Journal of Evidence‐Based Medicine最新文献

{"title":"AI-Empowered Evidence-Based Research and Clinical Decision-Making","authors":"Xufei Luo, Long Ge, Lu Zhang, Yaolong Chen, Liang Du, ADVANCED working group","doi":"10.1111/jebm.70014","DOIUrl":"https://doi.org/10.1111/jebm.70014","url":null,"abstract":"","PeriodicalId":16090,"journal":{"name":"Journal of Evidence‐Based Medicine","volume":"18 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medication Management in Patients With Polypharmacy in Primary Care: A Scoping Review of Clinical Practice Guidelines","authors":"Loes Engels,&nbsp;Marjan van den Akker,&nbsp;Petra Denig,&nbsp;Henri Stoffers,&nbsp;Heike Gerger,&nbsp;Jolijn Bohnen,&nbsp;Jesse Jansen","doi":"10.1111/jebm.70015","DOIUrl":"10.1111/jebm.70015","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Inappropriate polypharmacy increases the risk of medication-related issues. Adequate management of polypharmacy is a challenge involving different healthcare professionals, complex decision-making and ideally including patient involvement. The objective of this scoping review was to provide an overview of national recommendations for medication management of patients with polypharmacy in primary care.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A scoping review of clinical practice guidelines focusing on medication management in adults with polypharmacy, applicable to primary care was performed. Databases (G-I-N, Turning Research into Practice and PubMed), network, and a global report were screened for guidelines published after 2000 in English, Dutch, German, Spanish, French, or Russian. Raw data were extracted in duplicate using an extraction framework focusing on strategies, involvement of professionals, patient involvement, and implementation. Qualitative content analysis was used. Guideline quality was assessed using AGREE-II. The study was registered with the Open Science Framework.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Eight guidelines originating from eight countries were included. The most common recommended strategy was a medication review conducted by a general practitioner and/or a community pharmacist. Tasks and target population differed per guideline. Most guidelines recommended involving the patient in the process, mostly to elicit the patient's experiences and treatment goals. Few guidelines included advice on the implementation of recommendations. Three out of eight guidelines were of good quality (AGREE-II score &gt;70% in 5/6 domains).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Most guidelines recommended a medication review, with patient involvement, as a strategy for medication management in polypharmacy in primary care. Guidance on task division and implementation of guidelines in practice was less clear. This review illustrates room for guideline improvements.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16090,"journal":{"name":"Journal of Evidence‐Based Medicine","volume":"18 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Risk Factors and Development of a Prediction Model for Intraoperative Cerebrospinal Fluid Leakage During Transsphenoidal Pituitary Adenoma Surgery","authors":"Jie Wang,&nbsp;Zhuoyuan Li,&nbsp;Yunfeng Wang,&nbsp;Zheng Peng,&nbsp;Xiaojian Li,&nbsp;Chunlei Chen,&nbsp;Huiying Yan,&nbsp;Wei Jin,&nbsp;Fang Wang,&nbsp;Lu Chen,&nbsp;Chunhua Hang,&nbsp;Wei Li","doi":"10.1111/jebm.70013","DOIUrl":"https://doi.org/10.1111/jebm.70013","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Cerebrospinal fluid (CSF) leakage may occur during transsphenoidal resection of pituitary adenomas, with implications for patient prognosis. However, although the risk factors for intraoperative CSF leakage have been widely studied and continuously explored, there are still some unknown factors that play a role.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective study was conducted by collecting clinical data from 281 patients who underwent transsphenoidal resection of pituitary adenoma at Nanjing Drum Tower Hospital between October 2020 and October 2022.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The results showed CSF leakage occurred in 60 (21.4%) patients. In the univariate analysis, we found that tumor anteroposterior diameter (<i>p</i> = 0.024), hepatic insufficiency (<i>p</i> = 0.004), tough tumor texture (<i>p</i> &lt; 0.001), and surgical protocol as complete removal (<i>p</i> = 0.01) significantly predicted the occurrence of CSF leakage. In the univariate analysis, we found that anteroposterior diameter was associated with the occurrence of intraoperative CSF leakage compared with another diameter (<i>p</i> = 0.04), indicating that the probability of CSF leakage significantly increased at the anteroposterior diameter of pituitary adenoma ≥2 cm. We included anteroposterior tumor diameter, hepatic insufficiency, complete removal, and tumor tough texture together in a multifactorial logistic regression analysis and produced a nomogram graph based on the results. In the multifactorial logistic regression analysis, the anteroposterior tumor diameter, tumor tough texture, hepatic insufficiency, and the surgical option of complete removal predicted intraoperative CSF leakage with an AUC of 0.804.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This provides a reference for assessing the risk of CSF leakage in patients before and early in the surgical procedure and may have clinical implications for better patient treatments.