Journal of dermatological case reports最新文献_第3页

The diagnostic value of trichoscopy in systemic sclerosis. 毛镜检查在系统性硬化症中的诊断价值。

Journal of dermatological case reports Pub Date : 2016-11-13 DOI: 10.3315/JDCR.2016.1225

Małgorzata Kwiatkowska, A. Rakowska, I. Walecka, L. Rudnicka

{"title":"The diagnostic value of trichoscopy in systemic sclerosis.","authors":"Małgorzata Kwiatkowska, A. Rakowska, I. Walecka, L. Rudnicka","doi":"10.3315/JDCR.2016.1225","DOIUrl":"https://doi.org/10.3315/JDCR.2016.1225","url":null,"abstract":"BACKGROUND/OBJECTIVES\u0000Systemic sclerosis is a connective tissue disease, which is characterized by fibrosis of the skin and internal organs, presence of specific antibodies and vascular involvement. Capillaroscopy is a useful method for the diagnosis and follow-up of patients with systemic sclerosis. Trichoscopy is a rapid, non-invasive technique, which has become a standard procedure in differential diagnosis of scalp and hair diseases. The aim of this study was to assess whether trichoscopy may be applied in imaging microvessels in patients with systemic sclerosis.\u0000\u0000\u0000METHODS\u0000The study included 17 patients with systemic sclerosis, and 31 healthy patients. In every patient 10 trichoscopy images were taken with Fotofinder II.\u0000\u0000\u0000RESULTS\u0000In patients with systemic sclerosis trichoscopy of the frontal scalp area revealed polymorphic microvessels in 64,7% of patients, spider vessels (76,4%), capillary loops (52,9%), arborising vessels (41,1%) and avascular areas (35,2%). In healthy individuals these features were observed in polymorphic microvessels 6,4% of patients, spider vessels 6,4%, capillary loops 100%, arborising vessels 16,1%, avascular areas 9,6%, respectively.\u0000\u0000\u0000CONCLUSIONS\u0000In conclusion, the presence of polymorphic vessels in frontal area in trichoscopy is characteristic for systemic sclerosis.","PeriodicalId":15601,"journal":{"name":"Journal of dermatological case reports","volume":"46 1","pages":"21-25"},"PeriodicalIF":0.0,"publicationDate":"2016-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80573780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Erythroderma. A clinical and etiological study of 103 patients. 红皮病。103例患者的临床及病因学研究。

Journal of dermatological case reports Pub Date : 2016-03-31 DOI: 10.3315/jdcr.2016.1222

Artur César, Maria Cruz, Alberto Mota, Filomena Azevedo

{"title":"Erythroderma. A clinical and etiological study of 103 patients.","authors":"Artur César, Maria Cruz, Alberto Mota, Filomena Azevedo","doi":"10.3315/jdcr.2016.1222","DOIUrl":"https://doi.org/10.3315/jdcr.2016.1222","url":null,"abstract":"Background: Erythroderma is an uncommon and severe dermatological manifestation of a variety of diseases. It is commonly challenging to find the underlying cause.Objective: The aim of this study was to analyze the causes of the disease in patients with erythroderma.Patients and methods: Data including the clinical symptoms, laboratory examinations, histopathology and follow-up information were collected from patients with erythroderma admitted to our department between 2000 and 2010.Results: One-hundred and three patients diagnosed with erythroderma were identified during this period (11.9% of all hospitalized patients; hospital incidence = 9.4 cases/year). The mean age of onset was 54.4 years (range: 17-89 years) with a male:female ratio of 1.5:1. The most frequent cause of erythroderma was exacerbation of preexisting dermatoses (65.0%), including psoriasis (44.7%) and eczema (16.5%). Drugs (18.4%) and cutaneous T-cell lymphomas (11.7%) induced most of the remaining cases. No cause could be identified in four cases (3.9%). Apart from erythema and scaling, that were present in all patients, clinical findings were dominated by pruritus (97.1%), followed by edema (56.3%), fever (54.4%), palmoplantar keratoderma (50.5%), nail changes (42.7%), liver or spleen enlargement (41.7%) and lymphadenopathy (40.8%).Conclusions: Although numerous clinical features and laboratory values were abnormal, most findings were non-specific. The skin biopsy yielded a positive clinical correlation in most cases. Our study had a high percentage of erythroderma secondary to preexisting skin disease and a relatively low percentage of idiopathic erythroderma.","PeriodicalId":15601,"journal":{"name":"Journal of dermatological case reports","volume":"10 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2016-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3315/jdcr.2016.1222","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34495314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 57

Stevens-Johnson syndrome in a patient with rheumatoid arthritis during long-term etanercept therapy. 类风湿关节炎患者长期依那西普治疗期间的史蒂文斯-约翰逊综合征。

