Japanese Journal of Smooth Muscle Research最新文献_第2页

THE ACTION POTENTIAL OF BOWELS IN RABBITS SUBJECTED TO THE STIMULATION OF THE CORTICAL AREAS 皮质区刺激下家兔肠道的动作电位

Japanese Journal of Smooth Muscle Research Pub Date : 1900-01-01 DOI: 10.1540/jsmr1965.1.155

T. Kashiwagi

{"title":"THE ACTION POTENTIAL OF BOWELS IN RABBITS SUBJECTED TO THE STIMULATION OF THE CORTICAL AREAS","authors":"T. Kashiwagi","doi":"10.1540/jsmr1965.1.155","DOIUrl":"https://doi.org/10.1540/jsmr1965.1.155","url":null,"abstract":"In order to investigate the correlation between the cortical function and the motility of bowels, the responses of the action potentials in bowels to the cutting or stimulation of several cortical areas were observed.Rabbits were anesthetized with urethane. In some of them, the rostral portions of diencephalons were cut and in the others, electrical or chemical (1-glutamate) stimuli were given to the following cortical areas which seem to be closely correlated with the autonomic nervous system; prefrontal area, gyrus cinguli anterior, gyrus cinguli posterior and hypocampus. The action potentials were recorded from the serous membrane sides of duodenum and ileum by means of bipolar metal electrodes. The results obtained were as follows:1. By cutting off the rostral portions of diencephalons, the increase in amplitude of action potential, the appearance of large spikes (200μV or more) and the prolongation of the duration of the burst were observed.2. By stimulation of the prefrontal area, gyrus cinguli anterior and hypocampus, spike potentials increased its amplitude and prolonged its duration. On the other hand, stimulation of gyrus cinguli posterior depressed the action potential.3. After cutting off the vagi at the level of the neck, stimulation of cortical areas was ineffective to produce the remarkable change in action potentials of bowels.","PeriodicalId":156233,"journal":{"name":"Japanese Journal of Smooth Muscle Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130152443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AN EXPERIMENTAL STUDY ON THE MECHANISM OF BILE EXCRETION OF THE CHOLEDOCHODUODENAL JUNCTION 胆总管十二指肠交界处胆汁排泄机制的实验研究

Japanese Journal of Smooth Muscle Research Pub Date : 1900-01-01 DOI: 10.1540/jsmr1965.12.139

M. Nakamoto

{"title":"AN EXPERIMENTAL STUDY ON THE MECHANISM OF BILE EXCRETION OF THE CHOLEDOCHODUODENAL JUNCTION","authors":"M. Nakamoto","doi":"10.1540/jsmr1965.12.139","DOIUrl":"https://doi.org/10.1540/jsmr1965.12.139","url":null,"abstract":"The present study was undertaken to elucidate the mechanism of bile excretion of the choledochoduodenal junction (ch-d junction) in rabbits, especially regarding it's structural and physiological independence from the duodenum.For this purpose muscular anatomy of the ch-d junction and relationship between the electromygoraphic spike potential of this juncture and the intracholedochal pressure were investigated.The results obtained were as follows.1. There were demonstrated proper circular muscle and proper oblique muscle in the ch-d junction, which appeared independent from the duodenal muscle. There existed a muscular sphincter at the terminus of the common bile duct, but it's muscle fibers did not appear continuous with the duodenal muscle fibers.2. The rhythmical changing curve of the intracholedochal pressure was parallel with appearance of the spike potential but had absolutely no correlation with the duodenal one.3. The attitudes of the ch-d junction and the duodenum to the neural control were compared.The spike generation by Neostigmin methylsulfate was equally observed in the ch-d jundtion and the duodenum and the spike inhibition by Hyoscin-Nbutylbromide was also equally observed in both of them, suggesting their innervation was probably common.","PeriodicalId":156233,"journal":{"name":"Japanese Journal of Smooth Muscle Research","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124867366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AN ELECTROMYOGRAPHIC STUDY ON THE CORRELATION BETWEEN GASTRIC AND DUODENAL MOTILITY 胃和十二指肠运动相关性的肌电图研究

Japanese Journal of Smooth Muscle Research Pub Date : 1900-01-01 DOI: 10.1540/JSMR1965.9.123

