Journal of Evidence-based Integrative Medicine最新文献

{"title":"Phytochemical and Therapeutic Potential of <i>Citrus grandis</i> (L.) Osbeck: A Review.","authors":"Rusat Jahin Anmol,&nbsp;Shabnam Marium,&nbsp;Fei Tsong Hiew,&nbsp;Wan Chien Han,&nbsp;Lee Kuan Kwan,&nbsp;Alicia Khai Yeen Wong,&nbsp;Farzana Khan,&nbsp;Md Moklesur Rahman Sarker,&nbsp;Siok Yee Chan,&nbsp;Nurolaini Kifli,&nbsp;Long Chiau Ming","doi":"10.1177/2515690X211043741","DOIUrl":"https://doi.org/10.1177/2515690X211043741","url":null,"abstract":"Citrus grandis or Citrus maxima, widely recognized as Pomelo is widely cultivated in many countries because of their large amounts of functional, nutraceutical and biological activities. In traditional medicine, various parts of this plant including leaf, pulp and peel are used for generations as they are scientifically proven to have therapeutic potentials and safe for human use. The main objective of this study was to review the different therapeutic applications of Citrus grandis and the phytochemicals associated with its medicinal values. In this article different pharmacological properties like antimicrobial, antitumor, antioxidant, anti-inflammatory, anticancer, antiepileptic, stomach tonic, cardiac stimulant, cytotoxic, hepatoprotective, nephroprotective, and anti-diabetic activities of the plant are highlighted. The enrichment of the fruit with flavonoids, polyphenols, coumarins, limonoids, acridone alkaloids, essential oils and vitamins mainly helps in exhibiting the pharmacological activities within the body. The vitamins enriched fruit is rich in nutritional value and also has minerals like calcium, phosphorous, sodium and potassium, which helps in maintaining the proper health and growth of the bones as well as the electrolyte balance of the body. To conclude, various potential therapeutic effects of Citrus grandis have been demonstrated in recent literature. Further studies on various parts of fruit, including pulp, peel, leaf, seed and it essential oil could unveil additional pharmacological activities which can be beneficial to the mankind.","PeriodicalId":15714,"journal":{"name":"Journal of Evidence-based Integrative Medicine","volume":"26 ","pages":"2515690X211043741"},"PeriodicalIF":3.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c7/bb/10.1177_2515690X211043741.PMC8527587.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39524176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benefit of OTC Formula Against COVID-19 Is Explained by Selection Bias.","authors":"Harri Hemilä","doi":"10.1177/2515690X211058417","DOIUrl":"https://doi.org/10.1177/2515690X211058417","url":null,"abstract":"Margolin et al. published a study in which they concluded that a multi-component OTC formulation containing vitamin C, vitamin E, vitamin D, zinc, lysine, quercetin, and Quina extract prevented COVID-19. They reported that 9 of the 60 control participants became COVID-19 positive during the 20-weeks follow-up, whereas none of the 53 participants in the OTC regimen group became COVID-19 positive. Participants were not divided into the groups randomly, nor by alternative allocation. Instead, participants of the “test” group decided for themselves to participate in the trial, whereas the “control” participants decided for themselves not to participate. Margolin argues that “subjects of the regimen-compliant test group and the non-compliant control group both met the same set of inclusion criteria”. However, “the same set of inclusion criteria” in this case does not make compliant and non-compliant participants similar. It is highly likely that there are systematic life-style and other differences between people who chose and those who do not chose to participate in intervention trials. In fact, there is empirical evidence for differences in people by willingness and compliance. In the follow-up of the questionnaire-cohort of the Physicians’ Health Study, age-adjusted overall mortality was 19% lower among 59 277 men who were willing to participate, compared with 52 883 men who were not willing to participate in the trial. However, when baseline characteristics were taken into account, the adjusted difference fell to just 5% and was no longer a significant difference. Thus, essentially all of the significant 19% difference was explained by life-style and other differences between the two groups. For example, “those who were willing, tended to be younger, exercise more, and be less likely to have a positive disease history for several major chronic conditions”. Thus, the uniform set of criteria for sending the questionnaire to the large group of male physicians aged 40 to 84 years did not generate to a homogeneous group of men, and within the large group there were substantial systematic differences between those who were willing and those who were not willing to