Journal of interventional cardiology最新文献

{"title":"Medium-to-Long-Term Outcomes of Tricuspid Regurgitation After Transcatheter Closure of Ventricular Septal Defect in Children","authors":"Zihan Tang,&nbsp;Xin Li,&nbsp;Xingyue Pu,&nbsp;Haiyi Xia,&nbsp;Yi Wei,&nbsp;Jianjun Su,&nbsp;Shenglin Yang,&nbsp;Fengchuan Jing,&nbsp;Qijian Yi","doi":"10.1155/joic/3743598","DOIUrl":"https://doi.org/10.1155/joic/3743598","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>Transcatheter closure of ventricular septal defect (VSD) is an effective treatment for children. However, the changes in tricuspid regurgitation (TR) after the closure remain unclear. This study aimed to assess the fate of TR after transcatheter VSD closure.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The patients were categorized into a none/mild preoperative TR group and a moderate/severe preoperative TR group. Changes in TR severity postprocedure were evaluated, and risk factors for persistent TR were identified.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 942 children were enrolled, comprising 892 with none/mild TR and 50 with moderate/severe TR. The median follow-up time was 22.4 months (range 6–109 months). Among the 50 children with preoperative moderate/severe TR, 36 cases (72%) demonstrated significant improvement in TR, whereas 14 cases (28%) maintained persistent TR after closure. Of the 892 children with preoperative none/mild TR, 28 cases (2.9%) developed postoperative persistent TR (24 moderate and 4 severe). Among these 28 cases, 6 were new onset, and the remainder all resulted from progression. 73% of postoperative severe TR cases occurred within the first 24 hours after closure. A VSD located behind the tricuspid septal leaflet and occluder size/VSD right ventricular size ≥ 2.5 were identified as risk factors for postoperative persistent TR.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>TR in children with VSD is common and typically mild, both before and after closure. A larger ratio of occluder size to VSD right ventricular size, along with a defect located behind the tricuspid septal leaflet, increases the risk of persistent TR. Long-term follow-up is crucial for detecting potential TR progression.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2026 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/3743598","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective Single-Center Study of the Nano-Crush Technique for De Novo True Coronary Bifurcation Lesions","authors":"Shuvanan Ray,&nbsp;Siddhartha Bandyopadhay,&nbsp;Priyam Mukherjee,&nbsp;Suman Karmakar,&nbsp;Pallab Kumar Bose,&nbsp;Basasendra Chowdhury,&nbsp;Avik Karak,&nbsp;Arindom Mondal,&nbsp;Deepankar Paul","doi":"10.1155/joic/6226181","DOIUrl":"https://doi.org/10.1155/joic/6226181","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Coronary artery disease remains a major global health burden. In complex bifurcation lesions, percutaneous coronary intervention (PCI) is preferred when medical therapy is insufficient. The Nano-Crush technique, a refined two-stent approach, offers improved side-branch ostial coverage with minimal metal overlap and procedural complexity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This single-center, observational study was conducted to evaluate the procedural outcomes and safety of the Nano-Crush technique in patients undergoing PCI for de novo coronary bifurcation lesions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Fifty patients with true bifurcation lesions (Medina classification 1.1.1, 0.1.1, or 1.0.1, proximal vessel diameter ≥ 3 mm, and side branch diameter ≥ 2.5 mm) were treated using the Nano-Crush technique with sirolimus-eluting stents. The primary endpoint was target vessel failure (TVF) before discharge and at 12 months. Secondary endpoints included procedural success, complication rates, cardiac biomarkers, and safety evaluation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean age was 63.1 ± 11.5 years, with 90% men. All patients achieved procedural success (final diameter stenosis of &lt; 30% and TIMI Grade 3 flow in both main and side branch vessels) without any periprocedural complications. All patients remained alive and clinically stable at 12 months. Postprocedural troponin increased nonsignificantly (<i>p</i> = 0.303), while creatine kinase-myocardial band isoenzyme increased significantly (<i>p</i> &lt; 0.001). SYNTAX scores declined significantly from a median of 16 (8–23) to 3 (2–6) post-PCI (<i>p</i> &lt; 0.001). Four patients experienced mild chest pain at 6 months, managed conservatively. No TVF, target lesion failure, or stent thrombosis occurred at 6 or 12 months.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The Nano-Crush technique was associated with encouraging procedural and clinical observations in this selected cohort with true coronary bifurcation lesions. These descriptive findings require validation in larger comparative studies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2026 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/6226181","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149146046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction and Validation of a Predictive Nomogram for Target Lesion Revascularization After Drug-Coated Balloon Angioplasty in Coronary Artery Disease","authors":"Zhihao Zhao,&nbsp;Lin Bo,&nbsp;Yu Yang,&nbsp;Fengyun Zhang","doi":"10.1155/joic/4408092","DOIUrl":"https://doi.org/10.1155/joic/4408092","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>This investigation aimed to construct and validate a predictive nomogram for assessing the likelihood of target lesion revascularization (TLR) following drug-coated balloon (DCB) treatment in patients with coronary artery disease (CAD).