Journal of long-term effects of medical implants最新文献

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To Determine Influence of Drill Shape on the Primary Stability of the Implant: An In Vitro Pilot Study. 确定钻头形状对种植体初级稳定性的影响:一项体外试验研究。
Journal of long-term effects of medical implants Pub Date : 2025-01-01 DOI: 10.1615/JLongTermEffMedImplants.2025057857
Prajna Shetty, Ramesh Chowdhary, Pooja P Shetty
{"title":"To Determine Influence of Drill Shape on the Primary Stability of the Implant: An In Vitro Pilot Study.","authors":"Prajna Shetty, Ramesh Chowdhary, Pooja P Shetty","doi":"10.1615/JLongTermEffMedImplants.2025057857","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2025057857","url":null,"abstract":"<p><strong>Introduction: </strong>This study evaluated whether drill shape and bone preparation influences the primary stability of the implant using resonance frequency analysis and insertion torque values.</p><p><strong>Materials and methodology: </strong>In this study, four most common, commercially available drill systems were used in this study. Bovine bone was chosen for the study. All the implants were chosen of the same dimension (3.5 mm ȕ 13 mm) to avoid bias and error. For convenience the study was divided into two parts. Part I of the study included performing osteotomy per manufacturer's instructions with a variability in the speed of the drilling at 300 rpm and 800 rpm, respectively. All the implants were placed at bone level, which was checked by taking radiographs. The primary stability of the implants of all the four different companies were measured using an ISQ machine (Penguin, Sweden). Part II of the study involved single drilling kit for the study. Sequential drilling protocol is selected for the second part of the study. All the four-implant system are placed using the same set of drill system. The implants are placed at 300 rpm. ISQ values are recorded using RFA machine (Penguin, Sweden) for each implant. IOPA was also recorded for the study.</p><p><strong>Results: </strong>The results were subjected to analysis.</p><p><strong>Conclusion: </strong>The results of this study suggest that implant drill shape did not have any significant effect on the overall primary stability of the implant. However, in certain implants, due to their unique design, custom drilling kits might be more feasible to use.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 3","pages":"29-35"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Analysis of Different Implant Macrogeometry for Improved Esthetics, Inverted Body Shift, and Reverse Neck Collar Implant with Conventional Tapered Implant: A 3D Finite Element Analysis Study. 不同种植体宏观结构与传统锥形种植体美学改良、倒置体移位、反向颈领种植体的比较分析:三维有限元分析研究。
Journal of long-term effects of medical implants Pub Date : 2025-01-01 DOI: 10.1615/JLongTermEffMedImplants.2025055404
Vidit Chirimar, Anshul Trivedi, Deepesh Saxena, Roma Goswami
{"title":"Comparative Analysis of Different Implant Macrogeometry for Improved Esthetics, Inverted Body Shift, and Reverse Neck Collar Implant with Conventional Tapered Implant: A 3D Finite Element Analysis Study.","authors":"Vidit Chirimar, Anshul Trivedi, Deepesh Saxena, Roma Goswami","doi":"10.1615/JLongTermEffMedImplants.2025055404","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2025055404","url":null,"abstract":"<p><p>The effect of different implant macrogeometry varying in shape along with the biomechanical effect of reduced buccal cortical bone thickness has not been studied and compared in the literature. The purpose of this finite element analysis (FEA) is to understand the stress distribution on the surrounding cortical bone for implants specially designed for use in anterior maxillary region and compare them with the conventional tapered (CT) implants. Also to assess the advantage of these implants in compromised buccal bone conditions. Two 3D FEA bone block in the maxillary anterior region were meshed with D3 type of bone. One block with uniform cortical bone thickness all around whereas other with reduced buccal cortical bone. Three different implant, inverted body shift (INB) (4.5*3.8*13), reverse neck collar (4.5*4.2*13) and CT implant (4.5*13). Each design was meshed into the different bone blocks creating total of six meshed models. An oblique load of 178 N from palatal side in the buccopalatal direction was applied. INB implant showed the best performance in terms of minimum stress concentration on the surrounding buccal bone specially in the reduced buccal cortical plate situation. The CT implant showed highest percentage increase in stress concentration on reducing buccal plate thickness. The new implant designs specially designed for maxillary anterior region where sufficient buccal bone is often lacking proved to be advantageous in such conditions due to the possibility of additional bone formation around the implant. With its high stability it should be preferred for use in compromised conditions.