Journal of dermatological case reports Pub Date : 2016-03-31 DOI: 10.3315/jdcr.2016.1224

Agnieszka Owczarczyk-Saczonek, Natalia Zdanowska, Aleksandra Znajewska-Pander, Waldemar Placek

{"title":"Stevens-Johnson syndrome in a patient with rheumatoid arthritis during long-term etanercept therapy.","authors":"Agnieszka Owczarczyk-Saczonek, Natalia Zdanowska, Aleksandra Znajewska-Pander, Waldemar Placek","doi":"10.3315/jdcr.2016.1224","DOIUrl":"https://doi.org/10.3315/jdcr.2016.1224","url":null,"abstract":"Background: Etanercept and other anti-TNF-alpha agents have been indicated as a therapeutic option in severe drug reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis. Etanercept has been shown to quickly reduce the detachment of the epidermis and shorten healing time. Cases of etanercept-induced severe adverse drug reactions were also described.Main observations: A 27-year-old woman with a 4-year history of etanercept and sulfasalazine treatment for rheumatoid arthritis was admitted with Stevens-Johnson syndrome. The patient received one dose of an OTC drug containing acetaminophen, phenylephrine and pheniramine two days prior to developing fist mucocutaneous symptoms. The most probable causative agent was paracetamol. Throughout the successful routine therapy of Stevens-Johnson syndrome etanercept therapy was continued. Sulfosalazin administration was stopped and administered again after recovery with no recurrence of the skin and mucosal symptoms.Conclusions: This case indicates that there is no justification for discontinuation of long-term anti-TNF-alpha treatment in patients who develop Stevens- Johnson syndrome / toxic epidermal necrolysis.","PeriodicalId":15601,"journal":{"name":"Journal of dermatological case reports","volume":"10 1","pages":"14-6"},"PeriodicalIF":0.0,"publicationDate":"2016-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3315/jdcr.2016.1224","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34495316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Photoletter to the editor: Dermoscopy as a diagnostic aid for pruritic folliculitis of pregnancy. 给编辑的信:皮肤镜检查作为妊娠瘙痒性毛囊炎的诊断辅助。

Journal of dermatological case reports Pub Date : 2016-03-31 DOI: 10.3315/jdcr.2016.1227

Enzo Errichetti, Giuseppe Stinco

引用次数: 1

Photoletter to the editor: Postradiation sarcoma. 给编辑的照相信:放射后肉瘤。

Journal of dermatological case reports Pub Date : 2016-03-31 DOI: 10.3315/jdcr.2016.1228

Cristina Garrido-Colmenero, Ignacio Valenzuela-Salas, Gonzalo Blasco-Morente, José Aneiros-Fernández, Jesús Tercedor-Sánchez

引用次数: 2

Sporadic and familial cases of aquagenic keratoderma. 水源性角化病的散发和家族性病例。

Journal of dermatological case reports Pub Date : 2016-03-31 DOI: 10.3315/jdcr.2016.1223

Hülya Nazik, Selçuk Nazik, Feride Gül Çoban, Betül Demir

{"title":"Sporadic and familial cases of aquagenic keratoderma.","authors":"Hülya Nazik, Selçuk Nazik, Feride Gül Çoban, Betül Demir","doi":"10.3315/jdcr.2016.1223","DOIUrl":"https://doi.org/10.3315/jdcr.2016.1223","url":null,"abstract":"Background: Aquagenic keratoderma is a dermatosis characterized by transient whitish and transluscent hyperwrinkling after water exposure. The aim of the current report was to present a sporadic and familial cases of aquagenic keratoderma.Observation: Sporadic Case: A 38-year-old female patient presented with eruption in the right hand after exposure to water. The patient was placed on systemic acitretin therapy with the diagnosis of idiopathic acquired aquagenic keratoderma. No recurrence occurred during a 6-month follow-up period. Familial Cases: A 55-year-old male patient, who was engaged in fishery, presented to the outpatient clinics of the department of dermatology due to whitish vesicles in the palms of both hands. It was realized that the father, sister, and brother of the patient had similar complaints. The cases were thought to have familial aquagenic keratoderma; however acitretin therapy could not be initiated due to elevated alanine aminotransferase and triglyceride levels. Topical application of salicylic acid 10% and 10% urea containing lotions was effective but did not prevent recurrence.Conclusion: Systemic acitretin may be an effective agent in the treatment of aquagenic keratoderma, and topical application of 10% salicylic acid and 10% urea-containing lotion did not prevent recurrence.","PeriodicalId":15601,"journal":{"name":"Journal of dermatological case reports","volume":"10 1","pages":"10-3"},"PeriodicalIF":0.0,"publicationDate":"2016-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3315/jdcr.2016.1223","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34495315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Ichthyosis linearis circumflexa in a child. Response to narrowband UVB therapy. 线型鱼鳞病是儿童的环状鱼鳞病。对窄带UVB治疗的反应。

