Journal of Functional Morphology and Kinesiology最新文献

{"title":"Effect of Different Reduced Training Frequencies After 12 Weeks of Concurrent Ballistic and Aerobic Training on Muscle Power and Triceps Brachii Muscle Architecture.","authors":"Thomas Mpampoulis, Spyridon Methenitis, Angeliki N Stasinaki, Nikolaos Zaras, Gregory C Bogdanis, Gerasimos Terzis","doi":"10.3390/jfmk10010037","DOIUrl":"10.3390/jfmk10010037","url":null,"abstract":"<p><p><b>Background/Objectives:</b> The aim of the present study was to investigate the effect of two long-term reduced concurrent training frequencies (incorporating power training for the upper and high-intensity interval aerobic training for the lower extremities), in which participants performed one training session every either 7 or 14 days, after 12 weeks of systematic concurrent training on upper extremities' muscle strength, power, and morphology in young females. <b>Methods:</b> After a 12-week concurrent resistance and aerobic training period, participants were assigned into three groups and performed either one training session every 7 days (G7), or once every 14 days (G14), or detraining (GD) for 12 weeks, followed by 12 additional weeks of detraining. <b>Results:</b> Performance and muscle mass increased after the initial 12-week training period. After the reduced training frequency period, bench press 1-RM and aerobic power remained unchanged in G7 and decreased significantly in G14 (-5.9 ± 4.9%; -1.4 ± 4.5%). Muscle power and muscle thickness of the triceps branchii long head decreased significantly in G7 (-9.8 ± 7.7%; -0.9 ± 0.6%; respectively, <i>p</i> < 0.05) and G14 (-10.9 ± 7.6%; -2.8 ± 2.7%, respectively, <i>p</i> < 0.05), without significant differences between groups (<i>p</i> > 0.05). <b>Conclusions:</b> In conclusion, 12 weeks of systematic concurrent resistance (upper extremities) and aerobic training (lower extremities) induced significant improvements in upper extremities muscle power/strength and muscle architecture characteristics. Both reduced training frequencies led to significant reductions in power performance. Thus, performing one training session every 2 weeks for 3 months may preserve 90 to 95% of the muscle power/strength, aerobic power and 72% of muscle mass adaptations achieved with systematic concurrent training. However, greater preservations in the above parameters could be observed if the training frequency is one training session per week.</p>","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":"10 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Effects of Foam Rolling and Stretching on Physical Performance and Self-Perceived Fatigue in Young Football Players.","authors":"Elzan Bibić, Valentin Barišić, Borko Katanić, Andrii Chernozub, Nebojša Trajković","doi":"10.3390/jfmk10010036","DOIUrl":"10.3390/jfmk10010036","url":null,"abstract":"<p><p><b>Background/Objectives</b>: The aim of this study was to examine the acute effects of foam rolling and traditional stretch treatments on physical performance and self-perceived fatigue in youth football players. <b>Methods</b>: The sample of participants consisted of 20 youth football players from the Serbia Under-17 league. Participants were randomly assigned to one of two groups, the Foam group (age: 16.6 ± 1.5 years) or the Stretch group (age: 16.9 ± 1.0 years), with each group consisting of 10 participants. The first measurement (I) was conducted before the match; then, the football players played the match, which was followed by the second measurement (II), and afterward, the groups performed their foam and stretch activities. The third measurement (III) was conducted 2 h after the recovery interventions, and the fourth measurement (IV) was conducted 24 h after the match. Players were tested for the following: linear sprints at 5 m, 10 m, and 20 m, squat jumps (SJs), countermovement jumps (CMJs), and arm-driven countermovement jumps (ACMJs). Participants also completed self-assessment questionnaires on fatigue (Hooper scales) and perceived exertion (Borg scales). <b>Results</b>: A 2 × 4 split-plot ANOVA revealed that there were no differences between the foam rolling and stretching treatments in any parameter of physical performance or self-perceived fatigue. However, a separate within-group analysis showed that the Foam group achieved significantly better sprint times in the third and fourth measurements (2 and 24 h post-match, respectively) compared to measurements taken immediately after the football match. Regarding self-perceived parameters, foam rolling reduced fatigue and stress at 2 and 24 h post-match. On the other hand, the stretching treatment only affected the stress parameter, which was reduced 24 h after the football match. <b>Conclusions</b>: These findings indicate that although there were no significant differences between treatments, foam rolling demonstrated certain advantages compared to stretching. Specifically, foam rolling may offer benefits in enhancing subjective recovery and reducing perceived exertion in young football players. However, these conclusions should be interpreted with caution, as the study was cross-sectional and involved a small sample of young football players.