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The Neural Symphony in the Periodontium: Health, Inflammation, and Regeneration 牙周组织中的神经交响曲：健康、炎症和再生
IF 7.6 1区 医学
Journal of Dental Research Pub Date : 2026-10-12 DOI: 10.1177/00220345261479223
C. Zhan,M. Huang,Q. Dai,L. Jin,Y. Lin
{"title":"The Neural Symphony in the Periodontium: Health, Inflammation, and Regeneration","authors":"C. Zhan,M. Huang,Q. Dai,L. Jin,Y. Lin","doi":"10.1177/00220345261479223","DOIUrl":"https://doi.org/10.1177/00220345261479223","url":null,"abstract":"","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"49 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149152661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stereo Electron Microscopy of Enamel Crystallites 釉质晶体的立体电子显微镜研究
IF 7.6 1区 医学
Journal of Dental Research Pub Date : 2026-10-01 DOI: 10.1177/0022034582061special07
H. Warshawsky, A. Nanci
{"title":"Stereo Electron Microscopy of Enamel Crystallites","authors":"H. Warshawsky, A. Nanci","doi":"10.1177/0022034582061special07","DOIUrl":"https://doi.org/10.1177/0022034582061special07","url":null,"abstract":"<jats:italic toggle=\"yes\">Stereo microscopy was used to examine enamel crystallites in routine thin sections of rat and Chinese hamster incisors. Freeze-fracture replicas were also made of rat incisor enamel. These studies revealed that enamel crystallites are thin, flat, twisting ribbons of unmeasurable length and uniform width. Images previously interpreted as hexagonal crystallites are due to perspective distortion caused by oblique views along cut segments of these flattened ribbons exaggerated by curling, which occurs at the cut crystallite ends. Images of central crystallite dissolution, resulting from beam sublimation, are due to oblique views of hole-pitted crystallite surfaces. Finally, it was concluded that previous measurements made from two-dimensional images of crystallites in electron micrographs are not reliable.</jats:italic>","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"196 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of Rat Incisor Ameloblasts with Maturation Cycles as Displayed on Enamel Surface with EDTA EDTA在牙釉质表面显示大鼠切牙成釉细胞与成熟周期的相关性
IF 7.6 1区 医学
Journal of Dental Research Pub Date : 2026-10-01 DOI: 10.1177/0022034582061special14
E.J. Reith, A. Boyde, M.I. Schmid
{"title":"Correlation of Rat Incisor Ameloblasts with Maturation Cycles as Displayed on Enamel Surface with EDTA","authors":"E.J. Reith, A. Boyde, M.I. Schmid","doi":"10.1177/0022034582061special14","DOIUrl":"https://doi.org/10.1177/0022034582061special14","url":null,"abstract":"","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"12 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-method Analysis of Calcium Localization in the Secretory Ameloblast 分泌性成釉细胞钙定位的多方法分析
IF 7.6 1区 医学
Journal of Dental Research Pub Date : 2026-10-01 DOI: 10.1177/0022034582061special13
D. R. Eisenmann, S. Ashrafi, A. E. Zaki
{"title":"Multi-method Analysis of Calcium Localization in the Secretory Ameloblast","authors":"D. R. Eisenmann, S. Ashrafi, A. E. Zaki","doi":"10.1177/0022034582061special13","DOIUrl":"https://doi.org/10.1177/0022034582061special13","url":null,"abstract":"<jats:italic toggle=\"yes\">X-ray micro-analysis and electron energy loss analysis were used to confirm cytochemical localization by potassium pyro-antimonate of calcium in secretory ameloblasts. Neither intercellular calcium concentration between ameloblasts nor over-all calcium levels of the enamel organ were lowered during a period of inhibition of enamel mineralization by injected fluoride. Calcium concentrations in mitochondria and secretory granules were reduced.</jats:italic>","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"167 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of Enamel in Human Fetal Teeth 人胎儿牙釉质的发育
IF 7.6 1区 医学
Journal of Dental Research Pub Date : 2026-10-01 DOI: 10.1177/0022034582061special11
D. Deutsch, E. Pe'er
{"title":"Development of Enamel in Human Fetal Teeth","authors":"D. Deutsch, E. Pe'er","doi":"10.1177/0022034582061special11","DOIUrl":"https://doi.org/10.1177/0022034582061special11","url":null,"abstract":"<jats:italic toggle=\"yes\">The present study concerns enamel development in human fetal teeth. Chemical analysis and the appearance of developing enamel from maxillary and mandibular central and lateral incisors of human fetuses aged from five to nine mo distinguished two main stages during this period of development. The first stage corresponded to the production of forming enamel, which was soft, translucent, and partially mineralized, and the second to the maturation or secondary mineralization of enamel. The enamel at this stage appeared opaque when dried. The transition of forming enamel to maturing enamel was accompanied by a decrease in protein concen-tration, a distinct change in amino-acid composition, and a rise in the concentration of calcium and phosphate. Ultraviolet and chloro-naphthalene imbibition studies revealed that the third and final stage in enamel development, the mature hard enamel, was generally absent, but was found in a very small percentage of maxillary and mandibular central incisors from nine- and ten-month-old fetuses, at the incisal tip. In both maxillary and mandibular canine teeth, only the forming stage in enamel development was observed during the fetal period. Further studies relating the length of each zone in enamel to fetal age provided information relative to the timing and rate of enamel development in each tooth.</jats:italic>","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"32 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enamel Proteins: From Secretion to Maturation 釉质蛋白：从分泌到成熟
