Journal of Mathematical and Fundamental Sciences最新文献_第5页

Delay Time Parameter and Its Confidence Interval of Predictive Time Series of COVID-19 Outbreak Between the First and the Second Wave 第一波和第二波COVID-19爆发预测时间序列的延迟时间参数及其置信区间

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Journal of Mathematical and Fundamental Sciences Pub Date : 2021-10-12 DOI: 10.5614/j.math.fund.sci.2021.53.2.9

R. Sunthornwat, S. Sookkhee

{"title":"Delay Time Parameter and Its Confidence Interval of Predictive Time Series of COVID-19 Outbreak Between the First and the Second Wave","authors":"R. Sunthornwat, S. Sookkhee","doi":"10.5614/j.math.fund.sci.2021.53.2.9","DOIUrl":"https://doi.org/10.5614/j.math.fund.sci.2021.53.2.9","url":null,"abstract":"The outbreak of coronavirus disease 2019 (COVID-19) has become a major problem facing humans all around the world. For governments, in order to deal with the outbreak and protect the population, it is important to predict the number of infectious cases in the future to monitor the COVID-19 situation. This research aimed to compare the effectiveness of the logistic and the delay logistic time series in predicting the total number of infectious cases by using actual data from four countries, i.e. Thailand, South Korea, Egypt, and Nigeria. The total number of COVID-19 cases was collected during the first and the second wave of the COVID-19 outbreak. The validation and accuracy of the predictive growth curve time series were determined based on statistical values, i.e. the coefficient of determination and the root mean squared percentage error. It was found that the logistic time series was more appropriate for predicting the first wave in the four countries. For the second wave, the delay logistic time series was preferable. Moreover, the confidence interval based on Chebyshev’s inequality of delay time between the first and the second wave of the COVID-19 outbreak is also proposed.","PeriodicalId":16255,"journal":{"name":"Journal of Mathematical and Fundamental Sciences","volume":"54 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77606490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Non-pharmacological Interventions on the Dynamics of Schistosomiasis 非药物干预在血吸虫病动力学中的作用

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Journal of Mathematical and Fundamental Sciences Pub Date : 2021-09-23 DOI: 10.5614/j.math.fund.sci.2021.53.2.6

Agatha Abokwara, C. E. Madubueze

{"title":"The Role of Non-pharmacological Interventions on the Dynamics of Schistosomiasis","authors":"Agatha Abokwara, C. E. Madubueze","doi":"10.5614/j.math.fund.sci.2021.53.2.6","DOIUrl":"https://doi.org/10.5614/j.math.fund.sci.2021.53.2.6","url":null,"abstract":"Schistosomiasis is a neglected tropical disease affecting communities surrounded by water bodies where fishing activities take place or people go to swim, wash and cultivate crops. It poses a great risk to the health and economic life of inhabitants of the area. This study was carried out to evaluate the impact of public health education and snail control measures on the incidence of schistosomiasis. A model was developed with attention given to the snail and human populations that are the hosts of the cercariae and miracidia respectively. The existence and stability of disease-free and endemic equilibrium states were established. The disease-free and endemic equilibrium states were shown to be locally asymptotically stable whenever the basic reproduction number was less than unity. Numerical simulations of the model were carried out to evaluate the impact of interventions (public health education and snail control measures) on schistosomiasis transmission. It was observed that the implementation of low coverage snail control with highly efficacious molluscicide and massive public health education will make the basic reproduction number smaller than unity, which implies the eradication of schistosomiasis in the population.","PeriodicalId":16255,"journal":{"name":"Journal of Mathematical and Fundamental Sciences","volume":"16 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75503871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Isolation and Antibacterial Properties of Phenyl Acrylic Acid Derivatives from Balanophora elongata Blume 龙葵苯丙烯酸衍生物的分离及抗菌性能研究

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Journal of Mathematical and Fundamental Sciences Pub Date : 2021-09-17 DOI: 10.5614/j.math.fund.sci.2021.53.2.5

