Journal of Indian Association of Pediatric Surgeons最新文献

{"title":"Germ Cell Neoplasia <i>In situ</i> in Undescended Testis: A Myth or Reality?","authors":"Pravash Ranjan Mishra, Suvendu Purkait, Aditya Arvind Manekar, Bikasha Bihary Tripathy","doi":"10.4103/jiaps.jiaps_182_24","DOIUrl":"10.4103/jiaps.jiaps_182_24","url":null,"abstract":"<p><strong>Background: </strong>Untreated cryptorchid testes are in risk of intratubular germ cell neoplasia and subsequently may give rise to invasive germ cell tumors.</p><p><strong>Materials and methods: </strong>Tissue samples were obtained from patients undergoing orchidectomy or orchiopexy and were subjected to routine histopathological and immunohistochemical examinations.</p><p><strong>Results: </strong>Forty-three patients were enrolled in this study out of which 30 samples were collected. The mean age of patients was 9.16 years. One case (6.7%) showed positivity of the germ cell neoplasia with anto placental alkaline phosphatase and Anto CD-117 positive. Other histopathological findings such as fibrocollagenous tissue and Leydig cell hyperplasia were reported.</p><p><strong>Conclusion: </strong>Early surgical management is of importance for a better outcome in cases of undescended testes.</p>","PeriodicalId":16069,"journal":{"name":"Journal of Indian Association of Pediatric Surgeons","volume":"30 1","pages":"66-69"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postsurgical Guillain-Barré Syndrome Presenting as Seizures: A Rare Case Report.","authors":"Santosh Kurbet, Akshata Angadi, Mihir Kaustubh Aurangabadkar, Mahesh Kamate","doi":"10.4103/jiaps.jiaps_175_24","DOIUrl":"10.4103/jiaps.jiaps_175_24","url":null,"abstract":"<p><p>Postsurgical Guillain-Barré syndrome (GBS) is an unrecognized and uncommon complication seen in children. Postsurgical GBS complicated by severe acute hypertension secondary to dysautonomia can present as seizures because of underlying posterior reversible encephalopathy syndrome. The neuropathic symptoms of GBS following surgery are often missed and attributed to other postoperative problems like sedation and postoperative pain. Here, we report a challenging case of seizures in the postoperative period that was due to autonomic dysfunction secondary to GBS following bowel surgery.</p>","PeriodicalId":16069,"journal":{"name":"Journal of Indian Association of Pediatric Surgeons","volume":"30 1","pages":"110-112"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydatid Cyst Liver Masquerading as a Gastric Duplication Cyst: A Diagnostic Dilemma.","authors":"Shorya Katiyar, Rajat Piplani, Sarita Syal, Bijay Kumar Suman, Prashant Kothari, Rohan Saini","doi":"10.4103/jiaps.jiaps_201_24","DOIUrl":"10.4103/jiaps.jiaps_201_24","url":null,"abstract":"","PeriodicalId":16069,"journal":{"name":"Journal of Indian Association of Pediatric Surgeons","volume":"30 1","pages":"116"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interstitial Cells of Cajal and Ganglion Cell Distribution in Sigmoid Stomal Limbs and Distal Rectum after Stoma Formation in Male Anorectal Malformation Patients Undergoing Staged Repair.","authors":"Priyanka Bamoria, Simmi K Ratan, Shasanka Shekhar Panda, Sujoy Neogi, Shramana Mandal, Chiranjiv Kumar, Gaurav Saxena","doi":"10.4103/jiaps.jiaps_155_24","DOIUrl":"10.4103/jiaps.jiaps_155_24","url":null,"abstract":"<p><strong>Introduction: </strong>This study was undertaken to assess the distribution of ganglion cells (GCs) and interstitial cells of Cajal (ICCs) across different points of distal rectal pouch in anorectal malformation (ARM) patients over the three stages of repair. We hypothesize that along with the surgical factors, there could be intrinsic factors as well which can be the cause of dysmotility in these patients after surgical repair.</p><p><strong>Methodology: </strong>Full-thickness colonic biopsy specimens were taken from the proximal stoma, distal stoma, and distal rectal pouch of 21 boys aged 0-8 months undergoing 3 staged repair of ARM at our tertiary care center between August 2022 and December 2023. There was an interstage interval of approximately 12-14 weeks. All underwent high-divided sigmoid colostomy in stage 1. Biopsy specimens for GC and ICC number were routinely processed, and immunohistochemistry was done for CD117. The data was assessed and compared with respect to location and stage of surgery.</p><p><strong>Results: </strong>Both GC and ICC showed a gradual decrease in mean number over three stages for both proximal and distal ends of colostomy. For proximal stoma, the distribution of either cell type did not differ across the stages, but for distal stoma, the number of cells was significantly lower in the second stage (following colostomy, before posterior sagittal anorectoplasty). However, no difference was noted between the second and third stages. This indicates that factors during/just after colostomy itself must be responsible for decrease in ICC/GC.