IF 7.6 1区 医学
Journal of Dental Research Pub Date : 2026-10-01 DOI: 10.1177/0022034582061special05
C. Robinson, J. Kirkham, H.D. Briggs, P.J. Atkinson
{"title":"Enamel Proteins: From Secretion to Maturation","authors":"C. Robinson, J. Kirkham, H.D. Briggs, P.J. Atkinson","doi":"10.1177/0022034582061special05","DOIUrl":"https://doi.org/10.1177/0022034582061special05","url":null,"abstract":"","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"53 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrastructural Changes of Secreting Rat-incisor Ameloblasts following Administration of Vincristine and Vinblastine 长春新碱和长春新碱对大鼠门牙成釉细胞超微结构的影响
IF 7.6 1区 医学
Journal of Dental Research Pub Date : 2026-10-01 DOI: 10.1177/0022034582061special02
S. Takuma, T. Sawada, T. Yanagisawa
{"title":"Ultrastructural Changes of Secreting Rat-incisor Ameloblasts following Administration of Vincristine and Vinblastine","authors":"S. Takuma, T. Sawada, T. Yanagisawa","doi":"10.1177/0022034582061special02","DOIUrl":"https://doi.org/10.1177/0022034582061special02","url":null,"abstract":"<jats:italic toggle=\"yes\">Ultrastructural changes of secreting rat-incisor ameloblasts after administration of vincristine and vinblastine were observed. Polarity of nuclei and cytoplasmic organellae was remarkably disturbed; consequently, the regular secreting orientation of cellular products was altered greatly, leading to heterotopic deposition of large amounts of enamel matrix.</jats:italic>","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"32 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanisms by which the Enamel Organ Controls Calcium Entry into Developing Enamel 釉质器官控制钙进入釉质发育的机制
IF 7.6 1区 医学
Journal of Dental Research Pub Date : 2026-10-01 DOI: 10.1177/0022034582061special15
M.A. Crenshaw, Y. Takano
{"title":"Mechanisms by which the Enamel Organ Controls Calcium Entry into Developing Enamel","authors":"M.A. Crenshaw, Y. Takano","doi":"10.1177/0022034582061special15","DOIUrl":"https://doi.org/10.1177/0022034582061special15","url":null,"abstract":"<jats:italic toggle=\"yes\">The secretory ameloblasts and the bands of ruffle-ended maturation ameloblasts function as tight epithelia that control calcium entry into developing enamel by cellular membrane transport processes. In secretory ameloblasts, this transport process appears to be a Ca-activated ATPase distributed over the entire membrane surface. Because about 80% of the plasma membrane surface is proximal to the intercellular tight junctions, the pumping action is directed away from enamel so that calcium entry into secretory enamel is very limited.</jats:italic> <jats:italic toggle=\"yes\"> The majority of the plasma membrane surface area is distal to the intercellular tight junctions in the bands of ruffle-ended ameloblasts. Therefore, the cellular membrane transport process for calcium is directed toward the enamel. It is postulated that this process is a Na <jats:sup>+</jats:sup> ⋅Ca <jats:sup>2+</jats:sup> exchange. </jats:italic> <jats:italic toggle=\"yes\"> Calcium entry into enamel overlaid by the bands of smooth-ended maturation ameloblasts seems less important. <jats:sup>45</jats:sup> Ca auto-radiographic studies show only a moderate incorporation of the tracer into enamel overlaid by these bands, which account for only about 20% of the maturation enamel surface area in the rat incisor. </jats:italic>","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"481 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progressive Mineralization Pattern of Developing Enamel during the Maturation Stage 成熟阶段牙釉质的递进矿化模式
IF 7.6 1区 医学
Journal of Dental Research Pub Date : 2026-10-01 DOI: 10.1177/0022034582061special10
S. Suga
{"title":"Progressive Mineralization Pattern of Developing Enamel during the Maturation Stage","authors":"S. Suga","doi":"10.1177/0022034582061special10","DOIUrl":"https://doi.org/10.1177/0022034582061special10","url":null,"abstract":"<jats:italic toggle=\"yes\">The maturation stage of developing enamel may be divided into three substages: First, a secondary mineralization increase appears from the surface toward the deeper layer; then, a tertiary mineralization increase takes place from the deeper layer toward the surface; and finally, the narrow subsurface layer mineralizes heavily and attains the highest degree of mineralization of all layers.</jats:italic>","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"53 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comments on the Porosity of Human Tooth Enamel 关于人类牙釉质孔隙度的评述
IF 7.6 1区 医学
Journal of Dental Research Pub Date : 2026-10-01 DOI: 10.1177/0022034582061special09
R. W. Fearnhead, K. Kawasaki, K. Inouet
{"title":"Comments on the Porosity of Human Tooth Enamel","authors":"R. W. Fearnhead, K. Kawasaki, K. Inouet","doi":"10.1177/0022034582061special09","DOIUrl":"https://doi.org/10.1177/0022034582061special09","url":null,"abstract":"<jats:italic toggle=\"yes\">The porous nature of surface and sub-surface enamel undergoing the final stages of maturation has been observed on unerupted, partly-erupted, and fully-erupted human teeth, using polarized light microscopy, microradiography, and scanning electron microscopy. Maturation deficiency of developmental origin can be distinguished from early carious lesions with polarized light by the absence of a well-circumscribed \"dark\" zone.</jats:italic>","PeriodicalId":15596,"journal":{"name":"Journal of Dental Research","volume":"23 1","pages":""},"PeriodicalIF":7.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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