Journal of Korean Medical Science最新文献

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Erratum: Correction of Fig. 2 in the Article "Temporal Radiographic Trajectory and Clinical Outcomes in COVID-19 Pneumonia: A Longitudinal Study".
IF 3 3区 医学
Journal of Korean Medical Science Pub Date : 2025-03-31 DOI: 10.3346/jkms.2025.40.e136
Dong-Won Ahn, Yeonju Seo, Taewan Goo, Ji Bong Jeong, Taesung Park, Soon Ho Yoon
{"title":"Erratum: Correction of Fig. 2 in the Article \"Temporal Radiographic Trajectory and Clinical Outcomes in COVID-19 Pneumonia: A Longitudinal Study\".","authors":"Dong-Won Ahn, Yeonju Seo, Taewan Goo, Ji Bong Jeong, Taesung Park, Soon Ho Yoon","doi":"10.3346/jkms.2025.40.e136","DOIUrl":"10.3346/jkms.2025.40.e136","url":null,"abstract":"<p><p>This corrects the article on p. e25 in vol. 40, PMID: 40065711.</p>","PeriodicalId":16249,"journal":{"name":"Journal of Korean Medical Science","volume":"40 12","pages":"e136"},"PeriodicalIF":3.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prediction of 5-Year Survival Rate After Hip Fracture Surgery Using a Comprehensive Geriatric Assessment-Based Frailty Score Model.
IF 3 3区 医学
Journal of Korean Medical Science Pub Date : 2025-03-31 DOI: 10.3346/jkms.2025.40.e40
Jung-Yeon Choi, Jung-Wee Park, Kwang-Il Kim, Young-Kyun Lee, Cheol-Ho Kim
{"title":"Prediction of 5-Year Survival Rate After Hip Fracture Surgery Using a Comprehensive Geriatric Assessment-Based Frailty Score Model.","authors":"Jung-Yeon Choi, Jung-Wee Park, Kwang-Il Kim, Young-Kyun Lee, Cheol-Ho Kim","doi":"10.3346/jkms.2025.40.e40","DOIUrl":"10.3346/jkms.2025.40.e40","url":null,"abstract":"<p><strong>Background: </strong>Hip fractures (HFs) are major osteoporotic injuries associated with morbidity, loss of independence, increased mortality, and an increased socioeconomic burden. The total number of HFs is increasing owing to an aging population. While studies have focused on 30-day or 1-year mortality after HF surgery, studies reporting long-term mortality are lacking. Our study bridges this knowledge gap by exploring the relationship between frailty, postoperative complications, and the 5-year mortality after HF surgery. This study aimed to identify the risk factors associated with 5-year mortality after HF surgery. The impact of the Hip-Multidimensional Frailty Score (Hip-MFS) and postoperative complications on 5-year mortality was compared.</p><p><strong>Methods: </strong>This retrospective study included 536 individuals aged 65 years and older with HFs who underwent surgery between 2009 and 2014. The Hip-MFS was calculated using the comprehensive geriatric assessment. Patients whose Hip-MFS score above 8 considered as frail. Postoperative complications included pneumonia, urinary tract infection, delirium, pulmonary thromboembolism, and unplanned intensive care unit admission after surgery. The primary outcome was 5-year mortality. Univariate and multivariate cox-regression, Kaplan-Meier analysis and log-rank tests were used to assess predictive value of frailty and postoperative complications on 5-year mortality.</p><p><strong>Results: </strong>The mean age was 80.5 ± 7.0 years and 71.3% (n = 382) were women. Overall, 48.3% (n = 259) were diagnosed with femoral neck fractures, and 51.7% (n = 277) were diagnosed with intertrochanteric fractures. A total of 223 (41.6%) patients experienced postoperative complications. The overall mortality rate was 60.4% (n = 324), with 1-year and 5-year mortality rates after HF surgery being 13.8% (n = 74) and 43.8% (n = 235), respectively. In the multivariate regression analysis, after adjusting for clinical and demographic factors, the high-risk Hip-MFS group and the group with postoperative complications had hazard ratios for 5-year survival of 1.513 (95% confidence interval [CI], 1.105-2.017; <i>P</i> = 0.010) and 1.470 (95% CI, 1.117-1.936; <i>P</i> = 0.006), respectively. Patients who had postoperative complications with a low Hip-MFS showed better 5-year survival than those without postoperative complications with a high Hip-MFS in the Kaplan-Meier curve (<i>P</i> = 0.013).</p><p><strong>Conclusion: </strong>A high Hip-MFS risk and postoperative complications were associated with an increased 5-year mortality rate. In comparison to the occurrence of postoperative complications, the frailty status evaluated using the Hip-MFS had a more significant impact on long-term mortality after HF surgery.</p>","PeriodicalId":16249,"journal":{"name":"Journal of Korean Medical Science","volume":"40 12","pages":"e40"},"PeriodicalIF":3.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation Between the Distance From Donors and Ischemic Time in Heart Transplantation of Korea and Its Clinical Impact.
