{"title":"Assessing the Rise in Papillary Thyroid Cancer Incidence: A 38-Year Australian Study Investigating WHO Classification Influence.","authors":"Steven Weller, Cordia Chu, Alfred King-Yin Lam","doi":"10.1007/s44197-025-00354-5","DOIUrl":"10.1007/s44197-025-00354-5","url":null,"abstract":"<p><p>The incidence of thyroid cancer has shown marked increases globally over recent decades. This study investigated how the incidence of papillary thyroid carcinoma (PTC) subtypes and World Health Organisation (WHO) endocrine tumour classification changes have affected overall thyroid cancer incidence recorded in Australia. Using incidence data from the Australian Institute of Health and Welfare cancer registry (spanning 1982 to 2019), this descriptive epidemiological study employed joinpoint regression analysis to assess temporal trends in thyroid carcinoma incidence, focusing on PTC. Results were then compared with WHO endocrine tumour classification changes over the same period. The results showed increasing trends for the classic PTC subtype over the entire 38-year period and for thyroid microcarcinomas post-2003, while a declining trend for the follicular variant of PTC was observed commencing in 2015. Examination of PTC incidence also revealed distinct changes in trends that align with the WHO classification of papillary microcarcinoma as a subtype in 2004 and the reclassification of some encapsulated follicular variant of PTCs to non-invasive follicular thyroid neoplasms with papillary-like nuclear features (NIFTP) in 2016/17. Even when taking these WHO classification changes into account, significant increases in PTC over the last three decades are observed. These findings underscore the shifts in classification driven by improving diagnostic clarity influencing thyroid carcinoma incidence patterns. However, thyroid carcinoma cases in Australia have dramatically increased over the last three decades independent of WHO classification changes, suggesting a genuine increase rather than simply being a direct consequence of improved reporting and diagnostics.</p>","PeriodicalId":15796,"journal":{"name":"Journal of Epidemiology and Global Health","volume":"15 1","pages":"9"},"PeriodicalIF":3.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11772643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sleep Quality Among a Sample of Medical Students and the Association with Academic Performance: An Updated Data.","authors":"Abdulrahman Almalki, Moayad Shehata, Khaled Siddiqui, Hamzah Albulushi, Nawaf Alshehri, Ahmed Aldumri, Saeed Alghamdi, Aya Khasati, Siraj Omar Wali, Omar Ayoub","doi":"10.1007/s44197-025-00345-6","DOIUrl":"10.1007/s44197-025-00345-6","url":null,"abstract":"<p><p>Sleep is influenced by various factors, including social, economic, genetic, and medical factors, and work and study schedules. Medical students are highly susceptible to sleep-related problems. In this study, we aimed to evaluate the sleep patterns and quality of medical students and determine their correlation with academic achievement. This cross-sectional study was conducted at the King Abdulaziz University between November 2022 and April 2023. The participants completed an online questionnaire distributed to all medical students via social media channels. The questionnaire included the Pittsburgh Sleep Quality Index to assess sleep quality and Epworth Sleepiness Scale to measure excessive daytime sleepiness (EDS). Academic performance was self-reported by students based on their grade point average. Of the 274 participants, 54.0% were males with a mean age of 22.81 years. Only 21.5% of students reported normal sleep quality during the previous month, with almost 78.5% reporting poor sleep quality and 40.9% experiencing EDS. Notably, no associations were observed between the sleep quality and sleep-wake patterns and academic performance of the students (p = 0.324 and 0.784, respectively). These findings highlight the substantial prevalence of poor sleep quality and EDS among Saudi medical students, consistent with global trends. Unexpectedly, no significant correlation was observed between sleep quality and student academic performance. These findings suggest that the demanding nature of medical education significantly impacts the sleep patterns and overall well-being of students.