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients and Methods</h3>\u0000 \u0000 <p>A retrospective analysis was conducted on 851 consecutive patients with CAD who had de novo lesions and underwent DCB treatment between January 2021 and January 2022. The primary outcome assessed was the occurrence of TLR. Predictive factors were identified through multivariate regression analysis, with patients randomly assigned to either a training cohort (70%, <i>n</i> = 578) or a validation cohort (30%, <i>n</i> = 273). Independent risk factors were determined using univariate and multivariate logistic regression. The nomogram was developed using <i>R</i> software and evaluated for its discriminative ability (C-statistic), calibration (through calibration plots), and clinical utility (via decision curve analysis, DCA). Internal validation was performed using bootstrap resampling with 1000 iterations to correct for optimism.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among the 851 patients enrolled, TLR occurred in 66 cases, corresponding to an incidence of 7.8%. Multivariable logistic regression analysis identified four independent predictors of TLR, which were subsequently incorporated into the nomogram: lesion length (OR 1.101, 95% CI 1.053–1.151, <i>p</i> = 0.001), vessel diameter (OR 3.513, 95% CI 2.279–5.417, <i>p</i> = 0.001), multiple lesions (OR 2.919, 95% CI 1.120–7.612, <i>p</i> = 0.028), and calcified lesions (OR 2.452, 95% CI 1.357–4.432, <i>p</i> = 0.003). The nomogram demonstrated good discriminatory performance, achieving C-indices of 0.820 (95% CI: 0.747–0.893) in the training cohort and 0.802 (95% CI: 0.643–0.961) in the validation cohort. Calibration analysis revealed concordance between nomogram-predicted probabilities and observed TLR frequencies. Furthermore, decision curve analysis substantiated the clinical utility of the nomogram for effective risk stratification.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The nomogram demonstrates good predictive accuracy and discriminative ability, serving as a practical tool for identifying high risk of TLR post-DCB treatment in CAD patients. Its integration into clinical practice could optimize postoperative monitoring and therapeutic decision-making.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2026 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/4408092","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149145820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Rotational and Orbital Atherectomy in Calcified Coronary Lesions: Systematic Review and Meta-Analysis","authors":"Mochamad Faishal Riza,&nbsp;Mohammad Saifur Rohman,&nbsp;Shalahuddin Suryo Baskoro,&nbsp;Ayu Pramitha Wulandari,&nbsp;Agustina Tri Endharti,&nbsp;Hani Susianti","doi":"10.1155/joic/1637724","DOIUrl":"https://doi.org/10.1155/joic/1637724","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Severe coronary artery calcification is one of the most challenging lesion subsets encountered in percutaneous coronary intervention (PCI) and frequently demands atherectomy-based plaque modification. Whether rotational atherectomy (RA) outperforms orbital atherectomy (OA)—or vice versa—remains unclear.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We performed a PRISMA 2020–compliant systematic review and meta-analysis (PROSPERO: CRD420261358631), searching five databases. The final search was conducted on April 30, 2024. The primary endpoint was MACE; secondary endpoints covered mortality, MI, TVR, TLR, and procedural complications, all modeled with random effects.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Eleven studies (&gt; 80,000 patients) qualified. MACE, all-cause mortality, MI, and TLR were without a statistically significant difference between devices. TVR was higher with RA (RR 2.18, 95% CI 1.13–4.22). Perforation and tamponade favored RA in primary analyses, but those findings proved dependent on one dominant registry in sensitivity testing.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Available evidence does not demonstrate a clear overall clinical advantage of either RA or OA. Outcome differences between devices appear to stem from procedural and lesion-selection factors rather than intrinsic device properties, pointing toward an individualized, anatomically guided approach to atherectomy selection. Observed outcome differences may be influenced by procedural factors and lesion characteristics rather than device characteristics alone.