Journal of contemporary medicine最新文献_第5页

Karbon Monoksit Zehirlenmesi Olan Çocuklarda Sistemik İmmün İnflamasyon İndeksinin Prognostik Değeri 一氧化碳中毒儿童全身免疫炎症指数的预后价值

Journal of contemporary medicine Pub Date : 2023-09-30 DOI: 10.16899/jcm.1347034

Emine ÖZDEMİR KAÇER

引用次数: 0

Liver Protection of Hydroxytyrosol Mediated by Spexin and TRPM2 Spexin和TRPM2对羟基酪醇的肝脏保护作用

Journal of contemporary medicine Pub Date : 2023-09-30 DOI: 10.16899/jcm.1352503

Elif ONAT, Nevin KOCAMAN

引用次数: 1

Frequency of Rotavirus and Adenovirus in Children with Diarrhea 腹泻患儿轮状病毒和腺病毒的发病率

Journal of contemporary medicine Pub Date : 2023-09-30 DOI: 10.16899/jcm.1316829

Hülya DURAN, Fadime YILMAZ YÜCEL

{"title":"Frequency of Rotavirus and Adenovirus in Children with Diarrhea","authors":"Hülya DURAN, Fadime YILMAZ YÜCEL","doi":"10.16899/jcm.1316829","DOIUrl":"https://doi.org/10.16899/jcm.1316829","url":null,"abstract":"ABSTRACT Aim: The aim of this study is retrospective evaluation of the frequency of rotavirus and adenovirus in stool, and their distribution according to gender, age and seasons in children with diarrhea admitted at outpatients or hospitalized in our hospital. Material and Methods: Stool samples of patients aged between 0-18 years received at the Medical Microbiology Laboratory between 2021–2022 were evaluated for rotavirus–adenovirus. Rotavirus and adenovirus antigens were determined qualitatively by immunochromatographic cassette test method. Chi-square test was used in the statistical analysis. Results: A total of 1148 stool samples of pediatric patients were received by our laboratory during these two years for rotavirus and adenovirus antigen test. Of 1148 patients, 8.6% were positive for rotavirus, 5.1% for adenovirus, and 0.6% for both rotavirus and adenovirus antigens. Rotavirus and adenovirus was positive in 7.2% and 5.6% of males, respectively, and 10.6% and 4.5% of females, and there were no statistically significant differences. Rotavirus was most frequently found in the age group 3-5 years (11.6%) and adenovirus was most frequently found in the age group 6-9 years (8.4%), with no significant difference. Rotavirus was most frequently detected in spring (12.9%) while adenovirus was found most frequently in winter (8.1%), without significant differences. Antigen positivity was 4.1% and 4.9% in outpatients for rotavirus and adenovirus, respectively, and 15.1% and 5.5% in hospitalized patients. Rotavirus positivity was significantly higher in hospitalized patients than outpatients, and adenovirus positivity did not show a significant difference. Conclusion: We found that rotavirus and adenovirus were significant agents causing diarrhea in children, especially those younger than 5 years old, and that its frequency increased in winter and spring, and as rotavirus is a cause of hospitalization, implementation of rotavirus vaccine into routine vaccination programs seem to be beneficial for patients.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survival Outcomes and Factors Affecting Prognosis in Patients with Head and Neck Region Mucoepidermoid Carcinoma Treated with Adjuvant Radiotherapy 头颈部黏液表皮样癌辅助放疗患者的生存结局及影响预后的因素

Journal of contemporary medicine Pub Date : 2023-09-30 DOI: 10.16899/jcm.1345383

Mursel DUZOVA, Mustafa AKIN

{"title":"Survival Outcomes and Factors Affecting Prognosis in Patients with Head and Neck Region Mucoepidermoid Carcinoma Treated with Adjuvant Radiotherapy","authors":"Mursel DUZOVA, Mustafa AKIN","doi":"10.16899/jcm.1345383","DOIUrl":"https://doi.org/10.16899/jcm.1345383","url":null,"abstract":"Aim: This study aims to ascertain the clinical and pathological factors linked to the outcomes of patients subjected to surgical intervention and postoperative radiotherapy for mucoepidermoid carcinoma (MEC) originating from both major and minor salivary glands in the head and neck region. Material and Method: In this retrospective review, medical records of 42 patients who underwent surgery and subsequent radiotherapy for localized MEC in the major and minor salivary glands of the head and neck were analyzed to identify clinicopathological determinants of overall survival. Secondary endpoints encompassed local-regional control, distant metastasis-free survival, and disease-free survival. Results: The median age of the patient cohort was 56 years, comprising 52.4% males and 47.6% females. The median follow-up period spanned 36 months, with a range of 6 to 88 months. All patients underwent curative surgery, followed by adjuvant radiotherapy. The 2-year and 5-year rates for overall survival (OS), local-regional recurrence-free survival (LRFS), distant metastasis-free survival (DMFS), and disease-free survival (DFS) were 92% and 72.6%, 92.2% and 85.6%, 84.8% and 73%, 82% and 67.3%, respectively. Notably, only histologic grade emerged as a statistically significant prognostic factor, influencing both OS (p=0.019), DMFS (p=0.014), and DFS (p=0.044). Conclusion: The histologic grade of the tumor is the foremost determinant impacting the outcomes of MEC cases. Adjuvant radiotherapy is recommended for high-grade tumors, while its application for low-grade and intermediate-grade tumors should be individualized based on the anticipated risk of recurrence. This underscores the significance of tailoring treatment approaches according to histologic characteristics.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prematüre erken kontraksiyon ile ilgili YouTube videolarının kalite ve güvenilirliğinin değerlendirilmesi 评估 YouTube 早产儿宫缩视频的质量和可靠性

