Journal of Kermanshah University of Medical Sciences最新文献_第4页

Herpes Simplex Infection in Cardiovascular Disease (CVD) Patients: A Seroepidemiological Study 心血管疾病(CVD)患者的单纯疱疹感染:一项血清流行病学研究

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-03-14 DOI: 10.5812/jkums-135233

Samaneh Abolbashari, Ehsan Seydali Seyf Abad, E. Aryan, Toktam Dehghani, M. Moohebati, Majid Ghayour Mobarhan, Z. Meshkat, M. Meshkat, Amin Hooshyar Chechaklou, M. Khoshakhlagh, A. Gholoubi

{"title":"Herpes Simplex Infection in Cardiovascular Disease (CVD) Patients: A Seroepidemiological Study","authors":"Samaneh Abolbashari, Ehsan Seydali Seyf Abad, E. Aryan, Toktam Dehghani, M. Moohebati, Majid Ghayour Mobarhan, Z. Meshkat, M. Meshkat, Amin Hooshyar Chechaklou, M. Khoshakhlagh, A. Gholoubi","doi":"10.5812/jkums-135233","DOIUrl":"https://doi.org/10.5812/jkums-135233","url":null,"abstract":"Background: Herpes simplex viruses have been implicated as a cause of cardiovascular disease (CVD) due to their widespread distribution and ability to infect human vascular endothelial cells. Objectives: The present study aimed to evaluate the link between Herpes simplex infections and cardiovascular disease. Methods: This case-control study involved 236 patients aged 35 - 65, 118 with known cardiovascular disease and 118 controls. Patients’ cardiovascular disease evaluation was based on data from questionnaires, a specialist’s physical examinations, and paraclinical tests. Herpes simplex viruses (HSV)-antibodies (IgM, IgG) were determined using ELISA in serum samples, and the biochemical blood indicators were analyzed to examine their relationship to the level of HSV antibodies. All the data were analyzed using SPSS software version 20. Results: IgM antibodies against herpes simplex were negative among all 236 patients. The positivity rate of IgG antibodies against herpes simplex was 58.8 and 51.2% in the case and control groups, respectively with no significant difference (P = 0.253). Patients with cardiovascular disease had a 0.587-fold higher positive rate of IgG antibodies than patients in the control group (odds ratio (OR) = 0.587). The mean age of patients with positive IgG antibodies was significantly lower than patients with negative IgG antibodies (P = 0.012). IgG positivity among men and women (P = 0.670) and different job statuses (P = 0.866) were not significantly different. Conclusions: The positivity rate of IgG antibodies against herpes simplex was not significantly different among the study groups. Although patients with positive IgG antibodies’ mean age was lower than those with negative IgG antibodies, the gender and job status were not different.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"84 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89411984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Strawberry Extract Supplementation on Caspase -3 and Cytochrome c after Resistance Exercise in Non-Athletic Women 补充草莓提取物对非运动女性抗阻运动后Caspase -3和细胞色素c的影响

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-03-09 DOI: 10.5812/jkums-126940

M. R. Rahimi, H. Faraji, Somayeh Ravosh

{"title":"The Effect of Strawberry Extract Supplementation on Caspase -3 and Cytochrome c after Resistance Exercise in Non-Athletic Women","authors":"M. R. Rahimi, H. Faraji, Somayeh Ravosh","doi":"10.5812/jkums-126940","DOIUrl":"https://doi.org/10.5812/jkums-126940","url":null,"abstract":"Background: Exercise-induced apoptosis occurs in a variety of tissues. Objectives: This study aimed to determine the effects of strawberry extract supplementation on circulating apoptosis biomarkers following a single bout of resistance exercise. Methods: Eighteen healthy young untrained women were enrolled in a randomized, double-blind, placebo-controlled crossover research. The subjects participated in one resistance exercise session (at 80% 1RM) and underwent 2wk strawberry extracts (700 mg daily) or maltodextrin. The washout period that separated the treatment periods was 4wk. Blood samples were taken before supplementation and after 2 w of the post-resistance exercise session to determine cytochrome c and caspase-3 serum markers. Results: Resting cytochrome c and caspase-3 concentrations were not significantly different for any strawberry extract supplementation and placebo groups (P > 0.05). Cytochrome c and caspase-3 were significantly elevated after exercise in a placebo (P < 0.05) but not strawberry extract supplementation. Conclusions: Supplementation with strawberry extract attenuates intense acute exercise-induced apoptosis in healthy women.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84895735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Combined Aerobic-Resistance and Aerobic Training on Heart Systolic Function in Heart Failure Patients after Coronary Artery Bypass Graft Surgery (CABG) 有氧-阻力联合训练与有氧训练对冠状动脉搭桥术后心力衰竭患者心脏收缩功能的影响

