quantitative assessment of microvascular disease in HCM without the injection of a contrast agent and provide a reference for the early diagnosis of and intervention in myocardial ischemia in patients with HCM.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2023 ","pages":"4611602"},"PeriodicalIF":1.6000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322278/pdf/","citationCount":"0","resultStr":"{\"title\":\"The Value of the Cardiac Magnetic Resonance Intravoxel Incoherent Motion Technique in Evaluating Microcirculatory Dysfunction in Hypertrophic Cardiomyopathy.\",\"authors\":\"Alina Abulaiti, Quan Zhang, Haiyan Huang, Shuang Ding, Miriguli Shayiti, Shaoyu Wang, Yunling Wang, Wenxiao Jia\",\"doi\":\"10.1155/2023/4611602\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To evaluate the value of the cardiac magnetic resonance intravoxel incoherent motion (IVIM) technique in microcirculatory dysfunction in patients with hypertrophic cardiomyopathy (HCM).</p><p><strong>Methods: </strong>The medical records of 19 patients with HCM in our hospital from January 2020 to May 2021 were collected retrospectively, and 23 healthy people with a similar age and gender distribution to the patients with HCM were included as controls. All the included subjects underwent clinical assessment and cardiac magnetic resonance imaging. The original IVIM images were analysed, and the imaging parameters of each segment were measured. The HCM group was divided into non-hypertrophic myocardium and hypertrophic myocardium groups. The differences in imaging parameters between the normal and HCM groups were compared. A Spearman correlation analysis was used to explore the correlation between end-diastolic thickness (EDTH) and each IVIM parameter.</p><p><strong>Results: </strong>The D<sup><i>∗</i></sup> and f values in the HCM group were lower than those in the normal group (<i>p</i> < 0.0001 and <i>p</i> = 0.004, respectively). The f, D, D<sup><i>∗</i></sup>, and EDTH values of the hypertrophic segment, non-hypertrophic segment, and normal groups were statistically significant (<i>p</i> < 0.05). The difference in D<sup><i>∗</i></sup> values among the mild, moderate, severe, and very severe HCM groups was statistically significant (<i>p</i> < 0.05). There was a statistically significant difference in EDTH among the mild, moderate, severe, and very severe groups (<i>p</i> < 0.001). There were significant differences in the values of D, D<sup><i>∗</i></sup>, and f between the non-delayed enhancement group and the delayed enhancement group (<i>p</i> < 0.05). The EDTH values of 304 segments in the HCM group were negatively correlated with f (<i>r</i> = -0.219, <i>p</i> = 0.028) and D<sup><i>∗</i></sup> values (<i>r</i> = -0.310, <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>The use of IVIM technology can achieve a non-invasive early quantitative assessment of microvascular disease in HCM without the injection of a contrast agent and provide a reference for the early diagnosis of and intervention in myocardial ischemia in patients with HCM.</p>\",\"PeriodicalId\":16329,\"journal\":{\"name\":\"Journal of interventional cardiology\",\"volume\":\"2023 \",\"pages\":\"4611602\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10322278/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of interventional cardiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1155/2023/4611602\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of interventional cardiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1155/2023/4611602","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
The Value of the Cardiac Magnetic Resonance Intravoxel Incoherent Motion Technique in Evaluating Microcirculatory Dysfunction in Hypertrophic Cardiomyopathy.
Objective: To evaluate the value of the cardiac magnetic resonance intravoxel incoherent motion (IVIM) technique in microcirculatory dysfunction in patients with hypertrophic cardiomyopathy (HCM).
Methods: The medical records of 19 patients with HCM in our hospital from January 2020 to May 2021 were collected retrospectively, and 23 healthy people with a similar age and gender distribution to the patients with HCM were included as controls. All the included subjects underwent clinical assessment and cardiac magnetic resonance imaging. The original IVIM images were analysed, and the imaging parameters of each segment were measured. The HCM group was divided into non-hypertrophic myocardium and hypertrophic myocardium groups. The differences in imaging parameters between the normal and HCM groups were compared. A Spearman correlation analysis was used to explore the correlation between end-diastolic thickness (EDTH) and each IVIM parameter.
Results: The D∗ and f values in the HCM group were lower than those in the normal group (p < 0.0001 and p = 0.004, respectively). The f, D, D∗, and EDTH values of the hypertrophic segment, non-hypertrophic segment, and normal groups were statistically significant (p < 0.05). The difference in D∗ values among the mild, moderate, severe, and very severe HCM groups was statistically significant (p < 0.05). There was a statistically significant difference in EDTH among the mild, moderate, severe, and very severe groups (p < 0.001). There were significant differences in the values of D, D∗, and f between the non-delayed enhancement group and the delayed enhancement group (p < 0.05). The EDTH values of 304 segments in the HCM group were negatively correlated with f (r = -0.219, p = 0.028) and D∗ values (r = -0.310, p < 0.001).
Conclusion: The use of IVIM technology can achieve a non-invasive early quantitative assessment of microvascular disease in HCM without the injection of a contrast agent and provide a reference for the early diagnosis of and intervention in myocardial ischemia in patients with HCM.
期刊介绍：
Journal of Interventional Cardiology is a peer-reviewed, Open Access journal that provides a forum for cardiologists determined to stay current in the diagnosis, investigation, and management of patients with cardiovascular disease and its associated complications. The journal publishes original research articles, review articles, and clinical studies focusing on new procedures and techniques in all major subject areas in the field, including:
Acute coronary syndrome
Coronary disease
Congenital heart diseases
Myocardial infarction
Peripheral arterial disease
Valvular heart disease
Cardiac hemodynamics and physiology
Haemostasis and thrombosis
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