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 3","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Psychophysical and Neurophysiological Activities in Complete Denture Wearers and Implant Retained Overdenture Wearers: An In Vivo Study. 全口义齿佩戴者和种植固位覆盖义齿佩戴者的心理生理和神经生理活动比较:一项体内研究。
Journal of long-term effects of medical implants Pub Date : 2025-01-01 DOI: 10.1615/JLongTermEffMedImplants.2025051715
Ritu Saneja, Bappaditya Bhattacharjee, Ashish Verma, Romesh Soni, Ankita Singh, Pavan Kumar Dubey, Atul Bhatnagar
{"title":"Comparison of Psychophysical and Neurophysiological Activities in Complete Denture Wearers and Implant Retained Overdenture Wearers: An In Vivo Study.","authors":"Ritu Saneja, Bappaditya Bhattacharjee, Ashish Verma, Romesh Soni, Ankita Singh, Pavan Kumar Dubey, Atul Bhatnagar","doi":"10.1615/JLongTermEffMedImplants.2025051715","DOIUrl":"10.1615/JLongTermEffMedImplants.2025051715","url":null,"abstract":"<p><p>The present study aimed to evaluate degree of functional and physiological integration of dental implant used for implant retained overdenture and comparing these adaptive change with conventional complete denture in edentulous participants. The psychophysical method evaluated active tactile sensibility (ATS) threshold of sensory receptors of oral cavity and neurophysiological method assessed neurological changes with help of functional magnetic resonance imaging (fMRI) during mastication in participants of both the groups. Mann-Whitney U test was done to compare ATS threshold and activity of sensory cortex in fMRI before and after implant installation in completely edentulous participants. Statistical result showed significant increase (P < 0.001) in activation of sensory cortex, motor cortex, prefrontal cortex, temporal lobe in participants after wearing implant retained overdenture compared with complete denture. For 200, 100, and 80 μm articulating papers non-significant change found between two test groups. The 40 and 12 μm articulating papers showed statistically significant change in ATS threshold (P < 0.05) between two test groups in 12-14 weeks. ATS threshold decreased more in participants with Implant retained overdenture prosthesis as compared with conventional complete denture prosthesis. Most of the activation was seen in prefrontal cortex and bilateral somato-sensory cortex with implant retained prosthesis compared with conventional complete denture prosthesis.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 2","pages":"83-91"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Material and Design on the Mechanical Behavior of Implant-Supported Hybrid Fixed Prostheses. 材料与设计对种植-支撑复合固定假体力学行为的影响。
Journal of long-term effects of medical implants Pub Date : 2025-01-01 DOI: 10.1615/JLongTermEffMedImplants.2024051394
Maha Al-Ghotmi, Elie E Daou
{"title":"Impact of Material and Design on the Mechanical Behavior of Implant-Supported Hybrid Fixed Prostheses.","authors":"Maha Al-Ghotmi, Elie E Daou","doi":"10.1615/JLongTermEffMedImplants.2024051394","DOIUrl":"10.1615/JLongTermEffMedImplants.2024051394","url":null,"abstract":"<p><p>Despite the favorable long-term outcomes reported with implants-prosthetic rehabilitations, biological and technical complications may be frequent. This review aimed to describe the different implant-supported hybrid prostheses, assessing the frameworks designs, materials, mechanical behavior, and prosthetic complications. A search was done using Medline/PubMed and Scopus databases from January 1985 to December 2022. The most relevant papers were selected for the review from the retrieved papers. Manual search for list of references was also added. Mechanical complications are not unique to metal-acrylic resin HPs and have been documented with other metal-based implant-supported reconstructions and zirconia frameworks. Prosthetic complications including ceramic veneer chipping and framework failures have been reported with ceramic veneered zirconia complete arch frameworks. The design, fabrication method, material and misfit of implant-supported frameworks significantly influence the rate of prosthetic complications associated with full-arch HPs.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 2","pages":"15-23"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Torque Loss in Abutment Screw: Impacts of Type and Angle of Abutments. 基台螺杆转矩损失:基台类型和角度的影响。