K. Toyohara

{"title":"AN ELECTROMYOGRAPHIC STUDY ON THE CORRELATION BETWEEN GASTRIC AND DUODENAL MOTILITY","authors":"K. Toyohara","doi":"10.1540/JSMR1965.9.123","DOIUrl":"https://doi.org/10.1540/JSMR1965.9.123","url":null,"abstract":"The purpose of the present electromyographic study in dogs was to elucidate the correlation between gastric and duodenal motility.The action potentials at the pyloric portion of the stomach and the first portion of the duodenum were recorded on, 1) the non-treated control stomach, 2) the transected stomachs to induce hypermotility of the pyloric portion, 3) the vagotomized stomachs following transection to reduce the peristaltic activity, 4) and on the vagotomized stomachs (without transection).The results were as follows:1) The duodenum in 35.7 per cent of the cases showed action potentials in correlation with the gastric action potentials.2) The correlation was increased in the transected stomachs, and slightly decreased in the vagotomized stomachs.3) The gastric action potentials in the transected stomachs showed a tendency of correlation with more distal portion of the duodenum than those in the non-treated control stomachs. This finding was not altered significantly by vagotomy . When the duodenal electrode was placed more distally, the action potentials of the pyloric portion were less frequently correlated.4) The discharge interval was more prolonged and the propagation velocity was larger in the correlated spikes than those of the non-correlated spikes.5) The frequency of the antiperistalsis at the pyloric portion was more decreased in the correlated cases than in the non-correlated ones. Normoperistalsis at the pyloric portion showed a tendency of higher rate of correlation with the duodenum than those of antiperistalsis.6) The duodenal spikes in the correlated cases were more frequent than those in the non-correlated cases.","PeriodicalId":156233,"journal":{"name":"Japanese Journal of Smooth Muscle Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130685200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ELECTROPHYSIOLOGICAL STUDIES ON THE PERISTALTIC PROPAGATION IN THE SIDE-TO-SIDE ANASTOMOSED INTESTINAL LOOPS 侧对侧吻合肠袢蠕动传播的电生理研究

Japanese Journal of Smooth Muscle Research Pub Date : 1900-01-01 DOI: 10.1540/jsmr1965.2.48

T. Tsujimura

{"title":"ELECTROPHYSIOLOGICAL STUDIES ON THE PERISTALTIC PROPAGATION IN THE SIDE-TO-SIDE ANASTOMOSED INTESTINAL LOOPS","authors":"T. Tsujimura","doi":"10.1540/jsmr1965.2.48","DOIUrl":"https://doi.org/10.1540/jsmr1965.2.48","url":null,"abstract":"To study the mode of peristaltic propagation from the oral part to the anal over and across the anastomotic line following side-to-side smallintestinal anastomosis, the action potentials were recorded from the surface of the rabbit's intestine, which was survived by means of a modified Trendelenburg's method.Within one week following the side-to-side anastomosis, spike bursts of varying periods were recorded from electrodes placed above and below the anastomotic line and it was noted that the amplitude was generally low. Within one month after the anastomosis, the spike potentials above the anastomotic line were greater than those of below as in the case of an end-to-end anastomosis. Within two months, however, the action potentials above and below the anastomotic line seem to return to the normal pattern, but the amplitude of spikes recorded from the electrode placed just above or below the anastomotic line was 200μV, and it was lower than those of normal by 30-50μV. In three months after the anastomosis, the patterns of spike bursts were restored from conduction-block to those of the normal, and at this stage it is expected that the effective transport of the intestinal content may take place.","PeriodicalId":156233,"journal":{"name":"Japanese Journal of Smooth Muscle Research","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125509785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ADRENERGIC AND CHOLINERGIC MECHANISMS IN THE HYPOGASTRIC NERVE-SEMINAL VESICLE PREPARATION OF THE GUINEA-PIG 豚鼠胃下神经-精囊制备中的肾上腺素能和胆碱能机制

Japanese Journal of Smooth Muscle Research Pub Date : 1900-01-01 DOI: 10.1540/JSMR1965.9.137

H. Ohkawa

{"title":"ADRENERGIC AND CHOLINERGIC MECHANISMS IN THE HYPOGASTRIC NERVE-SEMINAL VESICLE PREPARATION OF THE GUINEA-PIG","authors":"H. Ohkawa","doi":"10.1540/JSMR1965.9.137","DOIUrl":"https://doi.org/10.1540/JSMR1965.9.137","url":null,"abstract":"Effects of autonomic agents on the responses produced by hypogastric nerve and transmural stimulation of the hypogastric nerve-seminal vesicle preparation of the guinea-pig were examined. Hexamethonium and nicotine blocked the responses to hypogastric stimulation leaving the contractions due to transmural stimulation . TTX and xylocaine blocked both responses. Spontaneous contraction which was observed in 30% of the preparation was not abolished by TTX, hexamethonium, guanethidine and atropine. Acetylcholine, metacholine and noradrenaline elicited or potentiated the spontaneous activity.Adrenaline, noradrenaline, phenylephrine and nialamide enhanced the responses produced by the stimulation of hypogastric and transmural stimulation while guanethidine and phenoxybenzamine reduced the responses. Acetylcholine, metacholine, carbachol and cholinesterase inhibitors increased the responses. Atropine and bevonium inhibited the responses. Required pulse number in the transmural stimulation for producing the contraction was decreased in nialamide, metacholine, carbachol, physostigmine and neostigmine and increased in phenoxybenzamine, guanethidine and atropine.The possibility that adrenergic and cholinergic mechanisms operate independently of each other in the seminal vesicle preparation was discussed.","PeriodicalId":156233,"journal":{"name":"Japanese Journal of Smooth Muscle Research","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116079493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

