Kolli Harika, V. Badikillaya, Sivaprabodh Vuddandi, Kalyan K. Hukumathirao, Percy Jammalamadaka
{"title":"Early clinical exposure on Gout for first year medical undergraduates at a tertiary care teaching hospital in South India- A mixed methods study","authors":"Kolli Harika, V. Badikillaya, Sivaprabodh Vuddandi, Kalyan K. Hukumathirao, Percy Jammalamadaka","doi":"10.4103/jdrntruhs.jdrntruhs_49_22","DOIUrl":"https://doi.org/10.4103/jdrntruhs.jdrntruhs_49_22","url":null,"abstract":"Background: The department of biochemistry at a tertiary care teaching hospital had the first offline early clinical exposure (ECE) on gout in October 2021 in the aftermath of COVID 19. This paper is based on our experiences of conducting ECE according to Competency Based Medical Education in the classroom. Aim: To share our experiences of conducting ECE in a faculty constrained setting. Methods: This was a mixed methods study. A total of 187 students out of 200 were present on the day of ECE. A pre- and post-test of ten questions on nucleotide metabolism was administered to the students. The subject for the module was a 48-year-old farmer suffering from gout who kindly consented to be a part of the program which was coordinated with the orthopedics department. After the module, the students wrote their reflections in the logbook and also gave their written feedback. Results: The reflections revealed that they felt motivated to study the biochemical aspects of the disease as this helped them understand the clinical picture. The feedback revealed that they preferred having more such ECE sessions. The mean post-test and pre-test scores were 7.7 and 5.6, respectively. Conclusion: ECE improved the students' learning and motivated them to study the subject. The reflection and feedback by students demonstrate that the students were enthusiastic and motivated to participate in the ECE. The objective in disseminating our findings is to share the ECE experiences so that we can standardize the competencies and objectives of common clinical conditions in biochemistry.","PeriodicalId":15571,"journal":{"name":"Journal of Dr. NTR University of Health Sciences","volume":"5 1","pages":"301 - 306"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75657225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Uropathogens and their antibiotic susceptibility pattern in rural population: A cross-sectional observative study","authors":"M. Mekala, M. Pradeep, V. Kakumanu","doi":"10.4103/jdrntruhs.jdrntruhs_104_22","DOIUrl":"https://doi.org/10.4103/jdrntruhs.jdrntruhs_104_22","url":null,"abstract":"Introduction: Urinary tract infections (UTIs) are one of the widespread human microbial disorders affecting all the age groups, which may involve the whole part of the urinary tract from the urethra to kidneys and are associated with a significant burden of mortality and morbidity. Although various microorganisms, including viruses, fungi, and parasites, are responsible for UTIs, bacteria are the leading cause. The prevalence of uropathogens in cases of UTI varies according to demographic features, community or hospital-based and also due to the use of different antibiotics in the community and hospital settings. Aim of the Study: To determine the prevalence of uropathogens and their antibiotic susceptibility pattern in rural populations. Study Design: This is a cross-sectional observational study conducted at the Department of Microbiology, Dr.PSIMS & RF, Chinaoutapalli, Andhra Pradesh. Materials and Methods: A total of 1378 clean-catch midstream urine samples from clinically suspected cases of UTI which were received from outpatient and inpatient set-up of various clinical departments were processed according to standard protocol and guidelines and the isolated pathogens were subjected to antibiotic susceptibility testing by Kirby-Bauer disc diffusion method and interpreted according to CLSI guidelines. Results: In the present study, the prevalence of UTI is 29.53%, where Escherichia coli is the predominant isolate (56.06), followed by Klebsiella spp (16.95%) and among Gram-positives, Enterococcus faecalis is the predominant isolate (10.81%) followed by Staphylococcus aureus (2.70%). Conclusion: As the prevalence of bacterial uropathogens as well as their antibiotic sensitivity pattern varies in different geographical locations and time to time it is important that the diagnosis of UTI is not only dependent on the clinical signs and symptoms, it should be correlated with the positive urine culture and the antibiotic susceptibility pattern of the uropathogen isolated. Without having knowledge about the prevalence of uropathogens in that particular area and their susceptibility pattern, starting empirical antibiotic therapy will not only prolong the disease and lead to complications in the patients, and a negative consequence will also be added in the form of the development of multidrug resistance (MDR).","PeriodicalId":15571,"journal":{"name":"Journal of Dr. NTR University of Health Sciences","volume":"1 1","pages":"356 - 361"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76183377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Sangeetha, K. Charan, B. Santana, M. Kumari, P. Murali, G. Priya