D. Arbain, A. Bakhtiar, N. Syafni, N. -, Goldha Faroliu, N. Putra

引用次数: 1

Docking Studies and Molecular Dynamics Simulation of Compounds Contained in Kaempferia Galanga L. to Lipoxygenase (LOX) for Anti-Inflammatory Drugs 高良姜山柰中化合物与消炎药脂氧合酶的对接研究及分子动力学模拟

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Journal of Mathematical and Fundamental Sciences Pub Date : 2021-09-08 DOI: 10.5614/j.math.fund.sci.2021.53.2.4

S. Supandi, Yeni Yeni, L. Dwita

{"title":"Docking Studies and Molecular Dynamics Simulation of Compounds Contained in Kaempferia Galanga L. to Lipoxygenase (LOX) for Anti-Inflammatory Drugs","authors":"S. Supandi, Yeni Yeni, L. Dwita","doi":"10.5614/j.math.fund.sci.2021.53.2.4","DOIUrl":"https://doi.org/10.5614/j.math.fund.sci.2021.53.2.4","url":null,"abstract":"Inflammation is a self-protective response to start the healing process. An anti-inflammatory target worth developing are lipoxygenase inhibitors, which have been studied for several diseases, including severe respiratory disease. This research had the goals of estimating the activity of 21 compounds from K. galanga to inhibit the lipoxygenase (LOX) and estimating the bond stability of the ligand-LOX complex. Based on the compound’s affinity for LOX, the compounds in K. galanga were selected by utilizing the PLANTS docking software, with zileuton as the reference ligand. The GROMACS application was used to simulate the molecular dynamics of the LOX-ligand complex at 310 K. Based on the chemPLP score, most of the 21 K. galanga compounds showed a higher affinity towards 5-LOX compared to zileuton. δ-3-carene had the best affinity for 5-LOX. In the simulation of molecular dynamics until 20 ns, the RMSD of δ-3-carene and 5-LOX was not more than 0.03 nm or 0.3 Å, indicating that the whole system showed decent stability and had ‑1.67392 x 106 kcal/mol as the average potential energy. The results showed that K. galanga contains active components of 5-LOX inhibitors that could be developed.","PeriodicalId":16255,"journal":{"name":"Journal of Mathematical and Fundamental Sciences","volume":"3 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75815871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Optimal Control Problem for Cholera Disease and Cost-Effectiveness Analysis 霍乱疾病的最优控制问题及成本效益分析

IF 0.7

Journal of Mathematical and Fundamental Sciences Pub Date : 2021-09-08 DOI: 10.5614/j.math.fund.sci.2021.53.2.3

Jhoana P. Romero–Leiton, M. Ozair, Takasar Hussaing

引用次数: 2

A Study on Characteristics and Comparison of Evaporation Estimation Methods in Bandung 万隆地区蒸发量估算方法的特点及比较研究

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Journal of Mathematical and Fundamental Sciences Pub Date : 2021-08-24 DOI: 10.5614/j.math.fund.sci.2021.53.2.2

Rusmawan Suwarman, Novitasari Novitasari, I. D. G. A. Junnaedhi

{"title":"A Study on Characteristics and Comparison of Evaporation Estimation Methods in Bandung","authors":"Rusmawan Suwarman, Novitasari Novitasari, I. D. G. A. Junnaedhi","doi":"10.5614/j.math.fund.sci.2021.53.2.2","DOIUrl":"https://doi.org/10.5614/j.math.fund.sci.2021.53.2.2","url":null,"abstract":"This study aims to understand the characteristic of evaporation and to evaluate the evaporation estimation methods to be employed in Bandung by using observation data at three different land cover characteristics sites, namely, densely vegetated area (Baleendah), densely built-up area (Ujung Berung), and mix of buildings and vegetation area (ITB). Observation data used are hourly evaporation, vapour pressure deficit, temperature, relative humidity, wind speed, and radiation. The analysis was done mostly by using statistical methods such as regression analysis and error comparison. The result shows the dominant weather factor affecting the evaporation in ITB and Ujung Berung is vapour pressure deficit, and in Baleendah is solar radiation. The methods of evaporation estimations used in this study are Trabert, Schendel, Turc, and CIMIS-Penman methods. The result shows that the original constant values of those methods are significantly correlated. However, the Schendel is found the most overestimated, and the second is Turc. The best estimated evaporation in Baleendah, ITB, and Ujung Berung is calculated using CIMIS-Penman with one hour lag of radiation, Trabert, and Calibrated Schendel, respectively. The improvement of constant value was applied to Schendel and the result is better than the original constants.","PeriodicalId":16255,"journal":{"name":"Journal of Mathematical and Fundamental Sciences","volume":"40 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77766668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Properties of the Environment of Galaxies in Clusters of Galaxies CL 0024+1654 and RX J0152.7−1357 CL 0024+1654和RX J0152.7−1357星系团中星系环境的性质

