Journal of Intensive Care最新文献

{"title":"Lacosamide dosing in patients receiving continuous renal replacement therapy.","authors":"Weerachai Chaijamorn, Sathian Phunpon, Thanompong Sathienluckana, Taniya Charoensareerat, Sutthiporn Pattharachayakul, Dhakrit Rungkitwattanakul, Nattachai Srisawat","doi":"10.1186/s40560-023-00700-4","DOIUrl":"10.1186/s40560-023-00700-4","url":null,"abstract":"<p><strong>Background: </strong>Lacosamide is one of the anticonvulsants used in critically ill patients. This study aimed to suggest appropriate lacosamide dosing regimens in critically ill patients receiving continuous renal replacement therapy (CRRT) via Monte Carlo simulations.</p><p><strong>Methods: </strong>Mathematical models were created using published demographic and pharmacokinetics in adult critically ill patients. CRRT modalities with different effluent rates were added into the models. Lacosamide regimens were evaluated on the probability of target attainment (PTA) using pharmacodynamic targets of trough concentrations and area under the curve within a range of 5-10 mg/L and 80.25-143 and 143-231 mg*h/L for the initial 72 h-therapy, respectively. Optimal regimens were defined from regimens that yielded the highest PTA. Each dosing regimen was tested in a group of different 10,000 virtual patients.</p><p><strong>Results: </strong>Our results revealed the optimal lacosamide dosing regimen of 300-450 mg/day is recommended for adult patients receiving both CRRT modalities with 20-25 effluent rates. The dose of 600 mg/day was suggested in higher effluent rate of 35 mL/kg/h. Moreover, a patient with body weight > 100 kg was less likely to attain the targets.</p><p><strong>Conclusions: </strong>Volume of distribution, total clearance, CRRT clearance and body weight were significantly contributed to lacosamide dosing. Clinical validation of the finding is strongly indicated.</p>","PeriodicalId":16123,"journal":{"name":"Journal of Intensive Care","volume":null,"pages":null},"PeriodicalIF":7.1,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10633951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72014499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of therapeutic drug monitoring-based antibiotic regimen in critically ill patients: a systematic review and meta-analysis of randomized controlled trials.","authors":"Nozomi Takahashi, Yutaka Kondo, Kenji Kubo, Moritoki Egi, Ken-Ichi Kano, Yoshiyasu Ohshima, Taka-Aki Nakada","doi":"10.1186/s40560-023-00699-8","DOIUrl":"10.1186/s40560-023-00699-8","url":null,"abstract":"<p><strong>Background: </strong>The efficacy of therapeutic drug monitoring (TDM)-based antimicrobial dosing optimization strategies on pharmacokinetics/pharmacodynamics and specific drug properties for critically ill patients is unclear. Here, we conducted a systematic review and meta-analysis of randomized controlled trials to evaluate the effectiveness of TDM-based regimen in these patients.</p><p><strong>Methods: </strong>Articles from three databases were systematically retrieved to identify relevant randomized control studies. Version two of the Cochrane tool for assessing risk of bias in randomized trials was used to assess the risk of bias in studies included in the analysis, and quality assessment of evidence was graded using the Grading of Recommendations Assessment, Development, and Evaluation approach. Primary outcome was the 28-day mortality and secondary outcome were in-hospital mortality, clinical cure, length of stay in the intensive care unit (ICU) and target attainment at day 1 and 3.</p><p><strong>Results: </strong>In total, 5 studies involving 1011 patients were included for meta-analysis of the primary outcome, of which no significant difference was observed between TDM-based regimen and control groups (risk ratio [RR] 0.94, 95% confidence interval [CI]: 0.77-1.14; I² = 0%). In-hospital mortality (RR 0.96, 95% CI: 0.76-1.20), clinical cure (RR 1.23, 95% CI: 0.91-1.67), length of stay in the ICU (mean difference 0, 95% CI: - 2.18-2.19), and target attainment at day 1 (RR 1.14, 95% CI: 0.88-1.48) and day 3 (RR 1.35, 95% CI: 0.90-2.03) were not significantly different between the two groups, and all evidence for the secondary outcomes had a low or very low level of certainty because the included studies had serious risk of bias, variation of definition for outcomes, and small sample sizes.