Kyala O Shabani, Ayangaifiok M Akpan, Isaac Appiah, Austin M Seymour, Worlanyo E Gato
{"title":"Investigation of the pancreatic toxicological effects of oral ingestion of perfluorobutanesulfonic acid (PFBS) in Sprague-Dawley rats.","authors":"Kyala O Shabani, Ayangaifiok M Akpan, Isaac Appiah, Austin M Seymour, Worlanyo E Gato","doi":"10.1080/10934529.2025.2511411","DOIUrl":"10.1080/10934529.2025.2511411","url":null,"abstract":"<p><p>PFBS (perfluorobutanesulfonic acid) are surfactants in several household products, including drinking water. Exposure to drinking water contaminated with Perfluoroalkyl Substances (PFAs) has been associated with diabetes, hyperglycemia, and/or insulin resistance. The immune system is particularly vulnerable to toxicant exposures, with certain environmental chemicals, such as PFAS, potentially causing immunotoxicity. This study aims to assess PFBS exposure and inflammatory-related effects in the pancreas. Three groups of male Sprague Dawley rats ingested 0 ppm, 50 ppm and 100 ppm of PFBS-diet for ten weeks to achieve study goals. Histopathological analysis showed no significant changes in treated rat pancreases; however, increased weight gain was observed, indicating possible adipogenic effects of PFBS. Treated rats exhibited lower serum glucose levels and higher insulin concentrations, suggesting improved glucose regulation and increased insulin production due to PFBS exposure. PFBS-exposed rats demonstrated reduced serum lipase activity, a marker of pancreatic function. Gene expression analysis revealed upregulated insulin-related genes (Ins1 and Ins2), inflammatory genes (IL6 and TNFα), and pancreatitis-associated genes (CTRC and SPINK1) in treated groups. This study suggests that PFBS exposure could influence glucose regulation, insulin production, and pancreatic inflammation. Further research is essential to decipher the precise mechanisms and clinical implications of PFBS exposure.</p>","PeriodicalId":15671,"journal":{"name":"Journal of Environmental Science and Health Part A-toxic\\/hazardous Substances & Environmental Engineering","volume":" ","pages":"92-101"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing air quality and composition of fine particulate matter (PM<sub>2.5</sub>) in Jackson, MS.","authors":"Amelia Craze Smith, Courtney Roper","doi":"10.1080/10934529.2025.2521899","DOIUrl":"10.1080/10934529.2025.2521899","url":null,"abstract":"<p><p>There are limited studies on air quality in the Southern United States, with even fewer assessing the health impacts of poor air quality on underserved communities. Jackson, the Mississippi state capital, has documented environmental injustices linked to drinking water quality and access to healthcare, but the impact of air pollution is underexplored. Fine particulate matter (PM<sub>2.5</sub>), a complex mixture of air pollution, has associations with systemic health effects and the ability to induce oxidative stress. While federal regulations require monitoring PM<sub>2.5</sub> throughout the United States, there is limited characterization of health relevant components, including black carbon and polycyclic aromatic hydrocarbons (PAHs). This project utilizes PM<sub>2.5</sub> filters to investigate the chemical and toxicological profile of PM<sub>2.5</sub> at two intraurban sites using the dithiothreitol assay to measure oxidative potential and Gas Chromatography - Mass Spectrometry to quantify PAHs. Significant differences between sites in PM<sub>2.5</sub> concentration, oxidative potential, and PAH concentrations was observed. Additional research is needed to determine the potential human health risks that PM<sub>2.5</sub> poses to residents in Jackson, MS, but this work highlights pollutants of interest at levels that exceed similar studies for urban regions, encouraging more attention and action to protect the air of vulnerable populations.</p>","PeriodicalId":15671,"journal":{"name":"Journal of Environmental Science and Health Part A-toxic\\/hazardous Substances & Environmental Engineering","volume":" ","pages":"121-132"},"PeriodicalIF":1.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yue Xiao, Shuai Yuan, Ruxin Luo, Yiling Tang, Xin Wang, Ping Xiang, Bin Di
