Xenia Mendez, Ulrike Muench, Corinne P Lewis, Taressa K Fraze
{"title":"Impact of COVID-19 on Trends in Physician Payments from Traditional Medicare from 2017-2021.","authors":"Xenia Mendez, Ulrike Muench, Corinne P Lewis, Taressa K Fraze","doi":"10.1007/s11606-024-08927-z","DOIUrl":"10.1007/s11606-024-08927-z","url":null,"abstract":"","PeriodicalId":15860,"journal":{"name":"Journal of General Internal Medicine","volume":" ","pages":"3279-3282"},"PeriodicalIF":4.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Geduldig, Priya Srikanth, Meg Devoe, Richard Bruno, Samuel T Edwards, Somnath Saha, Brian Chan
{"title":"Baseline Housing Stability Positively Impacts the Effect of an Ambulatory Intensive Care Unit on Decreasing Hospitalization Rates.","authors":"Anna Geduldig, Priya Srikanth, Meg Devoe, Richard Bruno, Samuel T Edwards, Somnath Saha, Brian Chan","doi":"10.1007/s11606-025-09361-5","DOIUrl":"10.1007/s11606-025-09361-5","url":null,"abstract":"","PeriodicalId":15860,"journal":{"name":"Journal of General Internal Medicine","volume":" ","pages":"3263-3266"},"PeriodicalIF":4.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalie Caylor, David W Walsh, Ding Xie, Jennifer L Waller, Thad Wilkins
{"title":"The Impact of COVID-19 on US Academic Medical Centers: Implications for General Medicine Service Lines.","authors":"Natalie Caylor, David W Walsh, Ding Xie, Jennifer L Waller, Thad Wilkins","doi":"10.1007/s11606-025-09439-0","DOIUrl":"10.1007/s11606-025-09439-0","url":null,"abstract":"","PeriodicalId":15860,"journal":{"name":"Journal of General Internal Medicine","volume":" ","pages":"3273-3275"},"PeriodicalIF":4.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143501678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oren Miron, Yael Wolff-Sagy, Mark Levin, Esti Lubich, Jordan Lewinski, Maya Shpunt, Wiessam Abu Ahmad, Ilya Borochov, Doron Netzer, Gil Lavie
{"title":"Fentanyl Initiation Rate Following the Requirement for Specialist Approval.","authors":"Oren Miron, Yael Wolff-Sagy, Mark Levin, Esti Lubich, Jordan Lewinski, Maya Shpunt, Wiessam Abu Ahmad, Ilya Borochov, Doron Netzer, Gil Lavie","doi":"10.1007/s11606-024-09160-4","DOIUrl":"10.1007/s11606-024-09160-4","url":null,"abstract":"<p><strong>Background: </strong>Healthcare organizations attempt to address unwarranted fentanyl use, which often leads to increased risk of addiction and overdose.</p><p><strong>Objective: </strong>To assess the impact of a requirement for a specialist's approval on fentanyl initiation for non-oncological pain.</p><p><strong>Design: </strong>A retrospective cohort study based on observational data.</p><p><strong>Participants: </strong>All 4.4 million non-oncological members of Clalit Health Services were included, from July 20, 2021, to July 19, 2023.</p><p><strong>Main measures: </strong>The rate of fentanyl initiation was assessed before and after the implementation of the requirement for specialist's approval, which was introduced on July 2022, and expanded 6 months later for continued use. A sub-group analysis by age group was performed, and patient characteristics and indications were assessed. We also compared total opioid dispensation in the 6th and 12th months after the implementation with the predicted rate based on pre-implementation rates.</p><p><strong>Key results: </strong>Fentanyl initiation rate in the year before the requirement was 711 per million capita, which decreased following the requirement by - 81% (95% CI: - 77%; - 85%). The decrease attenuated with age. The prevalence of diagnosis with substance abuse disorders at the time of fentanyl initiation decreased from 6 to 3%. In the 6th and 12th months after the requirement was implemented, the morphine milligram equivalent (MME) from dispensation of total opioids was lower than predicted based on pre-implementation rates by 7% and 26%, respectively.</p><p><strong>Conclusions: </strong>Requiring specialist approval for fentanyl initiation for non-oncological chronic pain was associated with a decrease in fentanyl prescription initiations, especially among non-elderly patients. A decrease also occurred gradually in total opioid dispensations, further decreasing following the extension of the requirement to continuous fentanyl. The requirement for specialist approval upon fentanyl initiation and continuous fentanyl may present an effective tool for limiting the use of fentanyl and total opioids in healthcare systems.</p>","PeriodicalId":15860,"journal":{"name":"Journal of General Internal Medicine","volume":" ","pages":"3097-3103"},"PeriodicalIF":4.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ann Elizabeth Montgomery, Kalea Jones, Kashfi Pandit, Aerin J deRussy, Richard E Nelson, Joshua S Richman, Thomas H Byrne
