I. Romaniouk, I. Ortí, A. Martínez, M. Mravcová, B. Sánchez, M. Aparicio, R. Borrás, J. Ribes, Y. Aznar, Y. Blanco, E. Bea, J. Graña, B. González, M. Candel
{"title":"Management of acute renal failure secondary to a renal infarction and renal thrombosis in a monorenal 76-year-old patient","authors":"I. Romaniouk, I. Ortí, A. Martínez, M. Mravcová, B. Sánchez, M. Aparicio, R. Borrás, J. Ribes, Y. Aznar, Y. Blanco, E. Bea, J. Graña, B. González, M. Candel","doi":"10.15761/nrd.1000170","DOIUrl":"https://doi.org/10.15761/nrd.1000170","url":null,"abstract":"Kidney infarction is a rare pathology with a low incidence registered, however it is most likely that the real incidence is quite higher because many cases are not diagnosed. The clinical presentation varies from nausea to a complete kidney failure when involves most of the parenchyma, therefore affecting the proper kidney function. As for the treatment several option might be considered. The in-situ artery thrombosis is one of the best options followed by anticoagulation or endovascular therapy. There are no standard options for a monorenal patient facing the pathology described, especially with an unsuspected final diagnose is involved.","PeriodicalId":160607,"journal":{"name":"Nephrology and Renal Diseases","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116656241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"β2M shuttle hypothesis in the dialysis related amyloidosis (DRA)","authors":"Y. Motomiya, Y. Uji, Y. Ando","doi":"10.15761/nrd.1000157","DOIUrl":"https://doi.org/10.15761/nrd.1000157","url":null,"abstract":"As well approved in current experimental studies over 20years or more, the intermediate molecules, i.e., the conformational variants of globular native protein, had been confirmed in the transitional process of the in vitro amyloidogenesis [1]. The presence of this molecule in hemodialysis (HD) setting had firstly reported in amyloid tissue from a femoral bone cyst in patient with the DRA by Bellotti’s group [2]. Then, we had identified this intermediate β2microglobulin (I-β2M) using with capillary electrophoresis (C.E) in serum not only from HD patients but also the chronic kidney disease (CKD) patients and healthy persons, then, we proposed “β2M shuttle hypothesis “ as amyloidogenic concept in clinical setting of HD [3,4]. This concept is based upon 5 evidences as follows:","PeriodicalId":160607,"journal":{"name":"Nephrology and Renal Diseases","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123531666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Mohammed, A. Ramrattan, P. Poon-king, A. Bissessar, A. Ramesar, S. Giddings, Av Rao
{"title":"Anti-glomerular basement membrane disease case series in Trinidad and Tobago","authors":"E. Mohammed, A. Ramrattan, P. Poon-king, A. Bissessar, A. Ramesar, S. Giddings, Av Rao","doi":"10.15761/nrd.1000179","DOIUrl":"https://doi.org/10.15761/nrd.1000179","url":null,"abstract":"","PeriodicalId":160607,"journal":{"name":"Nephrology and Renal Diseases","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114421470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. C. Santacruz, A. Santacruz, Ana K Vásquez, P. Reinoso, C. Sulbarán, María G Santacruz
{"title":"Experience of COVID 19 disease on 159 Ecuadorian chronic dialysis patients","authors":"J. C. Santacruz, A. Santacruz, Ana K Vásquez, P. Reinoso, C. Sulbarán, María G Santacruz","doi":"10.15761/nrd.1000174","DOIUrl":"https://doi.org/10.15761/nrd.1000174","url":null,"abstract":"Aim: In December 2019, first Covid-19 disease cases were reported. The pandemic spread with 42,039,763 cases and 1,141,223 deaths worldwide with 156,451 confirmed cases and 12,500 deaths in Ecuador. The aim of this work is to share characteristics and clinical outcomes of 159 dialysis patients in Quito during pandemic. Materials and methods: Observational-prospective-unicenter study. Fifty-six consecutive patients (35%) presented COVID19 symptoms and followed since April to 30 September 2020. Positive nasopharyngeal PCR testing confirmed diagnosis. Low oxygen saturation (LOS) classified disease as severe, moderate if symptoms without LOS and asymptomatic if no symptoms. Hospital-stay, time disease, mortality, contagious rate data were collected. Results: Thirty-seven patients (23.3%) tested positive. Patients with LOS at presentation and hospitalized were older when compared with those without LOS (61.6 ± 11.9 vs 48.9 ± 11.9 years; p=0.02) and non-hospitalized (60.3 ± 12.7 vs 51.4 ± 15.6 years; p=0.02). Ten died (27%), mortality was significative in patients with previous pulmonary disease (p=0.01), LOS (p=0.03), hospitalization (p=0.01), and severe disease (p=0.03). Median hospital stay was 7 days (3-13), time disease was 17 days (6-25) and 10 days (6-22) until death. Conclusion: COVID-19 disease has increased mortality and health care demand in dialysis patients. Mortality was inferior to other series, and significative when previous pulmonary pathology, low oxygen saturation, hospitalization and severe disease were present. *Correspondence to: Juan C Santacruz, Nephrology and dialysis unit, Menydial Kidneys Clinic, Quito-Ecuador, Tel: 593979037586; E-mail: geovas40@hotmail.com","PeriodicalId":160607,"journal":{"name":"Nephrology and Renal Diseases","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117097461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martin Scoglio, B. Vogt, A. Foglia, Claudia Paola Ferrier-Guerra
