{"title":"The shadow of unjustified surgical interventions in gynecology: Time for transparency, accountability and quality care","authors":"Lobna Ouldamer","doi":"10.1016/j.jogoh.2025.103062","DOIUrl":"10.1016/j.jogoh.2025.103062","url":null,"abstract":"","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 1","pages":"Article 103062"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145458926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marie Charpentier , Caroline Goupille , Flavie Arbion , Sandrine Avigdor , Patrick Michenet , Gilles Body , Lobna Ouldamer
{"title":"Male breast cancer: Insights from a two-center epidemiological analysis","authors":"Marie Charpentier , Caroline Goupille , Flavie Arbion , Sandrine Avigdor , Patrick Michenet , Gilles Body , Lobna Ouldamer","doi":"10.1016/j.jogoh.2025.103057","DOIUrl":"10.1016/j.jogoh.2025.103057","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to explore the clinical, histological, prognostic, and therapeutic aspects of male breast cancer to enhance its management by analyzing associated risk factors.</div></div><div><h3>Methods</h3><div>We retrospectively identified male patients diagnosed with primary breast cancer from 1997 to 2020 at the gynecology departments of CHRU in Tours and the regional hospital in Orléans. Data including epidemiological characteristics, clinical signs, histological details, and treatment outcomes were collected and analyzed.</div></div><div><h3>Results</h3><div>A total of 80 patients with primary breast cancer were included. The median age at diagnosis was 71 years, with significant risk factors such as family history and BRCA2 mutations identified. Most patients presented with palpable masses, and nearly 44 % showed axillary lymph node involvement. The majority of tumors were infiltrating carcinoma, and hormone receptor positivity was high (90 % ER+, 78.8 % PR+). Surgical treatment primarily involved mastectomy, often combined with axillary lymph node dissection. chemotherapy was administered to nearly half of the patients. The 5-year overall survival rate was 80.1 %, with metastases developing in 18.8 % of patients.</div></div><div><h3>Conclusions</h3><div>Male breast cancer remains rare but demonstrates distinct clinical patterns. While management strategies are largely extrapolated from female breast cancer, understanding specific male-associated risk factors and disease characteristics is crucial. Early detection and targeted therapies tailored to male patients may improve outcomes.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 1","pages":"Article 103057"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145345574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retraction notice to “Bilateral uterine artery ligation plus intravenous tranexamic acid during cesarean delivery for placenta previa: a randomized double-blind controlled trial” [J Gynecol Obstet Hum Reprod 48 (2018) 115–119]","authors":"Ahmed M. Abbas , Nahla W. Shady , Hany F. Sallam","doi":"10.1016/j.jogoh.2025.103078","DOIUrl":"10.1016/j.jogoh.2025.103078","url":null,"abstract":"","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 1","pages":"Article 103078"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jerome Lorenzini , Flavie Arbion , Cyril Touboul , Yohann Dabi , Yohan Kerbage , Helene Costaz , Vincent Lavoué , Pierre-François Dupré , Cyrille Huchon , Alexandre Bricou , Geoffroy Canlorbe , Emilie Raimond , Pauline Chauvet , Raffaele Fauvet , Martin Koskas , Gilles Body , Lobna Ouldamer , FRANCOGYN Research Group
