The Siberian Medical Journal最新文献

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ULTRASOUND CONTRAST-ENHANCED STRESS ECHOCARDIOGRAPHY WITH MYOCARDIAL PERFUSION FOR FUNCTIONAL ASSESSMENT OF INTERMEDIATE STENOSIS IN THE LEFT ANTERIOR DESCENDING CORONARY ARTERY IN PATIENT WITH PREMATURE VENTRICULAR COMPLEXE 超声增强应激超声心动图心肌灌注对室性早衰患者左冠状动脉前降支中度狭窄的功能评价
The Siberian Medical Journal Pub Date : 2019-04-23 DOI: 10.29001/2073-8552-2018-34-1-137-144
С. Бессонов, Д. В. Криночкин, А. Кузнецов, А. О. Дьякова, Н. Ю. Хорькова, Н. А. Галеева, I. S. Bessonov, Dmitry V. Krinochkin, Vadim A. Kuznetsov, A. O. Dyakova, Natalia Y. Khorkova, Natalia A. Galeeva, Anastasia A. Takkand
{"title":"ULTRASOUND CONTRAST-ENHANCED STRESS ECHOCARDIOGRAPHY WITH MYOCARDIAL PERFUSION FOR FUNCTIONAL ASSESSMENT OF INTERMEDIATE STENOSIS IN THE LEFT ANTERIOR DESCENDING CORONARY ARTERY IN PATIENT WITH PREMATURE VENTRICULAR COMPLEXE","authors":"С. Бессонов, Д. В. Криночкин, А. Кузнецов, А. О. Дьякова, Н. Ю. Хорькова, Н. А. Галеева, I. S. Bessonov, Dmitry V. Krinochkin, Vadim A. Kuznetsov, A. O. Dyakova, Natalia Y. Khorkova, Natalia A. Galeeva, Anastasia A. Takkand","doi":"10.29001/2073-8552-2018-34-1-137-144","DOIUrl":"https://doi.org/10.29001/2073-8552-2018-34-1-137-144","url":null,"abstract":"The presence of the intermediate stenosis (30 to 50% of arterial diameter) according to coronary angiography in patients with premature ventricular complexes often represents a complicated clinical task and requires additional confirmation of myocardial ischemia. The present clinical case demonstrates the opportunities and potential benefits of contrast-enhanced stress echocardiography with assessment of myocardial perfusion in diagnosing the hemodynamic significance of the intermediate lesion of the left anterior descending artery in patient with premature ventricular complexes.","PeriodicalId":153905,"journal":{"name":"The Siberian Medical Journal","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117128033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
FEATURES OF THE ATTITUDE TOWARDS SMOKING IN CONNECTION WITH THE NATURE OF WORK AND MARITAL STATUS IN OPEN URBAN POPULATION: GENDER DIFFERENCES 开放城市人口对吸烟的态度与工作性质和婚姻状况的关系特点:性别差异
The Siberian Medical Journal Pub Date : 2019-04-23 DOI: 10.29001/2073-8552-2019-34-1-162-169
Gakova Ei, M. Kayumova, A. Gakova, M. Akimov, Kuznetsov Va, V. Gafarov
{"title":"FEATURES OF THE ATTITUDE TOWARDS SMOKING IN CONNECTION WITH THE NATURE OF WORK AND MARITAL STATUS IN OPEN URBAN POPULATION: GENDER DIFFERENCES","authors":"Gakova Ei, M. Kayumova, A. Gakova, M. Akimov, Kuznetsov Va, V. Gafarov","doi":"10.29001/2073-8552-2019-34-1-162-169","DOIUrl":"https://doi.org/10.29001/2073-8552-2019-34-1-162-169","url":null,"abstract":"Aim. To study the attitudes towards smoking in working-age men and women with different nature of work and marital status in Tyumen city.Material and Methods. The cross-sectional epidemiological study was carried out as part of the cardiac screening in open urban male and female population. The study included 850 men (response rate 85.0%) and 704 women (response rate of 70.4%) aged 25–64 years. A self-report questionnaire of the World Health Organization titled «Knowledge and Attitude to Health» with a fixed list of answer options was used to analyze attitudes to smoking. Social status was assessed according to the nature of work (four categories: «unemployed and pensioners», «manual labour», «specialists and technical/engineering employees», and «leaders»), and marital status (have or do not have a life partner). Statistical analysis of the results was conducted using SPSS (11.5) and Statistica 7.0 software packages