{"title":"Drugs banned in other countries, still prevailing in India, a vital matter of concern—A narrative review","authors":"R. Sangeetha, K. Charan, B. Santana, M. Kumari, P. Murali, G. Priya","doi":"10.4103/jdrntruhs.jdrntruhs_134_22","DOIUrl":"https://doi.org/10.4103/jdrntruhs.jdrntruhs_134_22","url":null,"abstract":"Drugs and their formulations are mainly used in the prevention and treatment of disease or disorders; out of such drugs, only some are considered to be essential and life-saving, whereas others remain substitutes for each other. When some serious adverse effect is faced by a general population on the consumption of the particular drug, the adverse side effects are monitored through pharmacovigilance; when the hazard overshadows the benefit, then the drug is proposed for a ban in the country. Some drugs potentiate the adverse effect only when it is in combination with another drug, which is considered to be irrational; in such situations, the Fixed Dose Combinations FDC is banned but not the single drug. Banned drugs are still available in India, and this might be due to the lack of awareness and knowledge among clinicians and the persistence of loopholes in Indian laws governing the approval and manufacture of drugs. The government needs to enforce laws and increase drug information centers and ensure their proper functioning, from where the update on each drug will be provided to doctors and the general population.","PeriodicalId":15571,"journal":{"name":"Journal of Dr. NTR University of Health Sciences","volume":"42 1","pages":"259 - 264"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90950317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative study between Guy's stone score, S.T.O.N.E nephrolithometry and Clinical Research Office of the Endourological Society (CROES) nephrolithometric nomogram in predicting stone-free rates in patients undergoing percutaneous nephrolithotomy: A prospective analysis","authors":"S. Shahab, E. Galeti, M. Bharali","doi":"10.4103/jdrntruhs.jdrntruhs_42_22","DOIUrl":"https://doi.org/10.4103/jdrntruhs.jdrntruhs_42_22","url":null,"abstract":"Background: Several scoring systems have recently emerged to predict stone-free rates (SFRs) after percutaneous nephrolithotomy (PCNL). We aimed to compare the most commonly used scoring systems (Guy's stone score, STONE nephrolithometry and Clinical Research Office of the Endourological Society (CROES) nomogram) and assess their predictive accuracy for stone-free rates (SFRs). We also evaluated these scoring systems in their ability to predict perioperative complications, operative time (OT), length of hospital stay (LOH) and postoperative fall in haemoglobin. Methods: We prospectively evaluated 50 consecutive patients with renal calculi who underwent PCNL at our institute for two years. Preoperative CT was done in all the patients. We applied GSS, STONE nephrolithometry and CROES nomogram in all patients. The association of these scoring systems with SFR, perioperative complications, OT, LOH and fall in haemoglobin was evaluated. Results: The overall SFR in our study was 94%. The mean score of GSS, STONE and CROES was 1.66 ± 0.71, 7.08 ± 1.77 and 86.9 ± 4.35. GSS (AUC – 0.86) and S.T.O.N.E nephrolithometry (AUC – 0.837) score effectively predicted SFR, unlike CROES nomogram (AUC – 0.223). The overall complication rate was 54%. GSS (AUC – 0.643) and S.T.O.N.E nephrolithometry (AUC – 0.628) score effectively predicted post-operative complications, unlike CROES nomogram (AUC – 0.308). All three scoring systems (GSS, STONE and CROES) significantly correlated with OT (P < 0.01). None of the scoring systems correlated with LOH. GSS and CROES nomogram showed a weak correlation with fall in Hb. Conclusion: GSS and STONE nephrolithometry effectively predicted SFR and perioperative complication, unlike the CROES nomogram. All scoring systems correlated with OT. Scoring systems did not correlate with LOH. GSS and CROES nomogram weakly correlated with fall in haemoglobin.","PeriodicalId":15571,"journal":{"name":"Journal of Dr. NTR University of Health Sciences","volume":"1 1","pages":"336 - 343"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83036778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Veerraju, J. Prabha Kona, G. Babu, Devarakonda Sesi, K. Babji