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16090,"journal":{"name":"Journal of Evidence‐Based Medicine","volume":"18 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Statistical Analysis of a Large-Scale Mental Health Survey Among Adolescents in Zigong, a Less-Developed City in China","authors":"Tao Zhou,&nbsp;Qiangjian Zhang,&nbsp;Na Zhao,&nbsp;Wei Xie,&nbsp;Hao Wang","doi":"10.1111/jebm.70010","DOIUrl":"https://doi.org/10.1111/jebm.70010","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To investigate and report the psychosocial health status from a survey of adolescent populations in Zigong City, Sichuan Province, China, and analyze the overall condition of adolescent mental health in economically less-developed prefecture-level urban areas of China.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A survey on the mental health status of 95,455 adolescents in Zigong was conducted using eight scales: the Strengths and Difficulties Questionnaire for Students, the Pre-psychosis Questionnaire, the Patient Health Questionnaire, the Generalized Anxiety Disorder Scale, the Children's Revised Impact of Event Scale, the Pittsburgh Sleep Quality Index, the Internet Gaming Disorder Scale Short Form, and the Warwick-Edinburgh Mental Well-Being Scale. The survey assessed mental health across eight dimensions: emotional and behavioral problems, prodromal psychosis risk, depression, anxiety, stress reactions, sleep quality, internet addiction, and positive mental health. The statistical significance of the results was validated using the Kruskal–Wallis test, Mann–Whitney <i>U</i> test, and Chi-square test.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Overall, 76.14% of adolescents in Zigong exhibited normal psychosocial health status, indicating no immediate cause for concern. Approximately 5.58% of students were identified as being in a state of extremely high-risk psychosocial alertness, necessitating prompt intervention measures. Among all educational stages, middle-school students displayed the most severe psychosocial health issues, with approximately 8.39% classified as being in an extremely high-risk psychosocial alertness state. Furthermore, female adolescents exhibited more pronounced mental health issues compared with their male counterparts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The prominence of psychological issues among Chinese adolescents in less-developed cities underscores the urgent need for normalized and systematic intervention measures. Particular attention should be directed toward implementing targeted interventions for middle-school students and female students to address their psychosocial well-being.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16090,"journal":{"name":"Journal of Evidence‐Based Medicine","volume":"18 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment for Depression Among Adults: An Evidence and Gap Map of Systematic Reviews","authors":"Liping Guo,&nbsp;Junjie Ren,&nbsp;Zhipeng Wei,&nbsp;Xinyu Huang,&nbsp;Nina Dela Cruz,&nbsp;Leonor Rodriguez Estrada,&nbsp;Zhichun Zhang,&nbsp;Howard White,&nbsp;Kehu Yang","doi":"10.1111/jebm.70011","DOIUrl":"https://doi.org/10.1111/jebm.70011","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To identify and map systematic reviews on the effectiveness of treatment for depressive disorders among adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We retrieved systematic reviews and meta-analyses of randomized controlled trials involving adults with depressive symptoms from twelve English and four Chinese databases (June 21, 2022). Using an interactive map, we visualized the effectiveness of evidence on depression based on an intervention-outcome framework. The interventions included psychotherapy, pharmacotherapy, complementary and alternative treatments, and others. The outcomes included the remission of depressive symptoms, symptoms of depressive disorder, life and social skills, and adverse events.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We included 994 systematic reviews and meta-analyses, including 32 that were review protocols, highlighting the distribution of psychotherapy, pharmacotherapy, and complementary and alternative treatments. However, the evidence and gap map (EGM) revealed significant gaps in evidence for specific interventions, populations, outcomes, and regions. While psychotherapy, pharmacotherapy, and complementary and alternative treatments dominate the landscape, the review highlighted a lack of research on interventions for specific types of depression, such as depression in people with bipolar disorder and treatment-resistant depression. It was a similar situation for underserved populations, including young and middle-aged adults, males, sexual minority individuals, and people with disabilities. The map also suggested the need for more research on the potential risks and side effects associated with both pharmacological and nonpharmacological treatments.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The contribution of this EGM was to present the available evidence on psychotherapy, pharmacotherapy, and complementary and alternative treatments for depression in adults, making available an evidence base that could inform future policy decisions and practice. It also identified evidence gaps in interventions, outcomes, population, regions, and evidence confidence. The need for further research on tailored treatments for specific populations was highlighted.