{"title":"Cross sectional evaluation of communication skills attitude in undergraduate medical students","authors":"Tushar R. Bagle, T. Patel, P. Baviskar","doi":"10.5455/JMAS.129418","DOIUrl":"https://doi.org/10.5455/JMAS.129418","url":null,"abstract":"","PeriodicalId":16176,"journal":{"name":"Journal of Medical and Allied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70823396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Screening for Gaucher's disease in unexplained spleenomegaly and/or thrombocytopenia: An observational study","authors":"Himangi Tak, Ashok Gupta, Himani Tak, K. Agarwal","doi":"10.5455/jmas.2070","DOIUrl":"https://doi.org/10.5455/jmas.2070","url":null,"abstract":"Gaucher's disease is a hereditary disease that can be diagnosed by determination of acid beta glucosidase enzyme activity on leucocytes but it's diagnosis is mostly delayed due to limited availability of test. The aim of the study was to determine prevalence of Gaucher's disease in patients of unexplained spleenomegaly and/or thrombocytopenia using dried blood spot filter test. This prospective cross sectional study was conducted after approval from Institutional ethical committee in 222 subjects, assuming 3.6% prevalence of the disease among unexplained cases of splenomegaly with 95% confidence interval, 0.05 α error, 80% power and with an absolute allowable error of 2.5%. After implementation of the diagnostic algorithm, samples from the patients were collected on dried blood pot filter paper and sent for analysis. Patients who tested positive by screening test were confirmed through mutational analysis done from the same sample. Data was expressed as mean, proportions and percentages. Mann Whitney test, Chi square test and Fisher's exact test were used for analysis. The prevalence of Gaucher's disease in our study population was 2.7% (CI 0.54 to 4.86) with the odds ratio for gender calculated as 3(95% CI 0.344 to 26.134). The results of this study show that the use of an appropriate diagnostic algorithm and DBS filter test facilitate early diagnosis and management of a rare disease, thereby saving a lot of medical resources while simultaneously improving the quality of life in patients.","PeriodicalId":16176,"journal":{"name":"Journal of Medical and Allied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70823673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Mujawar, V. Patil, V. Kale, Maithili S. Umate, S. Mulkutkar
{"title":"Study of relationship between interleukin-6 and markers of oxidative stress in geriatric subjects with depression","authors":"S. Mujawar, V. Patil, V. Kale, Maithili S. Umate, S. Mulkutkar","doi":"10.5455/JMAS.83045","DOIUrl":"https://doi.org/10.5455/JMAS.83045","url":null,"abstract":"","PeriodicalId":16176,"journal":{"name":"Journal of Medical and Allied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70825170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Speech language disorders unfolded in Islamabad's periphery: A tertiary health care facility experience","authors":"Nazia Mumtaz, M. Babur, G. Saqulain","doi":"10.5455/JMAS.86249","DOIUrl":"https://doi.org/10.5455/JMAS.86249","url":null,"abstract":"","PeriodicalId":16176,"journal":{"name":"Journal of Medical and Allied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70825205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nazima Begum, Syed Hassan, Purushottam Padmanabhan, S. Ahmed, A. Bardia, A. Khan
{"title":"Prevalence and comprehensive insights into molecular mechanisms in Helicobacter pylori pathogenesis","authors":"Nazima Begum, Syed Hassan, Purushottam Padmanabhan, S. Ahmed, A. Bardia, A. Khan","doi":"10.5455/jmas.49688","DOIUrl":"https://doi.org/10.5455/jmas.49688","url":null,"abstract":"It has been estimated that 4.4 billion individuals are infected with Helicobacter pylori and the prevalence of the infection varies globally ranging from the highest reported in Africa (70.1%) to lowest in Switzerland (18.9%). The prevalence is still abundant in developing countries and is due to the outcome of low socioeconomic status and poor sanitation. Helicobacter pylori infection is implicated in several pathological states and is confronting a gigantic challenge to the global health community. This review provides an extensive picture of Helicobacter pylori infection prevalence and its association with disease outcomes using myriad sample studies, emphasizing detection using gastric biopsy. Moreover novel molecular mechanisms unveiled to date are also presented to better comprehend the underlying events that triggers the epidemiological effects. Data and mechanistic pathways presented in this review aid in improved regulation of Helicobacter pylori infection and assists in designing and crafting new drugs to treat the associated clinical conditions.","PeriodicalId":16176,"journal":{"name":"Journal of Medical and Allied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70824837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantitative study demonstrating positive association between caregiver's financial knowledge and hospital's financial performance in the UAE","authors":"Mishal Tariq, S. Mohiuddin","doi":"10.5455/jmas.96174","DOIUrl":"https://doi.org/10.5455/jmas.96174","url":null,"abstract":"","PeriodicalId":16176,"journal":{"name":"Journal of Medical and Allied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42640595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Ahmed, Kallappa Herakal, K. Siddalingappa, M. Samad
{"title":"A case of ulcerative livedoid vasculopathy treated successfully with pentoxifylline and colchicine","authors":"F. Ahmed, Kallappa Herakal, K. Siddalingappa, M. Samad","doi":"10.5455/jmas.108897","DOIUrl":"https://doi.org/10.5455/jmas.108897","url":null,"abstract":"","PeriodicalId":16176,"journal":{"name":"Journal of Medical and Allied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70823011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Sharma, Dileep Kumar, Sudhir Mishra, G. Yadav, A. Gupta
{"title":"Changes in urodynamic bladder parameters in patients with spinal cord injury","authors":"C. Sharma, Dileep Kumar, Sudhir Mishra, G. Yadav, A. Gupta","doi":"10.5455/jmas.110311","DOIUrl":"https://doi.org/10.5455/jmas.110311","url":null,"abstract":"","PeriodicalId":16176,"journal":{"name":"Journal of Medical and Allied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70823076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of innate immune cells response in COVID-19","authors":"A. Khan","doi":"10.5455/jmas.110798","DOIUrl":"https://doi.org/10.5455/jmas.110798","url":null,"abstract":"Infected cells and DCs can stimulate the innate immunity by secreting interferons (IFN) which may further interact with healthy cells to improve the resistant against to the infection and also prevent the viral spread effectively DCs population along with the expression of MHCs, chemokine receptors and TRAIL on DCs are very important markers for identifying the immune responses against COVID-19 infection during the viral progression and treatment of different category of patients","PeriodicalId":16176,"journal":{"name":"Journal of Medical and Allied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70823115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combination model for sustainable change by utilizing the Kotter's change model and the Hersey and Blanchard's leadership model for improving medication errors reporting","authors":"S. Mohiuddin, K. Mohteshamuddin","doi":"10.5455/jmas.76372","DOIUrl":"https://doi.org/10.5455/jmas.76372","url":null,"abstract":"","PeriodicalId":16176,"journal":{"name":"Journal of Medical and Allied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70825003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}