{"title":"Students attitude towards newer methods of medical education teaching in CBME phase-1 (Anatomy) in a Government Medical College, Andhra Pradesh","authors":"A. Veerraju, J. Prabha Kona, G. Babu, Devarakonda Sesi, K. Babji","doi":"10.4103/jdrntruhs.jdrntruhs_163_21","DOIUrl":"https://doi.org/10.4103/jdrntruhs.jdrntruhs_163_21","url":null,"abstract":"Background: In the era of new competency based medical education (CBME) curriculum, teaching and learning anatomy is considered as most challenging part both for students and teachers. Objectives: The aim of this study was (1) to assess the attitude of students towards newer methods introduced in competency-based medical education curriculum and (2) to know the opinion of students regarding knowledge gained & skill acquired in anatomy through CBME. Materials and Methods: A descriptive cross-sectional study was conducted among second-year MBBS students who had just passed their first year in the month of August 2021 by using a pre-designed and pretested questionnaire sent through google forms to their mails. The inclusion criteria of the study were students who are willing to participate and gave consent were included. The exclusion criteria of the study were students who were absent and refused to give consent were excluded. Data were entered and analyzed in MS-Excel and descriptive statistics like simple frequencies and percentages were used. Results: Approximately 76% of the students were below 20 years of age. Female students (63%) were more when compared to male students (37%). Regarding newer methods, 83% of students agreed with introduction of AETCOM (Attitude, Ethics & Communication skills) whereas only 58% agreed with Vertical integration. Mean score was highest for introduction of Ethics & Communication skills (2.8). Majority (88%) of students marked good for opinion regarding knowledge in gross structure of anatomy and 82% for skill in identifying and locating gross anatomical structure. Conclusion: Importance of newer methods in medical education curriculum has to be addressed to students to make learning active. Evaluation of students attitude regarding effectiveness of newer teaching methods will improve quality of the teaching–learning process.","PeriodicalId":15571,"journal":{"name":"Journal of Dr. NTR University of Health Sciences","volume":"1 1","pages":"215 - 219"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89181888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Praneeth Kadiyala, S. Nannapaneni, Apuroopa Murari, K. Vallabhaneni, N. Damera, R. Diddi
{"title":"Study of intraoperative squash cytology and frozen section diagnosis of central nervous system lesions with histopathological correlation","authors":"Praneeth Kadiyala, S. Nannapaneni, Apuroopa Murari, K. Vallabhaneni, N. Damera, R. Diddi","doi":"10.4103/jdrntruhs.jdrntruhs_51_21","DOIUrl":"https://doi.org/10.4103/jdrntruhs.jdrntruhs_51_21","url":null,"abstract":"Context: Intraoperative evaluation of central nervous system (CNS) lesions helps to guide the management by providing preliminary diagnosis, confirming the presence or absence of a neoplasm. Squash cytology and frozen section are reliable and sensitive techniques for rapid intraoperative diagnosis. However, both have respective limitations and the choice of the technique depends on individual preference and tissue availability. Aims: This study aims to determine the diagnostic accuracy of intraoperative squash cytology and frozen section diagnosis by correlating with the final histopathological diagnosis. Settings and Design: Prospective study over a span of 2 years in a tertiary care center. Materials and Methods: A total of 64 cases were subjected to intraoperative squash cytology and frozen section study and the intraoperative diagnosis was compared with final histopathological diagnosis. Statistical Analysis Used: Diagnostic accuracy, sensitivity, specificity, positive predictive value, and negative predictive value. Results: Out of the 64 cases, 86% cases were neoplastic and 14% cases were non-neoplastic. The overall diagnostic accuracy of squash cytology was 90.6% and frozen section was 93.7%. Conclusion: Squash cytology and frozen section are highly accurate and reliable techniques for intraoperative frozen section evaluation of CNS lesions. However, both the techniques have respective limitations. When combined together they help improve the overall diagnostic accuracy.","PeriodicalId":15571,"journal":{"name":"Journal of Dr. NTR University of Health Sciences","volume":"101 1","pages":"181 - 185"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79723273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Karanam, Anil . Kumar, A. Tyagi, Tushar Sharma, M. Suchitra, KV Siva
