Journal of interventional cardiology最新文献

{"title":"Clinical Impact of Intraoperative Temperature Strategy in CABG: A Normothermic Advantage","authors":"Maryam Bahramian,&nbsp;Mozhgan Bahramian,&nbsp;Ahmad Amouzeshi,&nbsp;Mohammad Esmatinia,&nbsp;Ali Bonyad","doi":"10.1155/joic/1666151","DOIUrl":"https://doi.org/10.1155/joic/1666151","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The optimal temperature strategy during cardiopulmonary bypass (CPB) for coronary artery bypass grafting (CABG) remains debated. We compared perioperative outcomes between normothermic and hypothermic CPB in a single-center cohort in Iran.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective cohort of 98 consecutive adults were undergoing isolated, on-pump CABG at Razi Hospital (March 2020–March 2021). Patients were grouped by intraoperative temperature strategy (normothermia 35°C–37°C without topical cooling vs. hypothermia 28°C–32°C with topical cooling as used). Data were abstracted from charts using a predefined checklist (demographics/comorbidities, operative details, intra-/postoperative transfusion and fluid balance, electrolytes/renal indices, complete blood count, ICU/ward length of stay, 12 h core temperature, mortality, and neurological events). Two-sided tests were used with <i>α</i> = 0.05.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Groups were balanced in baseline characteristics. Compared to normothermia, hypothermia required more intraoperative packed cells (mean: 476 vs. 191 mL; <i>p</i> &lt; 0.001), while postoperative transfusion until discharge was similar (636 vs. 560 mL; <i>p</i> = 0.42). ICU (2.2 vs. 1.9 days; <i>p</i> &lt; 0.001) and ward stay (5.4 vs. 3.8 days; <i>p</i> &lt; 0.001) were longer with hypothermia. Postoperative sodium increased in normothermia (<i>p</i> &lt; 0.001) but not in hypothermia (<i>p</i> = 0.173); both groups showed increased urea/creatinine and decreased RBC/Hb/Hct postoperatively. Serum intake and urine output were higher intra- and postoperatively in hypothermia (all <i>p</i> &lt; 0.001). Ejection fraction and 12-h core temperature did not differ; mortality and CVA were rare and comparable.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In this cohort, normothermic CPB for isolated CABG was associated with fewer intraoperative transfusions and shorter ICU/ward stays than hypothermia, with otherwise similar short-term safety signals. Prospective studies should test long-term and patient-reported outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/1666151","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145223843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Value of GRACE Score and Left Ventricular Ejection Fraction in Non-ST-Segment Elevation Myocardial Infarction","authors":"Yong Hoon Kim,&nbsp;Ae-Young Her,&nbsp;Seung-Woon Rha,&nbsp;Cheol Ung Choi,&nbsp;Byoung Geol Choi,&nbsp;Soohyung Park,&nbsp;Jung Rae Cho,&nbsp;Min-Woong Kim,&nbsp;Ji Young Park,&nbsp;Myung Ho Jeong","doi":"10.1155/joic/3838955","DOIUrl":"https://doi.org/10.1155/joic/3838955","url":null,"abstract":"<p><b>Background:</b> To provide more useful information due to the lack of published results to date, we analyzed the 3-year clinical outcomes of patients with non-ST-segment elevation myocardial infarction (NSTEMI) using the Global Registry of Acute Coronary Events (GRACE) score and the degree of left ventricular ejection fraction (LVEF).</p><p><b>Methods:</b> In total, 4558 patients were stratified into two groups: GRACE score &gt; 140 (group A) and GRACE score ≤ 140 (Group B). Each group was further subdivided into heart failure (HF) with reduced EF (HFrEF), HF with mildly reduced EF (HFmrEF), and HF with preserved EF (HFpEF). The primary outcome was all-cause mortality, and the secondary outcomes were cardiac death (CD), non-CD, recurrent MI, and hospitalization for HF (HHF).</p><p><b>Results:</b> After adjustment, in Group A, the 3-year rates of all-cause mortality (<i>p</i> &lt; 0.001 for all), CD, and HHF were higher in the HFrEF subgroup than in the HFmrEF and HFpEF subgroups, with similar outcomes between the HFmrEF and HFpEF subgroups. In Group B, the HFrEF subgroup had higher CD (<i>p</i> = 0.019) and HHF rates than did the HFmrEF subgroup and higher all-cause mortality (<i>p</i> = 0.001), CD (<i>p</i> &lt; 0.001), and HHF rates than the HFpEF subgroup. All-cause mortality rate between the HFrEF and HFmrEF subgroups was similar, whereas the HFmrEF subgroup had a higher all-cause mortality rate than did the HFpEF subgroup (<i>p</i> = 0.022). Group A had worse clinical outcomes than Group B across all LVEF subgroups.</p><p><b>Conclusion:</b> Although the HFrEF subgroup had a higher all-cause mortality rate than did the HFpEF subgroup, all-cause mortality patterns between the HFrEF and HFmrEF subgroups and between the HFmrEF and HFpEF subgroups varied according to the GRACE score. However, broader studies with a larger number of patients are needed.