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16090,"journal":{"name":"Journal of Evidence‐Based Medicine","volume":"18 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacological Interventions for Acute Pancreatitis in Adults: An Overview of Systematic Reviews","authors":"Ling Ding,&nbsp;Linge Jian,&nbsp;Jiayue Xu,&nbsp;Qiao He,&nbsp;Yuning Wang,&nbsp;Che Sun,&nbsp;Wen Wang,&nbsp;Xin Sun","doi":"10.1111/jebm.70007","DOIUrl":"https://doi.org/10.1111/jebm.70007","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To provide a comprehensive assessment of the efficacy and safety of pharmacological interventions for AP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This was an overview of systematic reviews based on randomized controlled trials comparing pharmacological interventions with placebo or blank control in adults with AP. We searched PubMed, Embase, and the Cochrane Database of Systematic Reviews from inception to January 13, 2024, with an update on February 4, 2025. The effect value of each medication on each outcome of interest defined as a “combo” was assessed. Findings were categorized as efficacious, not efficacious, or inconclusive.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fifteen reviews (167 unique trials, 12,930 participants) reported the efficacy of 14 medications on 5 outcomes, yielding 35 distinct combos. Seven combos showed efficacy with low certainty evidence: low molecular weight heparin (risk ratio 0.31, 95% confidence interval, 0.18–0.51), omega-3 fatty acids (0.30, 0.14–0.65), and antioxidants (0.69, 0.49–0.98) for mortality; low molecular weight heparin (0.38, 0.22–0.65), chengqi-series decoctions (0.48, 0.36–0.63), and ulinastatin (0.43, 0.24–0.78) for multiple organ failure; and neostigmine (mean difference –2.81, 95 % confidence interval –3.75 to –1.87) for length of intensive care unit stay. Half of the remaining combos showed no efficacy, while the other half was inconclusive for very low certainty evidence. Safety data were limited, with one review reporting no significant adverse events for neostigmine.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Some pharmacological interventions exhibited potential efficacy for specific AP outcomes, albeit with low certainty evidence. Further verifying those medications is crucial in advancing the treatment landscape for AP.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16090,"journal":{"name":"Journal of Evidence‐Based Medicine","volume":"18 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143535828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Towards Diagnostic Intelligent Systems in Leukemia Detection and Classification: A Systematic Review and Meta-analysis","authors":"Mehrad Aria,&nbsp;Zohreh Javanmard,&nbsp;Donia Pishdad,&nbsp;Vahid Jannesari,&nbsp;Maryam Keshvari,&nbsp;Mahshid Arastonejad,&nbsp;Reza Safdari,&nbsp;Mohammad Esmaeil Akbari","doi":"10.1111/jebm.70005","DOIUrl":"https://doi.org/10.1111/jebm.70005","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Leukemia is a type of blood cancer that begins in the bone marrow and results in high numbers of abnormal white blood cells. Automated detection and classification of leukemia and its subtypes using artificial intelligence (AI) and machine learning (ML) algorithms plays a significant role in the early diagnosis and treatment of this fatal disease. This study aimed to review and synthesize research findings on AI-based approaches in leukemia detection and classification from peripheral blood smear images.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic literature search was conducted across four e-databases (Web of Science, PubMed, Scopus, and IEEE Xplore) from January 2015 to March 2023 by searching the keywords “Leukemia,” “Machine Learning,” and “Blood Smear Image,” as well as their synonyms. All original journal articles and conference papers that used ML algorithms in detecting and classifying leukemia were included. The study quality was assessed using the Qiao Quality Assessment tool.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>From 1325 articles identified through a systematic search, 190 studies were eligible for this review. The mean validation accuracy (ACC) of the ML methods applied in the reviewed studies was 95.38%. Among different ML methods, modern techniques were mostly considered to detect and classify leukemia (60.53% of studies). Supervised learning was the dominant ML paradigm (79% of studies). Studies utilized common ML methodologies for leukemia detection and classification, including preprocessing, feature extraction, feature selection, and classification. Deep learning (DL) techniques, especially convolutional neural networks, were the most widely used modern algorithms in the mentioned methodologies. Most studies relied on internal validation (87%). Moreover, K-fold cross-validation and train/test split were the commonly employed validation strategies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>AI-based algorithms are widely used in detecting and classifying leukemia with remarkable performance. Future studies should prioritize rigorous external validation to evaluate generalizability.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16090,"journal":{"name":"Journal of Evidence‐Based Medicine","volume":"18 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143497058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inadequate Reporting of Harm From Randomized Clinical Trials in Top Medical Publications","authors":"Rui Zheng,&nbsp;Liyuan Tao,&nbsp;Yang Sun,&nbsp;Hongcai Shang,&nbsp;Mitchell Levine","doi":"10.1111/jebm.70006","DOIUrl":"https://doi.org/10.1111/jebm.70006","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To assess the quality of harm reporting in randomized controlled trials (RCTs) published in high-impact general medical journals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design and Setting</h3>\u0000 \u0000 <p>Publications of RCTs involving drugs compared with placebo controls, that were published in five general medical journals with high Impact Factors were identified from January 2022 to December 2023. Data relating to the presentation and discussion of harm were extracted and analyzed based on the Consort Harm framework.