participate in the trial. In epidemiology this phenomenon is called selection bias. The purpose of randomization in randomized controlled trials (RCT) is to form two (or more) groups that do not have any systematic differences between the groups. Thereby the differences between the groups that appear during intervention can be attributed to the particular intervention. There is RCT evidence that vitamin C may influence COVID-19, and that nasal carrageenan influences coronavirus infections. Therefore, randomized trials on OTC treatments for the newcoronavirus andother respiratory viruses should be encouraged. However, comparison of participants who are willing versus notwilling to participate in a trial is fundamentally biased and therefore thefindings of theMargolin study are not a validmeasur","PeriodicalId":15714,"journal":{"name":"Journal of Evidence-based Integrative Medicine","volume":"26 ","pages":"2515690X211058417"},"PeriodicalIF":3.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39610891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cassia Abbreviata Enhances Glucose Uptake and Glucose Transporter 4 Translocation in C2C12 Mouse Skeletal Muscle Cells.","authors":"F D Y Kamga-Simo,&nbsp;G P Kamatou,&nbsp;C Ssemakalu,&nbsp;L J Shai","doi":"10.1177/2515690X211006333","DOIUrl":"https://doi.org/10.1177/2515690X211006333","url":null,"abstract":"<p><strong>Background: </strong>This study aim at assessing <i>C. abbreviata</i> aqueous extracts for its potential to exhibit anti-diabetic activity in skeletal muscle cells. In addition to the toxicological and glucose absorption studies, the action of <i>C. abbreviata</i> extracts on some major genes involved in the insulin signaling pathway was established.</p><p><strong>Methods: </strong>The <i>in vitro</i> cytotoxic effects <i>C. abbreviata</i> was evaluated on muscle cells using the MTT assay and the <i>in vitro</i> glucose uptake assay conducted using a modified glucose oxidase method described by Van de Venter et al. (2008). The amount of GLUT-4 on cell surfaces was estimated quantitatively using the flow cytometry technique. Real time quantitative PCR (RT-qPCR) was used to determine the expression of GLUT-4, IRS-1, PI3 K, Akt1, Akt2, PPAR-γ.</p><p><strong>Results: </strong>Cytotoxicity tests revealed that all extracts tested at various concentrations were non-toxic (LC₅₀ > 5000). Aqueous extracts of leaves, bark and seeds resulted in a dose-dependent increase in glucose absorption by cells, after 1 h, 3 h and 6 h incubation period. Extracts of all three plant parts had the best effect after 3 h incubation, with the leaf extract showing the best activity across time (Glucose uptake of 29%, 56% and 42% higher than untreated control cells after treatment with 1 mg/ml extract at 1 h, 3 h and 6 h, respectively). All extracts, with the exception 500 µg/ml seed extract, induced a two-fold increase in GLUT-4 translocation while marginally inducing GLUT-10 translocation in the muscle cells. The indirect immunofluorescence confirmed that GLUT-4 translocation indeed occurred. There was an increased expression of GLUT-4, IRS1 and PI3 K in cells treated with insulin and bark extract as determined by the RT-qPCR.</p><p><strong>Conclusion: </strong>The study reveals that glucose uptake involves GLUT-4 translocation through a mechanism that is likely to involve the upstream effectors of the PI3-K/Akt pathway.</p>","PeriodicalId":15714,"journal":{"name":"Journal of Evidence-based Integrative Medicine","volume":"26 ","pages":"2515690X211006333"},"PeriodicalIF":3.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2515690X211006333","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25535565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benefit of OTC Formula Against COVID-19-Statistical Analysis Explained.","authors":"Leon Margolin,&nbsp;Jeremy Luchins,&nbsp;Daniel Margolin,&nbsp;Michelle Margolin,&nbsp;Sanford Lefkowitz","doi":"10.1177/2515690X211058421","DOIUrl":"https://doi.org/10.1177/2515690X211058421","url":null,"abstract":"“Our adoption of conservative exposure-and-symptom-presentation values in data analysis may compensate for lacunae in study design and execution. The study emerged from our efforts to protect our patients and staff members from COVID-19 [in the time-frame March-July 2020, when no or very limited effective guidelines or treatments were available]...it is our hope that the study will serve as a basis for future larger-scale studies of enhanced design...While we believe that the stark difference in clinical outcomes between the test and control groups demonstrates the utility of the study formulations, we certainly welcome future extensive prospective studies.”","PeriodicalId":15714,"journal":{"name":"Journal of Evidence-based Integrative Medicine","volume":"26 ","pages":"2515690X211058421"},"PeriodicalIF":3.