{"title":"Registration of successive DSA images using a simple genetic algorithm with a stochastic performance function","authors":"J. Jacq, C. Roux","doi":"10.1109/NEBC.1993.404346","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404346","url":null,"abstract":"The authors present a method aimed at automatic registration of successive images in a sequence of digital subtraction angiographies (DSA). It is based on the search for polynomial warping which minimizes a L/sub 1/ distance between the two images to be registered. The optimization procedure is carried out by a method based on a traditional genetic algorithm with a stochastic fitness function which operates only on randomly selected individuals. Application to the registration of successive DSA images has been made by considering a map of sites in the neighborhoods of contours. Good preliminary results have been obtained in a reasonable processing time on a sequential computer.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"449 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115858755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Magnetic backprojection imaging for the assessment of the vascular lumen","authors":"H. Hong, M. Fox","doi":"10.1109/NEBC.1993.404424","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404424","url":null,"abstract":"The authors point out that blood vessels can operate as electric conductors when small amounts of current are injected. The currents generate magnetic fields which can be detected by Hall effect sensors. By the backprojection of detected magnetic field, the location of the blood stream was obtained with a maximum position error of about /spl plusmn/7.5% in the prototype system. Such magnetic backprojection imaging (MBI) could potentially be utilized to detect the development of atheromatous plaques on the interior lumen of vessels.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115134977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stimulatory effect of He-Ne laser on the ventral motorneurons in crayfish","authors":"M. Merris","doi":"10.1109/NEBC.1993.404388","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404388","url":null,"abstract":"This investigation described used continuous wave He-Ne laser energy (/spl lambda/ = 670 nm) in an attempt to stimulate the ventral nerve cord (VNC) of the crayfish. The VNC was used as a model system analogous to motorneurons of vertebrates. There were significant increases in spontaneous action potential, which normally occur in the VNC, following laser irradiation of 20+ s. The indications are that laser energy at this wavelength and 20+ s duration increases the sensitivity of the nerve cells. The energy required to elicit an electrical response was reduced from that of non-irradiated cells. All indications are that neural tissues have some light sensitivity and that proper wavelength and amplitude could elicit a motor action potential.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127067982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modeling of a compliant arterial stenosis and its effects on arterial pressure and flow dynamics: implications for chaos","authors":"S. Field, G. Drzewiecki","doi":"10.1109/NEBC.1993.404431","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404431","url":null,"abstract":"Two models for a compliant (deformable) arterial stenosis are discussed. These models take into account the pulsatile pressure and flow of the arterial system as well as some inherent nonlinear properties of this system and the stenosis. A mathematical model which was partly simulated on a computer was developed. The other model was an in vitro (physical) model involving a Starling resistor chamber as the stenosis. Initial tests were performed on both models. The results of these tests give some proof to the presences of chaos in the vicinity of a stenosis.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129541567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Muscle mechanics and sensory feedback control","authors":"Jiping He","doi":"10.1109/NEBC.1993.404417","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404417","url":null,"abstract":"It is shown that the intrinsic mechanical properties of muscles are important components for sensory feedback control. The results are obtained through a computer simulation of small perturbation responses of a three joints musculoskeletal control system using either a hypothetical muscle model having constant force-length and force-velocity relations or a muscle model having complex, nonlinear properties as known today. The optimal feedback control matrix is also generated for both cases. It is shown that while it is possible to obtain comparable closed-loop responses, the feedback gains for the simple linear muscle model are much larger than that for the complex nonlinear muscle model.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127487738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wei-chun Chang, M. J. Lindén, S. Robbins, C. Mayott, P. Engler