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2026 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/1637724","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149145811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-Reported Health-Related Quality of Life One Year After Transcatheter Aortic Valve Implantation: A Single-Center Prospective Observational Registry Study","authors":"Max Briefs,&nbsp;Janis Fliegenschmidt,&nbsp;Johannes Trabert,&nbsp;Claudia Bunge,&nbsp;Jan Wiesemann,&nbsp;Catharina Middeke,&nbsp;Astrid Bergmann,&nbsp;Muhammed Gerçek,&nbsp;Tanja Rudolph,&nbsp;Nikolai Hulde,&nbsp;Vera von Dossow","doi":"10.1155/joic/5886721","DOIUrl":"https://doi.org/10.1155/joic/5886721","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Transcatheter aortic valve implantation (TAVI) is increasingly performed, yet long-term patient-reported outcomes (PROs) and health-related quality of life (HR-QoL) remain insufficiently characterized. Identifying factors associated with HR-QoL may contribute to patient-centered care. This study aimed to identify demographic and perioperative factors associated with physical and mental HR-QoL at 1-year follow-up after TAVI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Among 337 patients undergoing TAVI, 211 1-year survivors with complete 12-Item Short Form Health Survey (SF-12) constituted the analytical cohort. A frailty- and delirium-screened subgroup comprised 112 patients. HR-QoL at 1 year was assessed using the Physical Component Summary (PCS) and Mental Component Summary (MCS) of the SF-12. Associations between demographic and perioperative variables and 1-year PCS and MCS were evaluated using multivariable linear regression models.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean age was 83.3 years, and 42.2% were female. One-year mortality was 7.7% (26/337). Older age (B −9.5, 95% confidence interval (CI) −14.8 to −4.2, <i>p</i> &lt; 0.001), anemia (B −4.2, 95% CI −8.1 to −0.4, <i>p</i> = 0.030), obesity (B −5.4, 95% CI −9.4 to −1.4, <i>p</i> = 0.009), smoking (B −7.9, 95% CI −13.6 to −2.2, <i>p</i> = 0.007), and higher symptom burden (B −14.6, 95% CI −23.7 to −5.6, <i>p</i> = 0.002) were associated with lower PCS, as was physical frailty (B −7.4, 95% CI −14.2 to −0.6, <i>p</i> = 0.032). Female sex (B −4.1, 95% CI −7.5 to −0.7, <i>p</i> = 0.019), preexisting diabetes mellitus (B −4.0, 95% CI −7.7 to −0.3, <i>p</i> = 0.033) and physical prefrailty (B −5.9, 95% CI −11.4 to −0.5, <i>p</i> = 0.034) were associated with lower MCS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Among 1-year survivors, several demographic and clinical characteristics, including physical frailty, were independently associated with lower HR-QoL scores. These associations are conditional on survival and questionnaire completion and may therefore be affected by survivorship and response selection, as well as the absence of baseline HR-QoL assessment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2026 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/5886721","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149146525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tricuspid Transcatheter Edge-to-Edge Repair Trends and Predictors of Outcomes: Insight From National Inpatient Sample Database","authors":"Sameh Nassar,&nbsp;Zahoor Khan,&nbsp;Amanda Nguyen,&nbsp;Muhammad Zia Khan,&nbsp;Salman Zahid,&nbsp;Waleed Alruwaili,&nbsp;Richard Kovach,&nbsp;Chunguang Chen,&nbsp;Muhammad Raza","doi":"10.1155/joic/2682700","DOIUrl":"https://doi.org/10.1155/joic/2682700","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Severe tricuspid regurgitation (TR) is associated with significant morbidity and mortality and has limited treatment options. Surgical intervention is often contraindicated due to high perioperative risk, creating a demand for minimally invasive alternatives like tricuspid transcatheter edge-to-edge repair (T-TEER). The FDA approval of the TriClip G4 System in April 2024 marked a pivotal advancement in TR management.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study analyzed trends, outcomes, and predictors associated with T-TEER placement using the National Inpatient Sample database from 2018 to 2021.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective analysis was conducted on 1960 patients undergoing T-TEER identified via ICD-10-CM coding. Patient demographics, comorbidities, procedural complications, in-hospital mortality, length of stay, and hospitalization costs were analyzed using logistic regression models. Key outcomes included trends in procedural volume, mortality, complications, and economic impact.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Over the study period, T-TEER procedures increased significantly, with improved outcomes and reduced hospital stays. Female patients experienced lower mortality and complications compared to males (OR 0.43, 95% CI 0.23–0.83). Patients with comorbidities, including pulmonary hypertension, liver disease, and peripheral vascular disease, demonstrated higher complication rates. Length of hospital stay decreased from three days in 2018–2019 to two days in 2019–2021, while median hospitalization costs remained high, particularly for patients with congestive heart failure and coagulopathy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>T-TEER offers a viable alternative for patients with high-risk TR, with increasing utilization and subsequent decrease in procedural complications over time. While our study highlights some disparities in outcomes among patients with complex comorbidities, further studies are warranted to assess long-term procedural efficacy, safety, and outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2026 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/2682700","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149146505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of COVID-19 With the Proportion and Severity of Coronary Slow Flow Phenomenon: A Comparative Analysis","authors":"Ali Mansoursamaei,&nbsp;Erfan Kazemi,&nbsp;Maryam Mansoursamaei,&nbsp;Marzieh Rohani-Rasaf,&nbsp;Hossein Sheibani","doi":"10.1155/joic/5576998","DOIUrl":"https://doi.org/10.1155/joic/5576998","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The coronary slow flow phenomenon (CSFP) is an angiographic finding attributed to coronary microvascular dysfunction. Given the overlap in cardiovascular manifestations between COVID-19 and CSFP, the potential association of COVID-19 with the proportion and angiographic severity of CSFP remains poorly understood.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective cross-sectional study included 242 eligible patients with angiographically diagnosed CSFP at Imam Hossein Hospital, Shahroud, Iran, from April 2018 to April 2023. The primary analysis compared the proportion of CSFP among all coronary angiography procedures before and during the COVID-19 pandemic. Secondary analyses compared clinical characteristics and laboratory parameters according to COVID-19 status and angiographic CSFP severity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>During the COVID-19 pandemic, the proportion of angiographically diagnosed CSFP among patients undergoing coronary angiography increased significantly compared with the prepandemic period (8.0% vs. 3.5%, <i>p</i> &lt; 0.01). However, angiographic CSFP severity did not differ before and during the pandemic (<i>p</i> = 0.58). Among the 242 eligible patients, 88 (36.4%) had documented COVID-19. Overall, 113 patients (46.7%) had mild CSFP and 129 patients (53.3%) had severe CSFP. Multivariable logistic regression, adjusted for age, sex, and underlying disease, showed that non-COVID-19 patients had higher odds of severe CSFP than COVID-19 patients (OR = 1.73; 95% CI, 1.013, 2.960).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study provides novel evidence regarding changes in the proportion and angiographic severity of CSFP before and during the COVID-19 pandemic. The findings suggest that the observed differences may reflect changes in clinical presentation, referral patterns, or diagnostic evaluation during the pandemic rather than evidence of a causal relationship between COVID-19 and CSFP pathophysiology. Further prospective studies with precise exposure timing and functional assessment of coronary microvascular function are required to better clarify the relationship between COVID-19 and CSFP pathophysiology and the mechanisms underlying these observations.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2026 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/5576998","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149048490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Associated With Progression of Nonculprit Lesions in Elderly Unstable Angina Patients Following Successful CTO-PCI: A Retrospective Single-Center Analysis","authors":"Jian Wang,&nbsp;Song-Yuan He,&nbsp;Tian-Zhen Wang","doi":"10.1155/joic/6932106","DOIUrl":"https://doi.org/10.1155/joic/6932106","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Despite successful revascularization of chronic total occlusions (CTOs), the fate of nonculprit lesions (NCTOLs) in elderly patients with unstable angina (UA) remains a concern. This investigation sought to pinpoint factors predictive of NCTOL angiographic worsening in this high-risk demographic.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted a retrospective cohort study enrolling 250 consecutive elderly (≥ 65 years) UA patients who underwent successful CTO-PCI at a single tertiary center between January 2018 and December 2024 and completed 12-month angiographic follow-up. The primary endpoint was angiographic progression of a preselected NCTOL, defined as an increase in diameter stenosis by ≥ 10%. Baseline clinical, laboratory, and procedural variables were compared between progressors and nonprogressors. Independent correlates were identified through partial correlation and multivariable logistic regression analyses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>At 12 months, 85 patients (32.2%) demonstrated NCTOL progression. After multivariable adjustment, higher log-transformed Lp(a) (ln-Lp(a), adjusted OR = 1.72, 95% CI: 1.31–2.26, <i>p</i> &lt; 0.001), higher log-transformed CRP (ln-CRP, adjusted OR = 1.58, 95% CI: 1.22–2.04, <i>p</i> &lt; 0.001), greater NCTOL length (adjusted OR per mm = 1.06, 95% CI: 1.02–1.10, <i>p</i> = 0.002), and retrograde PCI approach (adjusted OR = 2.14, 95% CI: 1.17–3.91, <i>p</i> = 0.013) each independently correlated with progression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In this elderly UA cohort, elevated Lp(a) and CRP, longer NCTOL, and retrograde CTO-PCI were independently tied to 12-month angiographic NCTOL deterioration. These observations underscore the potential roles of residual inflammation and lipid-related risk, alongside baseline disease complexity. Given the observational design, causality cannot be inferred; validation in prospective multicenter studies with extended clinical follow-up is essential.