and Microsoft Excel spreadsheet software. Values were considered statistically significant when p was <0.05.Results. The prevalence of smoking among single men was higher than the corresponding value in men who had a life partner (63.4 vs. 46.6%, р<0.001); the opposite trend was observed in women (13.1 vs. 17.0%, р>0.05). In regard to the nature of work, the highest smoking rate was found among men who were engaged in manual labour (m/f: 60.8/19.8%). Men from the categories of «specialists and technical/engineering employees» and «leaders» (40.7 and 41%) as well as women from the «unemployed and pensioners» category smoked less often (11.6%), (р<0.001). Gender differences in attitudes to smoking depended on marital status and the nature of work. Correlations between the nature of work and attempts to change something in smoking pattern were observed in men (R=0.35, p=0.05) and women (R=0.18, p=0.01).Conclusion. According to the study of open urban population, significant differences were detected between men and women in regard to their attitudes towards smoking. Gender-related differences in the associations of smoking with marital status and the nature of work were identified.","PeriodicalId":153905,"journal":{"name":"The Siberian Medical Journal","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128279983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EFFECT OF PROPRANOLOL ON AEROBIC-HEMODYNAMIC SUPPORT OF PHYSICAL ACTIVITY IN PATIENTS WITH EFFORT ANGINA, POSITIVE ANTIANGINAL ACTION AND THE ABSENCE OF CLINICAL EFFECT AFTER PROPRANOLOL-BASED TREATMENT 心得安对苦力型心绞痛患者体力活动有氧血流动力学支持的影响、积极的抗心绞痛作用及以心得安为主的治疗后无临床效果
The Siberian Medical Journal Pub Date : 2019-04-23 DOI: 10.29001/2073-8552-2018-34-1-118-123
A. Vasilyev, N. Streltsova
{"title":"EFFECT OF PROPRANOLOL ON AEROBIC-HEMODYNAMIC SUPPORT OF PHYSICAL ACTIVITY IN PATIENTS WITH EFFORT ANGINA, POSITIVE ANTIANGINAL ACTION AND THE ABSENCE OF CLINICAL EFFECT AFTER PROPRANOLOL-BASED TREATMENT","authors":"A. Vasilyev, N. Streltsova","doi":"10.29001/2073-8552-2018-34-1-118-123","DOIUrl":"https://doi.org/10.29001/2073-8552-2018-34-1-118-123","url":null,"abstract":"Aim. To analyze the changes in the aerobic-hemodynamic parameters during physical exercise in patients with effort angina administered with reference non-selective beta-blocker propranolol (Obsidan) with positive antianginal action and the absence of clinical effect after the drug intake.Material and Methods. A total of 58 patients (mean age of 54.2 [48.5; 59.5] years) with effort angina of functional class II–IV were examined with spiro-veloergometry tests before and after administration of propranolol (Obsidan: manufactured by Isis Pharma GmbH, Germany) at a dose of 40 mg. At threshold physical activity the following parameters were assessed: oxygen consumption (VO2 ), specific oxygen consumption, cardiac index (CI), rate pressure product (RPP); total peripheral vascular resistance (TPVR), arteriovenous oxygen difference (a-vDО2 ) and mechanical work of the heart (HW).Results. The efficacy of single-dose obsidian was observed in 58.6% of patients with angina (group 1); in this, tolerance to physical exercise increased from 50.0 [25.0; 75.0] W to 75.0 [50.0; 100.0] W. In the rest of patients (group 2), no antianginal effect was registered. At the first stage (at initial threshold physical activity level), administration of propranolol was characterized by saving pattern of heart function: statistically significant decrease in the heart rate, mean arterial pressure, CI and HW. This naturally resulted in reduction of myocardial oxygen demand (decrease in RPP from 163.0 [134.5; 218.5] U to 102.0 [90.0; 142.5] U; p<0.001) and