IF 3 3区 医学
Journal of Korean Medical Science Pub Date : 2025-03-24 DOI: 10.3346/jkms.2025.40.e60
Jung Yeon Jin, Chee-Hoon Lee, Mi Hee Lim, Soo Yong Lee, Min Ho Ju, Hyung Gon Je
{"title":"Correlation Between the Distance From Donors and Ischemic Time in Heart Transplantation of Korea and Its Clinical Impact.","authors":"Jung Yeon Jin, Chee-Hoon Lee, Mi Hee Lim, Soo Yong Lee, Min Ho Ju, Hyung Gon Je","doi":"10.3346/jkms.2025.40.e60","DOIUrl":"10.3346/jkms.2025.40.e60","url":null,"abstract":"<p><strong>Background: </strong>The heart donor allocation system in South Korea is divided into three regions, with priority given to recipients within the same region over those in other regions of the same tier. It is commonly believed that heart transplantation (HT) within the same region can reduce ischemic time (IT), although its clinical impact remains unclear. The purpose of this study is to compare the characteristics and outcomes of intra-region HT and inter-region HT.</p><p><strong>Methods: </strong>From 2014 to 2022, a total of 115 adult patients underwent isolated HT at a tertiary hospital. Of these, 58 recipients (54.5 ± 10.3 years, female, 36.2%) underwent intra-region HT and 57 recipients (53.9 ± 14.1 years, female, 31.6%) underwent inter-region HT. Extracorporeal membrane oxygenation-bridged HTs accounted for 50.0% and 54.4% of cases, respectively (<i>P</i> = 0.638). There were no differences in preoperative characteristics between the two groups.</p><p><strong>Results: </strong>The median inter-hospital distance (38.0 [32.0-112.0] km vs. 351.0 [300.0-390.5] km, <i>P</i> < 0.001) and total IT (153 [123-170] minute vs. 265 [243-298] minute, <i>P</i> < 0.001) were longer in the inter-region group than intra-region group. Despite these differences, both groups showed similar clinical outcomes. The 30-day mortality rates were 5.2% and 5.3% (<i>P</i> < 0.99), respectively. There were no differences in postoperative cardiac index, early adverse outcomes, or long-term survival between the two groups. The inter-hospital distance and cold IT showed a strong positive correlation (time [minute] = 39.462 + 0.410 × distance [km]).</p><p><strong>Conclusion: </strong>Despite the difference in IT, there was no difference in postoperative outcomes between the two groups. Based on these findings, the effect of donor location on the outcomes of HT in South Korea is not considered significant.</p>","PeriodicalId":16249,"journal":{"name":"Journal of Korean Medical Science","volume":"40 11","pages":"e60"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence and Temporal Dynamics of Combined Infections in SARS-CoV-2-Infected Patients With Risk Factors for Severe Complications.