Journal of dermatological case reports Pub Date : 2015-12-31 DOI: 10.3315/jdcr.2015.1214

R. Singer, M. Copur, Ece Yüksel, E. Kocatürk, S. Erhan

引用次数: 10

Non-invasive diagnostic techniques in the diagnosis of squamous cell carcinoma. 无创诊断技术在鳞状细胞癌诊断中的应用。

Journal of dermatological case reports Pub Date : 2015-12-31 DOI: 10.3315/jdcr.2015.1221

O. Warszawik-Hendzel, M. Olszewska, M. Maj, A. Rakowska, J. Czuwara, L. Rudnicka

{"title":"Non-invasive diagnostic techniques in the diagnosis of squamous cell carcinoma.","authors":"O. Warszawik-Hendzel, M. Olszewska, M. Maj, A. Rakowska, J. Czuwara, L. Rudnicka","doi":"10.3315/jdcr.2015.1221","DOIUrl":"https://doi.org/10.3315/jdcr.2015.1221","url":null,"abstract":"Squamous cell carcinoma is the second most common cutaneous malignancy after basal cell carcinoma. Although the gold standard of diagnosis for squamous cell carcinoma is biopsy followed by histopathology evaluation, optical non-invasive diagnostic tools have obtained increased attention. Dermoscopy has become one of the basic diagnostic methods in clinical practice. The most common dermoscopic features of squamous cell carcinoma include clustered vascular pattern, glomerular vessels and hyperkeratosis. Under reflectance confocal microscopy, squamous cell carcinoma shows an atypical honeycomb or disarranged pattern of the spinous-granular layer of the epidermis, round nucleated bright cells in the epidermis and round vessels in the dermis. High frequency ultrasound and optical coherence tomography may be helpful in predominantly in pre-surgical evaluation of tumor size. Emerging non-invasive or minimal invasive techniques with possible application in the diagnosis of squamous cell carcinoma of the skin, lip, oral mucosa, vulva or other tissues include high-definition optical coherence tomography, in vivo multiphoton tomography, direct oral microscopy, electrical impedance spectroscopy, fluorescence spectroscopy, Raman spectroscopy, elastic scattering spectroscopy, differential path-length spectroscopy, nuclear magnetic resonance spectroscopy, and angle-resolved low coherence interferometry.","PeriodicalId":15601,"journal":{"name":"Journal of dermatological case reports","volume":"38 1","pages":"89-97"},"PeriodicalIF":0.0,"publicationDate":"2015-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87451437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 54

Photoletter to the editor: Calcinosis cutis in a burn scar. 给编辑的照片:烧伤疤痕的皮肤钙质沉着症。

Journal of dermatological case reports Pub Date : 2015-12-31 DOI: 10.3315/jdcr.2015.1219

A. Rosmaninho, S. Carvalho, I. Lobo

引用次数: 5

A rapidly growing giant cutaneous horn on the chest. 胸部迅速生长的巨大的皮角。

Journal of dermatological case reports Pub Date : 2015-12-31 DOI: 10.3315/jdcr.2015.1217

L. Soriano, M. Piansay‐Soriano

{"title":"A rapidly growing giant cutaneous horn on the chest.","authors":"L. Soriano, M. Piansay‐Soriano","doi":"10.3315/jdcr.2015.1217","DOIUrl":"https://doi.org/10.3315/jdcr.2015.1217","url":null,"abstract":"BACKGROUND\u0000A giant cutaneous horn (GCH) is a morphologic description of conical lesion with a dense, hyperkeratotic protrusion of more than 1 cm in height that resembles an animal horn but without its bony core. These can occur in association with benign, premalignant or malignant cutaneous diseases which can be determined by excision and histopathologic review of the base. A PubMed search (performed June 2015) revealed 54 cases of giant cutaneous horns in world literature. The most common site affected was the scalp followed by lip and leg. The commonest histological diagnosis found was squamous cell carcinoma followed by verruca vulgaris and trichilemmal horns.\u0000\u0000\u0000MAIN OBSERVATION\u0000We present an 85-year-old Filipino female with a one year history of a rapidly growing skin lesion on her upper chest. This was excised fully and histological review of the base demonstrated a keratoacanthoma.\u0000\u0000\u0000CONCLUSIONS\u0000This is the first known occurrence of a giant cutaneous horn on the chest. While giant cutaneous horns are more commonly associated with malignant lesions, differential diagnosis includes benign lesions such as keratoacanthomas. This differential can be considered in a rapidly growing lesion. Excision and histopathologic review of the base of a cutaneous horn are essential to guide potential further therapy.","PeriodicalId":15601,"journal":{"name":"Journal of dermatological case reports","volume":"16 1","pages":"113-5"},"PeriodicalIF":0.0,"publicationDate":"2015-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86573825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8