predetermined the drug anti-ischemic action. At the second stage (maximum physical effort), an increase in the physical activity, caused by increase in VO2 from 738.0 [604.5; 1148.0] mL/min to 972.0 [774.5; 1458.0] mL/min, occurred due to higher oxygen extraction from peripheral blood (a-vDО2 increase; p<0.002). In group 2, despite the absence of an increase in tolerance to physical exercise, administration of propranolol was characterized by low RPP threshold i.e. the physical effort similar to the initial level was performed at a lower cardiac energy consumption.Conclusion. Therefore, anti-ischemic effect of Obsidan was due to a decrease in theenergy expenditure of the cardiac function along with a limitation in the hemodynamic productivity efficiently compensated by an increase in the oxygen extraction from circulating blood during physical activity.","PeriodicalId":153905,"journal":{"name":"The Siberian Medical Journal","volume":"125 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130799126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
MITRAL VALVE GEOMETRY IN HYPERTROPHIC CARDIOMYOPATHY AND ITS ROLE IN THE DEVELOPMENT OF LEFT VENTRICULAR OUTFLOW TRACT OBSTRUCTION 肥厚性心肌病的二尖瓣几何形状及其在左心室流出道梗阻发展中的作用
The Siberian Medical Journal Pub Date : 2019-04-23 DOI: 10.29001/2073-8552-2018-34-1-69-77
Ф. Канев, Е. Н. Павлюкова, A. Kanev, E. N. Pavlyukova, A. V. Evtushenko
{"title":"MITRAL VALVE GEOMETRY IN HYPERTROPHIC CARDIOMYOPATHY AND ITS ROLE IN THE DEVELOPMENT OF LEFT VENTRICULAR OUTFLOW TRACT OBSTRUCTION","authors":"Ф. Канев, Е. Н. Павлюкова, A. Kanev, E. N. Pavlyukova, A. V. Evtushenko","doi":"10.29001/2073-8552-2018-34-1-69-77","DOIUrl":"https://doi.org/10.29001/2073-8552-2018-34-1-69-77","url":null,"abstract":"Aim. To evaluate structural features of the mitral valve (MV) in patients with left ventricular hypertrophy (LVH) and to identify characteristics of MV structural remodeling in hypertrophic obstructive cardiomyopathy (HOCM) patients using three-dimensional MV quantification analysis.Material and Methods. The study included 48 patients with HOCM and 15 patients with arterial hypertension and LVH. All patients underwent standard echocardiography and real-time 3D transesophageal echocardiography, followed by MV reconstruction with quantitative analysis. Quantitative analysis of MV included assessment of the mitral annulus and cusps.Results. Differences in characteristics of three-dimensional MV model between patients with HOCM and arterial hypertension and LVH were identified. In patients with HOCM, the height of the fibrous ring of the MV was increased compared to that in patients with arterial hypertension (8.00±1.72 mm vs. 5.99±1.95 mm; p=0.02). Mitral annular height (r=-0.55; p=0.02) and area(3D) (r=-0.30; p=0.04) correlated with peak LV outflow tract (LVOT) gradient. MV nonplanarity index was higher in HOCM patients (2.37±0.47 units vs. 1.73±0.62 units; p=0.02). Mitral annular maximal velocity correlated with peak (r=0.48, p=0.002) and mean (r=0.47, p=0.01) LVOT gradients. Anterior (6.40±2.04 sm2 vs. 5.07±1.04 sm2 ; p<0.05) and posterior (6.61±2.01 см2 vs. 5.27±1.23 см2 ; p=0.006) cusp areas, total cusp area (13.01±3.54 sm2 vs. 10.34±1.82 sm2 ; p=0.008), and total cusp area to annular area ratio (1.31±0.2 units vs. 1.15±0.09 units; р=0.01) had higher values in patients with HOCM. Correlation existed between anterior leaflet length and peak LVOT gradient (r=-0.45; p=0.01). Patients with HOCM had increased anterior leaflet angle compared to patients with arterial hypertension and LVH (32.13±9.21° vs. 24.86±4.45°; р=0.04).Conclusion. Compared to patients with arterial hypertension and LVH, patients with