</p>","PeriodicalId":15796,"journal":{"name":"Journal of Epidemiology and Global Health","volume":"15 1","pages":"8"},"PeriodicalIF":3.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11772640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancing Global Health Equity: Saudi Arabia's Leadership in Conjoined Twins Care and Humanitarian Outreach.","authors":"Abdullah A Al Rabeeah, Ziad A Memish","doi":"10.1007/s44197-025-00339-4","DOIUrl":"10.1007/s44197-025-00339-4","url":null,"abstract":"","PeriodicalId":15796,"journal":{"name":"Journal of Epidemiology and Global Health","volume":"15 1","pages":"7"},"PeriodicalIF":3.8,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk Factors Associated with Post-COVID-19 Conditions Among Diabetes Patients in the United Arab Emirates.","authors":"Aysha Alkhemeiri, Ziad El-Khatib, Abrar Hassan Alameri, Athari Ahmed AlKaabi, Jeyaseelan Lakshmanan, Niyi Awofeso","doi":"10.1007/s44197-025-00346-5","DOIUrl":"10.1007/s44197-025-00346-5","url":null,"abstract":"<p><strong>Background: </strong>A substantial subset of individuals recovering from the Coronavirus disease 2019 (COVID-19) continues to experience persistent symptoms. Individuals with type 2 diabetes face increased morbidity and mortality following COVID-19 infection. This study aimed to identify risk factors for developing post-COVID-19 conditions among COVID-19 patients with diabetes compared to those without diabetes in the United Arab Emirates.</p><p><strong>Methods: </strong>A retrospective study was conducted on a random sample of 400 patients with confirmed COVID-19 (n = 200/400 patients with diabetes versus n = 200 patients without diabetes). Participants were invited to a telephone interview to assess post-COVID-19 symptoms persisting for at least three months after their initial positive COVID-19 polymerase chain reaction (PCR) test. A total of 167 hospitalized patients participated, including 89 with pre-existing diabetes and 78 without diabetes.</p><p><strong>Results: </strong>The prevalence of self-reported post-COVID-19 conditions among participants with diabetes was 34.9%, compared to 14.1% among those without diabetes. Patients with diabetes reported a significant decline in functional status post-COVID-19, with 34.8% experiencing impaired physical activity and 32.6% reporting pain and discomfort, compared to 15.4% and 11.5%, respectively, among participants without diabetes. Older age and female gender were associated with a higher prevalence of post-COVID-19 conditions in the diabetes group.</p><p><strong>Conclusion: </strong>Patients with diabetes in this study self-reported a higher frequency and severity of post-COVID-19 conditions compared to those without diabetes. Risk factors predisposing to severe post-COVID-19 conditions included female gender, older age, and comorbidities. Self-reported depression was rare in both groups of this cohort.</p>","PeriodicalId":15796,"journal":{"name":"Journal of Epidemiology and Global Health","volume":"15 1","pages":"6"},"PeriodicalIF":3.8,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11746986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rofida Asmally, Abdelmalik A Imam, Abdullatif Eissa, Abubakr Saeed, Ahmed Mohamed, Eahaa Abdalla, Mariam Alazraa M Esmaeel, Mariam Elbashir, Mohamed H Elbadawi, Mohammed Omer, Raghad Eltayeb, Ranya Mohammed, Tibyan Abdalhamed, Tina Merghani
{"title":"Water, Sanitation and Hygiene in a Conflict Area: A Cross-Sectional Study in South Kordofan, Sudan.","authors":"Rofida Asmally, Abdelmalik A Imam, Abdullatif Eissa, Abubakr Saeed, Ahmed Mohamed, Eahaa Abdalla, Mariam Alazraa M Esmaeel, Mariam Elbashir, Mohamed H Elbadawi, Mohammed Omer, Raghad Eltayeb, Ranya Mohammed, Tibyan Abdalhamed, Tina Merghani","doi":"10.1007/s44197-025-00347-4","DOIUrl":"10.1007/s44197-025-00347-4","url":null,"abstract":"<p><strong>Background: </strong>The UN General Assembly recognised the human right to water and sanitation through the sixth SDG in 2010. South Kordofan, a state in southern Sudan, faces WASH challenges due to conflict, geographical factors, and inadequate services, impacting over 600,000 residents. Such conflicts are well known for spreading diseases and disrupting WASH-related practices among displaced individuals.