Journal of long-term effects of medical implants Pub Date : 2025-01-01 DOI: 10.1615/JLongTermEffMedImplants.2025055792
Sara Tavakolizadeh, Navid Ahmadi, Maryam Rezaeimajd, Rahab Ghoveizi, Bijan Heidari, Fereshteh Shahri, Amiralireza Khaledi
{"title":"Torque Loss in Abutment Screw: Impacts of Type and Angle of Abutments.","authors":"Sara Tavakolizadeh, Navid Ahmadi, Maryam Rezaeimajd, Rahab Ghoveizi, Bijan Heidari, Fereshteh Shahri, Amiralireza Khaledi","doi":"10.1615/JLongTermEffMedImplants.2025055792","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2025055792","url":null,"abstract":"<p><p>Despite the generally high success rate of dental implant treatments, some complications may also occur. One of the most common mechanical problems is screw loosening of the abutment. This study aims to assess the impact of abutment type (original vs. non-original) and angle of abutment (angled vs. straight) on torque reduction and screw loosening under cyclic loading conditions. Thirty titanium implants were divided into three groups (n = 10): original straight abutments, non-original straight abutments, and original 15° angled abutments. Each implant, and its respective abutments, were embedded in prepared acrylic blocks and torqued to 25 N.cm. twice, with a 10-minute interval between each torque application. Reverse torque values (RTV) were evaluated before and after 500,000 cycles of cycling loading at 75 Hz with a 100 N load, using an electrical torque meter. Data analysis was conducted using SPSS software (version 21), employing descriptive statistics, ANOVA, and independent t-tests. After cyclic loading, the mean RTV was 18.41 ± 1.86 N.cm in the group of original straight abutments, 13.18 ± 1.75 N.cm in the group of non-original straight abutments, and 14.76 ± 1.04 N.cm in original 15° angled abutments. Statistically significant differences were observed in mean RTV between the two groups of original and non-original abutments as well as between angled and straight abutments (< 0.001). Original straight abutments demonstrated lower torque loss after cyclic loading compared with both non-original and 15° angled abutments. The findings suggest that using original straight abutments may have better outcomes in preventing screw loosening and ensuring proper performance in clinical settings. However, it is essential to thoughtfully evaluate alternative abutment types and angles when necessary.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 3","pages":"53-62"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Microgeometry of Dental Implants on Inflammatory Mediators. 种植体微几何结构对炎症介质的影响。
Journal of long-term effects of medical implants Pub Date : 2025-01-01 DOI: 10.1615/JLongTermEffMedImplants.2025053252
Pavithran Janagarathinam, Arvina Rajasekar
{"title":"Influence of Microgeometry of Dental Implants on Inflammatory Mediators.","authors":"Pavithran Janagarathinam, Arvina Rajasekar","doi":"10.1615/JLongTermEffMedImplants.2025053252","DOIUrl":"10.1615/JLongTermEffMedImplants.2025053252","url":null,"abstract":"<p><strong>Background: </strong>After implant installation, there is an immediate inflammatory reaction. Therefore, exploring the inflammatory mediators around different surface treated dental implants is essential for long term survival of implants. The goal of this study was to compare the levels of Tumor necrosis factor-α (TNF-α) and Interleukin-10 (IL-10) in patients with sandblasted acid-etched (SLA, SLActive) and anodized (TiUnite) dental implants.</p><p><strong>Materials and methods: </strong>In this prospective clinical study, 78 patients who had undergone implant placement for missing single posterior tooth in mandible using sandblasted acid-etched and anodized surface dental implants from September 2020 to January 2021 were enrolled according to strict inclusion and exclusion criteria and were categorized into Group 1: SLA (n = 27), Group 2: SLActive (n = 26), Group 3: TiUnite (n = 25) based on the surface modification of the implants. Utilizing an ELISA kit, the levels of TNF-α and IL-10 were measured in the peri-implant crevicular fluid (PICF) at 3 months and 1-year intervals and then subjected to statistical analysis.