HOCM experienced more pronounced MV annular remodeling presented as an increase in the annular height, which was accompanied by an increase in the cusp areas and the anterior leaflet angle. In patients with HOCM, the annular area and the maximum mitral annular velocity correlated with LVOT gradient.","PeriodicalId":153905,"journal":{"name":"The Siberian Medical Journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130849987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CAPABILITIES AND LIMITATIONS OF SPECKLE TRACKING STRESS ECHOCARDIOGRAPHY 斑点跟踪应力超声心动图的能力和局限性
The Siberian Medical Journal Pub Date : 2019-04-23 DOI: 10.29001/2073-8552-2018-34-1-10-17
A. Stepanova, M. Alekhin
{"title":"CAPABILITIES AND LIMITATIONS OF SPECKLE TRACKING STRESS ECHOCARDIOGRAPHY","authors":"A. Stepanova, M. Alekhin","doi":"10.29001/2073-8552-2018-34-1-10-17","DOIUrl":"https://doi.org/10.29001/2073-8552-2018-34-1-10-17","url":null,"abstract":"Stress echocardiography is a technique that allows to evaluate myocardial contractility and intracardiac hemodynamics under conditions of physical exercise or reaction to a pharmacological drug. Evaluation of systolic function of the left ventricle plays an important role in establishing the prognosis and choosing a treatment strategy for various cardiovascular diseases. Speckle tracking technique is one of the most promising methods for determining values of left ventricular deformation, due to which not only visual, but also quantitative assessment of left ventricular myocardial contractility is possible at rest and during stress tests. In this review, we analyzed the possibility of using speckle tracking stress echocardiography with physical exercise or with the pharmacological drug, in order to diagnose various diseases, such as ischemic heart disease, valvular heart disease, diabetes mellitus, and microvascular damage. Along with this, differences between the values of the longitudinal systolic deformation depending on age were considered. We also compared diagnostic values of the data of speckle-tracking stress echocardiography and coronary angiography and values of the data of speckle-tracking stress echocardiography and computed tomography of the coronary arteries.","PeriodicalId":153905,"journal":{"name":"The Siberian Medical Journal","volume":"23 17","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113984644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
EVALUATION OF REGIONAL CEREBRAL BLOOD FLOW BY SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IN THE EARLY POSTOPERATIVE PERIOD OF SIMULTANEOUS REVASCULARIZATION OPERATIONS IN PATIENTS WITH COMBINED ATHEROSCLEROTIC LESIONS OF THE CAROTID AND CORONARY ARTERIES 单光子发射计算机断层扫描评价颈动脉和冠状动脉合并动脉粥样硬化病变患者同时行血管重建术术后早期脑区域血流量
The Siberian Medical Journal Pub Date : 2019-04-23 DOI: 10.29001/2073-8552-2018-34-1-85-91
A. Korotkevich, S. Semenov, Y. Portnov, N. I. Milinevskiy
{"title":"EVALUATION OF REGIONAL CEREBRAL BLOOD FLOW BY SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY IN THE EARLY POSTOPERATIVE PERIOD OF SIMULTANEOUS REVASCULARIZATION OPERATIONS IN PATIENTS WITH COMBINED ATHEROSCLEROTIC LESIONS OF THE CAROTID AND CORONARY ARTERIES","authors":"A. Korotkevich, S. Semenov, Y. Portnov, N. I. Milinevskiy","doi":"10.29001/2073-8552-2018-34-1-85-91","DOIUrl":"https://doi.org/10.29001/2073-8552-2018-34-1-85-91","url":null,"abstract":"Aim. To evaluate the effect of simultaneous surgical intervention on regional cerebral blood flow (CBF) based on single photon emission computed tomography (SPECT).Material and Methods. The study included 14 patients with hemodynamically significant stenoses of the coronary and carotid arteries that underwent