{"title":"Monitoring of ketamine-based emerging contaminants in wastewater: a direct-injection method and fragmentation pathway study.","authors":"Yue Xiao, Shuai Yuan, Ruxin Luo, Yiling Tang, Xin Wang, Ping Xiang, Bin Di","doi":"10.1080/10934529.2024.2403280","DOIUrl":"10.1080/10934529.2024.2403280","url":null,"abstract":"<p><p>The ketamine (KET) and its analogs consumed by humans are becoming emerging contaminants (ECs), as they at present in surface waters after being carried through wastewater systems. Drugs in wastewater can be analyzed using the direct-injection method, a simple wastewater analysis (WWA) method that can provide objective, continuous and nearly to real-time findings. This article describes an ultra-high-pressure liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the simultaneous quantification and confirmation of seven KET-based ECs in wastewater by direct injection. After optimization of the UPLC-MS/MS and sample pretreatment conditions, the method was validated and applied to samples (<i>n</i> = 157) collected from several wastewater treatment plants (WWTPs) in southern China in which KET had the highest detection rate. The established direct-injection method was not only simple to perform but also had better sensitivity, shorter detection times, and analyzed more KET-based ECs than currently published methods, meeting the requirements for the monitoring and high-throughput analysis of common KET-based ECs. We also analyzed the fragmentation pathway of KET-based ECs to obtain product ion information on other unknown substances. Additional studies are needed to establish a comprehensive direct-injection screening method of ECs in wastewater on model-based assessment.</p>","PeriodicalId":15671,"journal":{"name":"Journal of Environmental Science and Health Part A-toxic\\/hazardous Substances & Environmental Engineering","volume":" ","pages":"389-402"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142288948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Occurrence and distribution of antibiotic resistance genes in Rivers entering the sea from the South bank of Laizhou Bay, China.","authors":"Xinhua Fu, Dongxia Li, Fujun Peng","doi":"10.1080/10934529.2024.2411774","DOIUrl":"10.1080/10934529.2024.2411774","url":null,"abstract":"<p><p>The distribution of antibiotic resistance genes (ARGs) in Laizhou Bay affects the local socio-economic development. The study aimed to investigate the distribution of ARGs in the rivers that flow into the sea around Laizhou Bay's southern shore. Water and sediment samples were collected from different typical sites of rivers entering the sea in Weifang, including Mi River, Bai Lang River, Yu River, Wei River, Jiaolai River, Xiaoqing River and Di River. The species and abundance of ARGs in the sediments were characterized and quantified by macro-genome high-throughput sequencing technology. The species distribution of ARGs was compared. In two sediment samples and seven water samples, 24 ARGs types and 1244 subtypes of ARGs were detected, in which multidrug-resistant class was the main ARGs type and FBJ murine osteosarcoma viral oncogene homolog B (fosB) was the dominant ARGs. The types of ARG in the top ten of these samples were the same, although the proportion was different. Dominant ARG subtypes accounted for more than 50% of all the nine samples. This article provides basic data support for pollution status and environmental risk assessment as well as remediation of ARGs in rivers entering the sea along the south coast of Laizhou Bay.</p>","PeriodicalId":15671,"journal":{"name":"Journal of Environmental Science and Health Part A-toxic\\/hazardous Substances & Environmental Engineering","volume":" ","pages":"420-427"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evans K Suter, Hilary L Rutto, Tumisang S Seodigeng, Sammy L Kiambi, Wesley N Omwoyo
{"title":"Green isolation of cellulosic materials from recycled pulp and paper sludge: a Box-Behnken design optimization.","authors":"Evans K Suter, Hilary L Rutto, Tumisang S Seodigeng, Sammy L Kiambi, Wesley N Omwoyo","doi":"10.1080/10934529.2024.2331942","DOIUrl":"10.1080/10934529.2024.2331942","url":null,"abstract":"<p><p>Cellulose was isolated from recycled pulp and paper sludge and used to synthesize cellulose nanocrystals. Response surface methodology and Box-Behnken design model were used to predict, improve, and optimize the cellulose isolation process. The optimal conditions were a reaction temperature of 87.5 °C, 180 min with 4% sodium hydroxide. SEM and TEM results revealed that the isolated cellulose had long rod-like structures of different dimensions than CNCs with short rod-like structures. The crystallinity index from XRD significantly increased from 41.33%, 63.7%, and 75.6% for Kimberly mill pulp sludge (KMRPPS), chemically purified cellulose and cellulose nanocrystals, respectively. The TGA/DTG analysis showed that the isolated cellulosic materials possessed higher thermal stability. FTIR analysis suggested that the chemical structures of cellulose and CNCs were modified by chemical treatment. The cellulose surface was highly hydrophilic compared to the CNCs based on the high water holding capacity of 65.31 ± 0.98% and 83.14 ± 1.22%, respectively. The synthesized cellulosic materials portrayed excellent properties for high-end industrial applications like biomedical engineering, advanced materials, nanotechnology, sustainable packaging, personal care products, environmental remediation, additive manufacturing, etc.