</p><p><strong>Conclusion: </strong>TDM-based regimens had no significant efficacy for clinical or pharmacological outcomes. Further studies with other achievable targets and well-defined outcomes are required.</p><p><strong>Trial registration: </strong>Clinical trial registration; PROSPERO ( https://www.crd.york.ac.uk/prospero/ ), registry number: CRD 42022371959. Registered 24 November 2022.</p>","PeriodicalId":16123,"journal":{"name":"Journal of Intensive Care","volume":null,"pages":null},"PeriodicalIF":7.1,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71482413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Japanese Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients 2023 (J-ReCIP 2023).","authors":"Takeshi Unoki, Kei Hayashida, Yusuke Kawai, Shunsuke Taito, Morihide Ando, Yuki Iida, Fumihito Kasai, Tatsuya Kawasaki, Ryo Kozu, Yutaka Kondo, Masakazu Saitoh, Hideaki Sakuramoto, Nobuyuki Sasaki, Ryuichi Saura, Kensuke Nakamura, Akira Ouchi, Saiko Okamoto, Masatsugu Okamura, Tomoki Kuribara, Akira Kuriyama, Yujiro Matsuishi, Norimasa Yamamoto, Shodai Yoshihiro, Taisuke Yasaka, Ryo Abe, Takahito Iitsuka, Hiroyasu Inoue, Yuki Uchiyama, Satoshi Endo, Kazuki Okura, Kohei Ota, Takahisa Otsuka, Daisuke Okada, Kengo Obata, Yukiko Katayama, Naoki Kaneda, Mio Kitayama, Shunsuke Kina, Ryuichi Kusaba, Masanari Kuwabara, Naoki Sasanuma, Masahiro Takahashi, Chihiro Takayama, Naonori Tashiro, Junko Tatsuno, Takahiko Tamura, Mitsuhiro Tamoto, Asuka Tsuchiya, Yusuke Tsutsumi, Tadashi Nagato, Chihiro Narita, Tomohiro Nawa, Tadayoshi Nonoyama, Masatoshi Hanada, Kotaro Hirakawa, Akiko Makino, Hirotaka Masaki, Ryosuke Matsuki, Shinya Matsushima, Wataru Matsuda, Saori Miyagishima, Masaru Moromizato, Naoya Yanagi, Kota Yamauchi, Yuhei Yamashita, Natsuhiro Yamamoto, Keibun Liu, Yuki Wakabayashi, Shinichi Watanabe, Hiroshi Yonekura, Nobuto Nakanishi, Tetsuya Takahashi, Osamu Nishida","doi":"10.1186/s40560-023-00697-w","DOIUrl":"10.1186/s40560-023-00697-w","url":null,"abstract":"<p><p>Providing standardized, high-quality rehabilitation for critically ill patients is a crucial issue. In 2017, the Japanese Society of Intensive Care Medicine (JSICM) promulgated the \"Evidence-Based Expert Consensus for Early Rehabilitation in the Intensive Care Unit\" to advocate for the early initiation of rehabilitations in Japanese intensive care settings. Building upon this seminal work, JSICM has recently conducted a rigorous systematic review utilizing the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology. This endeavor resulted in the formulation of Clinical Practice Guidelines (CPGs), designed to elucidate best practices in early ICU rehabilitation. The primary objective of this guideline is to augment clinical understanding and thereby facilitate evidence-based decision-making, ultimately contributing to the enhancement of patient outcomes in critical care settings. No previous CPGs in the world has focused specifically on rehabilitation of critically ill patients, using the GRADE approach. Multidisciplinary collaboration is extremely important in rehabilitation. Thus, the CPGs were developed by 73 members of a Guideline Development Group consisting of a working group, a systematic review group, and an academic guideline promotion group, with the Committee for the Clinical Practice Guidelines of Early Mobilization and Rehabilitation in Intensive Care of the JSICM at its core. Many members contributed to the development of the guideline, including physicians and healthcare professionals with multiple and diverse specialties, as well as a person who had been patients in ICU. Based on discussions among the group members, eight important clinical areas of focus for this CPG were identified. Fourteen important clinical questions (CQs) were then developed for each area. The public was invited to comment twice, and the answers to the CQs were presented in the form of 10 GRADE recommendations and commentary on the four background questions. In addition, information for each CQ has been created as a visual clinical flow to ensure that the positioning of each CQ can be easily understood. We hope that the CPGs will be a useful tool in the rehabilitation of critically ill patients for multiple professions.