coronary artery bypass grafting concomitant with carotid endarterectomy. Brain SPECT with 99mTcHMPAO was performed twice: before surgery and in the postoperative period at days 5–7.Results. Overall, the group showed a statistically significant increase in regional cerebral blood flow in comparison with preoperative indicators in the area of the right caudate nucleus from 54.14±6.84 mL/100 g/min in the preoperative stage to 61.43±13.35 mL/100 g/min after surgery, p=0.037634, and in the left temporal lobe from 41.64±2.73 mL/100 g/min in the preoperative stage to 44.57±4.91 mL/100 g/min after surgery, p=0.019224. There were deviations of CBF less than 5 mL/100 g/min in 11 cases (79%) in most of the analyzed regions; the changes in cerebral blood flow were more pronounced in 3 cases: there was a diffuse increase in cerebral blood flow in 2 cases (14%) and а diffuse reduction of cerebral blood flow in 1 case (7%).Conclusion. Data obtained in a small sample of patients with combined atherosclerotic lesions of the carotid and coronary arteries preliminary suggest the absence of a statistically significant negative effect of simultaneous surgical intervention on the regional cerebral blood flow in all major basins of the cerebral arteries of the brain. Observed increase in the perfusion indices in the isolated analyzed zones, not exceeding 34%, may correspond to reactive benign postischemic hyperperfusion within the concept of reperfusion syndrome.","PeriodicalId":153905,"journal":{"name":"The Siberian Medical Journal","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122729713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LUNG ULTRASONOGRAPHY IN PNEUMONIA 肺炎的肺部超声检查
The Siberian Medical Journal Pub Date : 2019-04-23 DOI: 10.29001/2073-8552-2018-34-1-78-84
E. V. Chuyashenko, V. Zavadovskaya, T. S. Ageeva, N. M. Prosekina, M. Zorkaltsev, E. Fedorova
{"title":"LUNG ULTRASONOGRAPHY IN PNEUMONIA","authors":"E. V. Chuyashenko, V. Zavadovskaya, T. S. Ageeva, N. M. Prosekina, M. Zorkaltsev, E. Fedorova","doi":"10.29001/2073-8552-2018-34-1-78-84","DOIUrl":"https://doi.org/10.29001/2073-8552-2018-34-1-78-84","url":null,"abstract":"Aim. In order to optimize the diagnosis of pneumonia by including lung ultrasonography in the diagnostic algorithm for pneumonia, the main ultrasound signs of inflammatory infiltration of the lungs were identified, depending on the form of morphological substrate, and the capabilities of ultrasound examination in monitoring pneumonia were evaluated.Material and Methods. A total of 96 patients were admitted to hospital by emergency to rule out/to confirm pneumonia based on X-ray diagnosis of this pathology in 81 persons. Ultrasonic examination was performed in all patients at a day of admission to hospital. Dynamics in inflammatory infiltrate was evaluated in 55 patients at days 3–4, 7, and 10–14 of hospital stay.Results. The ultrasonic signs of inflammatory infiltrate were found in 55 of 96 patients with prevalent ultrasound pattern of pleuropneumonia (n=48; 50%) and bronchopneumonia in a smaller number of patients (n=7; 8.6%). The results of ultrasonography showed the low sensitivity (69.7%) and significantly high specificity (100%) rates of the method in detecting pneumonia. Positive dynamics in ultrasonic monitoring of pneumonia was detected in the overwhelming number of patients (n=45; 81.8%) at day 3 of hospitalization. Negative dynamics (n=3; 5.5%) was observed at days 3 and 7 of the study.Conclusion. Ultrasonic study may be considered a useful step in the diagnostic algorithm for patients with pneumonia as this method provides additional information for an attending physician and does not involve