</p><p><strong>Conclusion: </strong>Lesser number of GC and/or ICC in the distal pouch from stage 2 onward may point toward its association with projected hypomotility in ARM patients. Apart from innate distribution, we also infer that this could be consequent to vascular insult which may occur at the time of divided colostomy. Loop stoma may be a better alternative as vascularity is uninterrupted in loop colostomy.</p>","PeriodicalId":16069,"journal":{"name":"Journal of Indian Association of Pediatric Surgeons","volume":"30 1","pages":"22-27"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent Tracheal Schwannomas: A Case Report and Literature Review.","authors":"Rakhesh Mallesh, M M Zameer, Vinay Chandrashekar, Sanjay Rao","doi":"10.4103/jiaps.jiaps_173_24","DOIUrl":"10.4103/jiaps.jiaps_173_24","url":null,"abstract":"<p><p>Tracheal schwannomas are rare benign tumors in pediatric age group. We report a case of recurrent distal tracheal tumor in a 12 year old boy successfully managed with resection under cardiopulmonary bypass and review the relevant literature.</p>","PeriodicalId":16069,"journal":{"name":"Journal of Indian Association of Pediatric Surgeons","volume":"30 1","pages":"113-115"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mission 2034: Making Pediatric Surgery Greater - Presidential Address Delivered at the Golden Jubilee Conference of Indian Association of Pediatric Surgeons, Rishikesh, 2024.","authors":"S Ramesh Babu","doi":"10.4103/jiaps.jiaps_253_24","DOIUrl":"10.4103/jiaps.jiaps_253_24","url":null,"abstract":"","PeriodicalId":16069,"journal":{"name":"Journal of Indian Association of Pediatric Surgeons","volume":"30 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case of Antenatally Ruptured Rectal Duplication Cyst in a Newborn with Spina Bifida and Ectopic Kidney: Diagnostic and Surgical Challenges.","authors":"Posam Manoj Kumar, Mandakini T Kotaiah, Gudla Keerthi","doi":"10.4103/jiaps.jiaps_183_24","DOIUrl":"10.4103/jiaps.jiaps_183_24","url":null,"abstract":"<p><p>Rectal duplication cysts are a rare entity, representing only 5% of alimentary tract duplications, with posterior rectal duplications being the most common. However, clinical presentations can vary significantly. We present a unique case of a 5-day-old female with an antenatally ruptured rectal duplication cyst associated with spina bifida and an ectopic kidney. The infant presented with a fleshy mass over the left gluteal region, and imaging revealed an ectopic left kidney and spina bifida. The preoperative diagnosis was complicated by the antenatal rupture of the cyst, which was confirmed intraoperatively and through biopsy. Surgical excision of the lesion was performed, and the postoperative recovery was uneventful. This case underscores the diagnostic challenges associated with ruptured rectal duplication cysts in the newborn period, highlighting that complete surgical excision is the preferred treatment to prevent further complications.</p>","PeriodicalId":16069,"journal":{"name":"Journal of Indian Association of Pediatric Surgeons","volume":"30 1","pages":"101-103"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exstrophied Variant of Rectal Duplication Cyst with Supernumerary Kidney.","authors":"Shreyas Dudhani, Amit Kumar Sinha, Rashi Rashi, Keerthana Bachala, Amber Parwaiz","doi":"10.4103/jiaps.jiaps_169_24","DOIUrl":"10.4103/jiaps.jiaps_169_24","url":null,"abstract":"<p><p>Neonate with a perineal mass may rarely present with a rectal duplication cyst. The index case presented with a perineal located mass which on evaluation revealed an exstrophied variant of a duplication cyst neonate associated with supernumerary kidney. She was subsequently managed surgically with the resection of mass and a diversion colostomy. It is understood that these extrophic variants are neither cystic nor tubular and maybe attached to the rectum or vagina but do not communicate with it. Previous reports of such rectal cysts are less than ten in number with this being the only one reported with supernumerary kidney.</p>","PeriodicalId":16069,"journal":{"name":"Journal of Indian Association of Pediatric Surgeons","volume":"30 1","pages":"107-109"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Correlation of Basic Fibroblast Growth Factor and Vascular Endothelial Growth Factor with Radiological Tumor Size in Pediatric Nephroblastoma and Neuroblastoma: A Prospective Study.","authors":"Pujana Kanneganti, Basant Kumar, Priya Mathew, Vikas Agarwal, Rajanikant Yadav, Ankur Mandelia, Vijai Datta Upadhyay","doi":"10.4103/jiaps.jiaps_153_24","DOIUrl":"10.4103/jiaps.jiaps_153_24","url":null,"abstract":"<p><strong>Introduction: </strong>Angiogenesis plays an important role in the growth, progression, and metastasis of solid tumors. Basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF); both are potent angiogenic factors implicated with the growth and metastasis of solid tumors mostly in adult studies. Rapidly growing and large-size tumors have a positive correlation with these factors which are measured in serum and urine samples of patients. There is little literature available for pediatric patients that compare the computed tomography findings (size) of pediatric solid tumors with serum VEGF and serum/urinary bFGF.This prospective study aims to determine the correlation of serum VEGF and serum/urinary bFGF with the size of common pediatric solid tumors (nephroblastoma and neuroblastoma [NB]) to determine its diagnostic and prognostic significance.