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Journal of Mathematical and Fundamental Sciences Pub Date : 2021-06-28 DOI: 10.5614/j.math.fund.sci.2021.53.3.7

P. Premadi, D. Nugroho, A. Jaelani

{"title":"Properties of the Environment of Galaxies in Clusters of Galaxies CL 0024+1654 and RX J0152.7−1357","authors":"P. Premadi, D. Nugroho, A. Jaelani","doi":"10.5614/j.math.fund.sci.2021.53.3.7","DOIUrl":"https://doi.org/10.5614/j.math.fund.sci.2021.53.3.7","url":null,"abstract":"We report the results of combined analyses of X-ray and optical data of two galaxy clusters, CL 0024+1654 and RX J0152.7−1357 at redshift z = 0.395 and z = 0.830, respectively, offering a holistic physical description of the two clusters. Our X-ray analysis yielded temperature and density profiles of the gas in the intra-cluster medium (ICM). Using optical photometric and spectroscopic data, complemented with mass distribution from a gravitational lensing study, we investigated any possible correlation between the physical properties of the galaxy members, i.e. their color, morphology, and star formation rate (SFR), and their environments. We quantified the properties of the environment around each galaxy by galaxy number density, ICM temperature, and mass density. Although our results show that the two clusters exhibit a weaker correlation compared to relaxed clusters, it still confirms the significant effect of the ICM on the SFR in the galaxies. The close relation between the physical properties of galaxies and the condition of their immediate environment found in this work indicates the locality of galaxy evolution, even within a larger bound system such as a cluster. Various physical mechanisms are suggested to explain the relation between the properties of galaxies and their environment.","PeriodicalId":16255,"journal":{"name":"Journal of Mathematical and Fundamental Sciences","volume":"24 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90110520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Graphs of Neighborhood Metric Dimension Two 邻域度量维二的图

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Journal of Mathematical and Fundamental Sciences Pub Date : 2021-06-10 DOI: 10.5614/J.MATH.FUND.SCI.2021.53.1.9

B. Sooryanarayana, Suma Agani Shanmukha

引用次数: 1

Indonesian Micromelum minutum Leave Extracts and Their Cytotoxic Activities toward Breast Cancer Cell Lines 印尼小茴香叶提取物及其对乳腺癌细胞系的细胞毒活性研究

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Journal of Mathematical and Fundamental Sciences Pub Date : 2021-06-07 DOI: 10.5614/J.MATH.FUND.SCI.2021.53.1.8