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-03-04 DOI: 10.5812/jkums-128953

Mohammad Sobhan Amiripour, Asadollah Amiripour, Siroos Nasiri, Sepideh Omidi, Farshid Raisi

{"title":"Comparison of Combined Aerobic-Resistance and Aerobic Training on Heart Systolic Function in Heart Failure Patients after Coronary Artery Bypass Graft Surgery (CABG)","authors":"Mohammad Sobhan Amiripour, Asadollah Amiripour, Siroos Nasiri, Sepideh Omidi, Farshid Raisi","doi":"10.5812/jkums-128953","DOIUrl":"https://doi.org/10.5812/jkums-128953","url":null,"abstract":"Background: Heart disease is the most common cause of mortality worldwide, and heart surgery frequently occurs. The results are strongly dependent on lifestyle modification and especially sports exercises. Objectives: In this study, aimed to compare the effect of eight weeks of aerobic and combined training on systolic cardiac function in heart failure patients after coronary artery bypass surgery. Methods: In this randomized clinical trial, 30 cardiac patients under CABG surgery at Kermanshah Heart Center were randomly divided into three groups, control, combined, and aerobic training. The protocols of the combined group included two movements of the upper limbs (pectoralis major and deltoid muscles) and two movements of the lower limbs (quadriceps and hamstring muscles) by three sets/10Rep and aerobic group with 60 - 85-minute exercises at 70 - 85% peak HR in three sessions per week for eight weeks. The collected data were analyzed using the SPSS software version 22, One-way ANOVA, and Tukey tests; P < 0.05 was considered significant. Results: After eight weeks, Systolic heart function wasn’t increased in the control group (P > 0.05) but was raised in the aerobic and combined training groups (P = 0.0001). There was no significant difference between in two intervention groups (P > 0.05). Conclusions: Aerobic and combined exercises positively affect systolic cardiac function after coronary artery bypass surgery. Therefore, doing both exercises in these patients is recommended.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86850519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survivor’s Experiences of Psychological Challenges in COVID-19 Patients: An Internet-based Phenomenological Study COVID-19患者心理挑战的幸存者经历:基于互联网的现象学研究

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-02-19 DOI: 10.5812/jkums133149

Milad Jalilian, R. Jalali, L. Menati

{"title":"Survivor’s Experiences of Psychological Challenges in COVID-19 Patients: An Internet-based Phenomenological Study","authors":"Milad Jalilian, R. Jalali, L. Menati","doi":"10.5812/jkums133149","DOIUrl":"https://doi.org/10.5812/jkums133149","url":null,"abstract":"Background: Confirmed and suspected patients with SARS-CoV-2 may fear contagion to others and the severe consequences of the disease. Therefore, they may feel loneliness, denial, anxiety, depression, insomnia, and hopelessness, reducing treatment adherence. Objectives: This study aimed to discuss the psychological challenges of survivors’ experiences in SARS-CoV-2 infection. Methods: This descriptive phenomenological study explored survivors’ experiences of COVID-19 infection. Validated websites’ stories and notes were used to collect data. The stories were transcribed and analyzed by Colaizzi’s phenomenological analysis method. The authors screened the transcribed texts, extracted and summarized meaningful statements, and reported the themes independently. In addition, six criteria of authority, accuracy, objectivity, currency, coverage, and appearance were considered for evaluating web page quality. The data were analyzed using MAXQDA 10 software. Results: A total of 45 patients’ stories with COVID-19 were analyzed. Four general themes and 11 sub-themes were extracted via reading stories and extracting themes, including stigma (the sub-themes of embarrassment, defame, and Hopelessness), horror (sub-themes of denial, not professional experience, and toward death), different lifestyles (the sub-themes of change, unfriended, and sleeplessness), and freedom (two sub-themes of calmness and Rescue). Conclusions: Based on the studies, the participants reported high rates of symptoms of fear, change, insomnia, and horror. Supporting COVID-19 patients in these critical conditions is one of the essential components of acute care measures. Specific interventions to promote mental health in exposed patients should be applied immediately and require special attention.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82068576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Plasmid Mediated Colistin Resistance in Colistin Resistant Gram-negative Bacilli 耐粘菌素革兰氏阴性杆菌质粒介导的粘菌素耐药性评价