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2026 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/6932106","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149048360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug-Coated Balloon Intervention in Large Coronary Arteries: Immediate Procedural Results and One-Year Follow-Up","authors":"Alexander Loch,&nbsp;Vineesh Chandra Segaran,&nbsp;David Kwong Yi Vern,&nbsp;Victoria Wen Yeng Teoh,&nbsp;Mahmoud Danaee","doi":"10.1155/joic/6072388","DOIUrl":"https://doi.org/10.1155/joic/6072388","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Drug-coated balloons (DCBs) are an established treatment for in-stent restenosis and small-vessel coronary disease, but evidence for large de novo coronary artery lesions remains limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We prospectively evaluated patients undergoing percutaneous coronary intervention (PCI) with DCB for de novo lesions in large coronary arteries (reference vessel diameter ≥ 2.75 mm). All lesions underwent adequate predilatation, and DCBs were used as the definitive treatment strategy. Bailout stenting was performed in cases of significant recoil or flow-limiting dissection. Outcomes included procedural success, in-hospital complications, and major adverse cardiovascular events (MACEs) at 12-month follow-up, defined as cardiac death, target vessel myocardial infarction, or clinically driven target lesion revascularization (TLR).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 539 DCB-treated lesions were evaluated, of which 451 were excluded. The final cohort comprised 88 de novo lesions in large coronary vessels from 75 patients. DCB-only treatment was performed in 65.9%; 34.1% underwent additional PCI with stenting of nonindex lesions. Post-DCB dissections occurred in 50% and were predominantly NHLBI type A. Stenting was required in three cases, including one acute vessel closure, one severe recoil with residual stenosis during the index procedure, and one early vessel closure 11 h after the index procedure requiring repeat PCI. Mean acute gain on QCA was 0.93 ± 0.45 mm. Complete 12-month follow-up was achieved in 100% of patients. MACE at 12-month follow-up occurred in 2.7% (2/75), comprising one non-ST-segment elevation myocardial infarction and one clinically driven TLR. TLR was 1.3% at 12 months. One noncardiac death occurred and was not included in the MACE endpoint. No stroke or major bleeding was observed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>DCB angioplasty in selected de novo large coronary lesions was feasible and associated with high procedural success and favorable 1-year outcomes. Larger studies with longer follow-ups are warranted to confirm these findings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2026 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/6072388","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148994593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transapical TAVR Using a Modified J-Valve for Pure Aortic Regurgitation in Large Aortic Annuli: A Single-Center Experience","authors":"Chunshui Liang,&nbsp;Mingwen Li,&nbsp;Zezhou Feng,&nbsp;Mei Yang,&nbsp;Yingbin Xiao,&nbsp;Ruiyan Ma,&nbsp;Zhao Jian","doi":"10.1155/joic/3823493","DOIUrl":"https://doi.org/10.1155/joic/3823493","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate the safety and efficacy of transapical implantation of a modified J-Valve in patients with pure aortic regurgitation (AR) and large aortic annuli (&gt; 29 mm).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective single-center study included 10 high surgical risk patients (STS-PROM: 8.3%–13.1%) with pure AR and annular diameters &gt; 29 mm who underwent transapical implantation of a J-Valve prosthesis externally reinforced with a Dacron patch between December 2018 and September 2024. Endpoints were defined according to the Valve Academic Research Consortium-3 (VARC-3) criteria. Procedural outcomes, echocardiographic data, and 30-day complications were analyzed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All procedures were technically successful, with no intraoperative mortality, stroke, or vascular complications. Postoperatively, one patient required permanent pacemaker implantation. Perivalvular leakage (PVL) was observed in five patients (four trace/mild, one moderate) immediately postprocedure. At a median follow-up of 6.5 months, PVL was present in three patients (two trace, one moderate). Significant reductions in left ventricular dimensions and stable hemodynamic parameters were noted. No subclinical leaflet thrombosis occurred.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Transapical implantation of a modified J-Valve with an external Dacron skirt appears technically feasible with acceptable short-term safety for highly selected high-risk patients with pure AR and large annuli (&gt; 29 mm). However, the limited sample size precludes broad applicability, and longer term follow-up is required.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2026 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/3823493","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148942811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}