{"title":"Computer aided stress analysis of the femur with prosthetic hip stem utilizing computed tomography","authors":"Wei-chun Chang, M. J. Lindén, S. Robbins, C. Mayott, P. Engler","doi":"10.1109/NEBC.1993.404415","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404415","url":null,"abstract":"A computer aided analysis method utilizing computed tomography (CT) together with a finite element program to determine the stress patterns in a femur with a total hip prosthesis is discussed. The CT scan data file provide the geometry for the three-dimensional finite element model. The model of femur-prosthesis is automatically generated from the CT data file by a preprocessing procedure which includes an edge detection algorithm to determine the boundaries of the reconstructed cross sectional images of the scanned bone. Formatted input data for ANSYS finite element program is generated by the preprocessor to calculate the stresses and displacements at the nodes and elements of the model. A practical method to transfer the CT data to the CAD/CAM system creating a three-dimensional bone geometry is developed. The edge data generated by the preprocessor are also introduced into a solid modeling package to produce a three-dimensional plastic solid model.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126155578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mean velocities and Reynolds stress measurements around the valves in the Penn State LVAD","authors":"J. Maymir, S. Deutsch, D. Geselowitz, J. Tarbell","doi":"10.1109/NEBC.1993.404379","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404379","url":null,"abstract":"A laser Doppler anemometer (LDA) was used to measure two components of velocity at eight locations around the Bjork-Shiley monostrut artificial valves in a plexiglass model of the Penn State 70 cc electric left ventricular assist device (LVAD). The model was filled with a blood analog fluid which matched the kinematic viscosity of blood. The model was connected to a mock circulatory loop in order to generate physiologic conditions. Two hundred and fifty velocity realizations were obtained during six time windows in the regurgitant phase of the flow cycle. These data were then processed, and the mean velocities and Reynolds turbulent stresses were calculated. The results reveal that a significant regurgitant jet occurs in the minor orifice of both the mitral and aortic valves. The strength of the jet is large enough for hemolysis and blood damage to occur.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122039203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Feature extraction for non-rigid motion analysis using continuity splines","authors":"S. H. Gwydir, H. Buettner, S. Dunn","doi":"10.1109/NEBC.1993.404420","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404420","url":null,"abstract":"Quantitative analysis of neurite outgrowth and growth cone motility provides key information for the development of new therapeutic strategies for treating peripheral nerve injury. The goal of this research is to track the motion of the growth cone through sequential time frames and to provide quantitative analysis of specific neurite modalities. The motion of the growth cone can be characterized as nonrigid, since the contour of the growth cone is constantly deforming. The problem of tracking the motion of nonrigid objects is addressed, and energy-minimizing active contour methods are used to track the motion of the growth cone.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128284588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Romulus, D. Goldman, F. Chen, S. Reisman, A. Malick
{"title":"Automated aerosol testing","authors":"R. Romulus, D. Goldman, F. Chen, S. Reisman, A. Malick","doi":"10.1109/NEBC.1993.404350","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404350","url":null,"abstract":"Aerosol cans have evolved into a more reliable and effective product, but they must meet the requirements of the Food and Drug Administration. The Research and Development Laboratory at Hoffman-La Roche conducts the necessary tests on these drugs. The shot weight test and the dose uniformity test are some of the many tests performed on these products, but the tests are very tedious and repetitive. An automated system is described that will simplify the tests. The different stations of the automated system were tested and the results were found to be satisfactory.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127822452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Marino, E. Halgren, J. Badier, M. Gee, V. Nenov
{"title":"A finite difference model of electric field propagation in the human head: Implementation and validation","authors":"F. Marino, E. Halgren, J. Badier, M. Gee, V. Nenov","doi":"10.1109/NEBC.1993.404406","DOIUrl":"https://doi.org/10.1109/NEBC.1993.404406","url":null,"abstract":"It is shown that a realistic finite-difference computational model for the propagation of electrical fields within the human head can be effectively implemented on a massively parallel computer. Potentially, the model will have not only anatomical accuracy, but also will be applicable to individual subjects automatically using their MRIs and/or CTs. This model has two further advantages. First, it yields the electric field distribution for all points within the head, not only at the scalp. Second, it allows the calculation of electric fields resulting from complex generator configurations without additional processing time, simply by placing additional sources and sinks at locations determined by the individual's MRI. Analytical methods can also model generators as dipole layers with complex geometries as the sum of many individual dipoles. However, the calculation increases proportionally with the number of modelled dipoles, and the placement of dipoles is problematic because the brain is not spherical. The model requires further development before it can be usefully applied to understanding the generation of human EEG.<<ETX>>","PeriodicalId":159783,"journal":{"name":"1993 IEEE Annual Northeast Bioengineering Conference","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1993-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128264825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}