R. A. Susidarti, E. Meiyanto, Muthi’ Ikawati, Normaidah Normaidah, Nurramadhani A Sida

{"title":"Indonesian Micromelum minutum Leave Extracts and Their Cytotoxic Activities toward Breast Cancer Cell Lines","authors":"R. A. Susidarti, E. Meiyanto, Muthi’ Ikawati, Normaidah Normaidah, Nurramadhani A Sida","doi":"10.5614/J.MATH.FUND.SCI.2021.53.1.8","DOIUrl":"https://doi.org/10.5614/J.MATH.FUND.SCI.2021.53.1.8","url":null,"abstract":"Isolation and identification of compounds and pharmacological activity of Micromelum minutum grown in some countries has been done, but M. minutum from Indonesia has not been studied yet, either phytochemically or pharmacologically. The objective of this study was to determine the cytotoxic activity of Indonesian M. minutum leave extracts toward MCF-7 and 4T1 breast cancer cell lines. The leaves were obtained from M. minutum grown in Bantimurung National Park, Bulusaraung, South Sulawesi. They were macerated gradually in hexane, ethyl acetate, and methanol. The cytotoxic activity of the obtained extracts was determined by MTT assay. The extraction yielded hexane (HEM), ethyl acetate (EEM), and methanol (MEM) extracts of 2.65, 6.12, and 6.49%, respectively. HEM was the most active extract, with IC50 values of 148 and 87 μg/mL on MCF-7 and 4T1 cells, respectively, followed by EEM (185 and 170 μg/mL). MEM possessed weak potency, with an IC50 value of 384 μg/mL on MCF-7 cells, and was not toxic toward 4T1 cells. Therefore, HEM is important to be further investigated for its active constituents.","PeriodicalId":16255,"journal":{"name":"Journal of Mathematical and Fundamental Sciences","volume":"40 1","pages":"109-117"},"PeriodicalIF":0.7,"publicationDate":"2021-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81793720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Microwave-Assisted Claisen-Schmidt Condensation Reaction of Ethyl p-methoxycinnamate to Synthesize p-Methoxystyryl Ketone Derivatives and Evaluate Anti-inflammatory Activity of Synthetic Products 微波辅助clisen - schmidt缩合反应合成对甲氧基苯乙烯酮衍生物及其抗炎活性评价

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Journal of Mathematical and Fundamental Sciences Pub Date : 2021-06-07 DOI: 10.5614/J.FUND.MATH.SCI.2021.53.1.6

Ismiarni Komala, S. Supandi, Nurmeilis Nurmeilis, Yardi Yardi, Ofa Suzanti Betha, N. Indriyani, Moethia Moethia, Muhamad Beny Setiawan, Ghilman Dharmawan, Putri Hayati Nufus, Noni Tri Utami

{"title":"Microwave-Assisted Claisen-Schmidt Condensation Reaction of Ethyl p-methoxycinnamate to Synthesize p-Methoxystyryl Ketone Derivatives and Evaluate Anti-inflammatory Activity of Synthetic Products","authors":"Ismiarni Komala, S. Supandi, Nurmeilis Nurmeilis, Yardi Yardi, Ofa Suzanti Betha, N. Indriyani, Moethia Moethia, Muhamad Beny Setiawan, Ghilman Dharmawan, Putri Hayati Nufus, Noni Tri Utami","doi":"10.5614/J.FUND.MATH.SCI.2021.53.1.6","DOIUrl":"https://doi.org/10.5614/J.FUND.MATH.SCI.2021.53.1.6","url":null,"abstract":"The rhizome of Kaempferia galanga has been known to contain ethyl p-methoxycinnamate (EPMC) (1) as a main component, which has anti-inflammatory properties. Previously we have reported the structural modification of EPMC (1) to form another ester, nitrostyrene, and cinnammamide derivatives and then studied their structure-activity relationships as anti-inflammatory agent. In continuing our research, in this paper, we report the microwave-assisted Claisen-Schmidt condensation of EPMC (1) to synthesize a series of p-methoxystyryl ketones followed by a study of their anti-inflammatory activity. The reaction begins with microwave-assisted cleavage oxidation of hydrolyzed product of EPMC, p-methoxycinnamic acid (2) with Ca(NO3)2 for the synthesis of p-methoxybenzaldehyde (3). Furthermore, 3 was reacted with acetophenone, ethyl methyl ketone and acetone via microwave-assisted Claisen-Schmidt condensation for the synthesis of (E)-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one (5a) (E)-1-(4-methoxyphenyl)pent-1-en-3-one (5b) and (E)-4-(4-methoxyphenyl)but-3-en-2-one (5c), respectively. The reaction products were characterized using spectroscopic techniques and were then tested for anti-inflammatory activity using in vitro anti-denaturation of protein assay. It was found that converting EPMC (1) to 5a and 5b reduced anti-inflammatory activity, while 5c retained anti-denaturation activity with an IC50 of 72.8 µg/ml.","PeriodicalId":16255,"journal":{"name":"Journal of Mathematical and Fundamental Sciences","volume":"9 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90832931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0