adverse effects of ionizing radiation on patient’s body. Since the ultrasonic data on positive and negative dynamics of pneumonia were received ahead of the results of standard control radiography and were verified by further clinical and radiological observations, the role of ultrasonic monitoring of the inflammatory infiltrate was essential for evaluation of the efficacy of antibiotic therapy at earlier time.","PeriodicalId":153905,"journal":{"name":"The Siberian Medical Journal","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134164580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FEATURES OF STRUCTURAL AND ELECTRICAL REMODELING OF THE HEART ASSOCIATED WITH HIGH RISK OF LIFETHREATENING VENTRICULAR TACHYARRHYTHMIAS IN PATIENTS WITH ISCHEMIC AND NON-ISCHEMIC CARDIOMYOPATHIES 缺血性和非缺血性心肌病患者与危及生命的室性心动过速高风险相关的心脏结构和电重构特征
The Siberian Medical Journal Pub Date : 2019-04-23 DOI: 10.29001/2073-8552-2018-34-1-39-47
O. Stukalova, A. A. Zhambeev, S. F. Sokolov, Oleg V. Sapelnikov, Igor R. Grishin, V. G. Kiktev, N. Shlevkov
{"title":"FEATURES OF STRUCTURAL AND ELECTRICAL REMODELING OF THE HEART ASSOCIATED WITH HIGH RISK OF LIFETHREATENING VENTRICULAR TACHYARRHYTHMIAS IN PATIENTS WITH ISCHEMIC AND NON-ISCHEMIC CARDIOMYOPATHIES","authors":"O. Stukalova, A. A. Zhambeev, S. F. Sokolov, Oleg V. Sapelnikov, Igor R. Grishin, V. G. Kiktev, N. Shlevkov","doi":"10.29001/2073-8552-2018-34-1-39-47","DOIUrl":"https://doi.org/10.29001/2073-8552-2018-34-1-39-47","url":null,"abstract":"Objective: to identify the features of myocardial fibrosis and ventricular repolarization disorders associated with malignant ventricular tachyarrhythmias (VT) in patients with ischemic (ICM) and non-ischemic cardiomyopathy (NICM).Material and Methods. Fifty consecutive patients (41 men and 9 women aged 60±13 years; 30 patients with ICM and 20 patients with NICM) underwent contrast magnetic resonance imaging (MRI) of the heart, QT dispersion analysis of 12-lead Holter ECG followed by implantation of cardioverter-defibrillator (ICD) or resynchronizing device with defibrillator (CRTD) to prevent sudden cardiac death.Results. According to data of 32 (28–43)-month follow up, VT paroxysms were registered in 20 of 30 patients (67%) with ICM and in 5 of 20 patients (25%) with NICM on follow-up. Data of successive univariate and ROC analyses of MRI indices differed between patients with and without recurrence of VTs in ICM and NICM patient groups. In ICM patients, VTs were associated with the values of QT (peak) interval dispersion over 80 mc according to data of Holter ECG monitoring and higher gray zone in the left ventricle (≥27%) according to contrast-enhanced MRI. Similar analyses in NICM patients showed that the most valuable diagnostic signs associated with the right ventricular tachycardias were the values of QT (peak) interval dispersion over 90 mc according to data of Holter ECG monitoring and the presence of non-transmural fibrosis of the left ventricle (≥27%) according to contrast-enhanced MRI.Conclusion. The features of structural remodeling of the left ventricle predisposing to VTs significantly differ in patients with ICM and NICM. Nevertheless, the presence of ventricular repolarization disorders, associated with onset of VTs, is universal in patients with ischemic and non-ischemic cardiomyopathies.","PeriodicalId":153905,"journal":{"name":"The Siberian Medical Journal","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115190872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MORPHOLOGICAL AND PERFUSION PREDICTORS OF DISTANT CEREBRAL DISORDERS IN CARDIAC SURGERY PATIENTS 心脏手术患者远端脑功能障碍的形态学和灌注预测因素