{"title":"Evaluating the applicability of ESGO quality indicators in the surgical management of endometrial cancer: Insights from a Francogyn cohort","authors":"Jerome Lorenzini , Flavie Arbion , Cyril Touboul , Yohann Dabi , Yohan Kerbage , Helene Costaz , Vincent Lavoué , Pierre-François Dupré , Cyrille Huchon , Alexandre Bricou , Geoffroy Canlorbe , Emilie Raimond , Pauline Chauvet , Raffaele Fauvet , Martin Koskas , Gilles Body , Lobna Ouldamer , FRANCOGYN Research Group","doi":"10.1016/j.jogoh.2025.103066","DOIUrl":"10.1016/j.jogoh.2025.103066","url":null,"abstract":"<div><h3>Background</h3><div>Endometrial cancer (EC) is a significant health concern in France, necessitating high-quality surgical care to improve patient outcomes. The European Society of Gynaecological Oncology (ESGO) established quality indicators (QIs) to standardize and improve management.</div></div><div><h3>Objective</h3><div>This study evaluates the applicability of ESGO QIs in a real-world setting across 13 centers in France.</div></div><div><h3>Methods</h3><div>This retrospective multicenter cohort study included 2789 patients surgically treated for EC from 2001 to 2020. Demographic data, surgical techniques, adherence to ESGO QIs and trends over time were analyzed. Key indicators analyzed included multidisciplinary team discussions, pre-operative imaging adequacy, surgical techniques employed, and molecular classifications.</div></div><div><h3>Results</h3><div>All patients were discussed in multidisciplinary meetings. Adequate preoperative imaging was achieved in 80.63 % of cases. Minimally invasive surgery was performed in 66.12 % of early-stage patients, showing a significant year-on-year increase from 12 % in 2001 to 85 % in 2020. Among obese patients, 60.78 % underwent laparoscopic procedures, with a conversion rate to open surgery of 3.57 %. Molecular classification results highlighted 35 % of patients as low risk and 32 % as high risk.</div></div><div><h3>Conclusion</h3><div>Our findings indicate that adherence to actual ESGO QIs has substantially improved the quality of surgical management for endometrial cancer in France, despite some areas requiring further enhancement. A coordinated political approach is essential to address existing barriers and ensure consistent implementation of these quality standards across all centers, ultimately aiming to elevate patient care and outcomes in the French healthcare system.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 1","pages":"Article 103066"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145458937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ayman Shehata Dawood , Ahmed M. Abbas , Adel Elgergawy
{"title":"Retraction notice to “A pilot study of a novel technique for hysteroscopic sterilization using the distal ends of a copper-T intrauterine device (Ostialoc)” [J Gynecol Obstet Hum Reprod 49 (2019) 101666]","authors":"Ayman Shehata Dawood , Ahmed M. Abbas , Adel Elgergawy","doi":"10.1016/j.jogoh.2025.103076","DOIUrl":"10.1016/j.jogoh.2025.103076","url":null,"abstract":"","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 1","pages":"Article 103076"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145681290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paula Garcia-Aguilar , Valeria Rolle , Berta Serrano , Carlota Rodó , Itziar Garcia-Ruiz , Pablo Garcia-Manau , Alba Farras , Lidia Illan , Elena Moreno , Marta Dalmau , Eva Roldan , Eloi Sirvent , Joaquin Temprado , Naia Seminario , Nuria Fernández-Hidalgo , Elena Sulleiro , Joan Balcells , Roser Ferrer-Costa , Nerea Maiz , Elena Carreras , Manel Mendoza
{"title":"Effect of SARS-CoV-2 infection on perinatal outcomes by disease severity and trimester of pregnancy: A prospective cohort study","authors":"Paula Garcia-Aguilar , Valeria Rolle , Berta Serrano , Carlota Rodó , Itziar Garcia-Ruiz , Pablo Garcia-Manau , Alba Farras , Lidia Illan , Elena Moreno , Marta Dalmau , Eva Roldan , Eloi Sirvent , Joaquin Temprado , Naia Seminario , Nuria Fernández-Hidalgo , Elena Sulleiro , Joan Balcells , Roser Ferrer-Costa , Nerea Maiz , Elena Carreras , Manel Mendoza","doi":"10.1016/j.jogoh.2025.103058","DOIUrl":"10.1016/j.jogoh.2025.103058","url":null,"abstract":"<div><h3>Introduction</h3><div>To describe the effects of maternal COVID-19 on the incidence of small for gestational age (SGA) newborns and other pregnancy outcomes according to disease severity and trimester of infection.