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/3838955","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping the Evolution of Drug-Coated Balloon Research in Coronary Artery Disease: A 2006–2023 Bibliometric and Visual Analysis","authors":"Jiayang Dong,&nbsp;Zhiqiang Zhang,&nbsp;Jiayi Sun,&nbsp;Xinyue Yang,&nbsp;Wenjuan Zhang","doi":"10.1155/joic/1837323","DOIUrl":"https://doi.org/10.1155/joic/1837323","url":null,"abstract":"<p><b>Background:</b> Drug-coated balloons (DCBs) have emerged as an innovative technology for coronary artery disease treatment. However, bibliometric research on DCB development trends is still lacking.</p><p><b>Methods:</b> We performed a bibliometric analysis of DCB-related publications from 2006 to 2023, extracted from the Web of Science Core Collection database. Analysis dimensions included temporal publication patterns, distributions of countries/regions and institutions, author and journal productivity/impact, keyword co-occurrence and bursts, collaboration networks, and seminal studies. Visualization tools such as the R package “Bibliometrix,” VOSviewer, and CiteSpace facilitated the graphical mapping of research hotspots.</p><p><b>Result:</b> This bibliometric analysis of 781 DCB-related publications shows an increasing annual output since 2011, exceeding 100 in 2021. Germany, China, Italy, Japan, and the United States were dominant in DCB research, with Germany accruing the highest citation count of 6477. The Technical University of Munich published the most DCB-related papers (<i>n</i> = 22). Bruno Scheller had the highest author productivity (<i>n</i> = 45) and citations (<i>n</i> = 3235). Analyses of keyword co-occurrence showed prevalent foci encompassing “DCB,” “drug-eluting stent,” and “in-stent restenosis.” Newly emerging topics contain “DCB-only strategy” and intravascular imaging.</p><p><b>Conclusion:</b> The research activities on DCB have greatly expanded, with significant advancements in device design and indications. Recent priorities signal a shift towards physiology/intravascular imaging–guided usage and DCB as standalone therapies for more de novo coronary lesions. Ongoing advances will consolidate DCB in guidelines and daily practice. Our analysis provides strategic insights, informing research and clinical directions.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/1837323","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145062702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Instantaneous Wave-Free Ratio-Guided Interventions in Side Branches Improve Results in Bifurcation Lesions Compared to Conventional Techniques","authors":"Zia-ul-Sabah,&nbsp;Adel Masswary,&nbsp;Mohammed Alahmari,&nbsp;Abdullah Asiri,&nbsp;Javed Iqbal Wani,&nbsp;Humayoun Durrani,&nbsp;Shahid Aziz,&nbsp;Hafed Ahmad Alaskary,&nbsp;Ali Alqarni,&nbsp;Ayyub Ali Patel","doi":"10.1155/joic/1482690","DOIUrl":"https://doi.org/10.1155/joic/1482690","url":null,"abstract":"<p><b>Background:</b> In coronary lesions characterized by bifurcation anatomies, provisional side-branch intervention is the preferred treatment approach. However, there is a well-documented discrepancy between angiographic evaluations of blood flow obstruction and the actual functional severity of bifurcation lesions. Additionally, the use of fractional flow reserve (FFR) carries notable side effects primarily associated with the necessity of adenosine administration. Given the demonstrated noninferiority of the instantaneous wave-free ratio (iFR) compared to FFR, this study aimed to assess the clinical and functional benefits of iFR-guided side-branch ballooning which involving drug-eluting balloon inflation in side branch in comparison to conventional intervention techniques for bifurcation lesions.</p><p><b>Methods:</b> In this prospective cohort study, a total of 100 patients with coronary lesions characterized by bifurcation anatomies were enrolled and randomly assigned to two groups: the iFR-based intervention group, which utilized only side-branch intervention involving drug-eluting balloon inflation, and the conventional intervention group. Both groups were monitored for 12 months postintervention to assess various clinical and functional endpoints.