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/84/61/10.1177_2515690X211058421.PMC8724988.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39611536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"20-Week Study of Clinical Outcomes of Over-the-Counter COVID-19 Prophylaxis and Treatment.","authors":"Leon Margolin,&nbsp;Jeremy Luchins,&nbsp;Daniel Margolin,&nbsp;Michelle Margolin,&nbsp;Sanford Lefkowitz","doi":"10.1177/2515690X211026193","DOIUrl":"https://doi.org/10.1177/2515690X211026193","url":null,"abstract":"<p><strong>Objectives and setting.: </strong>As the lethal COVID-19 pandemic enters its second year, the need for effective modalities of alleviation remains urgent. This includes modalities that can readily be used by the public to reduce disease spread and severity. Such preventive measures and early-stage treatments may temper the immediacy of demand for advanced anti-COVID measures (drugs, antibodies, vaccines) and help relieve strain also on other health system resources.</p><p><strong>Design and participants.: </strong>We present results of a clinical study with a multi-component OTC \"core formulation\" regimen used in a multiply exposed adult population. Analysis of clinical outcome data from our sample of over 100 subjects - comprised of roughly equal sized regimen-compliant (test) and non-compliant (control) groups meeting equivalent inclusion criteria - demonstrates a strong statistical significance in favor of use of the core formulations.</p><p><strong>Results.: </strong>While both groups were moderate in size, the difference between them in outcomes over the 20-week study period was large and stark: Just under 4% of the compliant test group presented flu-like symptoms, but none of the test group was COVID-positive; whereas 20% of the non-compliant control group presented flu-like symptoms, three-quarters of whom (15% overall of the control group) were COVID-positive.</p><p><strong>Conclusions.: </strong>Offering a low cost, readily implemented anti-viral approach, the study regimen may serve, at the least, as a stopgap modality and, perhaps, as a useful tool in combatting the pandemic.</p>","PeriodicalId":15714,"journal":{"name":"Journal of Evidence-based Integrative Medicine","volume":"26 ","pages":"2515690X211026193"},"PeriodicalIF":3.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2515690X211026193","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39154295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Artemisia lactiflora</i> Extracts Prevent Inflammatory Responses of Human Macrophages Stimulated with Charcoal Pyrolysis Smoke.","authors":"Nateelak Kooltheat,&nbsp;Kamonrat Chujit,&nbsp;Kanjana Nuangnong,&nbsp;Nuttikarn Nokkaew,&nbsp;Kingkan Bunluepuech,&nbsp;Kenshi Yamasaki,&nbsp;Moragot Chatatikun","doi":"10.1177/2515690X211068837","DOIUrl":"https://doi.org/10.1177/2515690X211068837","url":null,"abstract":"<p><p><i>Artemisia lactiflora</i>, a Chinese-origin plant, has been reported to have unique phytochemicals responsible for its medicinal properties. The growth of the agricultural industry emits air pollution, which has adverse effects on health. There are limited scientific reports on the biological activities of <i>A. lactiflora</i>. Studies on its activities and mechanisms may provide insight into its use in medicinal purposes to treat those health problems and conditions. In this study, leaves of <i>A. lactiflora</i> were extracted and fractioned with solvents of different polarities. Total phenolics, total flavonoids DPPH^• scavenging, ABTS^•+ scavenging, and cytotoxicity of <i>A. lactiflora</i> were assessed. Anti-inflammatory activities were evaluated by pre-treating macrophages with extract or fractions then induced inflammatory response by coconut shell pyrolysis smoke. Inflammatory responses were assessed by measuring pro-inflammatory genes expression and pro-inflammatory cytokines secretion. Among all extract and fractions of <i>A. lactiflora</i>, butanol fraction has the highest phenolic, flavonoid, and DPPH^• scavenging activity. All extract and fractions significantly down-regulated pro-inflammatory genes expression (<i>RelA, TNF, IL6</i>) and decreased pro-inflammatory cytokines secretion (TNF-α, IL-6), <i>p</i> < 0.0001, compared with pyrolysis smoke-induced macrophages. The ethyl acetate fraction showed the highest anti-inflammatory activity in decreasing pro-inflammatory cytokines secretion. These results may prove the anti-inflammatory activities of <i>A. lactiflora</i> through the inhibition of the NF-κB-dependent pathway. Taken together, this study first reported the anti-inflammatory activities of <i>A. lactiflora</i>. Thus, the plant can be used to prevent and treat inflammatory responses caused by highly oxidative pyrolysis smoke released from the re-utilization of agro-industrial leftovers.