{"title":"Changes in renal function following per cutaneous nephro lithotomy in chronic kidney disease patients with symptomatic renal calculus disease","authors":"S. Karanam, Anil . Kumar, A. Tyagi, Tushar Sharma, M. Suchitra, KV Siva","doi":"10.4103/jdrntruhs.jdrntruhs_150_20","DOIUrl":"https://doi.org/10.4103/jdrntruhs.jdrntruhs_150_20","url":null,"abstract":"Introduction: Preserving renal function is the Achilles heel in the management of chronic kidney disease (CKD) patient due to the influence of multiple factors in its progression both reversible and irreversible. Renal calcular disease has both cause-and-effect relationship with CKD. Symptomatic renal calcular disease in a CKD patient gives an opportunity to preserve renal function to a variable extent depending on the stage of CKD as well as other comorbities of the patient. Percutaneous nephro lithotripsy is one of the best modalities to relieve obstructed renal tracts and its beneficial effects are established in patients with normal renal function however its efficacy in preserving renal function in CKD patients is less well studied, hence we have undertaken this study. Materials and Methods: A prospective observational study was done to study the changes in renal function as assessed by eGFR and Sr creatinine following Per Cutaneous Nephro Lithotripsy at 0-, 1-, and 3-months interval in CKD patients with symptomatic renal calculus disease. Repeated measure ANNOVA test followed by multiple comparison test was applied to study the outcome. P < 0.05 was considered statistically significant. Results: A total of 60 patients were studied, 80% were male and 20% female. Mean age of the patients in our study was 50.66 ± 13.82 years. out of 60 patients, 36.7% patients had diabetes mellitus, 55% patients had hypertension, and 11.6% had coronary heart disease. The most common presenting symptom was pain 70%, followed by recurrent fever. Most of the patients belong to CKD stage IV (30%). 65% showed improvement in renal function, 25% has stabilization in renal function, and only 10% showed deterioration of renal function. The complication rate was 23%. Discussion and Conclusion: In our study male to female patients' ratio was 4:1 and the most common presenting symptom is flank pain (70%). The renal function improved or stabilized in 90% of patients which was high compared to other studies and deteriorated in 10% patients. PCNL has favourable outcomes in CKD patients with improvement in eGFR, good clearance rate, and low secondary procedure rates. CKD Patients with age above 60 years and having both Diabetes Mellitus and Hypertension may not show significant improvement in Serum creatinine and eGFR. In conclusion, CKD patients can be benefitted by PCNL with good improvement of eGFR and acceptable morbidity when aggressive preoperative stabilization is being done.","PeriodicalId":15571,"journal":{"name":"Journal of Dr. NTR University of Health Sciences","volume":"68 1","pages":"165 - 170"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88397839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The necessity, barriers and strategies to overcome the barriers in evaluation in medical education","authors":"S. Shrivastava, P. Shrivastava","doi":"10.4103/jdrntruhs.jdrntruhs_112_21","DOIUrl":"https://doi.org/10.4103/jdrntruhs.jdrntruhs_112_21","url":null,"abstract":"The curriculum delivered to medical students as a part of their training program has to be multi-faceted, dynamic and should have the component of quality assurance and continuous quality improvement to ensure that competent medical graduates are produced. This review has been carried out to understand the necessity, acknowledge the presence of barriers, and identify the strategies that can be planned to ensure systematic evaluation in medical education. An extensive search of all materials related to the topic was carried out in the PubMed search engine and a total of 15 research articles were included in the review. Keywords used in the search include evaluation and medical education in the title alone only. There are no doubts that evaluation of medical education is an indispensable component of the learning cycle. Nevertheless, we cannot ignore the fact that the overall process of evaluation is complex, predominantly because of the long time interval between the introduction of the educational intervention and the learning outcome. We realize that there can be multiple barriers in the evaluation process in the field of medical education, but we have to overcome these challenges to ensure that the process of evaluation eventually benefits the administrators, teachers and the students. In conclusion, evaluation in medical