{"title":"Survival Outcomes and Factors Affecting Prognosis in Patients with Head and Neck Region Mucoepidermoid Carcinoma Treated with Adjuvant Radiotherapy","authors":"Mursel DUZOVA, Mustafa AKIN","doi":"10.16899/jcm.1345383","DOIUrl":"https://doi.org/10.16899/jcm.1345383","url":null,"abstract":"Aim: This study aims to ascertain the clinical and pathological factors linked to the outcomes of patients subjected to surgical intervention and postoperative radiotherapy for mucoepidermoid carcinoma (MEC) originating from both major and minor salivary glands in the head and neck region.
 Material and Method: In this retrospective review, medical records of 42 patients who underwent surgery and subsequent radiotherapy for localized MEC in the major and minor salivary glands of the head and neck were analyzed to identify clinicopathological determinants of overall survival. Secondary endpoints encompassed local-regional control, distant metastasis-free survival, and disease-free survival.
 Results: The median age of the patient cohort was 56 years, comprising 52.4% males and 47.6% females. The median follow-up period spanned 36 months, with a range of 6 to 88 months. All patients underwent curative surgery, followed by adjuvant radiotherapy. The 2-year and 5-year rates for overall survival (OS), local-regional recurrence-free survival (LRFS), distant metastasis-free survival (DMFS), and disease-free survival (DFS) were 92% and 72.6%, 92.2% and 85.6%, 84.8% and 73%, 82% and 67.3%, respectively. Notably, only histologic grade emerged as a statistically significant prognostic factor, influencing both OS (p=0.019), DMFS (p=0.014), and DFS (p=0.044).
 Conclusion: The histologic grade of the tumor is the foremost determinant impacting the outcomes of MEC cases. Adjuvant radiotherapy is recommended for high-grade tumors, while its application for low-grade and intermediate-grade tumors should be individualized based on the anticipated risk of recurrence. This underscores the significance of tailoring treatment approaches according to histologic characteristics.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prematüre erken kontraksiyon ile ilgili YouTube videolarının kalite ve güvenilirliğinin değerlendirilmesi","authors":"Kemal GÖÇER","doi":"10.16899/jcm.1342668","DOIUrl":"https://doi.org/10.16899/jcm.1342668","url":null,"abstract":"Aim: 
 The internet is a popular and continually utilized platform to gain medical knowledge for patients and health professionals. This research aimed to evaluate the accuracy and quality of videos for premature ventricular contraction (PVC) on YouTube.
 Material and method: The keyword \"premature ventricular contraction\" was inputted into the YouTube search engine. The 60 most watched videos on YouTube were analyzed. Six of these were excluded from the study. A total of 54 patients were included in the study. General characteristics of the videos were recorded. Two specialist physicians reviewed all videos. GQS, DISCERN, and JAMA scoring systems were used to test the video quality and reliability. Video quality was divided into three groups according to the GQS score. Video characteristics were compared between quality groups.
 Results: 37% of the videos posted were from doctors, and the most frequently seen content was related to general information about PVCs, accounting for 70.4%. There were 24 high-quality videos. The number of video comments (p=0.006), daily view rate (p=0.001), JAMA (p=","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Selektif IgE Eksikliği ve Otoimmun Hastalık İlişkisi","authors":"Nurhan SAYACA","doi":"10.16899/jcm.1350196","DOIUrl":"https://doi.org/10.16899/jcm.1350196","url":null,"abstract":"Abstract
 Introduction and Aim: Selective IgE deficiency (SIgED) is currently defined as a significant decrease in serum levels of IgE (≤2 kIU/L) in a patient whose other immunoglobulin levels are normal. The clinical spectrum of SIgED is unknown still. This study aimed to determine the relationship between SIgED and autoimmune diseases in an allergy and immunology clinic of a university hospital.
 Methods: A retrospective study of the data obtained from medical records of 40 patients, 27 were female (67.5%), and the mean age was 39 years (range 20–69 years) and IgE levels of ≤2.0 kIU/L with normal immunoglobulin (Ig) IgG, IgA, and IgM levels.
 Results: A total of 40 patients , 27 females (67.5 %) and 13 males (32.5%), were included in the study. The mean age of the patients was 39 ±13.06 years (range 20–69). In the present study, 35% of patients had an autoimmune disease (N:14), however 65% of patients did not have any autoimmune disease (N:26). Hashimoto’s thyroiditis being the most frequent (N:6) in 15% which is followed by systemic lupus erythematosus (SLE) (N:3) in 7.5%, celiac disease (N: 2) in 5%, chronic spontaneous urticaria (CSU) (N:1) in 2.5%, vitiligo (N:1) in 2.5%, type 1 diabetes mellitus (DM) (N:1) in 2.5%. 