</p>","PeriodicalId":16123,"journal":{"name":"Journal of Intensive Care","volume":null,"pages":null},"PeriodicalIF":7.1,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71482424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE EFFECTIVENESS OF BRUNO MARS SONG IN DOO-WOPS &amp; HOOLIGANS ALBUM ON STUDENTS' PRONUNCIATION MASTERY","authors":"Imas Kurnia Sari","doi":"10.31602/intensive.v6i2.12851","DOIUrl":"https://doi.org/10.31602/intensive.v6i2.12851","url":null,"abstract":"The aim of this research is to find out the effect and significant difference of bruno mars song in doo-wops &amp; hooligans album for students' pronunciation mastery at Vocational High School Kartikatama Metro. Song is a media in the form of musical works that are suitable for teaching English, especially pronunciation. This research used quasi experimental design. The subjects of this research are the tenth grade students at Vocational High School Kartikatama Metro. The result of data analysis indicates that value of t obtained (to) is lower than value of t table (-16.482<2.074). Moreover, the second data indicates t obtained (to) is lower than value of t table (-13.657<2021). The conclusion are teaching English pronunciation using bruno mars song in doo-wops &amp; hooligans album is effective to increase students' pronunciation mastery and gives a significant differences. Researchers hope that this research can help future researchers to conduct similar research, especially when using English songs to teach pronunciation. Future researchers must use the latest songs in conducting further research.","PeriodicalId":16123,"journal":{"name":"Journal of Intensive Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135930050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE EFFECTIVENESS OF WEB-BASED LEARNING ON THE STUDENTS’ MOTIVATION AND ABILITY IN WRITING NARRATIVE TEXT","authors":"Nur Rahmadani, Nurhaeni Nurhaeni","doi":"10.31602/intensive.v6i2.8617","DOIUrl":"https://doi.org/10.31602/intensive.v6i2.8617","url":null,"abstract":"In English, there are four skills which must be mastered, they are listening, speaking, reading, and writing. One of the language skills is writing that important for learners to practice their capability and their understanding, how to send ideas, and how to arrange words well. The objectives of this study were students’ motivation and ability to write narrative text who are taught through web-based learning, the writing motivation and ability of students who are not taught through web-based learning and to find out whether or not there is a significant effect of web-based learning to the students' motivation and ability to write narrative text for tenth-grade students of senior high school. The research was conducted at Muhammadiyah Boarding School in Prambanan Yogyakarta. This study used experimental research with nonrandomized-groups pre-test post-test control group design as the research design. The data were collected by using tests and questionnaires in the form of pre-test and post-test. The result of inferential analysis, showed by the result of the t-test, was found that the value of the ttable (2.001) was lower than the tobtained (3.532). Thus, H0 is rejected and H1 is accepted. It means that web-based learning had a significant effect on improving students’ writing motivation and ability.","PeriodicalId":16123,"journal":{"name":"Journal of Intensive Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135930053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IMPROVING THE STUDENTS’ VOCABULARY MASTERY BY USING WORD SQUARE MEDIA COMPARATIVE STUDY OF USING KWL AND QAR STRATEGIES ON STUDENTS’ READING COMPREHENSION","authors":"Sri - Lestari","doi":"10.31602/intensive.v6i2.12696","DOIUrl":"https://doi.org/10.31602/intensive.v6i2.12696","url":null,"abstract":"Reading is a complex activity. Through reading activities, readers have responses like rejection, acceptance, and criticism of what they have read. Therefore, appropriate strategies are needed in reading learning activities for students to facilitate reading comprehension. This study aims to determine significant differences in using KWL and QAR strategies on students' reading comprehension abilities.This study used an experimental method with a post-test-only design. The population in this study were students of class VIII SMPN 5 