Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)最新文献
{"title":"Theoretical and numerical comparisons between Laplace's solution and Poisson's solution to the forward problem for a finite right circular cylinder [EIT image reconstruction]","authors":"F. Kleinermann, N. J. Avis, F. Alhargan","doi":"10.1109/IEMBS.1998.745628","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.745628","url":null,"abstract":"This paper shows that the full analytical solution derived by the mode matching technique for a finite right circular cylinder using Laplace's equation with inhomogeneous boundary conditions reduces to the full analytical solution derived by the Green's function technique for Poisson's equation using homogeneous boundary conditions when two identical rectangular electrodes are arbitrarily placed on the curved surface of the cylinder. Numerical comparisons between the full solution to Laplace's equation and a reduced form in terms of computed potentials on some points and reconstruction of equipotentials for a polar drive configuration are also presented.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117293704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Sugawara, K. Kimura, K. Misawa, J. Arisawa, O. Igarashi
{"title":"Study on electro-bactericidal effect of the metal coating flat sheet membrane for Pseudomonas aeruginosa","authors":"T. Sugawara, K. Kimura, K. Misawa, J. Arisawa, O. Igarashi","doi":"10.1109/IEMBS.1998.745637","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.745637","url":null,"abstract":"A newly designated metal coating flat sheet membrane was examined for bactericidal activity using Pseudomonas aeruginosa which was recognized as a pathogen to opportunistic infection in hospitals. After the bacteria were artificially trapped into the membrane, an electric current was passed through the surface of the membrane. More than 90% of bacteria were reduced by the passing electric current, comparing with non-electric current control. The kinds of electric current were also tested for their bactericidal activities. Both direct current (DC) and alternating current (50 Hz AC) showed same bactericidal activity for Pseudomonas aeruginosa. Furthermore, steam was observed when an electric current was applied. From these observations, we considered that the application of DC or 50 Hz AC electric current to the metal coating flat sheet membrane could sterilize bacteria which was mechanically trapped, due to heat generation with electric current application.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129522968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unsupervised fuzzy clustering analysis of fMRI series","authors":"M. Fadili, S. Ruan, D. Bloyet, B. Mazoyer","doi":"10.1109/IEMBS.1998.745515","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.745515","url":null,"abstract":"The potential of an fMRI data analysis strategy using a paradigm independent unsupervised fuzzy clustering is presented. The power of the method is demonstrated to discriminate different types of responses without prior knowledge relative to the paradigm in contrast with classic statistical methods which require a priori knowledge about the stimulus. Different performance measure functions are proposed to solve the cluster validity problem and to detect the number of substructures present in the data. The results are presented on both simulated data (with Contrast to Noise Ratios similar to those observed in fMRT), and in vivo EPI data for a motor paradigm. This new data analysis procedure may be very useful for optimization of data analysis and quality in fMRI.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128215701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kyeong-Min Kim, D. Lee, June-Key Chung, M. Lee, Yong Jin Kim
{"title":"Noninvasive measurement of left ventricular contractility using gated myocardial SPECT and arterial pressure tonometer","authors":"Kyeong-Min Kim, D. Lee, June-Key Chung, M. Lee, Yong Jin Kim","doi":"10.1109/IEMBS.1998.745960","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.745960","url":null,"abstract":"For the estimation of left ventricular (LV) contractility, the fully noninvasive measurement of the maximum elastance (E/sub max/) from the steady-state single loop of end systolic pressure volume relation (ESPVR) is attempted. For 32 patients with coronary artery disease, we performed the gated myocardial SPECT with the simultaneous measurement of radial artery pressure using automated tonometer. The left ventricular volume generated from quantitative gated SPECT (QGS) program of SPECT and the central aortic pressure transferred from radial artery pressure measured by automated tonometer were used to make a pressure-volume (PV) loop. With a single PV loop, E/sub max/, was calculated using (1) single PV loop estimation method based on the consistency of normalized elastance curve and (2) regression method based on time-linearity of elastance, respectively. The values of E/sub max/ by the first method were distributed within the range (2.3-5.3) and showed the independence on calculation trials and initial condition for iterative calculation. Normalized elastance curves were consistent for all patients. The E/sub max/ and V/sub 0/ for PV data from sequential gated SPECT acquisition showed the consistent value, respectively (r=0.91 for E/sub max/, r=0.99 for V/sub 0/). The values of E/sub max/ by the second method were within (0.7-5.1) and showed the linear relationship (E/sub max normalized/=2.15/spl times/E/sub max linear/+0.45, r=0.64, p<0.001) with E/sub max/ by the first method. Despite of the lack of comparison with multiple PV loop method, we found the clinical feasibility of this fully noninvasive E/sub max/, estimation method. Therefore, we concluded that E/sub max/ obtained by this methods could be useful for assessment of LV contractility.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128693827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of a virtual instrument for data acquisition and analysis of the phonocardiogram","authors":"Zhenyu Guo, C. Moulder, L. Durand, M. Loew","doi":"10.1109/IEMBS.1998.745939","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.745939","url":null,"abstract":"A medical virtual instrument has been developed to acquire and analyze the phonocardiogram (PCG), the heart sound and murmur signal. This instrument consists of a Pentium 200 computer running Windows95, equipped with LabVIEW software and a plug-in data acquisition board, and a two-channel custom designed bio-signal preamplifier. The bio-signal preamplifier allows the data acquisition board to acquire both the PCG and the electrocardiogram (ECG). LabVIEW software modules have been developed to create virtual instrument's front panels for the following functions: to manage patient information and data files, to capture and display current ECG and heart sound signals while saving or analyzing previous acquired signals, to perform the spectral and time-frequency analysis of the heart sounds and murmurs, and to review the previous recordings. This instrument can be used to display the PCG and to analyze the individual heart sound and murmur for the detection of heart valve diseases. It can also be used to analyze the carotid bruit for the diagnosis of carotid artery stenosis. This study demonstrated that a LabVIEW-based medical virtual instrument provides a low-cost, reliable, and flexible solution for data acquisition and analysis of the PCG and carotid bruit.