</p><p><b>Results:</b> In the iFR-guided group, only 2 patients (4%) met the primary endpoint (a composite of target bifurcation-related nonfatal myocardial infarction, target bifurcation revascularization, and any unplanned revascularization) compared to 10 patients (20%) in the conventional group (<i>p</i> = 0.01). The study also demonstrated the superiority of iFR-guided drug-eluting balloon inflation in side branches over conventional interventional procedures for bifurcation lesions, as evidenced by a reduction in fluoroscopy time (mean difference [MD] = −8.9 min, 95% confidence interval [CI] = −15.6 to −2.1, <i>p</i> = 0.01), intervention duration (MD = −11.6 min, 95% CI = −20.5 to −2.8, <i>p</i> = 0.01), and length of hospital stay (MD = −1 day, 95% CI = −1.2 to −0.80, <i>p</i> &lt; 0.0001). Additionally, the amount of contrast media used in the iFR-guided intervention group was significantly lower than that in the conventional treatment group (<i>p</i> &lt; 0.0001).</p><p><b>Conclusions:</b> iFR-guided side-branch intervention involving drug-eluting balloon inflation in bifurcation lesions was significantly better when compared to conventional interventions in terms of clinical and functional outcomes in patients with coronary lesions characterized by bifurcation anatomies.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/1482690","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preprocedural Risk Factors of In-Hospital Mortality Following Percutaneous Coronary Intervention: A Systematic Review of Risk-Adjustment Models","authors":"Mohammad Rocky Khan Chowdhury,&nbsp;Dion Stub,&nbsp;Diem Dinh,&nbsp;Hasina Akhter Chowdhury,&nbsp;Baki Billah,&nbsp;Md. Nazmul Karim","doi":"10.1155/joic/8760459","DOIUrl":"https://doi.org/10.1155/joic/8760459","url":null,"abstract":"<p>Assessing the preprocedural risk of mortality following percutaneous coronary intervention (PCI) is crucial for clinical decision-making, quality registries, and performance monitoring. This systematic review aims to summarize preprocedural factors associated with in-hospital mortality post-PCI. A systematic search of MEDLINE, EMBASE, CINAHL, and Web of Science was conducted up to April 2024, without language restrictions, to identify preprocedural factors associated with in-hospital mortality post-PCI. The information was systematically evaluated and descriptively summarized following the CHhecklist for critical Appraisal and data extraction for systematic Reviews of prediction Modeling Studies (CHARMS) checklist. The search initially identified 9552 studies, with 28 articles ultimately included in the final analysis. The pooled prevalence of in-hospital mortality post-PCI was 1.63%, whereas it was 6.40% for patients with acute coronary syndrome (ACS). A total of 77 independent preprocedural factors were found to be significantly associated with in-hospital mortality, of which 22 were consistently reported across multiple studies and identified as potential key factors. Factors most frequently reported in various studies included, but not limited to, ACS (<i>n</i> = 27, 96.4%), renal failure (<i>n</i> = 24, 85.7%), age (<i>n</i> = 19, 67.9%), gender (<i>n</i> = 16, 57.1%), cardiac events (<i>n</i> = 15, 53.6%), ejection fraction (<i>n</i> = 15, 53.6%), vascular disease (<i>n</i> = 12, 42.9%), heart failure (<i>n</i> = 12, 42.9%), body mass index (<i>n</i> = 10, 35.7%), lesion location (<i>n</i> = 9, 32.1%), diabetes (<i>n</i> = 8, 28.6%), and vessel disease (<i>n</i> = 8, 28.6%). Eleven articles (39.2%) used imputation methods to handle missing data. Logistic regression was used by 19 articles (67.9%), and five articles (18.6%) used the machine learning (ML) method. Nineteen articles (67.9%) reported the discriminatory performance of the models using receiver operating characteristic (ROC) score ranging from 0.776 to 0.960. Incorporating the 22 preprocedural factors identified in this study can aid clinicians in decision-making for high-risk cases. To improve risk adjustment models, these factors should be integrated, missing data carefully managed, models validated, and ML techniques utilized.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/8760459","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144923461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rotational Atherectomy for Coronary Chronic Total Occlusion With Severe Calcification: A Preliminary Study","authors":"Bin Zhang,&nbsp;Yurong Sun,&nbsp;Zhizhu Tian,&nbsp;Bo Luan","doi":"10.1155/joic/5574643","DOIUrl":"https://doi.org/10.1155/joic/5574643","url":null,"abstract":"<p><b>Objective:</b> The aim of this study was to investigate the therapeutic effects and 1-year outcomes of RA in patients with severe calcified coronary artery CTO.</p><p><b>Methods:</b> Data were collected from 395 individuals with severe calcified CTO who received treatment at Liaoning Provincial People’s Hospital. These patients were categorized into two groups: those receiving RA and those receiving non-RA. The association between RA and the incidence of MACCEs within the 1-year postoperative period was evaluated via the Cox proportional hazards model.