The Siberian Medical Journal Pub Date : 2019-04-23 DOI: 10.29001/2073-8552-2018-34-1-92-97
Y. Portnov, S. Semenov, I. Syrova, I. V. Sigitov
{"title":"MORPHOLOGICAL AND PERFUSION PREDICTORS OF DISTANT CEREBRAL DISORDERS IN CARDIAC SURGERY PATIENTS","authors":"Y. Portnov, S. Semenov, I. Syrova, I. V. Sigitov","doi":"10.29001/2073-8552-2018-34-1-92-97","DOIUrl":"https://doi.org/10.29001/2073-8552-2018-34-1-92-97","url":null,"abstract":"Aim. To assess the preoperative morphological state of the brain and the state of cerebral circulation in patients referred for coronary bypass surgery to identify predictors of long-term cerebral disorders.Material and Methods. The study included 33 male patients, divided into 2 groups according to the presence or the absence of distant neurological complications 5 years after surgery. All patients underwent non-contrast computed tomography of the brain and perfusion computed tomography. Computed tomography was repeated 5 years after surgery.Results. The perfusion indices in all measurement zones in patients of the two groups did not significantly differ. Significant differences in width of the third ventricle and ventricular-cranial index between patients of groups 1 and 2 were not identified. The incidence rates of leukoaraiosis significantly differed: leukoaraiosis was detected significantly more frequently in group 2 (78% of cases) than in patients of group 1 (31%), p=0.0455.Discussion. The dimensions of the brain cavity system and the preoperative state of the microcirculatory blood flow were not predictors of long-term postoperative neurological disorders. Five years after surgery, patients of group 2 showed clinical and morphological signs of past ischemic changes, which were not detected in patients of group 1 suggesting that leukoaraiosis was an unfavorable prognostic indicator of postoperative cerebrovascular disorders in the long-term period.Conclusion. When referring a patient with the presence of morphological manifestations of cerebral microangiopathy in the form of the leukoaraiosis phenomenon for cardiac surgery, these patients should be considered at risk requiring administration of the necessary set of measures for the prevention of long-term cerebral disorders.","PeriodicalId":153905,"journal":{"name":"The Siberian Medical Journal","volume":"88 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127029901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DIAGNOSIS AND EMERGENCY SURGICAL TREATMENT OF GIANT LEFT ATRIAL SARCOMA: CLINICAL CASES 巨大左心房肉瘤的诊断与急诊手术治疗:临床病例
The Siberian Medical Journal Pub Date : 2019-04-23 DOI: 10.29001/2073-8552-2018-34-1-130-136
В. Еремина, А. В. Молочков, М. Н. Алехин, G. E. Gogin, Natalya V. Eremina, A. V. Molochkov, Mikhail N. Alekhin
{"title":"DIAGNOSIS AND EMERGENCY SURGICAL TREATMENT OF GIANT LEFT ATRIAL SARCOMA: CLINICAL CASES","authors":"В. Еремина, А. В. Молочков, М. Н. Алехин, G. E. Gogin, Natalya V. Eremina, A. V. Molochkov, Mikhail N. Alekhin","doi":"10.29001/2073-8552-2018-34-1-130-136","DOIUrl":"https://doi.org/10.29001/2073-8552-2018-34-1-130-136","url":null,"abstract":"We present two clinical cases of the late primary diagnosis of cardiac sarcoma with an unusual intracavitary growth in the left atrium with the left atrioventricular orifice obstruction requiring an emergency surgical intervention. A variety of concomitant clinical symptoms that mask the underlying pathological process and impede differential diagnosis has been described.","PeriodicalId":153905,"journal":{"name":"The Siberian Medical Journal","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126251315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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