IF 3 3区 医学
Journal of Korean Medical Science Pub Date : 2025-03-24 DOI: 10.3346/jkms.2025.40.e38
Sin Young Ham, Seungjae Lee, Min-Kyung Kim, Jaehyun Jeon, Eunyoung Lee, Subin Kim, Jae-Phil Choi, Hee-Chang Jang, Sang-Won Park
{"title":"Incidence and Temporal Dynamics of Combined Infections in SARS-CoV-2-Infected Patients With Risk Factors for Severe Complications.","authors":"Sin Young Ham, Seungjae Lee, Min-Kyung Kim, Jaehyun Jeon, Eunyoung Lee, Subin Kim, Jae-Phil Choi, Hee-Chang Jang, Sang-Won Park","doi":"10.3346/jkms.2025.40.e38","DOIUrl":"10.3346/jkms.2025.40.e38","url":null,"abstract":"<p><strong>Background: </strong>Coronavirus disease 2019 (COVID-19) is a newly emerged infectious disease that needs further clinical investigation. Characterizing the temporal pattern of combined infections in patients with COVID-19 may help clinicians understand the clinical nature of this disease and provide valuable diagnostic and therapeutic guidelines.</p><p><strong>Methods: </strong>We retrospectively analyzed COVID-19 patients isolated in four study hospitals in Korea for one year period from May 2021 to April 2022 when the delta and omicron variants were dominant. The temporal characteristics of combined infections based on specific diagnostic tests were analyzed.</p><p><strong>Results: </strong>A total of 16,967 COVID-19 patients were screened, 2,432 (14.3%) of whom underwent diagnostic microbiologic tests according to the clinical decision-making, 195 of whom had positive test results, and 0.55% (94/16,967) of whom were ultimately considered to have clinically meaningful combined infections. The median duration for the diagnosis of combined infections was 15 (interquartile range [IQR], 5-25) days after admission. The proportion of community-acquired coinfections (≤ 2 days after admission) was 11.7% (11/94), which included bacteremia (10/94, 10.63%) and tuberculosis (1/94, 1.06%). Combined infections after 2 days of admission were diagnosed at median 16 (IQR, 9-26) days, and included bacteremia (72.3%), fungemia (19.3%), cytomegalovirus (CMV) diseases (8.4%), <i>Pneumocystis jerovecii</i> pneumonia (PJP, 8.4%) and invasive pulmonary aspergillosis (IPA, 4.8%).</p><p><strong>Conclusion: </strong>Among COVID-19 patients with risk factors for severe complications, 0.55% had laboratory-confirmed combined infections, which included community and nosocomial pathogens in addition to unusual pathogens such as CMV disease, PJP and IPA.</p>","PeriodicalId":16249,"journal":{"name":"Journal of Korean Medical Science","volume":"40 11","pages":"e38"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In This Issue on 24-March-2025.
IF 3 3区 医学
Journal of Korean Medical Science Pub Date : 2025-03-24 DOI: 10.3346/jkms.2025.40.e126
Jin-Hong Yoo
{"title":"In This Issue on 24-March-2025.","authors":"Jin-Hong Yoo","doi":"10.3346/jkms.2025.40.e126","DOIUrl":"https://doi.org/10.3346/jkms.2025.40.e126","url":null,"abstract":"","PeriodicalId":16249,"journal":{"name":"Journal of Korean Medical Science","volume":"40 11","pages":"e126"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Different Patterns of the Relationship Between Gynecological Malignancy and Obesity Index: A Nationwide Retrospective Cohort Study in Korea.
