Journal of Kermanshah University of Medical Sciences最新文献_第3页

The Effects of Transcranial ‎Direct Current Stimulation Over the Dorsolateral Prefrontal Cortex ‎on Cognitive Dysfunction in Alzheimer’s Disease: A Narrative Review 经颅直流电刺激前额叶背外侧皮层对阿尔茨海默病认知功能障碍的影响:叙述性综述

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-07-19 DOI: 10.5812/jkums-136442

Fatemeh Rahimi Shourmasti, Mehdi Khodamoradi, Seyedeh Masoumeh Seyedhosseini Tamijani, Raheleh Rafaiee, Carlos Augusto Carvalho de Vasconcelos, H. Mohammadi, Saba Niknamfar, H. Ghazvini

{"title":"The Effects of Transcranial ‎Direct Current Stimulation Over the Dorsolateral Prefrontal Cortex ‎on Cognitive Dysfunction in Alzheimer’s Disease: A Narrative Review","authors":"Fatemeh Rahimi Shourmasti, Mehdi Khodamoradi, Seyedeh Masoumeh Seyedhosseini Tamijani, Raheleh Rafaiee, Carlos Augusto Carvalho de Vasconcelos, H. Mohammadi, Saba Niknamfar, H. Ghazvini","doi":"10.5812/jkums-136442","DOIUrl":"https://doi.org/10.5812/jkums-136442","url":null,"abstract":"Context: Patients with mild cognitive impairment (MCI) and Alzheimer’s disease (AD) are more likely to suffer from cognitive dysfunction due to dementia. Transcranial direct current stimulation (tDCS) as a non-invasive treatment strategy has been used as an efficient strategy to improve cognitive function. Evidence Acquisition: Several studies investigating tDCS over the dorsolateral prefrontal cortex (dlPFC) were reviewed. Results: Most of these studies have targeted the left dlPFC, indicating that tDCS over the dlPFC can improve cognitive function, such as memory, visual recognition, attention, decision-making, and cognitive decline. However, there are still many unanswered questions about the effect of tDCS over the dlPFC on the connectivity of this brain region as a key node for cognitive function. Meanwhile, further research should be conducted to elucidate the effects of tDCS over the dlPFC on brain connectivity and AD biomarkers. In addition, more investigations should be conducted to identify the exact mechanisms affecting dlPFC stimulation on cognitive dysfunction in AD patients. Conclusions: Based on the results, tDCS over the DlPFC could improve cognitive function in AD patients.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75910176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Social Problem-Solving Skills Training on the Depression in Systolic Heart Failure Patients in Kermanshah 社会问题解决技能训练对收缩期心力衰竭患者抑郁的影响

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-07-15 DOI: 10.5812/jkums-136995

Sepideh Omidi, Keivan Kakabaraee, Asadollah Amiripour

{"title":"Effectiveness of Social Problem-Solving Skills Training on the Depression in Systolic Heart Failure Patients in Kermanshah","authors":"Sepideh Omidi, Keivan Kakabaraee, Asadollah Amiripour","doi":"10.5812/jkums-136995","DOIUrl":"https://doi.org/10.5812/jkums-136995","url":null,"abstract":"Background: Heart failure is common worldwide, and it is still expanding. Psychological factors such as depression are more effective on the consequences of this disease, which is necessary to seek a solution for controlling. Objectives: This study aimed to investigate the effect of social problem-solving skills training (SPSST) on depression in patients with heart failure. Methods: This semi-experimental study was conducted on two groups of ten male patients with heart failure in Kermanshah, Iran, randomly assigned to the intervention and control groups. In the intervention group, ten one-hour sessions of SPSST were done. The Beck depression inventory (BDI-13) was completed three times before, after, and three months after the intervention in both groups. The data were analyzed in SPSS v. 23 with t-test and ANCOVA to compare the groups. Results: There was a significant difference in the depression scores of the intervention group in the post-test (P = 0.000) and follow-up (P = 0.003) than before the intervention. However, there was no significant difference in the depression scores of the control group in all stages (P > 0.05). Conclusions: SPSST could improve the depression of patients with heart failure and prevent its complications, which is recommended for controlling the depression of heart failure patients.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87892179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Investigation of Clinical Significant Utility of LncRNA-LINC02389 in Patients with Esophageal Squamous Cell Carcinoma LncRNA-LINC02389在食管鳞状细胞癌中的临床应用研究