</div></div><div><h3>Material and Methods</h3><div>This was a prospective cohort study conducted at Vall d'Hebron University Hospital between March 2020 and June 2023 which included 404 consecutive single pregnancies with SARS-CoV-2 infection classified by severity and trimester of infection and a reference group of 404 consecutive single pregnancies with no suspicion of SARS-CoV-2 infection. The primary outcome was the incidence of SGA newborns. Secondary outcomes included other adverse perinatal and neonatal outcomes.</div></div><div><h3>Results</h3><div>The rate of SGA newborns was higher in the COVID-19 group, with an adjusted relative risk of 1.60 (95 % CI, 1.03–2.48). The risk was particularly elevated in severe cases and when infection occurred during the first trimester. No association was found between COVID-19 and preeclampsia or spontaneous preterm birth. COVID-19 cases showed a higher risk of iatrogenic preterm birth and maternal intensive care unit admission, particularly in severe cases during the third trimester. When analysed by severity and trimester, adverse neonatal outcomes were more frequent in severe cases and in third trimester.</div></div><div><h3>Discussion</h3><div>Pregnancies affected by COVID-19, especially severe cases and first-trimester infections, were associated with a 60 % increased risk of small for gestational age newborns and also raises the risk of iatrogenic preterm delivery, adverse neonatal outcomes, and maternal intensive care unit admission, particularly in severe cases or third-trimester infections.</div></div><div><h3>Conclusion</h3><div>Healthcare providers should remain vigilant about the risk of adverse pregnancy outcomes in severe cases of COVID19.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 1","pages":"Article 103058"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145370285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From policy to practice in cervical cancer prevention in Reunion Island","authors":"Pauline Ferreira , Meoin Hagege , Phuong Lien Tran","doi":"10.1016/j.jogoh.2025.103067","DOIUrl":"10.1016/j.jogoh.2025.103067","url":null,"abstract":"","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 1","pages":"Article 103067"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145477021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Dürr , P. Berveiller , N. Ramdane , H. Behal , L. Ghesquière , L. Benoit , G-E Roth , N. Sananès , C. Garabedian
{"title":"Is sonographic measurement of head–perineum distance useful for predicting a need for instrument change in vacuum-assisted delivery?","authors":"B. Dürr , P. Berveiller , N. Ramdane , H. Behal , L. Ghesquière , L. Benoit , G-E Roth , N. Sananès , C. Garabedian","doi":"10.1016/j.jogoh.2025.103059","DOIUrl":"10.1016/j.jogoh.2025.103059","url":null,"abstract":"<div><h3>Background</h3><div><em>–</em> Use of ultrasound before operative vaginal delivery (OVD), especially head-perineum distance (HPD) measurement, has shown promising results in the prediction of vacuum-assisted delivery failure. However, the studies were monocentric and there was variation in reported thresholds.</div></div><div><h3>Objectives</h3><div>To assess HPD measurement as a predictor of the failure of vacuum-assisted delivery, requiring an instrument change.</div></div><div><h3>Study design</h3><div>Multicenter, retrospective cohort study in three tertiary maternity hospitals in France, from January 2019 to December 2020. Analyses included all vacuum-assisted delivery attempts in singleton pregnancies of ≥ 34 weeks gestation and for which an ultrasound HPD measurement was available. Vacuum deliveries were classified as success or failure (i.e., leading to an instrument change).</div></div><div><h3>Results</h3><div>- Among 23,974 deliveries, vacuum delivery was performed in 2,432 cases (10.1 %) among which 1,197 (49.2 %) had HPD measurements. Instrument change occurred in 123 (10.3 %). The area under the curve for predicting the failure of a vaginal delivery with vacuum according to HPD measurement was 0.58, smaller in the success group (40.1 ± 12.6 mm vs 43.3 ± 10.9 mm, p <0.001). After multivariable analysis, gestational age and HPD were significantly associated with OVD failure (respectively, OR(95 %CI) 1.26 (1.05-1.51), p=0.015, 1.14 (1.04–1.25), p=0.004); whereas fetal head position did not reach the significance level (p=0.06). However more failure were observed in case of transverse position compared to anterior position (ORa = 2.10 (1.13 to 3.90)).