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128367548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review of biomedical applications of computational intelligence","authors":"Y. Shi, R. Eberhart","doi":"10.1109/IEMBS.1998.747067","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.747067","url":null,"abstract":"Computational intelligence consists of artificial neural networks, evolutionary computation, fuzzy logic systems and the combination of these three components with each other and/or with other traditional approaches. In the past several years, there has been a phenomenal growth in the research and development of technology of computational intelligence. Computational intelligence has found applications in many areas; among them biomedical engineering has evolved into one of the major application areas of computational intelligence. In this paper, we give a brief review of biomedical applications of computational intelligence.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128563059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diamond-like carbon coated medical guidewires","authors":"J. McLaughline, H.-M.W. Hailu","doi":"10.1109/IEMBS.1998.746086","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.746086","url":null,"abstract":"An investigation has been carried out on the possibility of replacing currently employed polymer based coatings on medical guide wires with DLC coatings. The DLC coatings were applied onto the stainless steel guide wires using a radio frequency plasma enhanced chemical vapour deposition (RF-PECVD) chamber. Optical and SEM observations, contact angle measurements, adhesion strength measurement, lubricity test and Raman microscopy, all show that with proper selection of the process parameters of RF-PECVD chamber, a suitable DLC coating can be produced on guide wires.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128987195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Numerical estimation of skull and cortex boundaries from scalp geometry","authors":"H. Haque, T. Musha, M. Nakajima","doi":"10.1109/IEMBS.1998.747040","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.747040","url":null,"abstract":"One of the most sophisticated means of dipole localization is based on a multi-compartment head model in which the inhomogeneity of the electric conductivity of the head is approximated by compartments of uniform conductors. Compartments usually refer to scalp, skull, cerebrospinal fluid (CSF) and brain cortex. The CSF layer in normal subjects is thin and can be neglected in dipole localization to good approximation. The authors aim at constructing the so-called SSB head model in which the CSF layer is neglected. To construct this model 3D MR images or 3D X-ray CT images are necessary. These images, however, are not easy to get, and the authors tried to estimate geometrical shapes of these compartments from a head geometry which is easily measured with a 3D digitizer. The authors have examined the statistical properties of the head structure through 3D MR images of 12 normal subjects, and the estimation error in their method is 1.5 mm for the skull and 2.2 mm for the cortex.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129061729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An uncoupled oscillator model of the Hoffmann reflex","authors":"S. Dorgan, R. Reilly","doi":"10.1109/IEMBS.1998.746151","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.746151","url":null,"abstract":"A simple, new, mathematical model for the Hoffmann reflex is outlined. This model has been developed by considering phase synchronisation of the underlying neuromuscular processes by the electrical stimulation pulse. The novel approach used results in an analytical representation of the muscle's EMG response to a stimulation pulse. With this model, studies to provide insight into, and assessment of, the Hoffmann reflex in response to electrical stimuli delivered to the popliteal fossa at various intensity levels may be carried out. Indices based on the parameters of this model may be developed to provide objective Hoffmann reflex comparisons for the clinical assessment of reflexes in the diagnosis of nerve damage.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129324575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Naguib, E. Albertazzi, F. Cajone, B. Leone, M. S. Lakshmi, G. Sherbet
{"title":"Statistical and blind neural analyses of the expression of the metastasis-associated genes h-mts1 (S100A4) and Nm23 in carcinoma of the breast","authors":"R. Naguib, E. Albertazzi, F. Cajone, B. Leone, M. S. Lakshmi, G. Sherbet","doi":"10.1109/IEMBS.1998.747151","DOIUrl":"https://doi.org/10.1109/IEMBS.1998.747151","url":null,"abstract":"The murine 18A2/mts1 and its human homologue h-mts1 (S100A4) encoding a Ca/sup 2+/-binding protein belonging to the S-100 family have been previously shown to be associated with high invasive and metastatic potential of murine tumours, human tumour cell lines in vitro and of human tumours growth as xenografts. Nm23 is a putative metastasis suppressor gene whose expression has been found to correlate inversely with metastatic potential of some forms of human cancer. In view of the equivocal association of nm23 with the metastatic potential of human cancer, we suggested that the relative expression of h-mts1 and nm23 might reflect tumour progression more accurately than either of them alone. We show here that high h-mts1 expression is associated with metastatic spread to the regional lymph nodes. The expression of nm23 on its own did not show a statistically significant inverse correlation with nodal spread. However, the expression status of the two genes, taken together, correlated strongly with the occurrence of nodal metastases. The clinical data together with the state of expression of steroid receptors and the expression levels of h-mts1 and Nm23 genes were analysed using artificial neural networks for accuracy of prediction of nodal spread of the carcinomas.","PeriodicalId":156581,"journal":{"name":"Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286)","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129736327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}