</p><p><b>Results:</b> In patients with CTO exhibiting severe calcification, we compared various factors, including age, BMI, history of diabetes, left ventricular ejection fraction, low-density lipoprotein levels, hemoglobin, creatinine, the glomerular filtration rate, and family history of coronary heart disease, between those who underwent RA and those who did not. In addition, we assessed medical history, cardiac bypass surgery, cerebrovascular disease, coronary interventions, the number of CTO lesions, operation time, irradiation time, contrast agent usage, and the incidence rates of MACCEs, all of which were found to be statistically significant (<i>p</i> &lt; 0.05). These significant indicators and the occurrence of MACCEs within 1 year were incorporated into the Cox survival regression analysis, which revealed that the use of RA (<i>p</i> = 0.010, HR: 0.457, 95% CI: 0.251–0.830) was independently correlated with a lower MACCE rate. Furthermore, the survival curve of the non-RA group was significantly lower than that of the RA group.</p><p><b>Conclusion:</b> Intervention with RA is associated with a lower MACCE rate in patients with severely calcified CTO. These findings imply that the potential of RA could be an alternative treatment modality in these patients. However, more evidence and further randomized controlled studies are needed to verify these findings.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/5574643","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Edoxaban Monotherapy in Nonvalvular Atrial Fibrillation Patients with Coronary Artery Disease”","authors":"","doi":"10.1155/joic/9762605","DOIUrl":"https://doi.org/10.1155/joic/9762605","url":null,"abstract":"<p>D. Fukamachi, Y. Okumura, N. Matsumoto, et al., “Edoxaban Monotherapy in Nonvalvular Atrial Fibrillation Patients with Coronary Artery Disease,” <i>Journal of Interventional Cardiology</i> 2022 (2022): 5905022, https://doi.org/10.1155/2022/5905022.</p><p>In the article, the authors have identified errors in Table 2, where in the final row, ‘Noncardiovascular’ should read ‘All Cause’. The correct Table 2 is shown as follows:</p><p>Additionally, in Section 3.2. Clinical Outcomes, the following sentence should be corrected from:</p><p>“Two patients given edoxaban monotherapy and one given the combination therapy suffered a noncardiovascular death.”</p><p>To:</p><p>“Two patients given edoxaban monotherapy and one patient given the combination therapy suffered all-cause deaths (HR: 1.99; 95% CI: 0.18–21.9). Cardiovascular death, a secondary endpoint, occurred in one patient in the edoxaban monotherapy group. Noncardiovascular death occurred in one patient in both groups.”</p><p>We apologize for these errors.</p>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/9762605","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of Increased Transmitral Gradients Under Dynamic Isometric Handgrip Exercise After Edge-to-Edge Repair With the Fourth-Generation MitraClip","authors":"Giuseppe D’Ancona,&nbsp;Antonia Anna Ourani,&nbsp;Evangelos Chaidos,&nbsp;Catherine Louise Steinbach,&nbsp;Hüseyin Ince,&nbsp;Raid Al Ammareen","doi":"10.1155/joic/9920829","DOIUrl":"https://doi.org/10.1155/joic/9920829","url":null,"abstract":"<div>\u0000 <p><b>Aim:</b> Mitral regurgitation (MR) is a prevalent cardiovascular condition, and its treatment remains challenging, especially in high-risk patients. The fourth-generation MitraClip system (NTW and XTW) offers enhanced capabilities for repairing mitral valves (MVs) with complex anatomies. This study evaluates the haemodynamic function of MVs after edge-to-edge with wide MitraClip under physical stress induced by handgrip exercise stress echocardiography.</p>\u0000 <p><b>Methods:</b> This prospective study included 27 patients with severe MR. All patients underwent successful MitraClip implantation, and handgrip stress echocardiography was performed predischarge. The primary endpoint was a postprocedure mean transmitral gradient (TMG) &lt; 5 mmHg under stress. A machine learning (ML) model using logistic regression as the learner and advanced data augmentation techniques, including random splitting of data into training and testing subsets and repeating the process 50 times, were employed to ensure robustness.</p>\u0000 <p><b>Results:</b> MitraClip implantation reduced MR severity from 3.02 ± 0.22 to 0.98 ± 0.43 (<i>p</i> &lt; 0.0001). Stress-induced increases in heart rate, blood pressure and TMG were significant (TMG: 3.04 ± 0.90 mmHg at rest vs. 4.11 ± 1.53 mmHg under stress, <i>p</i> &lt; 0.0001). Thirty-seven percent of patients exhibited TMG ≥ 5 mmHg during stress. Predictors of elevated TMG included secondary MR, BMI, and multiple clip implantation (AUC = 0.90; 95% CI: 0.79–0.96). Despite increased TMG, no patients experienced significant symptoms or pathological MR.