education is an indispensable component of the training process. However, considering that multiple factors can determine the quality of evaluation, it is essential that specific steps are taken to eliminate these factors and ensure that the findings are valid and that they can be used for remedial actions.","PeriodicalId":15571,"journal":{"name":"Journal of Dr. NTR University of Health Sciences","volume":"8 1","pages":"161 - 164"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86271661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Screening and assessment of mental health issues in patients with COVID-19","authors":"Sarath Bodepudi, Srikanth Lella, Therissa Benerji, Roshan Miyan, Himaja Palagulla, M. Kodali","doi":"10.4103/jdrntruhs.jdrntruhs_19_22","DOIUrl":"https://doi.org/10.4103/jdrntruhs.jdrntruhs_19_22","url":null,"abstract":"Context: COVID-19 pandemic has an impact on the mental health of the most vulnerable populations, especially those afflicted with the disease. Psychological consequences can be due to disease progression, perceived danger, fear of virus transmission to others, uncertainty, and physical discomfort among others. Aim: To screen for mental health issues and to assess the levels of anxiety and depression in patients with COVID-19. Setting and Design: Designed as a cross-sectional study conducted in district COVID-19 hospital. Methods and Material: A cross-sectional study was conducted involving 510 hospitalized patients with COVID-19 between 18 and 60 years of age. Screening instrument of clinical schedule for clinical psychiatry version 2.3 was applied to screen for common psychiatric disorders and Hospital Anxiety and Depression Scale was applied to assess the levels of anxiety and depression in these patients. Statistical Analysis Used: Data were analysed using SPSS version 25. Results: The mean age of our sample was 38.7 years. Panic disorder followed by generalized anxiety disorder, depressive disorder, and alcohol use disorder was the most frequent psychiatric disorder in our sample of participants. Fear of infection with Corona virus was observed to be greater among the patients with COVID-19 screened for mental illnesses, and they were at an increased risk of developing symptoms of anxiety and depression. Conclusion: COVID-19 has a significant psychological impact on the mental health of those afflicted with the disease.","PeriodicalId":15571,"journal":{"name":"Journal of Dr. NTR University of Health Sciences","volume":"347 1","pages":"227 - 232"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90177031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phenotypic detection of ESBL-producing Enterobacteriaceae using combined disk diffusion, ESBL HiCrome agar, and E-test: A comparative study","authors":"S. Dash, S. Sahu, B. Paty","doi":"10.4103/jdrntruhs.jdrntruhs_105_21","DOIUrl":"https://doi.org/10.4103/jdrntruhs.jdrntruhs_105_21","url":null,"abstract":"Background: Extended-spectrum beta-lactamases (ESBLs) are in a rising trend in recent years, creating confusion for physicians to choose appropriate antimicrobials for treatment. Aim: The aim of the study is to detect ESBL-producing Enterobacteriaceae by using rapid detection tests such as combined disk diffusion, ESBL E-test strips (based on cefotaxime and cefotaxime+clavulanate), and ESBL HiCrome agar and compare the efficacy of these tests. Materials and Methods: Samples were processed using conventional methods. Bacterial antibiotic susceptibility testing was done on Mueller-Hinton agar according to the Clinical and Laboratory Standards Institute guidelines. All Enterobacteriaceae isolates were subjected to ESBL HiCrome agar, combined disk diffusion, and E-test. Results: Out of 5299 samples, 2097 (39.57%) were culture-positive, and 200 (9.5%) Enterobacteriaceae isolates were obtained. The majority of the isolates were Escherichia coli (67.5%), followed by Klebsiella pneumoniae (25%), Proteus mirabilis (3.5%), Proteus vulgaris (2%), and Citrobacter freundii (2%). 29.5% of all Enterobacteriaceae isolates were found to be ESBL producers by combined disk diffusion, ESBL HiCrome agar, and E-test methods, which showed 100% concordance. Conclusion: It is important to identify ESBL-producing Enterobacteriaceae from clinical samples for the judicious use of antibiotics. For early detection of ESBL-producing Enterobacteriaceae isolates, combined disk diffusion, ESBL HiCrome agar, and E tests were found to be equally effective in detecting ESBL production.","PeriodicalId":15571,"journal":{"name":"Journal of Dr. NTR University of Health Sciences","volume":"207 1","pages":"200 - 207"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76538598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}