</p>","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":"10 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing Recovery Strategies in Elite Speedskating: A Comparative Analysis of Different Modalities.","authors":"Tomasz Kowalski, Kinga Rębiś, Jadwiga Malczewska-Lenczowska, Andrzej Klusiewicz, Michał Starczewski, Sebastian Klich, Przemysław Kasiak","doi":"10.3390/jfmk10010034","DOIUrl":"10.3390/jfmk10010034","url":null,"abstract":"<p><p><b>Background/Objectives:</b> As short-track speed skaters have to race multiple races to achieve success during competition, optimizing the recovery between efforts is a noteworthy performance determinant. Therefore, we compared three different recovery modalities (active cycling recovery, pneumatic compression boots, and isocapnic breathing protocol) in the context of perceived subjective pain and recovery variables, multiple biochemical and biomechanical indices, CMJ height and power, as well as repeated efforts on the ice track. <b>Methods:</b> Fifteen elite short-track speed skaters (eight males and seven females; age 18.3 ± 1.0 years, height 175.6 ± 7.5 cm, weight 73.7 ± 7.7 kg, 23.8 kg/m², VO₂max 55.5 mL·kg^-1·min^-1: ♂ 58 20 ± 3.6 mL·kg^-1·min^-1; and ♀ 53 ± 4.5 mL·kg^-1·min^-1) completed the study experiment and were included in the analyses. Repeated measures ANOVA with optional post hoc Bonferroni correction was used to assess the association magnitude of changes in variables across the recovery methods. <b>Results:</b> All the investigated protocols were associated with significant changes in multiple recovery indices observed within all the investigated protocols (<i>p</i> ≤ 0.05). However, for this sample, they resulted in analogous effects on subjective variables, hormonal response, creatine kinase, CMJ parameters, and on-ice performance (between-protocol effect: <i>p</i> ≥ 0.002). Changes in creatine kinase were generally higher in males than females (<i>p</i> = 0.05), which might suggest that optimal recovery protocols in short-track are gender-dependent. <b>Conclusions:</b> Since compression and active cycling remain gold standard recovery protocols, a similar response from isocapnic breathing suggests it may be a modality particularly useful in real-world settings.</p>","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":"10 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time Estimation Following an Exhaustive Exercise.","authors":"Tiziana Maci, Mario Santagati, Grazia Razza, Maria Cristina Petralia, Simona Massimino, Sergio Rinella, Vincenzo Perciavalle","doi":"10.3390/jfmk10010035","DOIUrl":"10.3390/jfmk10010035","url":null,"abstract":"<p><p><b>Background/Objectives:</b> Time estimation was investigated in 24 healthy adults, including 12 women and 12 men, before and after an exhaustive exercise. <b>Methods</b>: We compared the ability of estimating time intervals in the range 1 to 5 s using tasks requiring mental counting and tasks that did not allow it. Time estimation and blood lactate levels were evaluated before and at the end of the exercise. <b>Results</b>: We found that the perception of time intervals between 1 and 5 s was affected at the end of the exercise. The observed effects, associated with a significant increase in blood lactate levels, were different in the two types of time estimation used in the present study. When participants had to evaluate the duration of the time interval using mental counting, a significant reduction in the overestimation of time made at rest was observed at the end of exercise. On the other hand, when participants had to assess the difference in duration between two events without the possibility of mental counting, a significant deterioration in performance was observed at the end of the exercise. In both cases, no differences were seen between genders. <b>Conclusions</b>: It could be hypothesized that an increase in blood lactate, acting as a type of physiological arousal, could contribute to the distortion of perceived time intervals. On the other hand, it does not yet seem possible to propose a model to explain the worsening of the perception of time when mental counting is not possible.