</p><p><strong>Objectives: </strong>The study aimed to evaluate the quality and availability of drinking water, as well as sanitation and hygiene practices in rural South Kordofan. It also sought to identify factors affecting community satisfaction with WASH services and to establish a data-driven basis for future interventions addressing these issues.</p><p><strong>Methods: </strong>A cross-sectional study accompanied a medical mission to South Kordofan, selecting 33 villages from South Kordofan based on healthcare, population, and accessibility. Water samples, patient forms and questionnaires were collected using convenient sampling for targeted villages and for attendants of mobile clinics. Laboratory analyses were conducted on water samples. Descriptive statistics, univariate analysis and logistic regression were used to analyse the data. The used level of significance was 0.05.</p><p><strong>Results: </strong>Out of 784 participants, 60.2% were female. Tube wells/boreholes were the primary water source (68.1%), and most participants (70.9%) lived near their water source (less than 30 min). Dissatisfaction with water services was reported by 56.8%, and satisfaction associated with method of delivery (OR = 0.081, CI = 0.024-0.276)), appearance (OR = 0.299, CI = 0.182-0.489), distance (OR = 0.264, CI = 0.099-0.705), water unavailability (OR = 0.477, CI = 0.297-0.765), and obligation to pay (OR = 0.351, CI = 0.185-0.665). Samples showed high levels of contamination, both microbial and physicochemical. Regarding sanitation, over a third of the participants (41.5%) disposed of children's stool by leaving it outdoors. About 10% of the participants reported having diarrhea during the week before the study. However, about two-thirds of the participants (68.1%) showed good hygienic practices by using soap or detergents for hand washing.</p><p><strong>Conclusion: </strong>The study revealed inadequate WASH services, high microbial contamination, and poor water treatment practices. Paradoxically, many participants expressed satisfaction with water services. Sanitation issues and open defecation persist, emphasizing the need for comprehensive interventions. All these negative consequences can be attributed to the armed conflict which resulted in poor awareness about the safety of drinking water, what safe water looks like and proper hygiene practices. Moreover, these conflicts led to disruption of the economical status leading to the absence of proper water purification infrastructure.</p>","PeriodicalId":15796,"journal":{"name":"Journal of Epidemiology and Global Health","volume":"15 1","pages":"4"},"PeriodicalIF":3.8,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephen Eghelakpo Akar, William Nwachukwu, Oludare Sunbo Adewuyi, Anthony Agbakizua Ahumibe, Iniobong Akanimo, Oyeladun Okunromade, Olajumoke Babatunde, Chikwe Ihekweazu, Mami Hitachi, Kentaro Kato, Yuki Takamatsu, Kenji Hirayama, Satoshi Kaneko
{"title":"Epidemiology of Yellow Fever in Nigeria: Analysis of Climatic, Ecological, Socio-Demographic, and Clinical Factors Associated with Viral Positivity Among Suspected Cases Using National Surveillance Data, 2017-2023.","authors":"Stephen Eghelakpo Akar, William Nwachukwu, Oludare Sunbo Adewuyi, Anthony Agbakizua Ahumibe, Iniobong Akanimo, Oyeladun Okunromade, Olajumoke Babatunde, Chikwe Ihekweazu, Mami Hitachi, Kentaro Kato, Yuki Takamatsu, Kenji Hirayama, Satoshi Kaneko","doi":"10.1007/s44197-025-00341-w","DOIUrl":"10.1007/s44197-025-00341-w","url":null,"abstract":"<p><strong>Background: </strong>Since its resurgence in 2017, Yellow fever (YF) outbreaks have continued to occur in Nigeria despite routine immunization and the implementation of several reactive mass vaccinations. Nigeria, Africa's most populous endemic country, is considered a high-priority country for implementing the End Yellow fever Epidemics strategy.</p><p><strong>Methods: </strong>This retrospective analysis described the epidemiological profile, trends, and factors associated with Yellow fever viral positivity in Nigeria. We conducted a multivariable binary logistic regression analysis to identify factors associated with YF viral positivity.