</p><p><strong>Results: </strong>Compared to groups 1 and 2, TNF-α was high and IL-10 level was less in implants from group 3 (p < 0.05). At baseline (p < 0.05) and the 1-year follow-up (p < 0.05), there was a statistically significant difference in TNF-α and IL-10 levels between the groups on pairwise comparison. Also, an intragroup comparison revealed that in all three groups, there was a statistically significant difference from the baseline (p < 0.05).</p><p><strong>Conclusion: </strong>Higher TNF-α and lower IL-10 levels in the peri-implant crevicular fluid was observed among patients with anodized dental implants as compared to sandblasted acid-etched dental implants.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 2","pages":"69-75"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intrusion of a Non-Splinted Tooth Surrounded by Free-Standing Dental Implants: A New Phenomenon. 游离种植体包围非夹板牙的侵入:一种新现象。
Journal of long-term effects of medical implants Pub Date : 2025-01-01 DOI: 10.1615/JLongTermEffMedImplants.2024051823
Gauri Shahi, Gayathri Krishnamoorthy
{"title":"Intrusion of a Non-Splinted Tooth Surrounded by Free-Standing Dental Implants: A New Phenomenon.","authors":"Gauri Shahi, Gayathri Krishnamoorthy","doi":"10.1615/JLongTermEffMedImplants.2024051823","DOIUrl":"10.1615/JLongTermEffMedImplants.2024051823","url":null,"abstract":"<p><strong>Purpose: </strong>The popularity of dental implants as a solution for missing teeth continues to grow, and so do the challenges associated with them. The intrusion of a natural tooth adjacent to a non-splinted dental implant is one such challenge recently observed in implant prostheses. In this comprehensive review, we delve into several potential theories that could elucidate the reasons behind tooth intrusion adjacent to a lone-standing dental implant.</p><p><strong>Materials and method: </strong>The following search terms were used for the data search: (dental implant) AND (intrusion of natural tooth). Articles written only in the English language in PubMed, Scopus, and Embase databases ranging from 1987-2023 were scrutinized and only 6 articles were included in the review.</p><p><strong>Results: </strong>Freestanding implants surrounding the intruded teeth are an uncommon occurrence that can be caused by extremely tight proximal contacts that are below the height of the contour of adjacent implants. Given the absence of a periodontal ligament in implants, their response to pressure is limited, resulting in minimal movement. However, the tooth in between them could still undergo apical intrusion. The achievement of proper proximal contact of prostheses is crucial when a natural tooth is located between implant-supported prostheses. To restore the tooth's proper contours and proximal contacts, it's suggested that the proximal contacts first be relieved. This will allow the tooth to erupt again. Clinicians need to be aware of this phenomenon and should be ready to treat it if it occurs.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 2","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lumbar Interbody Fusions: Review of Uses, Techniques, and Complications. 腰椎椎体间融合术:用途、技术和并发症综述。
Journal of long-term effects of medical implants Pub Date : 2025-01-01 DOI: 10.1615/JLongTermEffMedImplants.2025058094
Daniel T DeGenova, Nathaniel J Starcher, Tristian M Rodriquez, Caleb A Hogge, Madeline A Kilby, Marque T Kriebel, Isaac Korb, F Paul DeGenova
{"title":"Lumbar Interbody Fusions: Review of Uses, Techniques, and Complications.","authors":"Daniel T DeGenova, Nathaniel J Starcher, Tristian M Rodriquez, Caleb A Hogge, Madeline A Kilby, Marque T Kriebel, Isaac Korb, F Paul DeGenova","doi":"10.1615/JLongTermEffMedImplants.2025058094","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2025058094","url":null,"abstract":"<p><p>Lumbar interbody fusion is widely accepted as a useful tool for treating lumbar spinal pathology. Appropriately choosing the correct sized implant to decrease risk of subsidence, as well as choosing the correct approach for the vertebral level, maximizes chances of success. Interbody fusion allows for indirect decompression and can increase lumbar lordosis. There are multiple approaches to lumbar interbody fusion including: anterior, oblique, lateral, transforaminal and posterior. Patient specific and anatomic factors determine which is most appropriate.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 3","pages":"63-70"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CAD/CAM Surgical Guide for Virtual Implant Planning and Placement: A Review. 虚拟种植体计划和放置的CAD/CAM手术指南:综述。