IF 3 3区 医学
Journal of Korean Medical Science Pub Date : 2025-03-24 DOI: 10.3346/jkms.2025.40.e31
Seo Young Kang, Ye-Jee Kim, Sehee Kim, Hye Soon Park
{"title":"Different Patterns of the Relationship Between Gynecological Malignancy and Obesity Index: A Nationwide Retrospective Cohort Study in Korea.","authors":"Seo Young Kang, Ye-Jee Kim, Sehee Kim, Hye Soon Park","doi":"10.3346/jkms.2025.40.e31","DOIUrl":"10.3346/jkms.2025.40.e31","url":null,"abstract":"<p><strong>Background: </strong>In Korea, the patterns of prevalence of gynecological cancers have shifted due to rising obesity-related cancer cases. We evaluated the associations of body mass index (BMI) and waist circumference (WC) with the risk of gynecological malignancy in Korean women.</p><p><strong>Methods: </strong>Using National Health Insurance Service cohort data, we analyzed 365,581 participants among the 1,999,980 women aged ≥ 19 years who underwent health check-ups at the baseline year 2009-2010, excluding those who died, those with prior cancer diagnoses, underwent hysterectomy and/or salpingo-oophorectomy before the index date (January 1st, 2011), or missing/outliers BMI and WC values. Follow-up extended to December 31st, 2021, evaluating the incidences of endometrial, ovarian, and cervical cancer. The hazard ratios (HRs) and 95% confidence intervals (CIs) for each gynecological malignancy according to BMI and WC were calculated using Cox proportional hazard regression.</p><p><strong>Results: </strong>Among the 365,581 participants, 898, 1,268, and 873 cases of endometrial, ovarian, and cervical cancer occurred, respectively. HRs (95% CIs) for endometrial cancer were 1.37 (1.15-1.63), 1.63 (1.38-1.94), and 3.64 (2.81-4.70) for BMIs of 23.0-24.9, 25.0-29.9, and ≥ 30 kg/m² compared to BMI of 18.5-22.9 kg/m² (<i>P</i> for trend < 0.001). HRs (95% CIs) for ovarian cancer were 1.16 (1.00-1.33), 1.19 (1.03-1.37), and 1.49 (1.12-1.98) for BMIs of 23.0-24.9, 25.0-29.9, and ≥ 30 kg/m² compared to BMI of 18.5-22.9 kg/m² (<i>P</i> for trend = 0.002). No significant association was found between BMI and the risk for cervical cancer (<i>P</i> for trend = 0.266). HRs (95% CIs) for endometrial cancer were 1.35 (1.09-1.66), 1.41 (1.14-1.74), and 1.90 (1.55-2.34) for the 2nd, 3rd, and 4th quartiles of WCs compared to the 1st quartile (<i>P</i> for trend <0.001). Ovarian cancer tended to increase and cervical cancer tended to decrease as WC increased (<i>P</i> for trend = 0.035 for ovarian cancer, <i>P</i> for trend = 0.034 for cervical cancer).</p><p><strong>Conclusion: </strong>In Korean women, the risks of endometrial and ovarian cancers increased significantly from the pre-obese level as BMI and WC increased, while cervical cancer risk tended to increase as WC decreased. Management of obesity should be reinforced for the prevention of obesity-related gynecological cancers, considering the increasing incidence of these cancers among Korean women.</p>","PeriodicalId":16249,"journal":{"name":"Journal of Korean Medical Science","volume":"40 11","pages":"e31"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global Burden of Vaccine-Associated Cerebrovascular Venous Sinus Thrombosis, 1968-2024: A Critical Analysis From the WHO Global Pharmacovigilance Database.