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-07-15 DOI: 10.5812/jkums-136290

Sahel Ghasemzadeh, S. Ghorbian

{"title":"Investigation of Clinical Significant Utility of LncRNA-LINC02389 in Patients with Esophageal Squamous Cell Carcinoma","authors":"Sahel Ghasemzadeh, S. Ghorbian","doi":"10.5812/jkums-136290","DOIUrl":"https://doi.org/10.5812/jkums-136290","url":null,"abstract":"Background: The lncRNA-LINC02389 gene is a long non-coding RNA, which has not been an assessed potential role in the pathogenesis of esophageal squamous cell carcinoma (ESCC). Objectives: The purpose of the present survey was to evaluate the lncRNA-LINC02389 gene expression variation in subjects with ESCC. Methods: The present survey was a preliminary investigation performed on seventy-five paired paraffin blocks including tumorous and non-tumorous marginal tissues from subjects with ESCC. After extraction of total RNA and cDNA synthesis, the lncRNA-LINC02389 gene expression change was evaluated using quantitative Real-time PCR method. Results: Our data declared that the lncRNA-LINC02389 gene was significantly down-regulated in ESCC tissues compared to the marginal tissues (P < 0.05). In addition, the findings showed a significant association between the lncRNA-LINC02389 gene expression change and tumor differentiation grade (P = 0.003). Conclusions: Our results proposed a possible carcinogenesis character of the lncRNA-LINC02389 gene and may be employed as a prognostic clinical significance in the progression of ESCC.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"123 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74684457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Essential Points Regarding Laboratory Biosafety to Prevent the Spread of SARS-CoV-2 预防SARS-CoV-2传播的实验室生物安全要点

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-07-08 DOI: 10.5812/jkums-136619

S. Mafi, Nima Fouladi Ghareshiran, Hediyeh Hamidi, Seyed Mohammad Mohyeddin Kazemeini, Poorya Davoodi, Farnaz Mozayani, B. Nowruzi, Ali Fanoodi

引用次数: 0

Surgical Repositioning Following a Severe Traumatic Intrusion of Maxillary Permanent Incisors: A Case Report 上颌恒切牙严重外伤性侵入后手术复位1例报告

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-06-13 DOI: 10.5812/jkums-135512

F. Mojarad, Shaghayegh Golshani, Parisa Vahedi

引用次数: 0

Management of Severe Pre-eruptive Caries in First Permanent Molar: A Case Report 第一恒磨牙严重出牙前龋的治疗1例

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-06-12 DOI: 10.5812/jkums-136262

Arghavan Kamali Sabeti, Shaghayegh Golshani, Fahimeh Daneshyar

引用次数: 0

Antibiotic Resistance Profile Among Stenotrophomonas Maltophilia Clinical and Environmental Isolates 嗜麦芽窄养单胞菌临床及环境分离株抗生素耐药性分析

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-05-31 DOI: 10.5812/jkums-135470