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We identified 175 eligible RCTs (<i>AIM</i>: <i>n</i> = 5; <i>BMJ</i>: <i>n</i> = 8; <i>JAMA</i>: <i>n</i> = 26, <i>Lancet</i>: <i>n</i> = 64, and <i>NEJM</i>: <i>n</i> = 72). None of the studies referenced the CONSORT Harms 2004 statement. Seventy-one percent of studies (<i>n</i> = 125) did not mention how harm data about patients’ symptoms were collected and 86.3% of the analyses (<i>n</i> = 151) were limited to descriptive statistics. Only 45.1% of studies (<i>n</i> = 79) discussed the balance of benefits and harms. Common limitations included unclear methodological details, selective reporting, and inadequate analysis of results.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>RCTs published in five highly cited general medical journals contain deficiencies in harm reporting. The recently updated Consort Harm 2022 provides an implementable evaluation and guidance tool and should be actively promoted among researchers, reviewers, and journal editors. More attention to adequate and reasonable reporting requirements for harms in RCTs is necessary to provide a better opportunity for evidence-based decision making.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16090,"journal":{"name":"Journal of Evidence‐Based Medicine","volume":"18 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jebm.70006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143513774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dysphagia Rehabilitation Using Digital Technology: A Scoping Review","authors":"Na-Kyoung Hwang,&nbsp;Tae-Hyung Yoon,&nbsp;Moon-Young Chang,&nbsp;Ji-Su Park","doi":"10.1111/jebm.70009","DOIUrl":"https://doi.org/10.1111/jebm.70009","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Digital health technology in swallowing rehabilitation offers personalized exercises, remote monitoring, and real-time feedback, enhancing accessibility and effectiveness of therapy. This scoping review was conducted to summarize what types and features of digital technology-based dysphagia rehabilitation interventions exist, how they are applied in patients with dysphagia, and what the effectiveness and facilitators and barriers to intervention application are.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We searched Medline Complete, Embase, CINAHL, Scopus, and gray literature for articles published between January 2000 and June 2023. We used subheadings and terms related to digital health, dysphagia, and rehabilitation to search for articles. The included studies were mapped according to the types and features, effectiveness, enablers, barriers, and future improvements of swallowing rehabilitation using digital technologies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-five studies met the inclusion criteria. Three types of digital swallowing rehabilitation interventions were identified: home-based rehabilitation using the mHealth app, synchronous telepractice and monitoring, as well as game-based biofeedback and tracking. The included studies reported positive results regarding physiological changes in swallowing function, swallowing performance, and quality of life. Digital unfamiliarity, resources for digital access, and technical issues related to the failure of the mobile device operating system were identified as barriers to the use of digital swallowing rehabilitation technology and future improvements.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Digital technology has potential value in dysphagia rehabilitation. In the future, developing various interventions utilizing the advantages of digital technology and conducting additional research to validate their effectiveness is necessary. Additionally, improved digital familiarity, better accessibility, better technology, and management practices will be needed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16090,"journal":{"name":"Journal of Evidence‐Based Medicine","volume":"18 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143497183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can GPTs Accelerate the Development of Intelligent Diagnosis and Treatment in Traditional Chinese Medicine? A Survey and Empirical Analysis","authors":"Yan Guo,&nbsp;Heyuan Wang,&nbsp;Xue Ren,&nbsp;Tengjiao Wang,&nbsp;Wei Chen,&nbsp;Ziming Xu,&nbsp;Hui Ge","doi":"10.1111/jebm.70004","DOIUrl":"https://doi.org/10.1111/jebm.70004","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <p>Intelligent traditional Chinese medicine (TCM) is a key pathway toward the modernization and globalization of TCM in the era of artificial intelligence. Due to its unique terminology and diagnostic framework, TCM's intelligentization process has long faced a range of challenges, from the digitization and formalization of knowledge bases to the differentiation of syndromes and personalized treatment. Recently, the advent of large language models (LLMs) like GPTs has marked a transformative milestone in semantic understanding tasks, attracting widespread attention from the medical, academic, and industrial communities. Nonetheless, LLMs often suffer from accuracy and logical reasoning limitations within specific fields and may manifest hallucinations in the generative outputs. Through a comprehensive review of existing literature and empirical analyses, this study delves into the potential and challenges of adapting LLMs to TCM. Promising perspectives on future developments at this innovative intersection are discussed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16090,"journal":{"name":"Journal of Evidence‐Based Medicine","volume":"18 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143475546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}