IF 3 3区 医学
Journal of Korean Medical Science Pub Date : 2025-03-24 DOI: 10.3346/jkms.2025.40.e101
Jaehyeong Cho, Hyesu Jo, Hyunjee Kim, Jaeyu Park, Damiano Pizzol, Min Seo Kim, Ho Geol Woo, Dong Keon Yon
{"title":"Global Burden of Vaccine-Associated Cerebrovascular Venous Sinus Thrombosis, 1968-2024: A Critical Analysis From the WHO Global Pharmacovigilance Database.","authors":"Jaehyeong Cho, Hyesu Jo, Hyunjee Kim, Jaeyu Park, Damiano Pizzol, Min Seo Kim, Ho Geol Woo, Dong Keon Yon","doi":"10.3346/jkms.2025.40.e101","DOIUrl":"10.3346/jkms.2025.40.e101","url":null,"abstract":"<p><p>Despite widespread coronavirus disease 2019 (COVID-19) vaccine use, research on the association between vaccines and cerebrovascular venous sinus thrombosis (CVST) in diverse populations is limited. This study aimed to address this gap. Data from the World Health Organization pharmacovigilance database (1968-2024; total reports = 8,909,484) were used. Reporting odds ratios (RORs) and information components (ICs) were calculated to assess the association between each drug and CVST. In total, 851 cases were identified as vaccine-associated CVST, of which 527 (61.93%) occurred in female patients. Only Ad5-vectored COVID-19 vaccines had the highest ROR and IC value with CVST (ROR, 4.78; 95% confidence interval, 4.34-5.28; IC, 2.15). The risk of CVST increased with age, with the 45-64-years age group having an IC of 1.35, while the 65 years and older group had a higher IC of 2.08. The findings highlight the need for clinicians to recognize the potential risks of CVST and prioritize rigorous monitoring and research to ensure patient safety.</p>","PeriodicalId":16249,"journal":{"name":"Journal of Korean Medical Science","volume":"40 11","pages":"e101"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Explainability Enhanced Machine Learning Model for Classifying Intellectual Disability and Attention-Deficit/Hyperactivity Disorder With Psychological Test Reports.
IF 3 3区 医学
Journal of Korean Medical Science Pub Date : 2025-03-24 DOI: 10.3346/jkms.2025.40.e26
Tong Min Kim, Young-Hoon Kim, Sung-Hee Song, In-Young Choi, Dai-Jin Kim, Taehoon Ko
{"title":"Explainability Enhanced Machine Learning Model for Classifying Intellectual Disability and Attention-Deficit/Hyperactivity Disorder With Psychological Test Reports.","authors":"Tong Min Kim, Young-Hoon Kim, Sung-Hee Song, In-Young Choi, Dai-Jin Kim, Taehoon Ko","doi":"10.3346/jkms.2025.40.e26","DOIUrl":"10.3346/jkms.2025.40.e26","url":null,"abstract":"<p><strong>Background: </strong>Psychological test reports are essential in assessing intellectual functioning, aiding in diagnosing and treating intellectual disability (ID) and attention-deficit/hyperactivity disorder (ADHD). However, these reports can have several problems because they are diverse, unstructured, subjective, and involve human errors. Additionally, physicians often do not read the entire report, and the number of reports is lower than that of diagnoses.</p><p><strong>Methods: </strong>We developed explainable predictive models for classifying IDs and ADHDs based on written reports to address these issues. The reports of 1,475 patients with IDs and ADHDs who underwent intelligence tests were used for the models. These models were developed by analyzing reports using natural language processing (NLP) and incorporating the physician's diagnosis for each report. We selected n-gram features from the models' results by extracting important features using SHapley Additive exPlanations and permutation importance to make the models explainable. Developing the n-gram feature-based original text search system compensated for the lack of human readability caused by NLP and enabled the reconstruction of human-readable texts from the selected n-gram features.</p><p><strong>Results: </strong>The maximum model accuracy was 0.92, and the 80 human-readable texts were restored from four models.</p><p><strong>Conclusion: </strong>The results showed that the models could accurately classify IDs and ADHDs, even with a few reports. The models were also able to explain their predictions. The explainability-enhanced model can help physicians understand the classification process of IDs and ADHDs and provide evidence-based insights.</p>","PeriodicalId":16249,"journal":{"name":"Journal of Korean Medical Science","volume":"40 11","pages":"e26"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of the Phoenix Criteria for Sepsis and Septic Shock in a Pediatric Intensive Care Unit.