</p>","PeriodicalId":15671,"journal":{"name":"Journal of Environmental Science and Health Part A-toxic\\/hazardous Substances & Environmental Engineering","volume":" ","pages":"64-75"},"PeriodicalIF":2.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140174959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"<i>Escherichia coli</i> removal in down-flow hanging sponge reactors: insights from laboratory reactor studies.","authors":"Noriko Tomioka, Thao Tran P, Masataka Aoki, Yasuyuki Takemura, Kazuaki Syutsubo","doi":"10.1080/10934529.2024.2384205","DOIUrl":"10.1080/10934529.2024.2384205","url":null,"abstract":"<p><p>Down-flow hanging sponge (DHS) reactors, employed in domestic wastewater treatment, have demonstrated efficacy in eliminating <i>Escherichia coli</i> and other potentially pathogenic bacteria. The aim of this study was to elucidate the mechanism of removal of <i>E. coli</i> by employing a cube-shaped polyurethane sponge carrier within a compact hanging reactor. An <i>E. coli</i> removal experiment was conducted on this prepared sponge. <i>Escherichia. coli</i> level was found to decrease by more than 2 logs after passing through five nutrient-restricted DHS sponges. Conversely, a newly introduced sponge did not exhibit a comparable reduction in <i>E. coli</i> level. Furthermore, under conditions of optimal nutritional status, the reduction in <i>E. coli</i> level was limited to 0.5 logs, underscoring the crucial role of nutrient restriction in achieving effective elimination. Analysis of the sponge-associated bacterial community revealed the presence of a type VI secretion system (T6SS), a competitive mechanism observed in bacteria. This finding suggests that T6SS might play a pivotal role in contributing to the observed decline in <i>E. coli</i> level.</p>","PeriodicalId":15671,"journal":{"name":"Journal of Environmental Science and Health Part A-toxic\\/hazardous Substances & Environmental Engineering","volume":" ","pages":"295-304"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Trajče Stafilov, Robert Šajn, Danica Damčevska, Claudiu Tănăselia
{"title":"Moss biomonitoring of lithogenic impact on the distribution of various chemical elements in the air in the region of Mariovo, North Macedonia.","authors":"Trajče Stafilov, Robert Šajn, Danica Damčevska, Claudiu Tănăselia","doi":"10.1080/10934529.2024.2440690","DOIUrl":"10.1080/10934529.2024.2440690","url":null,"abstract":"<p><p>A study was conducted to investigate the air deposition and explore the distribution of potentially toxic elements in the Mariovo region, North Macedonia, using moss samples as biomonitors of air pollution. The distribution of 44 chemical elements was detected in 20 moss samples collected in the area. The moss samples were analyzed after microwave digestion using inductively coupled plasma - atomic emission spectrometry (ICP-AES) and inductively coupled plasma-mass spectrometry (ICP-MS). It was found that atmospheric deposition for some potentially toxic elements in the moss samples in the study area was influenced only by lithogenic origin. R-mode factor analysis was used to identify and characterize elemental associations. Three factors were separated from the group of macroelements determined by ICP-AES: Factor 1 (Cr, Fe, Ni, V, Al, Zn, Pb, and Li), F2 (Li, Sr, and Ba), and F3 (P, and K); and two associations were separated from the group of trace elements determined by ICP-MS: Factor 1 (Ga, Sc, Ti, Co, Zr, Rb, As, Cs, Ge, Y, Sn, Mo, and rare earth elements - REEs) and Factor 2 (Br, B, Cd, I, and Sb).</p>","PeriodicalId":15671,"journal":{"name":"Journal of Environmental Science and Health Part A-toxic\\/hazardous Substances & Environmental Engineering","volume":" ","pages":"536-549"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of machine learning approach (artificial neural network) and shrinking core model in cobalt (II) and copper (II) leaching process.","authors":"Machodi Mathaba, JeanClaude Banza","doi":"10.1080/10934529.2024.2320600","DOIUrl":"10.1080/10934529.2024.2320600","url":null,"abstract":"<p><p>The leaching laboratory experiment uses the artificial neural network (ANN) to predict and evaluate copper and cobalt recovery. This study aimed to evaluate the efficacy of using the shrinking core model in conjunction with an artificial neural network (ANN) as part of a machine learning strategy to improve the leaching process of cobalt (II) and copper (II). The numerous factors in the leaching process, such as acid concentration, leaching