</p><p><strong>Results: </strong>Of 16,777 suspected cases, 8532(50.9%) had laboratory confirmation with an overall positivity rate of 6.9%(585). Predictors of YFV positivity were the Jos Plateau, Derived/Guinea Savanah, and the Freshwater/Lowland rainforest compared to the Sahel/Sudan Savannah; dry season compared to rainy season; the hot dry or humid compared to the temperate, dry cool/humid climatic zone; 2019, 2020, 2021, 2022, and 2023 epidemic years compared to compared to 2017; first, third, and fourth quarters compared to the second; male sex compared to female; age group > = 15 years compared to < 15 years; working in outdoor compared to indoor settings; having traveled within the last two weeks; being of unknown vaccination status compared to being vaccinated; and vomiting.</p><p><strong>Conclusion: </strong>Ecological, climatic, and socio-demographic characteristics are drivers of YF outbreaks in Nigeria, and public health interventions need to target these factors to halt local epidemics and reduce the risk of international spread. Inadequate vaccination coverage alone may not account for the recurrent outbreaks of YF in Nigeria.</p>","PeriodicalId":15796,"journal":{"name":"Journal of Epidemiology and Global Health","volume":"15 1","pages":"2"},"PeriodicalIF":3.8,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11747028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meysam Olfatifar, Fariba Rafiei, Amir Sadeghi, Elnaz Ataei, Mohammad Amin Habibi, Mehdi Pezeshgi Modarres, Zohreh Ghalavand, Hamidreza Houri
{"title":"Assessing the Colorectal Cancer Landscape: A Comprehensive Exploration of Future Trends in 216 Countries and Territories from 2021 to 2040.","authors":"Meysam Olfatifar, Fariba Rafiei, Amir Sadeghi, Elnaz Ataei, Mohammad Amin Habibi, Mehdi Pezeshgi Modarres, Zohreh Ghalavand, Hamidreza Houri","doi":"10.1007/s44197-025-00348-3","DOIUrl":"10.1007/s44197-025-00348-3","url":null,"abstract":"<p><strong>Background: </strong>Colorectal cancer (CRC) has become a significant global concern, presenting formidable challenges to healthcare systems and leading to substantial healthcare expenses. This study examines the projected prevalence and trends of CRC worldwide, encompassing 21 regions and 195 nations.</p><p><strong>Methods: </strong>We employed an illness-death model (IDM) in order to forecast the anticipated prevalence of CRC by the year 2040. To accomplish this, we utilized data retrieved from the Global Health Data Exchange (GHDx) query tool spanning from 1990 to 2021. The primary objective of this study is to furnish sex-specific estimations encompassing various geographical regions.</p><p><strong>Results: </strong>By 2040, the global age-standardized prevalence rate (ASPR) of CRC among the total population is projected to rise, reaching 145.82 per 100,000, which reflects an increase of 8.15%. East Asia is forecasted to have the highest ASPR at 330.17 per 100,000, representing a substantial rise of 94.81%. Notably, the most rapid percentage increase is projected in Andean Latin America, with an anticipated rise of 106.2%. In contrast, many countries, particularly in developed nations, are expected to see a decline in ASPR during this period. The United Arab Emirates is projected to experience the most significant decrease in ASPR, at -86.51%, while Mauritius is anticipated to have the largest increase in CRC prevalence rate, at 226.26%. Globally and regionally, the ASPR among males is expected to remain higher than that among females over the next 21 years.</p><p><strong>Conclusions: </strong>The global prevalence of CRC is increasing, particularly in developing countries, while developed countries are anticipated to observe a declining trend. This highlights the significance of appropriately allocating resources and implementing effective preventive measures, especially in developing nations.