Banjarmasin. The sampling technique used in this study was using a saturated sampling technique for as many as 261 students. The instrument used was multiple choice questions in the form of a post-test. The data analysis technique in this study was the t-test at a significance level of 5%.The results showed that the student's reading comprehension who were taught by using the KWL strategy was 52.09 lower than those of the students taught by using the QAR strategy of 57.09 with a tcount of 2.251 and a p of 0.025 (p < 0.05 ). The difference in the post-test mean of reading comprehension skills in the KWL strategy group and the QAR strategy group was 5.00. This shows that there is a significant difference in the use of KWL and QAR strategies on the reading comprehension skills of eight grade students at SMPN 5 Banjarmasin.","PeriodicalId":16123,"journal":{"name":"Journal of Intensive Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135930052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IMPROVING THE STUDENTS’ VOCABULARY MASTERY BY USING WORD SQUARE MEDIA","authors":"Ian Harum Prasasti, Yasmika Baihaqi, Bambang Eko Siagiyanto, Fitri Palupi Kusumawati, Winda Amilia","doi":"10.31602/intensive.v6i2.12886","DOIUrl":"https://doi.org/10.31602/intensive.v6i2.12886","url":null,"abstract":"The purpose of this research is to find out whether using word square media can improve the vocabulary mastery of the eleventh grade students of SMK Negeri 3 Metro. In this study, researchers conducted classroom action research (CAR) which was carried out in three cycles. Each cycle consists of planning, acting, observing and reflecting. The subjects of this study were 32 students of eleventh grade at SMK Negeri 3 Metro. In collecting data, researchers used pre-test, post-test 1, post-test 2, post-test 3, observing, interview, and questionnaire. The results of the study show that using Word square media can improve stu-dents’ vocabulary mastery at eleventh grade of SMK Negeri 3 Metro, this can be seen in the progress of the pre-test and post-test cycle 1 to cycle 3. the average of pre-test score was 42.31% and the post-test in cycle 1 was 61.37%, the average value in post-test 2 was 75.40% and the average score in cycle 3 was 81.37%. pre-test and post-test cycle 1 to post-test cy-cle 3 there was an increase of 5.97%. it means that the results of the post test have reached indicators of success that can be achieved on the results of this post-test. Students responses in using word square media that have been done can be seen that 93.45% of students gave respones very positive in learning using word square learning media and word square media can be said to be practical and easy to use for students, this can be seen from the enthusiasm of students and their spirits at the first time in using word square media.","PeriodicalId":16123,"journal":{"name":"Journal of Intensive Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135929609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"INCORPORATING CEFR PRINCIPLES IN THE DEVELOPMENT OF A HYPERTEXT POETRY LEARNING PLATFORM FOR HIGH SCHOOL STUDENTS","authors":"Sinta Indriyani, Lala Bumela Sudimantara","doi":"10.31602/intensive.v6i2.12728","DOIUrl":"https://doi.org/10.31602/intensive.v6i2.12728","url":null,"abstract":"This study examines the decline of English education in Indonesia and the need for innovative teaching methods to improve students' English proficiency. Despite Indonesia's low ranking on the English Proficiency Index, the traditional teaching approach remains prevalent, which focuses on grammar and vocabulary. The research by Sudimantara (2021) and highlight the benefits of non-traditional approaches such as incorporating nonverbal components. Lian A.