THE EFFECT OF INGESTED TOPICAL ANESTHETIC ON THE GASTRIC EMPTYING 外用麻醉剂对胃排空的影响

Japanese Journal of Smooth Muscle Research Pub Date : 1900-01-01 DOI: 10.1540/JSMR1965.3.60

K. Hirota, T. Hirashima, F. Tanaka

引用次数: 0

EXPERIMENTAL STUDIES ON THE RELATIONSHIP BETWEEN MYOMETRIAL PROGESTERONE AND UTERINE CONTRACTION 子宫内膜孕酮与子宫收缩关系的实验研究

Japanese Journal of Smooth Muscle Research Pub Date : 1900-01-01 DOI: 10.1540/JSMR1965.2.58

S. Mizota

引用次数: 0

PHYSIOLOGICAL AND PHARMACOLOGICAL STUDIES ON THE MOTILITY OF THE BILE DUCT IN THE CHICKEN 鸡胆管运动的生理药理研究

Japanese Journal of Smooth Muscle Research Pub Date : 1900-01-01 DOI: 10.1540/JSMR1965.10.287

T. Yamasato

{"title":"PHYSIOLOGICAL AND PHARMACOLOGICAL STUDIES ON THE MOTILITY OF THE BILE DUCT IN THE CHICKEN","authors":"T. Yamasato","doi":"10.1540/JSMR1965.10.287","DOIUrl":"https://doi.org/10.1540/JSMR1965.10.287","url":null,"abstract":"1. The muscle of bile ducts does not connect with duodenal muscle and ganglion cells are observed in the submucosa and muscle layers. There is no special sphincter muscle in the orifice of the duct.2. The bile is transproted by peristalses from hepatic side to the duodenum in vivo.3. In the isolated bile duct (hepato-duodenal duct), raising the intraluminal pressure induced rhythmic contraction or increased spontaneous contraction.4. Adernaline, noradrenaline and phenylephrine as well as acetylcholine increased the contraction, while isoprenaline inhibited the spontaneous contraction in number. After treatment with pindroll, adrenaline strengthened the contraction, while after treatment with phenoxybenzamine the excitatory effect responsbile to adrenaline was abolished.5. The excitatory effect of nicotine was abolished after tetrodotoxin, but the excitatory effect induced by raising intraluminal pressure was not abolished with tetrodotoxin. However, after treatment of hexamethonium bromide, nicotine or atropine, the excitatory effect of raising intraluminal pressure was slightly reduced. It is supposed that the contraction induced by raising intraluminal pressure after treat-ment of these agents is myogenic in origin.","PeriodicalId":156233,"journal":{"name":"Japanese Journal of Smooth Muscle Research","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122271244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

STUDIES ON THE DEVELOPMENT OF GASTRIC ULCER RELATING TO THE SMOOTH MUSCLE OF STOMACH BY ELECTRO-GASTROGRAPHY 胃电图研究与胃平滑肌有关的胃溃疡的发生

Japanese Journal of Smooth Muscle Research Pub Date : 1900-01-01 DOI: 10.1540/JSMR1965.1.21

M. Oi, Yoshiki Tanaka, Kan Yoshida, K. Yanagisawa, T. Yamanaka, Yoshiyuki Sato, T. Koga, K. Yoshikawa

引用次数: 0

ELECTROMYOGRAPHIC STUDY OF THE CANINE STOMACH 犬胃的肌电图研究

Japanese Journal of Smooth Muscle Research Pub Date : 1900-01-01 DOI: 10.1540/JSMR1965.15.267

Y. Shimasaki

{"title":"ELECTROMYOGRAPHIC STUDY OF THE CANINE STOMACH","authors":"Y. Shimasaki","doi":"10.1540/JSMR1965.15.267","DOIUrl":"https://doi.org/10.1540/JSMR1965.15.267","url":null,"abstract":"In order to clarify the propagation mechanism of canine gastric electrical activity, the stomach was transected and reanastomosed at the middle antrum in 3 dogs and at the distal corpus in 3 dogs.Two bipolar electrodes were implanted in the pre- and postanastomosis stomach. Electromyographic recordings were performed intermittently for 8 to 13 weeks in fasting and after feeding. In one of the 6 dogs, 11 weeks after the initial surgery, one half of the anterior muscle wall of the greater curvature side was reapproximated.In fasting, the BER interval in the preanastomosis remained unchanged, but that in the postanastomosis became prolonged. After feeding, the BER interval in the postanastomosis was shortened and showed an advancement to close to that in the preanastomosis. 3 weeks after reapproximation of partial muscle wall, the BER interval in the postanastomosis recovered to the same BER interval as in the preanastomosis in fasting and after feeding stages. Dysrhythmia in the postanastomosis was of temporal occurrance.These results suggest that an inherent automatism in the gastric wall plays a role in the recovery of the BER interval and close muscle approximation is essential for propagation of gastric electrical activities.","PeriodicalId":156233,"journal":{"name":"Japanese Journal of Smooth Muscle Research","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124064860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1