 Conclusion: SIgED, should be defined clearly with cut-off values of IgE. Physicians should show more attention to the low IgE values and investigate patients about autoimmune diseases which can be seen together with SIgED. More studies should be conducted to investigate associated diseases with SIgED.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Vitamin B12, Folic Acid, Ferritin and Vitamin D Levels in Obsessive Compulsive Disorder","authors":"Okan İMRE, Rahim KOCABAŞ","doi":"10.16899/jcm.1335202","DOIUrl":"https://doi.org/10.16899/jcm.1335202","url":null,"abstract":"Aims: Obsessive compulsive disorder (OCD) is a heterogeneous disorder characterized by obsessions and compulsions. Despite the studies, etiopathogenesis is not fully understood. Pharmacological and psychosocial interventions in OCD may be insufficient due to limited knowledge of etiopathogenesis. Therefore, it is important to find inexpensive and easily determined biochemical parameters related to etiopathogenesis. In this study, the relationship between OCD and vitamin B12 (VitB12), folic acid (FA), vitamin D (VitD) and ferritin was investigated.
 Material and Method: 50 patients with OCD (12 female, 38 male) and 50 healthy controls (HC) (13 female, 37 male) were included in this retrospective study. Serum VitB12, FA, ferritin and 25-OH VitD levels of both groups were compared.
 Results: VitB12 (p","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Meme Kanseri Tanısı Almış Kadınlarda Beslenme Durumu, Yaşam Kalitesi ve Akdeniz Diyetine Bağlılığın Değerlendirilmesine İlişkin Bir Araştırma","authors":"Yekta ÇAPALI ŞAHİN, Sine YILMAZ","doi":"10.16899/jcm.1350836","DOIUrl":"https://doi.org/10.16899/jcm.1350836","url":null,"abstract":"Aim: The aim of this study is to assess the quality of life and adherence to the Mediterranean diet (MD) among female breast cancer patients.
 Material and Method: The study included a cohort of 120 women who received a breast cancer diagnosis within the last year. Anthropometric measurements were conducted, and body composition analysis was carried out to determine body fat percentage. The Mediterranean Diet Adherence Scale (MEDAS) and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) were employed for data collection.
 Results: A total of 120 breast cancer patients, with an average age of 49.8±10.56 years, were enrolled in the study. Among these participants, 42.5% were categorized as having a normal weight. The mean waist circumference and waist/hip ratio were 94.6±12.20 cm and 0.87±0.10, respectively. Body fat percentages were determined to be 36.8±8.61%. The average total energy intake was 1944.9±385.24 kcal, with the percentage of total fat intake from energy averaging at 35.6±4.81%. Patients had a mean body mass index (BMI) of 29.0±5.80 kg/m², with 40.8% of them classified as obese. The mean MEDAS score was 7.3±2.65, and the EORTC QLQ-C30 score averaged at 69.7±11.94. There is a negative correlation was found between BMI, waist circumference and MEDAS score; A positive correlation was found between MEDAS scores and EORTC scores.
 Conclusion: Breast cancer patients with high compliance with the Mediterranean diet have a higher quality of physical, emotional and social life. Therefore, evaluation of modifiable risk factors in breast cancer patients is essential for the prognosis of the disease.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Global Histeroskopi ve Kadın İnfertilitesi Araştırmalarının Mevcut Durumu: Web of Science Tabanlı Bibliyometrik Analiz Çalışması","authors":"Özgür ŞAHİN","doi":"10.16899/jcm.1343842","DOIUrl":"https://doi.org/10.16899/jcm.1343842","url":null,"abstract":"Abstract
 
 Aim: The aim of this study was to identify trends in the literature on hysteroscopy and female infertility and to quantitatively evaluate them using various bibliometric parameters.
 
 Material and Methods: The study data was taken from the Web of Science electronic database for this bibliometric network analysis. The network analysis and bibliometric analysis were carried out by using the Biblioshiny and VosViewer bibliometric tools.
 
 Results: A total of 1,023 documents were included in the study. The first article was published in 1977. Until 1990, the annual number of articles was irregular. The quantity of publications published annually significantly increased after 2005, peaking in 2020 and 2021 (68 and 67 articles, respectively). The included articles were published in 67 countries. Among these countries, China (n=299), the USA (n=237), Italy (n=235), and Turkey (n=156) had the highest number of publications. Especially after 2012, there has been a significant increase in Chinese publications. In addition, 10.07% of the documents had co-authors from other countries. The keywords 'hysteroscopy (frequency 422), hysterosalpingography office (frequency 65), hysteroscopy (frequency 49), and chronic endometritis (frequency 45') topped the trending topic list.