IF 3 3区 医学
Journal of Korean Medical Science Pub Date : 2025-03-17 DOI: 10.3346/jkms.2025.40.e106
Chang Hoon Han, Hamin Kim, Mireu Park, Soo Yeon Kim, Jong Deok Kim, Myung Hyun Sohn, Seng Chan You, Kyung Won Kim
{"title":"Validation of the Phoenix Criteria for Sepsis and Septic Shock in a Pediatric Intensive Care Unit.","authors":"Chang Hoon Han, Hamin Kim, Mireu Park, Soo Yeon Kim, Jong Deok Kim, Myung Hyun Sohn, Seng Chan You, Kyung Won Kim","doi":"10.3346/jkms.2025.40.e106","DOIUrl":"10.3346/jkms.2025.40.e106","url":null,"abstract":"<p><p>The applicability of the Phoenix criteria and Phoenix Sepsis Score in higher-resource pediatric intensive care units (PICUs) outside the United States requires further validation. A retrospective cohort study analyzed electronic health records of 1,304 PICU admissions under 18 years old with suspected infection between February 2017 and December 2023. The score was calculated using two methods: 24-hour assessment, based on worst sub-scores within 24 hours of admission, and prompt assessment, using values closest to admission within 6 hours before or after. Based on the 24-hour assessment, in-hospital mortality was 8.3% for sepsis and 10.3% for septic shock. The score demonstrated an area under the precision-recall curve of 0.42 (95% confidence interval, 0.31-0.55) for in-hospital mortality. Results were consistent across both assessment methods. The Phoenix criteria and the Phoenix Sepsis Score are reliable predictors of mortality outcomes. Further investigation in diverse clinical settings is warranted.</p>","PeriodicalId":16249,"journal":{"name":"Journal of Korean Medical Science","volume":"40 10","pages":"e106"},"PeriodicalIF":3.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strategies for Monitoring and Supporting Living Donors in Korea: An Expert Position Paper.
IF 3 3区 医学
Journal of Korean Medical Science Pub Date : 2025-03-17 DOI: 10.3346/jkms.2025.40.e33
Eunjeong Kang, Hye Young Woo, Su Young Hong, Hajeong Lee, Sangil Min, Jongwon Ha
{"title":"Strategies for Monitoring and Supporting Living Donors in Korea: An Expert Position Paper.","authors":"Eunjeong Kang, Hye Young Woo, Su Young Hong, Hajeong Lee, Sangil Min, Jongwon Ha","doi":"10.3346/jkms.2025.40.e33","DOIUrl":"10.3346/jkms.2025.40.e33","url":null,"abstract":"<p><strong>Background: </strong>The number of organ transplants in South Korea has increased, with a notable rise in living donor transplants. Ensuring their long-term health and well-being is critical to address potential complications and maintain the success of the transplant programs.</p><p><strong>Methods: </strong>A diverse advisory panel, including transplant experts and coordinators, was established to evaluate the follow-up care for living donors. The panel reviewed the results of a brief survey of donors regarding their donation experience, follow-up programs, guidelines, and policies from South Korea and other countries, aiming to identify best practices and recommend improvements.</p><p><strong>Results: </strong>The study found that follow-up care for living donors in South Korea is inconsistent and lacks standardization. Significant variability exists in follow-up practices across different institutions, and comprehensive data on donor health pre- and post-donation are scarce. The need for continuous, systematic follow-up, encompassing both medical and psychological support, is emphasized to ensure donor well-being.</p><p><strong>Conclusion: </strong>Improving follow-up care for living donors is essential. Establishing a national registry and increasing donor advocacy teams are meaningful steps to enhance donor care, ensure long-term health, and maintain ethical standards in organ donation.</p>","PeriodicalId":16249,"journal":{"name":"Journal of Korean Medical Science","volume":"40 10","pages":"e33"},"PeriodicalIF":3.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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