</div></div><div><h3>Conclusion</h3><div>- In our multicenter and retrospective study, HPD measurement has a low predictive value for the need for instrument change in vacuum-assisted OVD. It will be interesting to test mix models including maternal and sonographic parameters.</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 1","pages":"Article 103059"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145418885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on “Experience in medical treatment of ectopic pregnancy, cesarean scar with three comparative methods: Methotrexate intra-gestational-sac injection, ultrasound-guided KCL injection, and hysteroscopy-assisted resection”","authors":"Wendi Zhao, Min Li, Yijing Chu","doi":"10.1016/j.jogoh.2025.103073","DOIUrl":"10.1016/j.jogoh.2025.103073","url":null,"abstract":"","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 1","pages":"Article 103073"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145549505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeremy Boujenah, Bernard Benoit, Reda Djafer, Jacques Raiga, Guillaume Benoist, Bruno Carbonne
{"title":"Fetal monitoring in pregnancies at and beyond 41 completed weeks: Prospective blind observational study of the use of umbilical and middle cerebral artery Doppler","authors":"Jeremy Boujenah, Bernard Benoit, Reda Djafer, Jacques Raiga, Guillaume Benoist, Bruno Carbonne","doi":"10.1016/j.jogoh.2025.103054","DOIUrl":"10.1016/j.jogoh.2025.103054","url":null,"abstract":"<div><h3>Objectives</h3><div>To assess the association of umbilical and middle cerebral artery Doppler, with the need for medical intervention during labor and the occurrence of adverse neonatal outcome in pregnancies at/or beyond 41 weeks.</div></div><div><h3>Methods</h3><div>Prospective, observational study of all pregnant women at 41 weeks and beyond during one year in a single Maternity Unit. Doppler measurements of umbilical artery and middle cerebral artery resistance indices (UA-RI and MCA-RI) and cerebro placental ratio (CPR) were performed at 41 weeks, blinded to the clinical staff. Clinical management of prolonged pregnancy was based on routine antepartum fetal heart rate (FHR) monitoring and ultrasound assessment of oligohydramnios. The main outcome measures were 2 composite criteria: 1) “medical intervention during labor” including any of cesarean delivery for FHR abnormalities and/or need for fetal scalp blood sampling for lactate measurement; and 2) “suboptimal neonatal outcome” including any of 5-min Apgar score < 7, umbilical cord artery pH < 7.15, transfer to neonatal unit or perinatal death. The association between abnormal fetal Doppler and the outcome criteria was assessed.</div></div><div><h3>Results</h3><div>Out of 116 women recruited (12.3 % of all deliveries), 30 (25.9 %) had a medical intervention during labor and 16 (13.8 %) had a suboptimal neonatal outcome. None of antepartum FHR or oligohydramnios were associated with any of the primary outcomes. UA-RI and cerebro-placental ratio were strongly associated with the need for a medical intervention during labor (OR [95 % CI] 13.1 [1.4 – 122.2] and 5.1 [1.3 19.7], respectively) but not with the occurrence or a suboptimal neonatal outcome. If made available to the clinical staff, abnormal fetal Dopplers could have led to 12 additional inductions of labor and to the adequate identification of 13 interventions during labor including 6 cesareans for abnormal FHR.</div></div><div><h3>Conclusion</h3><div>Abnormal fetal Doppler beyond 41 weeks may help to better identify situations at risk for medical intervention for fetal concern during labor. Further studies are necessary to assess its prospective use for the management of prolonged pregnancies</div></div>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":"55 1","pages":"Article 103054"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145312969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}