 
 Conclusion: It is notable that among international publications, Chinese publications have increased significantly, especially in the last decade. Funding support from Chinese institutions may be responsible for this","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of Variants In SARS-CoV-2 Infections after Three Doses of COVID-19 Vaccine","authors":"Burcu GÜRER GİRAY, Gökçe GÜVEN AÇIK","doi":"10.16899/jcm.1343574","DOIUrl":"https://doi.org/10.16899/jcm.1343574","url":null,"abstract":"Abstract
 Objective: Our study focused on retrospectively assessing variant of concern, specified by the World Health Organization (WHO), with one-step reverse transcription and real-time polymerase chain reaction (RT-PCR) test in SARS-CoV-2 positive patients after three doses of attenuated COVID-19 vaccine.
 Methods: 8.520 samples transported with viral nucleic acid buffer (vNAT) tubes between June 2021 and January 31, 2022, were tested and included in the study. All the patients whose samples were included in our research had 3 doses of CoronaVac (Sinovac Life Science Co, Ltd, Beijing, China). Gender distribution was 4686 (55%) female and 3834 ( 45%) males. Variant specific genome regions only found in B.1.351, P.1 and B.1.1.7 as well as ORF1ab and N gene regions are investigated by the Bio-Speedy® Emerging Plus kit (Bioeksen AR-GE Technologies, Turkey) used to identify the variants in the study.
 Results: All 8.520 samples were SARS-CoV-2 RT-PCR positive. Our study detected alpha and delta variants in 1460 (17.14%) and 3570 (41.9%) patients respectively. 2570 (30.16%) patients did not have any variants according to test results. It was observed that the spread of beta, gamma and other suspicious variants remained at relatively low rates.
 Conclusion: The delta variant became dominant from July until to the end of the year. Declining delta variant rates and increasing cases of suspected variants towards the beginning of December 2021 suggest the omicron variant. Therefore, molecular surveillance studies that are planned to take epidemiological data into consideration and to examine the prevalence and gene-based analysis of local and worldwide variants are required.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mustafa Cüneyt ÇİÇEK, Mustafa DAĞLI, A Nihat BAYSAL, Emin BARBARUS, Hayat GÖKMENGİL, Hüseyin DURMAZ, İlyas Selim YILMAZ, Yalçın GÜNERHAN, Kadir DURGUT
{"title":"Alt Ekstremite Periferik Arter Hastalığında Endovasküler Girişimlerden Kaynaklanan Akut Komplikasyonların Cerrahi Yönetimi: Eskimeyen Yeni","authors":"Mustafa Cüneyt ÇİÇEK, Mustafa DAĞLI, A Nihat BAYSAL, Emin BARBARUS, Hayat GÖKMENGİL, Hüseyin DURMAZ, İlyas Selim YILMAZ, Yalçın GÜNERHAN, Kadir DURGUT","doi":"10.16899/jcm.1348296","DOIUrl":"https://doi.org/10.16899/jcm.1348296","url":null,"abstract":"Aim: The importance of endovascular procedures in the diagnosis and treatment of peripheral vascular diseases has seen a notable rise in recent years. Nevertheless, this surge has resulted in a corresponding rise in iatrogenic vascular complications and subsequent interventions associated with peripheral endovascular procedures. This study involved a retrospective evaluation of acute complications associated with endovascular treatments performed for lower limb peripheral artery diseases, as well as a closer look of the related therapeutic strategies for these challenges.
 Materials and Methods: A retrospective evaluation was conducted on a cohort of 400 patients who received endovascular intervention for lower extremity peripheral artery disease at our clinic. The study included 27 patients (6.7%) from this cohort who received surgical or endovascular treatment for acute complications following endovascular intervention. Our preference for endovascular or surgical treatments was chosen based on the type and localization of the complications.
 Results: The mean age of patients who experienced complications was 63.7±6 years. The complications were as follows in order of frequency: dissection 14 (51.9%) patients, arterial perforation 5 (18.5%) patients, major hematoma 3 (11.1%) patients, pseudoaneurysm 2 (7.4%) patients, distal embolism 2 (7.4%) patients and arterio-venous fistula 1 (3.7%) patient. In the treatment of complications, endovascular methods were preferred in 19 (4.7%) patients and surgical approaches were used in 8 (2%) patients. Following endovascular intervention, minor amputation was performed in one patient.