</p>","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":"10 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular Diseases, Vital Organ Fibrosis, and Chronic Inflammation Associated with High-Intensity and/or High-Volume Exercise Training: Double-Edged Sword Effects of Vigorous Physical Activity in Elderly People and/or in Middle-Age Cancer-Therapy-Treated Patients.","authors":"Pierre A Guertin","doi":"10.3390/jfmk10010033","DOIUrl":"10.3390/jfmk10010033","url":null,"abstract":"<p><p>Cardiotoxicity, cardiovascular diseases (CVDs), hypertension, hepatotoxicity, and respiratory problems occurring several months to several years post-chemotherapy and/or radiotherapy are increasingly documented by scientists and clinicians. Anthracyclines, for example, were discovered in the late 1960s to be dose-dependently linked to induced cardiotoxicity, which frequently resulted in cardiomyopathy and heart failure. Most of those changes have also been associated with aging. While it is well known that exercise can slow down cellular aging processes, lessen the effects of chemotherapy, improve the effectiveness of cancer treatments, and prevent health problems in the general population, it remains unclear how exercise volume or intensity may affect the overall benefits of physical activity on health. For instance, higher rates of sudden cardiac arrest or coronary artery calcification have been found in marathon and ultra-marathon runners. Several additional pathological consequences have also been reported recently on many organs of those athletes. This review reports the most recent evidence suggesting that excessive intensity and/or volume may have deleterious effects on health. These findings are in clear contrast with the popular belief that all forms of physical activity can generally reduce the pathological changes associated with aging or cancer therapies. In conclusion, high-intensity training (HIT) and/or high-volume training (HVT) should not be recommended for middle-age and elderly people who have had cancer therapies or not in order to avoid an exacerbation of the consequences of aging or long-term cancer treatment effects on vital organ structures and functions.</p>","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":"10 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relative Age Effect (RAE) According to Norm Values on Anthropometric Performance and Physical Fitness in 9-11-Year-Old Children.","authors":"Artan R Kryeziu, Bujar Begu, Dana Badau, Astrit Iseni","doi":"10.3390/jfmk10010032","DOIUrl":"10.3390/jfmk10010032","url":null,"abstract":"<p><strong>Objectives: </strong>The main purpose of this study is to identify the relative effect of age (RAE) according to norm values on the anthropometric performance and physical fitness of children between the ages of 9 and 11 years. The data, namely the percentiles of anthropometric parameters and physical fitness, are relevant for identifying the RAE in relation to gender and the month of birth in children.</p><p><strong>Methods: </strong>For the sample in this study, 1185 young people from Kosovo were enrolled, including 626 males and 559 females aged 9-11 years. The gathered data were assessed via the EUROFIT methodology, which takes into account comparisons based on the quartile of birth and the relative age effect (RAE).</p><p><strong>Results: </strong>The results of the data show us that there are significant differences in the RAE among children born in Q2 at the age of 9 years, especially in boys, as well as significant differences in the height variable at the <0.005 significance level. Others factors did not show significant differences, for example, variables that are indicators of physical fitness. For both boys and girls born in Q1, significant differences were mainly found in the indicators of explosive strength, flexibility, static strength, speed, and agility, with a level of significance of <i>p</i> < 0.001, while other indicators did not show significant differences. In addition, there was a significant difference the ratio between genders at the <i>p</i> < 0.001 and <i>p</i> < 0.005 levels, mainly among those born in Q1 and Q2. Similarly, at 10 years of age, children who were born earlier in the year had better scores, although the large disparities were more noticeable between quartiles than between genders, where the significant differences were mainly in the indicators of explosive strength, speed, and strength at the <i>p</i> < 0.001 level, as well as static strength, agility, and speed at the <i>p</i> < 0.005 level. Significant differences were also found for the indicators in terms of gender. At the age of 11, significant percentiles were mainly found in the quartiles at the beginning of the year for both boys and girls, and significant differences were also found at the <i>p</i> < 0.001 level for RAE between quartiles and gender.