{"title":"Change in Outpatient Care Following Migration Among Veterans with Experience of Housing Instability.","authors":"Ann Elizabeth Montgomery, Kalea Jones, Kashfi Pandit, Aerin J deRussy, Richard E Nelson, Joshua S Richman, Thomas H Byrne","doi":"10.1007/s11606-025-09494-7","DOIUrl":"10.1007/s11606-025-09494-7","url":null,"abstract":"","PeriodicalId":15860,"journal":{"name":"Journal of General Internal Medicine","volume":" ","pages":"3299-3301"},"PeriodicalIF":4.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Don't Induct, Just Start Buprenorphine for Opioid Use Disorder.","authors":"Jared W Klein, Sarah Leyde, Amy J Kennedy","doi":"10.1007/s11606-025-09583-7","DOIUrl":"10.1007/s11606-025-09583-7","url":null,"abstract":"","PeriodicalId":15860,"journal":{"name":"Journal of General Internal Medicine","volume":" ","pages":"2962-2963"},"PeriodicalIF":4.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12463785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Impact of Addiction Consultation and Medication for Opioid or Alcohol Use Disorder on Hospital Readmission.","authors":"Eugene Lambert, Susan Regan, Sarah E Wakeman","doi":"10.1007/s11606-024-09301-9","DOIUrl":"10.1007/s11606-024-09301-9","url":null,"abstract":"<p><strong>Background: </strong>Patients with substance use disorder (SUD) are frequently hospitalized and readmitted. Hospitalization is an opportunity for treatment initiation, including medications for alcohol (MAUD) and opioid use disorder (MOUD). Addiction consult teams are one model for increasing hospital-based SUD treatment.</p><p><strong>Methods: </strong>Retrospective analysis examining adult hospitalizations from 2019 to 2023 at an academic medical center with a robust addiction consult team. We assessed the association of addiction consultation with MOUD or MAUD receipt during admission, and the association of addiction consultation, MOUD or MAUD discharge prescription, or MOUD or MAUD new initiation with 30-day readmission rates in generalized linear models.</p><p><strong>Results: </strong>There were 19,697 admissions for patients with SUD among 10,453 unique patients. Addiction consultation was associated with higher rates of medication receipt during admission (MOUD, 84% vs. 49%, p < 0.001; MAUD, 33.4% vs. 6.0%, p < 0.001) For patients with OUD, MOUD discharge prescription rates doubled among those seen by the consult team (RR, 2.29; 95% CI, (2.02-2.60). For those with AUD, MAUD discharge prescription rates increased several-fold among those seen by the consult team (RR, 9.48; 95% CI, 8.05-11.16). Addiction consultation was associated with reduced risk of readmission (aRR, 0.82; 95% CI, 0.75-0.89). For AUD, discharge MAUD was associated with reduced risk of readmission (aRR, 0.84; 95% CI, 0.72-0.99) as was new MAUD initiation (aRR, 0.78; 95% CI, 0.629-0.977). For OUD, addiction consultation was associated with a reduced risk of readmission (aRR, 0.77; 95% CI, 0.68-0.87) as was newly initiating MOUD and prescribing it at discharge (aRR, 0.46; 95% CI, 0.33-0.46).</p><p><strong>Conclusion: </strong>Addiction consultation is associated with increased MAUD and MOUD receipt and decreased risk of 30-day readmission. MOUD initiation and MAUD initiation are associated with reduced risk of readmission.</p>","PeriodicalId":15860,"journal":{"name":"Journal of General Internal Medicine","volume":" ","pages":"2989-2996"},"PeriodicalIF":4.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12463793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trigeminal Trophic Syndrome of the Forehead: The Art of Observation in Clinical Diagnosis.","authors":"Thomas Le, James Vu, Adrienne Atencio","doi":"10.1007/s11606-025-09753-7","DOIUrl":"10.1007/s11606-025-09753-7","url":null,"abstract":"<p><p>A female patient with a history of herpes zoster ophthalmicus presented with a chronic, right-sided facial ulcer consistent with trigeminal trophic syndrome (TTS), triggered by wound-picking due to concurrent anxiety and depression. TTS is a rare disorder diagnosed clinically and managed with behavioral modification alongside medical treatment.</p>","PeriodicalId":15860,"journal":{"name":"Journal of General Internal Medicine","volume":" ","pages":"3244-3247"},"PeriodicalIF":4.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144731696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marlene Martin, Taylor Baisey, Sasha Skinner, Leslie Ly, Kristin Slown, Kristin Harter, Oanh Kieu Nguyen, Scott Steiger, Leslie W Suen