</p>","PeriodicalId":15714,"journal":{"name":"Journal of Evidence-based Integrative Medicine","volume":"26 ","pages":"2515690X211068837"},"PeriodicalIF":3.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f8/74/10.1177_2515690X211068837.PMC8725217.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39751036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Triphala on Lipid and Glucose Profiles and Anthropometric Parameters: A Systematic Review.","authors":"Wiraphol Phimarn,&nbsp;Bunleu Sungthong,&nbsp;Hiroyuki Itabe","doi":"10.1177/2515690X211011038","DOIUrl":"https://doi.org/10.1177/2515690X211011038","url":null,"abstract":"<p><strong>Aim: </strong>The efficacy of triphala on lipid profile, blood glucose and anthropometric parameters and its safety were assessed.</p><p><strong>Methods: </strong>Databases such as PubMed, ScienceDirect, Web of Science, and Thai Library Integrated System (ThaiLIS) were systematically searched to review current evidence of randomized controlled trials (RCT) on triphala. RCTs investigating the safety and efficacy of triphala on lipid profile, blood glucose and anthropometric parameters were included. Study selection, data extraction, and quality assessment were performed independently by 2 authors.</p><p><strong>Results: </strong>Twelve studies on a total of 749 patients were included. The triphala-treated groups showed significantly reduced low-density lipoprotein-cholesterol, total cholesterol and triglyceride in 6 studies. Five RCTs demonstrated triphala-treated groups led to statistically significant decrease in body weight, body mass index and waist circumference of obese patients. Moreover, triphala significantly decreased fasting blood glucose level in diabetic patients but not in people without diabetes. No serious adverse event associated with triphala was reported during treatment.</p><p><strong>Conclusions: </strong>This review summarized a current evidence to show triphala might improve the lipid profile, blood glucose, the body weight, body mass index and waist circumference under certain conditions. However, large well-designed RCTs are required to confirm this conclusion.</p>","PeriodicalId":15714,"journal":{"name":"Journal of Evidence-based Integrative Medicine","volume":"26 ","pages":"2515690X211011038"},"PeriodicalIF":3.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2515690X211011038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38898097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can the Multi-Theory Model (MTM) of Health Behavior Change Explain the Intent for People to Practice Meditation?","authors":"Manoj Sharma,&nbsp;Matthew Asare,&nbsp;Ram Lakhan,&nbsp;Amar Kanekar,&nbsp;Vinayak K Nahar,&nbsp;Sheniz Moonie","doi":"10.1177/2515690X211064582","DOIUrl":"https://doi.org/10.1177/2515690X211064582","url":null,"abstract":"<p><p>Meditation is gaining popularity as adjuvant therapy for many chronic ailments, mental well-being, and spiritual growth. Behavioral theories have been underutilized in understanding meditation behavior. This study aimed to test if a fourth-generation multi-theory model (MTM) could explain the intent for starting and maintaining meditation behavior in a sample of US adults. A face and content valid 48-item instrument based on MTM was administered in a cross-sectional design through an online survey (n = 330). Internal consistency (Cronbach's alpha > 0.70) and construct validation using structural equation modeling of the subscales were all acceptable. Hierarchical multiple regression revealed that, after controlling for demographic covariates, the MTM constructs of participatory dialogue (β  =  0.153; <i>P</i>  =  .002) and behavioral confidence (β  =  0.479; <i>P</i> < .001) were statistically significant in predicting intent for starting meditation behavior and accounted for 32.9% of the variance. Furthermore, after controlling for demographic covariates, the MTM constructs of emotional transformation (β  =  0.390; <i>P</i> < .001) and changes in the social environment (β  =  0.395; <i>P</i> < .001) were statistically significant and accounted for 52.9% of the variance in the intent for maintaining meditation behavior. Based on this study, it can be concluded that MTM offers a pragmatic framework to design, implement, and evaluate evidence-based (theory-based) meditation behavior change interventions.</p>","PeriodicalId":15714,"journal":{"name":"Journal of Evidence-based Integrative Medicine","volume":"26 ","pages":"2515690X211064582"},"PeriodicalIF":3.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/41/8e/10.1177_2515690X211064582.PMC8671666.