</p><p><strong>Conclusions: </strong>By using these data, it will be possible to highlight how males, who have demonstrated notable advantages in anthropometric and physical fitness measures, as well as those born in the first few months of the year, exhibit a relative age effect (RAE) in accordance with gender norm values.</p>","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":"10 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subgroup Characteristics of Middle-Aged and Older Women with Chronic Low Back Pain by Multiple Factors: A Hierarchical Cluster Analysis.","authors":"Ryo Miyachi, Takaaki Nishimura, Masahiro Noguchi, Akio Goda, Hiromichi Takeda, Eisuke Takeshima, Yuji Kanazawa, Tadashi Imai, Wataru Tanaka","doi":"10.3390/jfmk10010030","DOIUrl":"10.3390/jfmk10010030","url":null,"abstract":"<p><strong>Background/objectives: </strong>Chronic low back pain (CLBP) after middle age is a complex multifactorial condition, and subgrouping is recommended to determine effective treatment strategies. Multidimensional data help create new groupings to increase the effectiveness of interventions in middle-aged and older adults with CLBP. This study aimed to investigate the relationship between the factors associated with CLBP after middle age and to create and characterize a new subgroup based on these factors.</p><p><strong>Methods: </strong>A cross-sectional observational study was conducted and included 46 women aged ≥40 years with CLBP who participated in health events. Trunk muscle mass, lumbar movement control ability, autonomic balance, lumbar tenderness threshold, lumbar proprioception, and severity of central sensitization were assessed.</p><p><strong>Results: </strong>Partial correlation analysis revealed a significant negative correlation between lumbar movement control ability and autonomic balance. A significant positive correlation was observed between trunk muscle mass and the lumbar tenderness threshold. Hierarchical clustering analysis identified three subgroups. The cluster 1 participants had low trunk muscle mass, low tenderness threshold, and low severity of central sensitization. The cluster 2 participants had low trunk muscle mass and tenderness threshold and high severity of central sensitization. The cluster 3 participants had high trunk muscle mass and tenderness threshold and were sympathetically predominant. Trunk muscle mass, pressure pain threshold, severity of central sensitization, and autonomic balance were significantly different between the clusters.</p><p><strong>Conclusions: </strong>Three characteristic subgroups were identified. The results contribute to treatment and prevention strategies for middle-aged and older adults with CLBP based on the characteristics of the subgroups rather than a uniform approach.</p>","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":"10 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Rest Intervals on the Force-Velocity Relationship Obtained During the Keiser's 10-Repetition Leg Press Test.","authors":"John Magne Kalhovde, Christian M M Johannessen, Sigmund B Aasen, Espen Tønnessen","doi":"10.3390/jfmk10010031","DOIUrl":"10.3390/jfmk10010031","url":null,"abstract":"<p><p><b>Background:</b> The Keiser 10-rep leg press test protocol employs short inter-repetition rest intervals (2-38 s), raising concerns as to whether athletes perform optimally. <b>Objectives:</b> The aim of this study was to compare the results of the standard Keiser protocol with an identical protocol modified to include a significantly longer inter-repetition rest intervals and to evaluate whether these effects differed between men and women. <b>Methods:</b> A total of 30 athletes (age 17.1 ± 0.9 years, height 177.8 ± 8.8 cm, and body mass 71.9 ± 11.3 kg) performed three separate tests (total of ~900 repetitions) in a Keiser A420 leg press machine, separated by 4 to 8 days. Test day 1 included a 1RM test followed by a 10-repetition force-velocity test with a standard rest intervals. Test days 2 and 3 involved the same test, with either standard short rest intervals or fixed 3 min inter-repetition rest intervals. <b>Results:</b> Increasing inter-repetition rest intervals significantly improved <i>V</i>₀ and <i>P</i>_max for men and <i>V</i>₀ and <i>FV</i>_slope for women. The benefits of longer rest were notably more pronounced in men, particularly at light to moderate loads, where standard Keiser rest intervals are short (2-9 s). However, extending rest intervals beyond approximately 30 s, as applied at higher loads, provided no additional advantages. <b>Conclusions:</b> Longer rest intervals improved force-velocity metrics more in men than women, with the effect being most pronounced at light to moderate loads where standard protocols utilize short rest intervals (2-9 s). These findings suggest that women recover faster than men under these conditions. However, extending rest beyond 30 s at higher loads provides no additional benefits and is counterproductive at maximal loads.