</p>\u0000 <p><b>Conclusion:</b> Wide MitraClips effectively reduce MR with satisfactory haemodynamic performance. Handgrip stress echocardiography is a feasible and valuable tool for assessing postprocedure valve function. Larger cohorts are necessary to confirm the impact of secondary MR and use of multiple clips on increased TMG under stress.</p>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/9920829","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144811101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High HDL-Cholesterol Levels Are Associated With Lower Risk of Acute Coronary Syndromes in Coronary Artery Disease","authors":"Aurélien Clerc,&nbsp;Serban Puricel,&nbsp;Yannick Faucherre,&nbsp;Jean-Luc Magnin,&nbsp;Sonja Lehmann,&nbsp;Dorian Garin,&nbsp;Charlie Ferry,&nbsp;Pascal Meier,&nbsp;Mario Togni,&nbsp;Stephane Cook","doi":"10.1155/joic/5030966","DOIUrl":"https://doi.org/10.1155/joic/5030966","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> The inverse association between HDL-cholesterol (HDL-C) levels and the risk of cardiovascular diseases is evident.</p>\u0000 <p><b>Hypothesis:</b> Our hypothesis was that higher levels of HDL-C predisposed patients with coronary artery disease (CAD) to chronic coronary syndromes (CCS) rather than acute coronary syndrome (ACS), which has not clearly been demonstrated yet.</p>\u0000 <p><b>Aim:</b> To determine, in an unselected population of patients treated with percutaneous coronary intervention (PCI), if HDL-C levels are independently higher in subjects presenting with CCS compared with those with ACS.</p>\u0000 <p><b>Methods and Results:</b> In this retrospective study, we identified 4215 patients who underwent PCI in the Cardio-FR database. A total of 2942 patients met the selection criteria and completed at least a 1-year follow-up: 1686 suffered an ACS whereas 1256 presented with CCS. We found that low HDL-C levels were significantly associated with ACS and high HDL-C levels with CCS. This was consistent across all BMI categories in both genders. In addition, higher HDL-C levels reduced the likelihood of CAD subjects developing ACS. Specifically, each mmol/L increase in HDL-C decreased the odds of ACS by 79%. Interestingly, the CCS group had more polymorbid subjects than the ACS group. At 2-year follow-up, no difference in patient-oriented composite endpoint was seen between high and low HDL-C groups.</p>\u0000 <p><b>Conclusion:</b> In an unselected population of coronary patients, HDL-C levels were consistently lower in individuals presenting with ACS compared with CCS, independently of BMI and gender. This finding strengthens the hypothesis that HDL-C plays a role in long-term protection against atherosclerotic plaque vulnerability. Considering HDL-C level still makes sense.</p>\u0000 <p><b>Trial Registration:</b> ClinicalTrials.gov identifier: NCT04185285</p>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/5030966","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144811100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring New Frontiers in Patent Fossa Ovalis Closure","authors":"Gregory A. Sgueglia,&nbsp;Achille Gaspardone","doi":"10.1155/joic/1315599","DOIUrl":"https://doi.org/10.1155/joic/1315599","url":null,"abstract":"<div>\u0000 <p>Percutaneous closure of patent fossa ovalis in patients with paradoxical embolism has gradually emerged as an increasingly compelling alternative to prolonged medical therapy. In particular, in recent years, percutaneous suture-mediated “deviceless” patent fossa ovalis closure has emerged as a revolutionary technique, offering feasibility across diverse septal anatomies and improved safety compared to implantable devices, while ensuring substantially comparable efficacy in achieving patent fossa ovalis closure. The innovative nature of percutaneous suture-mediated patent fossa ovalis closure offers a number of advantages that suggest it as the preferred primary treatment choice for patent fossa ovalis closure when feasible. Although the need for long-term follow-up data remains, controlled studies are ongoing to provide a deeper understanding of its efficacy and durability. In addition, percutaneous suture-mediated patent fossa ovalis closure has promising prospects beyond preventive indications in patients with a history of migraine, the elderly, and divers. The evolving landscape of percutaneous suture-mediated patent fossa ovalis closure is transformative, demonstrating a paradigm shift in patient care options and redefining therapeutic approaches for patent fossa ovalis–related conditions.</p>\u0000 </div>","PeriodicalId":16329,"journal":{"name":"Journal of interventional cardiology","volume":"2025 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/joic/1315599","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144751411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}