The Effect of Strawberry Extract Supplementation on Caspase -3 and Cytochrome c after Resistance Exercise in Non-Athletic Women

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-03-09 DOI:10.5812/jkums-126940

M. R. Rahimi, H. Faraji, Somayeh Ravosh

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Abstract

Background: Exercise-induced apoptosis occurs in a variety of tissues. Objectives: This study aimed to determine the effects of strawberry extract supplementation on circulating apoptosis biomarkers following a single bout of resistance exercise. Methods: Eighteen healthy young untrained women were enrolled in a randomized, double-blind, placebo-controlled crossover research. The subjects participated in one resistance exercise session (at 80% 1RM) and underwent 2wk strawberry extracts (700 mg daily) or maltodextrin. The washout period that separated the treatment periods was 4wk. Blood samples were taken before supplementation and after 2 w of the post-resistance exercise session to determine cytochrome c and caspase-3 serum markers. Results: Resting cytochrome c and caspase-3 concentrations were not significantly different for any strawberry extract supplementation and placebo groups (P > 0.05). Cytochrome c and caspase-3 were significantly elevated after exercise in a placebo (P < 0.05) but not strawberry extract supplementation. Conclusions: Supplementation with strawberry extract attenuates intense acute exercise-induced apoptosis in healthy women.

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补充草莓提取物对非运动女性抗阻运动后Caspase -3和细胞色素c的影响

背景:运动诱导的细胞凋亡发生在多种组织中。目的:本研究旨在确定补充草莓提取物对单次抗阻运动后循环凋亡生物标志物的影响。方法:18名未经训练的健康年轻女性参加了一项随机、双盲、安慰剂对照的交叉研究。受试者参加了一次阻力运动(80% 1RM)，并服用了两周草莓提取物(每天700毫克)或麦芽糖糊精。洗脱期为4周，将两组治疗期分开。在补充前和抵抗运动后2 w后采集血样，测定细胞色素c和caspase-3血清标志物。结果:各草莓提取物组与安慰剂组的细胞色素c和caspase-3静息浓度无显著差异(P < 0.05)。运动后，安慰剂组细胞色素c和caspase-3显著升高(P < 0.05)，而草莓提取物组无显著升高。结论:补充草莓提取物可减轻健康女性剧烈急性运动诱导的细胞凋亡。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of Kermanshah University of Medical Sciences

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