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-02-17 DOI: 10.5812/jkums-132351

Y. Tanrıverdi Çaycı, Kubra Hacieminoglu Ulker, Demet Gur Vural, K. Bilgin, A. Birinci

{"title":"Evaluation of Plasmid Mediated Colistin Resistance in Colistin Resistant Gram-negative Bacilli","authors":"Y. Tanrıverdi Çaycı, Kubra Hacieminoglu Ulker, Demet Gur Vural, K. Bilgin, A. Birinci","doi":"10.5812/jkums-132351","DOIUrl":"https://doi.org/10.5812/jkums-132351","url":null,"abstract":"Background: Infections caused by carbapenem-resistant gram-negative bacteria are treated with colonistin as a last resort. However, the increased resistance in recent years is significant for treating multiple drug-resistant infections. Objectives: This study aimed to determine the resistance genes mobile colistin resistance (mcr)-1 and mcr-2 in the colistin-resistant isolates, understand the resistance mechanism, and help with treatment. Methods: Isolates were identified in the Vitek MS automated system. The antibiotic susceptibility was tested with the Vitek 2 Compact automated system. Enteric gram-negative bacilli isolates were stored at -20°C until the molecular study. DNA extraction of colistin-resistant isolates was performed by boiling method. Then, polymerase chain reaction (PCR) optimization was performed using the specific primers, and mcr-1 and mcr-2 genes were investigated by the multiplex PCR method. Results: About 170 enteric gram-negative bacilli isolate were mainly sent from internal medicine (44.7%) and neurology (13.5%) services. According to the species identification, 37.6% of the isolates were Klebsiella pneumonia, and 31.7% were Serratia marcescens. Based on PCR results, mcr-1 and mcr-2 genes were not detected in the isolates. Conclusions: Increased colistin resistance and the worrying discovery of mcr genes require urgent precautions, even though the study did not detect mcr-1 and mcr-2. New studies investigating mcr genes in new isolates are needed to understand the mechanism of resistance and identify resistant isolates.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"1047 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77233736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Characteristics of Breast Cancer Patients and Survival Analysis in the Southeast of Iran: A Retrospective Cohort Study 伊朗东南部乳腺癌患者的特征和生存分析:一项回顾性队列研究

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-02-12 DOI: 10.5812/jkums-133836

M. Larizadeh, A. Nemati, M. Aryaie, A. Naghibzadeh-Tahami

{"title":"The Characteristics of Breast Cancer Patients and Survival Analysis in the Southeast of Iran: A Retrospective Cohort Study","authors":"M. Larizadeh, A. Nemati, M. Aryaie, A. Naghibzadeh-Tahami","doi":"10.5812/jkums-133836","DOIUrl":"https://doi.org/10.5812/jkums-133836","url":null,"abstract":"Background: Breast cancer is the most common cancer in women, with different survival rates depending on the patients’ characteristics. Objectives: This study aimed to evaluate breast cancer patients’ characteristics and survival rates in the southeast of Iran. Methods: The recorded data of breast cancer patients treated were collected from 2004 to 2020 in the Radiation Oncology Department of Kerman University of Medical Sciences, Iran. Overall survival (OS) was estimated using the Kaplan-Meier method. The log-rank test was used to compare OS based on various factors. Three modeling strategies were considered to examine the patients’ survival using multiple Cox regression models. Results: The study included 309 patients who met the inclusion criteria; 153 (49.5%) were under 51 years of age. Luminal A intrinsic subtype accounted for 18.8% of cancer patients. Five- and 10-year OS rates were 86% and 63%, respectively. Five- and 10-year disease-free survival (DFS) rates for nonmetastatic patients were 82% and 60%, respectively. Multiple Cox regression showed that the percentage of the involved dissected lymph nodes, group stage, T-stage, M-stage, locoregional recurrence, and luminal subtype were independent prognostic factors for survival. Conclusions: Based on the results, the percentage of breast cancer patients under 50 years old is higher in the southeast of Iran compared to Western countries. In addition, the prevalence of the luminal A subtype is lower than in other regions. The survival results were consistent with other studies.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90309603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Branch Retinal Vein Occlusion Occurring After 2nd Dose of Sinopharm COVID-19 Vaccine: A Case Report 国药新冠肺炎疫苗第二次接种后发生视网膜分支静脉闭塞1例

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-02-08 DOI: 10.5812/jkums-129793