S. Emami, J. Nowroozi, R. Abiri, P. Mohajeri

{"title":"Antibiotic Resistance Profile Among Stenotrophomonas Maltophilia Clinical and Environmental Isolates","authors":"S. Emami, J. Nowroozi, R. Abiri, P. Mohajeri","doi":"10.5812/jkums-135470","DOIUrl":"https://doi.org/10.5812/jkums-135470","url":null,"abstract":"Objectives: This study was conducted to compare the resistance profile of Stenotrophomonas Maltophilia isolates -collected from clinical and environmental sources in a hospital- for different antibiotics to clarify their clonal relatedness. Methods: In this study, a total of 22 S. maltophilia isolates collected from 400 different clinical and environmental samples from Imam Reza Hospital were subjected to the analysis. Antibiotic susceptibility testing for each isolate was carried out by the disc diffusion method and according to the CLSI guidelines. Results: Among 22 S. maltophilia isolates, ten isolates were obtained from clinical specimens, and 12 were obtained from the environment. The isolates showed the lowest and highest antibiotic resistance to chloramphenicol and trimethoprim-sulfamethoxazole (18.2%) and meropenem (100%), respectively, and resistance to the other antibiotics were as follows: Chloramphenicol 18.2%, trimethoprim-sulfamethoxazole 18.2%, gentamicin 22.7%, tobramycin 50.0%, aztreonam 63.6%, amikacin 63.6, ceftriaxone 68.2%, and ceftazidime 68.2%. The antibiotic profile of S. maltophilia strains differed from tobramycin, aztreonam, amikacin, ceftriaxone, trimethoprim-sulfamethoxazole, ceftazidime, chloramphenicol, and gentamicin between clinical and environmental samples. Conclusions: Based on the high antibiotic resistance of S.maltophilia isolates and various responses to the selected antibiotic, chloramphenicol is the best therapeutic option, with 81.8% susceptibility. The early diagnosis and determination of antibiotic resistance patterns have the utmost importance.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75173754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges of COVID-19 Vaccine Booster Dose Hesitancy in Iran 伊朗对 COVID-19 疫苗加强剂量犹豫不决的挑战

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-05-31 DOI: 10.5812/jkums-137412

Sam Hajian, Mehran Rostami

引用次数: 1

Positive Troponin Level and Association with Electrocardiogram Findings Among Kurdish Patients with Acute Ischemic Stroke 库尔德急性缺血性卒中患者肌钙蛋白阳性水平与心电图表现的关系

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-04-27 DOI: 10.5812/jkums-134193

Hadi Gharebaghian Azar, Azita Mahmoudi, A. Ghasemi, H. Mohammadi

{"title":"Positive Troponin Level and Association with Electrocardiogram Findings Among Kurdish Patients with Acute Ischemic Stroke","authors":"Hadi Gharebaghian Azar, Azita Mahmoudi, A. Ghasemi, H. Mohammadi","doi":"10.5812/jkums-134193","DOIUrl":"https://doi.org/10.5812/jkums-134193","url":null,"abstract":"Background: Cardiac troponins T and I are specific myocardial injury markers associated with acute ischemic stroke. Several mechanisms have been proposed as the possible cause of myocardial damage in stroke patients. ECG abnormalities caused by acute stroke are still unknown. Objectives: The present study evaluated troponin’s level and compliance with electrocardiogram findings among Kurdish patients with acute ischemic stroke. Methods: Positive troponin was investigated among all patients diagnosed with acute ischemic stroke admitted to Imam Reza Hospital in Kermanshah from 21 March 2018 to 20 March 2019. Comprehensive electrocardiography examinations were performed and interpreted by a cardiologist and a neurologist. The presence of Q wave, T wave inversion, and ST-segment elevation or depression as evidence of coexisting cardiac ischemia were compared between patients with positive and a randomly selected group of patients with negative troponin. Results: A total of 13.2% of participants (n = 21) had atrial fibrillation (AF). One patient with positive troponin and 13.4% (n = 20) of patients with negative troponin had AF in their ECGs (P = 0.67). The frequency of other disorders, including T wave inversion, left branch bundle block, ST-segment elevation, and the presence of pathological Q wave, was 6.3% (n = 10), 5.7% (n = 9), 5% (n = 8), and 5% (n = 5), respectively. The results showed no significant relationship between positive (increase) or negative troponin with electrocardiogram abnormalities (P > 0.05). Conclusions: Since routine ECGs are obtained from all acute stroke patients, routine troponin measurements may not be necessary for all patients or may be limited to those with electrocardiographic abnormalities.","PeriodicalId":16201,"journal":{"name":"Journal of Kermanshah University of Medical Sciences","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87358469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cushing Syndrome in Pregnancy: A Case Presentation and Review of Literature 妊娠库欣综合征一例报告及文献复习

Journal of Kermanshah University of Medical Sciences Pub Date : 2023-04-21 DOI: 10.5812/jkums-129769

H. Samimagham, A. Ziaei, Mohammad Tamaddondar, Mitra Kazemi Jahromi

引用次数: 0