</p>","PeriodicalId":15796,"journal":{"name":"Journal of Epidemiology and Global Health","volume":"15 1","pages":"5"},"PeriodicalIF":3.8,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Global Burden and Trends of Legionella spp. Infection-Associated Diseases from 1990 to 2021: An Observational Study.","authors":"Yonghong Zhong, Linfeng Shen, Yan Zhou, Yibo Sun, Xiaofang Fu, Huaqiong Huang","doi":"10.1007/s44197-025-00342-9","DOIUrl":"10.1007/s44197-025-00342-9","url":null,"abstract":"<p><strong>Background: </strong>Legionella infections are a major global health issue, yet there's limited research on their impact and trends. We aimed to systematically analyzed the long-term trends in Legionella spp. infection-associated diseases (LSIADs) burden from 1990 to 2021.</p><p><strong>Methods: </strong>Age-standardized disability-adjusted life years (ASR-DALYs) and age-standardized death rates (ASDRs) of LSIADs from 1990 to 2021 were accessed from the Global Burden of Disease (GBD) 2021, which utilized the Bayesian hierarchical meta-regression tool and the Cause of Death Ensemble model to estimate these metrics. Trends in disease burden across age, sex, region, and Socio-Demographic Index (SDI) levels were estimated using annual percentage changes (EAPCs) and annual percentage changes (APCs).</p><p><strong>Results: </strong>Globally, the ASR-DALYs and ASDRs for LSIADs in 2021 were 24.74 and 0.86 per 100,000, respectively, with the highest rates observed in regions with low SDI. From 1990 to 2021, while the overall burden of LSIADs showed a downward trend, the highest ASR-DALYs (101.85 per 100,000) and ASDRs (8.15 per 100,000) were observed in individuals over 70 years of age, accompanied by a corresponding increase in deaths (EAPCs = 0.17%, 95% CI: 0.09-0.26%). Furthermore, increases in ASR-DALYs and ASDRs for LSIADs were also noted among those aged 15-49 years (EAPCs = 0.43% and 0.57%, respectively) and those aged 50-69 years (EAPCs = 0.14% and 0.09%, respectively).</p><p><strong>Conclusion: </strong>Higher disease burdens and increasing trends have been observed in specific age groups and regions, which require the implementation of water quality management plans, enhanced readiness of health facilities, and improved sanitation infrastructure.</p>","PeriodicalId":15796,"journal":{"name":"Journal of Epidemiology and Global Health","volume":"15 1","pages":"3"},"PeriodicalIF":3.8,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11746996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mai M El-Daly, Arwa A Faizo, Shahad A Madkhali, Nashwa F Aldardeir, Nassrin A Badroon, Norah A Uthman, Rahaf T Alqawas, Ahmed A Mousa, Safaa A Turkistani, Esam I Azhar
{"title":"Study of the Prevalence of Human Papillomavirus Genotypes in Jeddah, Saudi Arabia.","authors":"Mai M El-Daly, Arwa A Faizo, Shahad A Madkhali, Nashwa F Aldardeir, Nassrin A Badroon, Norah A Uthman, Rahaf T Alqawas, Ahmed A Mousa, Safaa A Turkistani, Esam I Azhar","doi":"10.1007/s44197-025-00340-x","DOIUrl":"10.1007/s44197-025-00340-x","url":null,"abstract":"<p><p>Human papillomavirus (HPV), a common sexually transmitted infection, includes over 200 types, some linked to genital warts and various cancers, including cervical, anal, penile, and oropharyngeal cancers. In Saudi Arabia, an estimated 10.7 million women aged 15 years and older are at risk of HPV-related cervical cancer. This study assessed HPV prevalence, genotype distribution, awareness, and health behaviors among females in Jeddah, Saudi Arabia. Pap smear samples were collected from 106 women attending gynecology clinics at King Abdulaziz University Hospital and were analyzed using nested PCR and Sanger sequencing. Results showed a 15.1% HPV positivity rate, with genotypes of HPV 16, 6, and 58 identified. HPV 16 was the most prevalent (43.75%), particularly among women aged 35-44. In addition, over 60% of the participants were unaware of the link between HPV and cervical cancer, or the availability of vaccines, indicating significant knowledge gaps in the population. These findings underscore the urgent need for comprehensive HPV surveillance and targeted public health interventions in Saudi Arabia. This study emphasizes the importance of HPV vaccination programs, increased screening, and educational campaigns to address the high prevalence of high-risk genotypes, particularly HPV 16. Tailored strategies are crucial to reducing HPV-related health risks, especially for high-risk age groups and under-informed populations. The data provide a foundation for improving HPV prevention and reducing the burden of related diseases in the Saudi population.