Journal of long-term effects of medical implants Pub Date : 2025-01-01 DOI: 10.1615/JLongTermEffMedImplants.2025038533
Divyansh Sinha, R Sharmila, Subhabrata Maiti, Jessy Paulraj
{"title":"CAD/CAM Surgical Guide for Virtual Implant Planning and Placement: A Review.","authors":"Divyansh Sinha, R Sharmila, Subhabrata Maiti, Jessy Paulraj","doi":"10.1615/JLongTermEffMedImplants.2025038533","DOIUrl":"https://doi.org/10.1615/JLongTermEffMedImplants.2025038533","url":null,"abstract":"<p><p>A dental implant is a surgical fixture that is placed into the jawbone and allowed to fuse with the bone over the span of a few months. It acts as an alternative for a lacking teeth.The implant surgical guide comprises a teeth formed contour which stimulates natural teeth and prosthesis. Dental implants preserve the bone that results in loss of jaw height and appearance of aging.The prefabricated dental implant can be used to locate single implants or couple of implants in a continuous manner permitting verification of implant site, angulation and rotational positions prior to the implant placement and thereby allowing more esthetic, functional and stable prosthesis. CAD/CAM has been used for decades in restorative dentistry and have improved its software in implant dentistry. Surgical guide plays an important role in optimal positioning and angulation of implants. Surgical guides have not only reduced the chances of damage to anatomic landmarks but also increased the esthetic. Guided surgery is a complete treatment concept for diagnosis, treatment planning and placement of implants with high accuracy. The main aim of this review is to know the importance, accuracy and advantages of CAD/CAM surgical guide for virtual implant placement.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 3","pages":"11-21"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic Potential of Thymoquinone in Conjunction with Mechanical Debridement for Peri-Implantitis: A Prospective Clinical Evaluation. 百里醌联合机械清创治疗种植体周围炎的治疗潜力:一项前瞻性临床评价。
Journal of long-term effects of medical implants Pub Date : 2025-01-01 DOI: 10.1615/JLongTermEffMedImplants.2025058363
Arunraaj Thanasekaran, Arvina Rajasekar
{"title":"Therapeutic Potential of Thymoquinone in Conjunction with Mechanical Debridement for Peri-Implantitis: A Prospective Clinical Evaluation.","authors":"Arunraaj Thanasekaran, Arvina Rajasekar","doi":"10.1615/JLongTermEffMedImplants.2025058363","DOIUrl":"10.1615/JLongTermEffMedImplants.2025058363","url":null,"abstract":"<p><p>Dental implants offer a reliable solution for tooth replacement, but peri-implant diseases, especially peri-implantitis, jeopardize long-term success by causing inflammation and bone loss. Mechanical debridement is the primary treatment, though its effectiveness is limited by the complex implant surface. Adjunct therapies, particularly natural bioactive compounds, like thymoquinone from Nigella sativa, have shown promise in improving treatment outcomes due to their antimicrobial, anti-inflammatory, and regenerative properties. The aim of this study was to assess the clinical efficacy of locally applied thymoquinone gel combined with mechanical debridement in treating peri-implantitis. This prospective study included 40 participants with peri-implantitis, randomized into two groups. Group 1 received mechanical debridement alone, while Group 2 received debridement with 0.2% thymoquinone gel. Clinical parameters, including plaque index (PI), gingival index (GI), peri-implant probing depth (PPD), and clinical attachment level (CAL), were measured at baseline and after 3 months. Statistical analysis was performed using paired and independent t-tests. At the 3-month follow-up, Group 2 showed significantly better outcomes in PI (0.50 ± 0.20), GI (0.62 ± 0.11), PPD (3.02 ± 0.14 mm), and CAL (3.17 ± 0.31 mm) compared to Group 1 (p < 0.05). Thymoquinone gel as an adjunct to mechanical debridement significantly improves peri-implantitis management, offering a promising therapeutic option. Further studies with longer follow-up are needed to confirm its long-term effectiveness.</p>","PeriodicalId":16125,"journal":{"name":"Journal of long-term effects of medical implants","volume":"35 3","pages":"37-43"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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