Journal of contemporary medicine Pub Date : 2023-09-30 DOI: 10.16899/jcm.1342668

Kemal GÖÇER

引用次数: 0

Selektif IgE Eksikliği ve Otoimmun Hastalık İlişkisi 选择性 IgE 缺乏症和自身免疫性疾病

Journal of contemporary medicine Pub Date : 2023-09-30 DOI: 10.16899/jcm.1350196

Nurhan SAYACA

{"title":"Selektif IgE Eksikliği ve Otoimmun Hastalık İlişkisi","authors":"Nurhan SAYACA","doi":"10.16899/jcm.1350196","DOIUrl":"https://doi.org/10.16899/jcm.1350196","url":null,"abstract":"Abstract Introduction and Aim: Selective IgE deficiency (SIgED) is currently defined as a significant decrease in serum levels of IgE (≤2 kIU/L) in a patient whose other immunoglobulin levels are normal. The clinical spectrum of SIgED is unknown still. This study aimed to determine the relationship between SIgED and autoimmune diseases in an allergy and immunology clinic of a university hospital. Methods: A retrospective study of the data obtained from medical records of 40 patients, 27 were female (67.5%), and the mean age was 39 years (range 20–69 years) and IgE levels of ≤2.0 kIU/L with normal immunoglobulin (Ig) IgG, IgA, and IgM levels. Results: A total of 40 patients , 27 females (67.5 %) and 13 males (32.5%), were included in the study. The mean age of the patients was 39 ±13.06 years (range 20–69). In the present study, 35% of patients had an autoimmune disease (N:14), however 65% of patients did not have any autoimmune disease (N:26). Hashimoto’s thyroiditis being the most frequent (N:6) in 15% which is followed by systemic lupus erythematosus (SLE) (N:3) in 7.5%, celiac disease (N: 2) in 5%, chronic spontaneous urticaria (CSU) (N:1) in 2.5%, vitiligo (N:1) in 2.5%, type 1 diabetes mellitus (DM) (N:1) in 2.5%.  Conclusion: SIgED, should be defined clearly with cut-off values of IgE. Physicians should show more attention to the low IgE values and investigate patients about autoimmune diseases which can be seen together with SIgED. More studies should be conducted to investigate associated diseases with SIgED.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Vitamin B12, Folic Acid, Ferritin and Vitamin D Levels in Obsessive Compulsive Disorder 强迫症患者维生素B12、叶酸、铁蛋白和维生素D水平的评估

Journal of contemporary medicine Pub Date : 2023-09-30 DOI: 10.16899/jcm.1335202

Okan İMRE, Rahim KOCABAŞ

引用次数: 0

Meme Kanseri Tanısı Almış Kadınlarda Beslenme Durumu, Yaşam Kalitesi ve Akdeniz Diyetine Bağlılığın Değerlendirilmesine İlişkin Bir Araştırma 对确诊乳腺癌妇女的营养状况、生活质量和地中海饮食坚持情况进行评估的研究

Journal of contemporary medicine Pub Date : 2023-09-30 DOI: 10.16899/jcm.1350836

Yekta ÇAPALI ŞAHİN, Sine YILMAZ

{"title":"Meme Kanseri Tanısı Almış Kadınlarda Beslenme Durumu, Yaşam Kalitesi ve Akdeniz Diyetine Bağlılığın Değerlendirilmesine İlişkin Bir Araştırma","authors":"Yekta ÇAPALI ŞAHİN, Sine YILMAZ","doi":"10.16899/jcm.1350836","DOIUrl":"https://doi.org/10.16899/jcm.1350836","url":null,"abstract":"Aim: The aim of this study is to assess the quality of life and adherence to the Mediterranean diet (MD) among female breast cancer patients. Material and Method: The study included a cohort of 120 women who received a breast cancer diagnosis within the last year. Anthropometric measurements were conducted, and body composition analysis was carried out to determine body fat percentage. The Mediterranean Diet Adherence Scale (MEDAS) and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) were employed for data collection. Results: A total of 120 breast cancer patients, with an average age of 49.8±10.56 years, were enrolled in the study. Among these participants, 42.5% were categorized as having a normal weight. The mean waist circumference and waist/hip ratio were 94.6±12.20 cm and 0.87±0.10, respectively. Body fat percentages were determined to be 36.8±8.61%. The average total energy intake was 1944.9±385.24 kcal, with the percentage of total fat intake from energy averaging at 35.6±4.81%. Patients had a mean body mass index (BMI) of 29.0±5.80 kg/m², with 40.8% of them classified as obese. The mean MEDAS score was 7.3±2.65, and the EORTC QLQ-C30 score averaged at 69.7±11.94. There is a negative correlation was found between BMI, waist circumference and MEDAS score; A positive correlation was found between MEDAS scores and EORTC scores. Conclusion: Breast cancer patients with high compliance with the Mediterranean diet have a higher quality of physical, emotional and social life. Therefore, evaluation of modifiable risk factors in breast cancer patients is essential for the prognosis of the disease.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global Histeroskopi ve Kadın İnfertilitesi Araştırmalarının Mevcut Durumu: Web of Science Tabanlı Bibliyometrik Analiz Çalışması 全球宫腔镜和女性不孕症研究现状：基于科学网的文献计量分析