</p>","PeriodicalId":15796,"journal":{"name":"Journal of Epidemiology and Global Health","volume":"15 1","pages":"1"},"PeriodicalIF":3.8,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142978837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Reza Rahmanian Haghighi, Chryso Th Pallari, Souzana Achilleos, Annalisa Quattrocchi, John Gabel, Andreas Artemiou, Maria Athanasiadou, Stefania Papatheodorou, Tianyu Liu, José Antonio Cernuda Martínez, Gleb Denissov, Błażej Łyszczarz, Qian Huang, Kostas Athanasakis, Catherine M Bennett, Claudia Zimmermann, Wenjing Tao, Serge Nganda Mekogo, Terje P Hagen, Nolwenn Le Meur, Jackeline Christiane Pinto Lobato, Giuseppe Ambrosio, Ivan Erzen, Binyamin Binyaminy, Julia A Critchley, Lucy P Goldsmith, Olesia Verstiuk, Jideofor Thomas Ogbu, Laust H Mortensen, Levan Kandelaki, Marcin Czech, Joseph Cutherbertson, Eva Schernhammer, Catharina Vernemmen, Antonio José Leal Costa, Tamar Maor, Dimos Alekkou, Bo Burström, Antonis Polemitis, Andreas Charalambous, Christiana A Demetriou
{"title":"Excess Mortality and its Determinants During the COVID-19 Pandemic in 21 Countries: An Ecological Study from the C-MOR Project, 2020 and 2021.","authors":"Mohammad Reza Rahmanian Haghighi, Chryso Th Pallari, Souzana Achilleos, Annalisa Quattrocchi, John Gabel, Andreas Artemiou, Maria Athanasiadou, Stefania Papatheodorou, Tianyu Liu, José Antonio Cernuda Martínez, Gleb Denissov, Błażej Łyszczarz, Qian Huang, Kostas Athanasakis, Catherine M Bennett, Claudia Zimmermann, Wenjing Tao, Serge Nganda Mekogo, Terje P Hagen, Nolwenn Le Meur, Jackeline Christiane Pinto Lobato, Giuseppe Ambrosio, Ivan Erzen, Binyamin Binyaminy, Julia A Critchley, Lucy P Goldsmith, Olesia Verstiuk, Jideofor Thomas Ogbu, Laust H Mortensen, Levan Kandelaki, Marcin Czech, Joseph Cutherbertson, Eva Schernhammer, Catharina Vernemmen, Antonio José Leal Costa, Tamar Maor, Dimos Alekkou, Bo Burström, Antonis Polemitis, Andreas Charalambous, Christiana A Demetriou","doi":"10.1007/s44197-024-00320-7","DOIUrl":"10.1007/s44197-024-00320-7","url":null,"abstract":"<p><strong>Introduction: </strong>The COVID-19 pandemic overwhelmed health systems, resulting in a surge in excess deaths. This study clustered countries based on excess mortality to understand their response to the pandemic and the influence of various factors on excess mortality within each cluster.</p><p><strong>Materials and methods: </strong>This ecological study is part of the COVID-19 MORtality (C-MOR) Consortium. Mortality data were gathered from 21 countries and were previously used to calculate weekly all-cause excess mortality. Thirty exposure variables were considered in five categories as factors potentially associated with excess mortality: population factors, health care resources, socioeconomic factors, air pollution, and COVID-19 policy. Estimation of Latent Class Linear Mixed Model (LCMM) was used to cluster countries based on response trajectory and Generalized Linear Mixture Model (GLMM) for each cluster was run separately.</p><p><strong>Results: </strong>Using LCMM, two clusters were reached. Among 21 countries, Brazil, the USA, Georgia, and Poland were assigned to a separate cluster, with the mean of excess mortality z-score in 2020 and 2021 around 4.4, compared to 1.5 for all other countries assigned to the second cluster. In both clusters the population incidence of COVID-19 had the greatest positive relationship with excess mortality while interactions between the incidence of COVID-19, fully vaccinated people, and stringency index were negatively associated with excess mortality. Moreover, governmental variables (government revenue and government effectiveness) were the most protective against excess mortality.</p><p><strong>Conclusion: </strong>This study highlighted that clustering countries based on excess mortality can provide insights to gain a broader understanding of countries' responses to the pandemic and their effectiveness.</p>","PeriodicalId":15796,"journal":{"name":"Journal of Epidemiology and Global Health","volume":" ","pages":"1650-1661"},"PeriodicalIF":3.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11652428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}