</p><p><strong>Materials and methods: </strong>A prospective case-control study was done for 3 years (December 2020 to November 2023) at our institute. All children aged 1 day to 18 years admitted with the diagnosis of NB and nephroblastoma (Wilms' tumor [WT]) were included after parental consent. The control group includes children of varying ages without any malignancy. Blood and urinary samples were collected at admission before or a week after the biopsy and the level of bFGF and VEGF was analyzed with the ELISA method. Triple-phase computed tomographies along with recommended evaluation were performed according to the tumor as per international standard protocols. Appropriate statistical analyses were done.</p><p><strong>Results: </strong>A total of 30 patients were included in the cohort, of which 13 patients were with the diagnosis of WT. Only 7 patients had metastatic disease. All the patients were treated with neoadjuvant chemotherapy, surgery, and radiotherapy according to their presentation and tumor stage. Both the growth factors, i.e., VEGF (median value - 314.38 pg/mL) and bFGF (median value - 18.96 pg/mL), are elevated in all the tumor patients in comparison with the controls (median VEGF - 100.51 pg/mL and bFGF - 15.6 pg/mL). When compared with the tumor size, no significant associations are found (with VEGF <i>P</i> - 0.40 and with bFGF <i>P</i> - 0.44).</p><p><strong>Conclusion: </strong>Although no satistically significant correlations were found between serum/urinary levels of bFGF and VEGF with tumor size, this study showed the raised median serum value of bFGF and VEGF in patients with NB and WT in comparison to controls and provided the rationale to explore this issue on a larger group of patients.</p>","PeriodicalId":16069,"journal":{"name":"Journal of Indian Association of Pediatric Surgeons","volume":"30 1","pages":"36-40"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Study of Urethral Plate and Glans Characteristics in Experimentally Created Hypospadias and Clinical Cases Undergoing Snodgrass Repair.","authors":"Manish Rajput, Archika Gupta, Gurmeet Singh, Rahul Kumar Rai, Shiv Narain Kureel, Punita Manik, Navneet Chauhan, Jiledar Rawat","doi":"10.4103/jiaps.jiaps_116_24","DOIUrl":"10.4103/jiaps.jiaps_116_24","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to study the urethral plate and glans configuration in experimentally created hypospadias in male human cadavers and its comparison with hypospadias patients planned for tubularized incised plate (TIP) urethroplasty.</p><p><strong>Materials and methods: </strong>In five fresh human cadavers, hypospadias was created by placing one blade of scissors in the urethra and the other onto the ventral median raphe and cutting through the skin, penile dartos, and urethra and laying open urethral edges were sutured to edges of penile skin to create hypospadias. Urethral plate characteristics were recorded using Likert scale and the glans groove using the Plate Objective Scoring Tool (POST). The characters were compared with fifty hypospadias planned for TIP.</p><p><strong>Results: </strong>In experimentally created hypospadias, all urethral plates were very favorable with POST ratio being >1.5. In 50 hypospadias, cleft urethral plate with POST ratio >1.2 was recorded in 5 (10%). Flat urethral plate was recorded in 20 with 12 showing POST ratio >1.2 and 8 had <1.2. Narrow urethral plate was recorded in 25 with 15 showing POST ratio of >1.2 while 10 had <1.2. In all patients of POST ratio <1.2, ventral migration of dorsal end of glans meatus was present.</p><p><strong>Conclusions: </strong>Only 10% of hypospadias match the configuration of experimentally created hypospadias and are suitable for classic TIP. Patients with narrow urethral plates are suitable for TIP with the inclusion of paraurethral plate penile skin strip. All categories with POST score <1.2 are suitable for TIP with inner prepucial graft in incised glans bed and incised urethral plate.</p>","PeriodicalId":16069,"journal":{"name":"Journal of Indian Association of Pediatric Surgeons","volume":"30 1","pages":"8-13"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}