-B (2017) also creates an innovative approach called reading for emotion to help students learn English better without worrying about grammar and vocabulary. The study also shows the importance of poetry and literature in English language learning, as proven by Zeman, A., Milton, F., Smith, A., &amp; Rylance, R. (2015) that poetry precedes prose and it is a knowledge management system in the world. The study employed a research and development design to demonstrate the collaboration of using pedagogy, technology, and CEFR to create innovative learning resources that shift students' mindsets and also build the students’ engagement in learning English. This study offers valuable insights into developing innovative learning resources for English language learning in Indonesia, and further research in this area could lead to more effective teaching methods and improve the English proficiency of Indonesian students.","PeriodicalId":16123,"journal":{"name":"Journal of Intensive Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136316776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE IMPLEMENTATION OF TECHNOLOGY-BASED LEARNING EVALUATION TO INCREASE ENGLISH STUDENTS' LEARNING MOTIVATION: CASE STUDY OF E-PORTFOLIO USE","authors":"Noor Aida Aflahah, Miftah Al Farhan, Hafizhatu Nadia, Asyifa Asyifa","doi":"10.31602/intensive.v6i2.12543","DOIUrl":"https://doi.org/10.31602/intensive.v6i2.12543","url":null,"abstract":"This research aims to explore in depth the use of learning evaluation using technology, namely Google Site, which seeks to develop and increase student motivation and creativity in carrying out requested evaluations. This study is an intrinsic case study which was theoretically rooted in a unique case. The case raised in this research was the potential use of e-portfolios as an alternative option in evaluating technology-based learning. This study involved one lecturer and three students as research participants who were selected based on certain criteria or by purposive sampling technique. Lecturers were selected based on their experience in implementing e-portfolios to evaluate learning, and the students were participants in the learning. Research data were collected through semi-structured interviews with open questions, direct observation, and Focus Group Discussion (FGD). The results of this study confirmed the students gave similar opinions stating that e-portfolios could increase their extrinsic and intrinsic motivation. This research only focused on students' opinions regarding the implementation of e-portfolios in increasing their learning motivation. It is hoped that future research can further explore teachers' opinions for more comprehensive results.","PeriodicalId":16123,"journal":{"name":"Journal of Intensive Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134906733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE EFFECT OF USING AUTHENTIC MATERIALS ON READING COMPREHENSION ACROSS SECONDARY STUDENT’ COGNITIVE LEARNING STYLE","authors":"Noor Aisyah, Aulia Azmi","doi":"10.31602/intensive.v6i2.8616","DOIUrl":"https://doi.org/10.31602/intensive.v6i2.8616","url":null,"abstract":"The teaching of reading nowadays is urged to empower students to cope with 21st century literacy challenges and to develop prevailing 21st century. Further, English teachers have to implement interesting and creative materials and strategies to motivate students in learning English. Compared to non-authentic materials, authentic materials seemed more promising to fulfill the demand. The aim of this study was to investigate whether or not the use of authentic materials in the classroom in teaching reading comprehension is effective toward students’ cognitive learning styles. The effect of authentic materials was compared to the non-authentic ones. This study employed a quasi-factorial 2 x 2 design and involved 68 tenth graders SMKN 3 Banjarmasin, South Kalimantan Province. The instruments used were reading comprehension posttest and GEFT. Statistical analysis was performed using SPSS 23.0 to test hypotheses at .05 level of significance. The results showed that authentic materials improved students’ reading comprehension compared to the non-authentic ones. It conforms to the theory of authentic materials and the previous studies indicating authentic material is effective in improving students’ reading comprehension. It was further found that there was no significant difference in the reading comprehension between field independent and field dependent students. Based on the results, it can be concluded that using authentic materials is promising alternative materials to help students increase students’ reading comprehension with different cognitive learning styles.","PeriodicalId":16123,"journal":{"name":"Journal of Intensive Care","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135462454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}