Journal of contemporary medicine Pub Date : 2023-09-30 DOI: 10.16899/jcm.1343842

Özgür ŞAHİN

{"title":"Global Histeroskopi ve Kadın İnfertilitesi Araştırmalarının Mevcut Durumu: Web of Science Tabanlı Bibliyometrik Analiz Çalışması","authors":"Özgür ŞAHİN","doi":"10.16899/jcm.1343842","DOIUrl":"https://doi.org/10.16899/jcm.1343842","url":null,"abstract":"Abstract  Aim: The aim of this study was to identify trends in the literature on hysteroscopy and female infertility and to quantitatively evaluate them using various bibliometric parameters.  Material and Methods: The study data was taken from the Web of Science electronic database for this bibliometric network analysis. The network analysis and bibliometric analysis were carried out by using the Biblioshiny and VosViewer bibliometric tools.  Results: A total of 1,023 documents were included in the study. The first article was published in 1977. Until 1990, the annual number of articles was irregular. The quantity of publications published annually significantly increased after 2005, peaking in 2020 and 2021 (68 and 67 articles, respectively). The included articles were published in 67 countries. Among these countries, China (n=299), the USA (n=237), Italy (n=235), and Turkey (n=156) had the highest number of publications. Especially after 2012, there has been a significant increase in Chinese publications. In addition, 10.07% of the documents had co-authors from other countries. The keywords 'hysteroscopy (frequency 422), hysterosalpingography office (frequency 65), hysteroscopy (frequency 49), and chronic endometritis (frequency 45') topped the trending topic list.  Conclusion: It is notable that among international publications, Chinese publications have increased significantly, especially in the last decade. Funding support from Chinese institutions may be responsible for this","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of Variants In SARS-CoV-2 Infections after Three Doses of COVID-19 Vaccine 三剂COVID-19疫苗后SARS-CoV-2感染变异的调查

Journal of contemporary medicine Pub Date : 2023-09-30 DOI: 10.16899/jcm.1343574

Burcu GÜRER GİRAY, Gökçe GÜVEN AÇIK

{"title":"Investigation of Variants In SARS-CoV-2 Infections after Three Doses of COVID-19 Vaccine","authors":"Burcu GÜRER GİRAY, Gökçe GÜVEN AÇIK","doi":"10.16899/jcm.1343574","DOIUrl":"https://doi.org/10.16899/jcm.1343574","url":null,"abstract":"Abstract Objective: Our study focused on retrospectively assessing variant of concern, specified by the World Health Organization (WHO), with one-step reverse transcription and real-time polymerase chain reaction (RT-PCR) test in SARS-CoV-2 positive patients after three doses of attenuated COVID-19 vaccine. Methods: 8.520 samples transported with viral nucleic acid buffer (vNAT) tubes between June 2021 and January 31, 2022, were tested and included in the study. All the patients whose samples were included in our research had 3 doses of CoronaVac (Sinovac Life Science Co, Ltd, Beijing, China). Gender distribution was 4686 (55%) female and 3834 ( 45%) males. Variant specific genome regions only found in B.1.351, P.1 and B.1.1.7 as well as ORF1ab and N gene regions are investigated by the Bio-Speedy® Emerging Plus kit (Bioeksen AR-GE Technologies, Turkey) used to identify the variants in the study. Results: All 8.520 samples were SARS-CoV-2 RT-PCR positive. Our study detected alpha and delta variants in 1460 (17.14%) and 3570 (41.9%) patients respectively. 2570 (30.16%) patients did not have any variants according to test results. It was observed that the spread of beta, gamma and other suspicious variants remained at relatively low rates. Conclusion: The delta variant became dominant from July until to the end of the year. Declining delta variant rates and increasing cases of suspected variants towards the beginning of December 2021 suggest the omicron variant. Therefore, molecular surveillance studies that are planned to take epidemiological data into consideration and to examine the prevalence and gene-based analysis of local and worldwide variants are required.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1