{"title":"Lithium nephrotoxicity: when and why? Experience of nephrology and psychiatry outpatient clinics","authors":"Martin Scoglio, B. Vogt, A. Foglia, Claudia Paola Ferrier-Guerra","doi":"10.15761/nrd.1000192","DOIUrl":"https://doi.org/10.15761/nrd.1000192","url":null,"abstract":"","PeriodicalId":160607,"journal":{"name":"Nephrology and Renal Diseases","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116389089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Natural health wellness: an effective prevention of DKD","authors":"N. Futrakul, P. Futrakul","doi":"10.15761/nrd.1000156","DOIUrl":"https://doi.org/10.15761/nrd.1000156","url":null,"abstract":"Renal microvascular disease and diabetic kidney disease develop at the early course of diabetes mellitus. Under common practice, vasodilator treatment at DKD stage 3 or later fails to correct renal ischemia, due to the altered vascular homeostasis associated with an impaired angiogenesis. In addition, there is also elevated antiangiogenic factors in the blood that induce a progressive renal microvascular disease. Under current vision, therapeutic strategy should be implemented at the early DKD stages (1 and 2). Vasodilator treatment at this early stage would enhance the renal perfusion, and restore the renal, function. Such treatment in conjunction with the patient’s self-sufficiency philosophy under natural health wellness regime, would minimize the development of end-stage renal disease in diabetes mellitus. *Correspondence to: Narisa Futrakul MD, Ph.D, Department of Physiology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Bangkok,10400, Thailand, Tel: +66 2 256 4951; Fax: +66 2 256 4911; E-mail: fmednft@yahoo.com","PeriodicalId":160607,"journal":{"name":"Nephrology and Renal Diseases","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133887236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Vlasić-Matas, H. Raos, M. Vučković, Stjepan Radić, V. Čapkun
{"title":"Prevalence of Ureaplasma urealyticum, Mycoplasma hominis and Chlamydia trachomatis in patients with uncomplicated recurrent urinary tract infections","authors":"J. Vlasić-Matas, H. Raos, M. Vučković, Stjepan Radić, V. Čapkun","doi":"10.15761/nrd.1000150","DOIUrl":"https://doi.org/10.15761/nrd.1000150","url":null,"abstract":"Aim: To assess the prevalence of Ureaplasma urealyticum, Mycoplasma hominis and Chlamydia trachomatis in patients with chronic urinary tract infections (UTIs) and its correlation with leukocyturia and symptoms. Methods: The study included 220 patients (130 women and 90 men) presenting with chronic voiding symptoms and sterile leukocyturia. Urine, urethral swabs and cervical swabs (for women patients) were taken to determine the presence of these pathogens. Patients were treated by tetracycline and followed up three and six months after initial therapy. Results: In 186 (85%) out of 220 patients, U. urealyticum was found, while C. trachomatis was present in 34 patients (15%). In majority of female patients (112 out of 130; 86%) U. urealyticum was found. In addition to ureaplasma, in eight patients M. hominis was found. C. trachomatis was identified in 18 female patients (14%). In 74 out of 90 (82%) male patients U. urealyticum was detected while in six of them M. hominis was also found. C. trachomatis was identified in 16 male patients (18%). U. urealyticum was significantly related to leukocyturia, as opposed to C. trachomatis (p<0,001). Women had more frequent symptomatology (p = 0,015) and higer leukocyturia (p<0.001). Conclusion: Leukocyturia is more common find in U. Urealyticum infection than in patients with C. trachomatis infection. It is therefore advisable to test patients with uncomplicated reccurent UTIs for the presence of these atypical pathogens. Symptomatic patients, as well as their partners, should be treated accordingly. *Correspondence to: Jadranka Vlasic-Matas, Polyclinic Nephrology Department, Split, Croatia, Tel: 0038521317320; Fax: 0038521317322; E-mail: jadranka.vlasic-matas@st.t-com.hr","PeriodicalId":160607,"journal":{"name":"Nephrology and Renal Diseases","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132318926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute kidney injury (AKI): Risk assessment and management in hospital versus community","authors":"Kugananda Sri Paranthaman, M. Jawad","doi":"10.15761/nrd.1000169","DOIUrl":"https://doi.org/10.15761/nrd.1000169","url":null,"abstract":"A retrospective clinical audit undertaken at East Surrey looking at the risk assessment targeting modifiable risk factors and management of at-risk population of developing AKI in hospital versus community. The study was done over two 5-week periods over the span of 2 years which included 100 patients. The results concluded that 2 of the highest risk factors of developing AKI in hospital were patient co-morbidities (55%) and nephrotoxic medication (55%) where else hypovolemia (52%) was the biggest risk factor of developing AKI in the community. The results also noted overall better management of AKI in the community than in hospital, particularly regular nephrotoxic medication review (90%), fluid balance monitoring (64%), urine dip (75%) and blood gas on admission (76%). Advanced age (58% above the age of 75) and previous history of AKI are common significant risk factors in developing AKI in both groups. The study led to an action plan of developing the hospital AKI guideline, with tailored focus on risk assessment and prevention, which included streamlining management of patients with AKI using an AKI care bundle as well as creating an AKI electronic alert to identify patients admitted with previous history of AKI","PeriodicalId":160607,"journal":{"name":"Nephrology and Renal Diseases","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114765257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Zomorrodi, Abulfazel Bohluli, F. Kakei, Mohsen Mohammadrahimi
{"title":"Patient and graft survival of deceased donor transplant in one year’s post kidney transplant Experience of single center, what does need for results to be better than this?","authors":"A. Zomorrodi, Abulfazel Bohluli, F. Kakei, Mohsen Mohammadrahimi","doi":"10.15761/nrd.1000152","DOIUrl":"https://doi.org/10.15761/nrd.1000152","url":null,"abstract":"Until this time the best modality for treatment of end stage renal failure (ESRD) is kidney transplantation, but the most important problem with that is shortage of donor. A deceased donor is the main provider of kidney and a relative and unrelative live donor is secondary provider of kidney for transplantation. But in deceased donor in comparing with live donor there is not a time for complete evaluation and almost to be in bad condition for deceased donor so it seems that there will be some difference in deceased and live donor outcome. We investigated patient and graft survival in deceased donor in one year after Transplantation in our center. Material and method: From 2003 until 2018 in our center there were 88 ESRD patients between age of 12 to 67 years 33 females 55males that have been transplanted with deceased donors , donors( between ages 5to 60 years 12 females 35 males) but we just only approached 85 cases of recipients (43 males and 42 females) and investigated for patient and graft survival : all of recipients have been treated with induction of ATG and then triple medicines Sandimune or Tacrolimuse and prednisolone and Imuran Cellcept and operation have been carried out with one team of surgery. Results: 8 cases expired about in first 2 months of operation (8 case in early times) and 77 patients were live in one year (90/58%) and overall 16-allograft loss in one year ,69 allografts survived in one year (81/17%). Conclusion: In our center one-year graft survival was 81/17% and patient survival was 90/58% which results may be comparable with other centers and it seems that the result can be better than this in our center which we will discuss in this paper. *Correspondence to: Afshar Zomorrodi, Professor of urology and kidney transplant surgeon, Head of organ transplantation Department, Imam Reza hospital, Tabriz medical science University, Tabriz -Iran, E-mail: dr_zomorrodi@ yahoo.com","PeriodicalId":160607,"journal":{"name":"Nephrology and Renal Diseases","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123748886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aluma Elkayam, Ahmed Abuleil, T Smmolken, A. Saed, N. Haia, Boshra Nasser, W. Nasser
{"title":"Prematurity-related hypertension in children and adolescents born at the Baruch-Padeh medical center, Poriya, North Israel","authors":"Aluma Elkayam, Ahmed Abuleil, T Smmolken, A. Saed, N. Haia, Boshra Nasser, W. Nasser","doi":"10.15761/nrd.1000178","DOIUrl":"https://doi.org/10.15761/nrd.1000178","url":null,"abstract":"","PeriodicalId":160607,"journal":{"name":"Nephrology and Renal Diseases","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122389877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}