Leyla Rezaei

引用次数: 1

Illness Perception and Coping Strategies on the Perceived Quality of Life in Adults with Coronary Heart Diseases: A Model Evaluation 疾病认知和应对策略对成年冠心病患者感知生活质量的影响:模型评价

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-02-02 DOI: 10.5812/jkums-133313

M. Bagheri, M. Farahani, H. Hasanabadi, Balal Izanloo

{"title":"Illness Perception and Coping Strategies on the Perceived Quality of Life in Adults with Coronary Heart Diseases: A Model Evaluation","authors":"M. Bagheri, M. Farahani, H. Hasanabadi, Balal Izanloo","doi":"10.5812/jkums-133313","DOIUrl":"https://doi.org/10.5812/jkums-133313","url":null,"abstract":"Background: Patients' perceptions of illness can influence their compliance with medical recommendations and, consequently, their perceived quality of life. Objectives: This study aimed to evaluate illness perception in patients diagnosed with coronary heart disease (CHD). Methods: This cross-sectional correlational study was conducted on 300 individuals with CHD, who were selected from the specialized heart clinics affiliated with Mazandaran University of Medical Sciences in 2018 using the convenient method. The researcher used the brief illness perception questionnaire (B-IPQ), the coping schemas inventory (CSI), and a 3-item questionnaire (designed by the researcher) to collect data. The Data were analyzed by the Structural Equation Modeling Modeling (path analysis) in LISREL based on the Maximum Likelihood Estimation (MLE) at P < 0.01 and P < 0.05. Results: A total of 60% of the individuals aged between 30 to 65, including 60.3% male and 39.7% female. Based on the research model, paths of coping strategies directly affected the perceived quality of life. Illness cognition directly impacts coping strategies and indirectly affects the perceived quality of life through the mediating role of managing strategies. Based on the evaluation of SRMI, perceived quality of life can be predictive through coping strategies and illness cognition. Conclusions: Based on the results, patients should be informed about their illness’s cognitive components and adaptive coping strategies, including situational coping strategies, coping by social support, acceptance, and active emotional expression coping to improve their quality of life.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88484405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of a Multiple Dentoalveolar Trauma in Permanent Teeth: A Case Report with an 18-Month Follow-up 恒牙多发牙槽外伤的治疗:1例随访18个月

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-01-22 DOI: 10.5812/jkums-129134

Arghavan Kamali Sabeti, Shaghayegh Golshani, Parisa Vahedi

引用次数: 0

Evaluation of Molecular Docking and Cytotoxicity by Pycnocycla bashagardiana Fruit Essential Oil in Colon Cancer Cell Lines

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-01-19 DOI: 10.5812/jkums-131043

Zahra Ghazazani, M. Heshmati, J. Asgarpanah, Sanaz Pashapour

{"title":"Evaluation of Molecular Docking and Cytotoxicity by Pycnocycla bashagardiana Fruit Essential Oil in Colon Cancer Cell Lines","authors":"Zahra Ghazazani, M. Heshmati, J. Asgarpanah, Sanaz Pashapour","doi":"10.5812/jkums-131043","DOIUrl":"https://doi.org/10.5812/jkums-131043","url":null,"abstract":"Background: Pycnocycla bashagardiana essential oil (EO) is extracted from fruits via hydrodistillation and analyzed through gas chromatography-mass spectrometry. Objectives: This study aimed to evaluate molecular docking and cytotoxicity by P. bashagardiana EO in colon cancer cell lines. Methods: The viability rates of P. bashagardiana fruit essential oil (PBFEO)-treated normal L929 and HT29 cancer cells were assessed at 0 - 500 μg/mL in 24 and 48 h by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide. The cell apoptosis percentage was investigated via flow cytometry and gene expression of BAX and BCL2 using the real-time polymerase chain reaction. In addition, the efficient myristicin binding was examined with the BCL2 protein through molecular docking analysis. Results: The half maximal inhibitory concentrations of 431.8 and 450 μg/mL in L929 cells, as well as 278.5 and 144.6 μg/mL in HT29 cells, were recorded at 24 and 48 h, respectively. The cell apoptosis percentage was examined by annexin-V-FITC. The results indicated a significant increase in the apoptosis percentage. A significant increase was also observed in HT29 cancer cells compared to normal L929 cells regarding the expression ratio of BAX/BCL2 genes. Myristicin’s binding affinity to BCL2 was relatively weak compared to the control. Conclusions: Based on the results, myristicin can be suggested as a complementary treatment for colon cancer through more effective treatment and reducing the side effects of normal cells.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"446 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76350824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4