time, temperature, soil-to-solution ratio, and stirring speed, are adjusted using an ANN with several layers, feed-forward, and back-propagation learning methods. These variables are in charge of the high cobalt recovery during the reduced sulfuric acid leaching procedure. The ANN algorithm has 10 hidden layers, 5 input variables describing the leaching parameters, and two neurons as output layers corresponding to copper and cobalt leaching recovery. The optimum conditions were found to be acid concentration of 100 g/L, leaching duration 120 min, temperature 55 °C, soil-to-solution ratio of 1:40 g/mL, and stirring speed 300 rpm. The optimized trained neural networks tested, trained, and validated steps are represented by <i>R</i><sup>2</sup> values of 0.94, 0.99, 0.97, and 0.97, respectively, equating to 97.5% copper recovery and 95.4% cobalt recovery.</p>","PeriodicalId":15671,"journal":{"name":"Journal of Environmental Science and Health Part A-toxic\\/hazardous Substances & Environmental Engineering","volume":" ","pages":"25-32"},"PeriodicalIF":2.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139972089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mercury distribution and contamination in the soils of the Mitrovica region, Republic of Kosovo.","authors":"Milihate Aliu, Robert Šajn, Trajče Stafilov","doi":"10.1080/10934529.2024.2331944","DOIUrl":"10.1080/10934529.2024.2331944","url":null,"abstract":"<p><p>The study was carried out to define the distribution of mercury in surface soils in the Mitrovica region, Republic of Kosovo and to assess the level and extent of contamination. A total of 156 soil samples were collected from a depth of 5 cm at each grid point of 1.4 × 1.4 km in an area of 301.5 km<sup>2</sup>. The mercury content was found to be between 0.02 mg/kg and 11.16 mg/kg. The average Hg content (0.49 mg/kg) exceeded the mean content in European (0.037 mg/kg) and world (0.06 mg/kg) soils by 13.2 and 8.2 times, respectively. From the calculated enrichment factors (EF) and the geo-accumulation index (I-geo), as well as from the distribution map of Hg content, it is evident that the soils of the study area are highly contaminated with mercury, with extremely high enrichment of Hg in the soils of Zone I, which was classified as the most contaminated zone with Hg and other potentially toxic elements in the study area as well as in the towns of Zveçan and Mitrovica. The higher Hg content is of anthropogenic origin, mainly due to lead and zinc mining and metallurgical activities in the study area. The mercury levels were also found to exceed the New Dutch List target value (0.3 mg/kg) in 90 km<sup>2</sup> of the study area.</p>","PeriodicalId":15671,"journal":{"name":"Journal of Environmental Science and Health Part A-toxic\\/hazardous Substances & Environmental Engineering","volume":" ","pages":"76-86"},"PeriodicalIF":2.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140193837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phytotoxicity of the aqueous solutions of some dishwashing detergents for dishwashers with phosphonates and without phosphates.","authors":"Nataliia Tkachuk, Liubov Zelena","doi":"10.1080/10934529.2025.2450920","DOIUrl":"10.1080/10934529.2025.2450920","url":null,"abstract":"<p><p>The influx of insufficiently purified or untreated domestic wastewater into aquatic ecosystems raises the question of the production of environmentally friendly detergents. The purpose of this work was to investigate the toxicity of phosphonate-containing and phosphate-free dishwashing detergents for dishwashers according to the phytotest with a garden cress (<i>Lepidium sativum</i> L.). Dishwashing detergents for dishwashers (\"All in 1\"), widely available in the retail network of Ukraine, were used in concentrations the aqueous solutions from 0.005% to 10.0% for their effect on test indicators of garden cress: energy of seed germination, seed germination and biometric and morphometric indicators of seedlings, which were processed statistically. Some phytotoxic indices were determined for the tested aqueous solutions. It was established that the studied solutions of both phosphonate-containing and phosphate-free detergents are extremely and high toxic according to the calculated indices. The obtained data indicate the danger of the investigated detergents for the hydrosphere, the need to replace with a less toxic agents, in particular, based on biosurfactants.</p>","PeriodicalId":15671,"journal":{"name":"Journal of Environmental Science and Health Part A-toxic\\/hazardous Substances & Environmental Engineering","volume":" ","pages":"574-582"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142949987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}