{"title":"Early Results of Implementing Rapid Methadone Titration for Hospitalized Patients: A Case Series.","authors":"Marlene Martin, Taylor Baisey, Sasha Skinner, Leslie Ly, Kristin Slown, Kristin Harter, Oanh Kieu Nguyen, Scott Steiger, Leslie W Suen","doi":"10.1007/s11606-024-09341-1","DOIUrl":"10.1007/s11606-024-09341-1","url":null,"abstract":"<p><strong>Objectives: </strong>With the increase in illicit fentanyl use in the USA, hospitals face challenges managing opioid withdrawal and opioid use disorder (OUD). To improve opioid withdrawal and OUD treatment among hospitalized patients with daily fentanyl use, we developed a rapid methadone titration (RMT) protocol. We describe development, implementation, and outcomes during the first 12 weeks.</p><p><strong>Methods: </strong>We analyzed electronic health record data of hospitalizations seen by the Addiction Consult Team (ACT) for methadone initiation between 9/11/23 and 12/3/23. Adults aged 18-64 reporting daily fentanyl use, desiring methadone, and without end-stage organ damage or critical illness were RMT eligible. We characterized patients who received RMT, abstracting demographic and clinical characteristics, adverse events graded by the Common Terminology Criteria for Adverse Events (CTCAE), and methadone and additional full agonist opioid (FAO) dosing. Our primary outcome was adverse events. Secondary outcomes included median time to 100 mg of methadone, FAO dosing, and self-directed discharge.</p><p><strong>Results: </strong>ACT assessed 55 hospitalizations representing 47 patients for RMT eligibility. Among these, 19 (34.5%) hospitalizations representing 17 patients were eligible for and received RMT. Four (21.2%) hospitalizations that received RMT had sedation events, and all were mild or moderate grade by CTCAE. Hospitalizations achieved a median methadone dose of 100 mg by day 6, with FAO doses peaking on day 5. One (5.3%) hospitalization had a self-directed discharge.</p><p><strong>Conclusions: </strong>With careful patient selection and ACT evaluation, a RMT protocol for hospitalized patients with fentanyl use disorder experienced few adverse events other than mild-moderate sedation, even among those receiving FAO and those with concurrent substance use disorders.</p>","PeriodicalId":15860,"journal":{"name":"Journal of General Internal Medicine","volume":" ","pages":"3104-3110"},"PeriodicalIF":4.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yilu Dong, Rachel Drury, Jordan Spillane, Mark W Lodes, Annie C Penlesky, Ryan Hanson, Liliana E Pezzin, Siddhartha Singh, Ann B Nattinger
{"title":"The Ambulatory Diabetes Outreach Program (ADOP): Rigorous Evaluation of a Pharmacist and Nurse-Led Care Model.","authors":"Yilu Dong, Rachel Drury, Jordan Spillane, Mark W Lodes, Annie C Penlesky, Ryan Hanson, Liliana E Pezzin, Siddhartha Singh, Ann B Nattinger","doi":"10.1007/s11606-024-08970-w","DOIUrl":"10.1007/s11606-024-08970-w","url":null,"abstract":"<p><strong>Background: </strong>Although several systematic reviews found that ambulatory diabetes mellitus (DM) interventions involving pharmacists generally yielded better outcomes than the ones that did not, existing studies have limitations in rigor and study design.</p><p><strong>Objective: </strong>To examine the intention-to-treat effects of the Ambulatory Diabetes Outreach Program (ADOP) on participants' A1c values and healthcare utilization over a 52-month follow-up period.</p><p><strong>Design: </strong>Difference-in-differences with staggered adoption. Specifically, we employed the Callaway and Sant'Anna's \"group-time average treatment effect\" estimator using not-yet treated as controls adjusting for patient's age, BMI, sex, race, comorbidity, payor, and socio-economic status.</p><p><strong>Participants: </strong>All patients with at least one ADOP treatment encounter from July 2017 to October 2021, regardless of program completion or length of exposure to the program.</p><p><strong>Intervention: </strong>ADOP, a collaborative population health program led by pharmacists and nurse specialists to provide individualized type 2 DM management and education within a large and diverse health system.</p><p><strong>Main measures: </strong>Patients' A1c values and healthcare utilization, including inpatient admission, inpatient days, and numbers of visits to the emergency department, urgent care, and primary care in recent 6 months.</p><p><strong>Key results: </strong>ADOP participation was associated with an overall average reduction of 1.04 percentage points (95%CI - 1.12, - 0.95) in A1c level. Similar A1c reductions were also observed in the subgroups by sex and race/ethnicity. An average of 2 months were required to reach the overall average effect, which persisted over 4 years. Compared to the respective utilization levels pre-intervention, participants also had average reductions in inpatient admissions by 32.4%, inpatient days by 81.6%, visits to the emergency department by 21.6%, and primary care by 17.9%.</p><p><strong>Conclusions: </strong>The results suggest that a collaborative model of pharmacist and nurse-led type 2 DM intervention was effective in improving A1c outcomes and reducing healthcare utilization in the long term.</p>","PeriodicalId":15860,"journal":{"name":"Journal of General Internal Medicine","volume":" ","pages":"3170-3175"},"PeriodicalIF":4.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}