 Conclusion: The rapid and effective management of complications related to peripheral endovascular procedures in the lower extremities is of utmost importance. Despite the notable advancements in endovascular procedures in recent years, there are scenarios where these interventions may be insufficient for dealing with complications. The management of such problems may necessitate surgical intervention. Hence, the integration of well-established and validated vascular surgical techniques with endovascular interventions is believed to yield optimal outcomes.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Solunum Yoğun Bakım Ünitesinde Perkütan Endoskopik Gastrostominin Klinik Sonuçları","authors":"Kamuran ULUÇ, Esra AKKÜTÜK ÖNGEL, Nazan KÖYLÜ İLKAYA, Özkan DEVRAN, Ernur AY, Hatice KUTBAY ÖZÇELİK","doi":"10.16899/jcm.1331937","DOIUrl":"https://doi.org/10.16899/jcm.1331937","url":null,"abstract":"Aim: Percutaneous endoscopic gastrostomy (PEG) is a feeding method used in patients who are expected to require enteral nutrition for more than 2-3 weeks. We aimed to evaluate PEG indications, complications, and post-procedural patient prognosis in patients followed up in our intensive care unit and fed via PEG.
 Materials and Methods: We retrospectively reviewed 51 patients receiving PEG between January 1, 2017, and December 31, 2022, in the Respiratory Intensive Care Unit.
 Results: Among the patients receiving PEG, 30 (58%) were male. The average age was 63.9, ranging from 23 to 90. The mean scores for the Glasgow Coma Scale (GCS), Acute Physiology and Chronic Health Evaluation II (APACHE II), and Sepsis Related Organ Failure Assessment (SOFA) were 8.47, 22, and 7.45, respectively. The mean duration until PEG placement was 24.8 days, and the average intensive care unit (ICU) hospitalization was 48.8 days.PEG was performed in 21 patients (41.2%) due to cerebrovascular disease, in 19 patients (37.3%) due to Alzheimer, dementia, or Parkinson's disease, and 18 patients (35.3%) due to prolonged mechanical ventilation. The complication rate associated with PEG was 13.7%. Among the patients who underwent PEG, 35 (68.6%) were discharged, while 16 (31.4%) died.
 Conclusion: Considering its easy use at bedside, low complication, and mortality rates, PEG insertion is appropriate for continuing enteral therapies, especially in intensive care patients with insufficient oral intake.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Neurofibromatosis Type 1 Associated Optic Pathway Gliomas","authors":"Özge VURAL, Arzu OKUR, Faruk Güçlü PINARLI","doi":"10.16899/jcm.1350153","DOIUrl":"https://doi.org/10.16899/jcm.1350153","url":null,"abstract":"Background/Aims: Optic pathway gliomas (OPGs) are low-grade gliomas histologically represented by pilocytic astrocytoma (PA) in 90% of cases, can develop from any part of the visual pathways such as optic nerve, chiasm, optic tract, or optic radiations which frequently involve the hypothalamus. OPGs account for 3–5% of childhood central nervous system (CNS) tumors and about 2% of pediatric glial lesions. OPGs are believed to be the most prevalent intracranial tumor in patients with neurofibromatosis type 1 (NF-1) and can occur in 15–20% of NF-1 cases. The aim of this study is to evaluate the clinical features and treatment response in patients diagnosed with optic glioma and NF-1.
 Methods: All cases diagnosed with OPG and received treatment in the Pediatric Oncology Department, between January 2015 to January 2021 were retrospectively evaluated. Inclusion criteria include children and adolescents with OPG aged between 0 and 18 years. The medical records (gender, age, tumor entity, tumor location) of patients, as well as their treatment history and magnetic resonance imaging (MRI) scans, were examined. The diagnosis of OPG was made clinically and radiologically by the tumor board. The recommendations of the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group were used in the diagnosis and evaluation of treatment response. Patients received intravenous chemotherapy with SIOP LGG 2004 (vincristine- carboplatin) with or without bevacizumab (10 mg/kg, started every 2 weeks), therapy or vinblastine (3 mg/m2, weekly). 
 Results: This study included 27 cases during the study period from January 2015 to January 2021. In this study there were 14 male (51.8 %) and 13 female (48.1 %) patients. The median age was 4.8 (range: 0.5–14.9) years. Biopsy was performed in three patients and the diagnosis was low-grade glioma (pilocytic astrocytoma) for all of them. Chemotherapy was administered to 22 cases in total. Twelve patients received vincristine-carboplatine, 5 patients received vincristine-carboplatin with bevacizumab and 5 patients received vinorelbine. Radiological response was evaluated in all 22 patients at 3 months MRI. No patient had a radiological complete respons, 11 patients (50%) had partial response, 2 patients (9%) presented with a progressive disease, showing an increase in measurements of 35% and 9 patients(40.9%) had stable disease at the 3-month evaluation.
 Conclusions: Systemic and visual problems play a significant role in the selection of treatment for pediatric patients with optic gliomas. An essential treatment option for improving symptoms and reducing tumor size is systemic chemotherapy. A crucial therapy option for enhancing vision is bevacizumab for the patients with NF-associated OPG.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}