</p>","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":"10 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reversing Decline in Aging Muscles: Expected Trends, Impacts and Remedies.","authors":"Matthew Halma, Paul Marik, Joseph Varon, Jack Tuszynski","doi":"10.3390/jfmk10010029","DOIUrl":"10.3390/jfmk10010029","url":null,"abstract":"<p><p><b>Background</b>: Age-related decline in musculoskeletal function is a significant concern, particularly in Western countries facing demographic shifts and increased healthcare demands. This review examines the typical trajectories of musculoskeletal deterioration with age and evaluates the effectiveness of various interventions in preventing or reversing these changes. <b>Methods</b>: The review analyzes documented rates of decline across multiple parameters, including muscle mass, Type II muscle fiber reduction, and decreased motor unit firing rates. It examines evidence from studies on targeted interventions aimed at reversing these trends or preventing further decline. <b>Results</b>: The evidence suggests that multimodal interventions, including strength training can effectively maintain or improve physical function in aging adults. These interventions have shown potential in altering the trajectory of age-related decline in musculoskeletal function. Conclusions. The findings of this review have important implications for healthcare providers and policymakers in addressing the challenges of an aging population. By providing a framework for understanding and addressing age-related physical decline through evidence-based interventions, this review offers potential strategies for reducing healthcare costs and improving the quality of life for older adults.</p>","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":"10 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone Adaptations to a Whole Body Vibration Protocol in Murine Models of Different Ages: A Preliminary Study on Structural Changes and Biomarker Evaluation.","authors":"Ida Cariati, Roberto Bonanni, Cristian Romagnoli, Lucio Caprioli, Giovanna D'Arcangelo, Virginia Tancredi, Giuseppe Annino","doi":"10.3390/jfmk10010026","DOIUrl":"10.3390/jfmk10010026","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Whole body vibration (WBV) is a valuable tool to mitigate physiological adaptations related to age and inactivity. Although significant benefits have been found at the musculoskeletal level, including increased bone mass and reduced muscle atrophy, the underlying biological mechanisms remain largely unknown. Therefore, our study aimed to evaluate the effects of vibratory training on bone tissue in murine models of different age groups by investigating the structural and distribution changes in some crucial biomarkers involved in musculoskeletal homeostasis. <b>Methods</b>: Specifically, 4-, 12-, and 24-month-old mice were trained with a WBV protocol characterized by three series of 2 min and 30 s, interspersed with a recovery period of the same duration, on a 3-weekly frequency for 3 months. At the end of the training, histological and morphometric analyses were conducted, in association with immunohistochemical analysis to investigate changes in the distribution of fibronectin type III domain-containing protein 5 (FNDC5), NADPH oxidase 4 (NOX4), and sirtuin 1 (SIRT1). <b>Results</b>: Our preliminary results showed that WBV improves musculoskeletal health by preserving bone architecture and promoting up-regulation of FNDC5 and SIRT1 and down-regulation of NOX4. <b>Conclusions</b>: Our study confirms vibratory training as a viable alternative to counter musculoskeletal decline in elderly and/or sedentary subjects. Further investigations should be conducted to deepen knowledge in this field and explore the role of other molecular mediators in physiological adaptations to vibration.</p>","PeriodicalId":16052,"journal":{"name":"Journal of Functional Morphology and Kinesiology","volume":"10 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}