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39580713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Structured Yoga Program on Stress and Professional Quality of Life Among Nursing Staff in a Tertiary Care Hospital of Delhi-A Small Scale Phase-II Trial.","authors":"Suprakash Mandal, Puneet Misra, Gautam Sharma, Rajesh Sagar, Shashi Kant, S N Dwivedi, R Lakshmy, Kiran Goswami","doi":"10.1177/2515690X21991998","DOIUrl":"10.1177/2515690X21991998","url":null,"abstract":"<p><strong>Background: </strong>Nursing staff suffer from various level of stress and burnout. We aimed to assess the effect of 12 weeks of structured yoga on stress and the professional quality of life among nursing staff.</p><p><strong>Design and method: </strong>An open-label, phase-II randomized clinical trial was undertaken considering a sample size of convenience was done. In service nursing staff were randomized (1:1) to intervention group and wait-list control group. Primary outcome was perceived stress which was measured by Perceived Stress Scale (PSS). Secondary measures were professional quality measured by Professional Quality of Life (ProQOL) scale, blood pressure, serum cortisol, and high-sensitive C-reactive protein. Both the per-protocol and intention to treat analysis was done.</p><p><strong>Results: </strong>Total 113 participants were allocated to intervention group (n = 58, mean = 35 years, SD = 7.9 years) and wait-list control group (n = 55, mean = 32.5 years, SD = 6.8 years). After 12 weeks, 19 participants of intervention group and 32 participants of wait-list control group were included in the per-protocol analysis. Follow-up mean PSS score was 15.4 (95% CI 12.6-18.2, SD 5.8) in intervention group, 20.7 (95% CI 19.7-21.7, SD 2.8) in wait-list control group (p-value < 0.0001). The other parameters didn't differ between the groups and from baseline to end line too.</p><p><strong>Conclusions and relevance: </strong>The finding showed supervised structured yoga may be efficacious to reduce stress. Studies with larger sample size are needed to confirm the findings.</p><p><strong>Trial registration: </strong>It was approved by the Institute Ethics Committee (Reference no: IECPG-543/20.12.2017, RT-57/31.01.2018) and was registered prospectively in the Clinical Trial Registry of India prospectively (No. CTRI/2018/02/012206).</p>","PeriodicalId":15714,"journal":{"name":"Journal of Evidence-based Integrative Medicine","volume":"26 ","pages":"2515690X21991998"},"PeriodicalIF":3.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/10/0b/10.1177_2515690X21991998.PMC7882766.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25354256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parent-Child Mindfulness-Based Training: A Feasibility and Acceptability Study.","authors":"Courtney H Guenther, Rebecca L Stephens, Macy L Ratliff, Sarah J Short","doi":"10.1177/2515690X211002145","DOIUrl":"10.1177/2515690X211002145","url":null,"abstract":"<p><p>Stress in young children can interfere with academic achievement. To help address stress and aid in developing beneficial lifelong coping skills, educational systems are more widely incorporating programs that teach social and emotional regulation, such as mindfulness-based programs. The effects of these programs may be strengthened through parental support in the home environment. This study examined the feasibility and acceptability of a new Parent-Child Mindfulness-Based Training (PC-MBT) program, which delivered mindfulness-based training to parents and children simultaneously in the home environment. This study also implemented a working memory training after PC-MBT to assess the feasibility of completing two trainings sequentially. Healthy children, ages 8-10 (<i>n</i> = 14), and their parents participated in the PC-MBT program. They met with an instructor at home and online each week for 6 weeks and were provided resources including books, worksheets, audio recordings, and daily practices to reinforce mindfulness skills. A control group (<i>n</i> = 8) participated in the working memory training only. All PC-MBT and control children, except one, participated in the working memory training. All PC-MBT assigned families completed the PC-MBT program, and a majority utilized all types of the mindfulness training materials. A majority of participants also reported high levels of enjoyment and understanding of the PC-MBT program. This study establishes the feasibility and acceptability of the PC-MBT program and lays the foundation for future studies to assess program efficacy in healthy and clinical populations as well as the utility of PC-MBT to improve engagement and outcomes of other cognitive training programs.</p>","PeriodicalId":15714,"journal":{"name":"Journal of Evidence-based Integrative Medicine","volume":"26 ","pages":"2515690X211002145"},"PeriodicalIF":3.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5a/dc/10.1177_2515690X211002145.PMC8082986.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38905520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}