临床和实验医学杂志最新文献_第5页

Difficulties in diagnosis of carcinoma of the tongue 舌癌诊断的困难

临床和实验医学杂志 Pub Date : 2020-01-01 DOI: 10.15584/ejcem.2019.4.14

D. Panda, Bhubaneswar Odisha India Acharya Vihar

引用次数: 0

Effects of sensory integration therapy in a 7-year old child with epilepsy following craniocerebral trauma – a case study 感觉统合治疗对7岁儿童颅脑外伤后癫痫的疗效研究

临床和实验医学杂志 Pub Date : 2020-01-01 DOI: 10.15584/ejcem.2020.1.15

Maria Widelak, A. Wolan-Nieroda, J. Podgórska-Bednarz, A. Guzik

引用次数: 0

Applicability of Cardiopulmonary Exercise Test 心肺运动试验的适用性

临床和实验医学杂志 Pub Date : 2020-01-01 DOI: 10.15584/ejcem.2019.4.11

Filip Wołoszyn, P. Pańczyszyn-Trzewik, Seweryn Ziajor, Aleksandra Misygar, Artur Bednarski, Oskar Kwiatkowski, M. Sowa-Kućma

引用次数: 1

Seroprevalence of Toxoplasmosis among Human Immunodeficiency Virus infected pregnant women in Abuja Teaching Hospital, Nigeria 尼日利亚阿布贾教学医院感染人类免疫缺陷病毒的孕妇中弓形虫病的血清患病率

临床和实验医学杂志 Pub Date : 2020-01-01 DOI: 10.15584/ejcem.2020.3.3

M. Zakari, A. Isah, R. Offiong, T. Yunusa, I. Abdullahi

引用次数: 1

Cognitive behavioural therapy and core stabilization exercise on pain-related disability and psychological status in patients with non-specific chronic low back pain 认知行为疗法和核心稳定运动对非特异性慢性腰痛患者疼痛相关残疾和心理状态的影响

临床和实验医学杂志 Pub Date : 2020-01-01 DOI: 10.15584/ejcem.2020.3.6

A. Akodu, T. Ogunbiyi, O. Fapojuwo

{"title":"Cognitive behavioural therapy and core stabilization exercise on pain-related disability and psychological status in patients with non-specific chronic low back pain","authors":"A. Akodu, T. Ogunbiyi, O. Fapojuwo","doi":"10.15584/ejcem.2020.3.6","DOIUrl":"https://doi.org/10.15584/ejcem.2020.3.6","url":null,"abstract":"Introduction. Exercises have been shown to relieve symptoms in non-specific chronic low back pain (NSCLBP) patients. Aim. This study compared the effects of cognitive behavioural therapy (CBT) and core stabilization exercises (CSE) on pain-related disability, psychological status and sleep disturbance in patients with NSCLBP. Material and methods. This randomized controlled trial involved a total of thirty-seven (37) participants. They were randomly allotted into three groups [CBT (11), CSE (14) and control (12)]. The intervention was done once per week for duration of 60 minutes for the CBT group, 30 minutes for CSE group and 10 minutes for the control group twice per week for 8 consecutive weeks. Assessment of outcome was done at baseline, 4 weeks and 8 weeks. Data were analyzed using statistical package for social science version 25 at alpha level of less than 0.05. Results. The results of this study showed that there was significant improvement in the level of pain-related disability (p= 0.001), level of anxiety (p =0.001), depression (p = 0.01, p = 0.001, p =0.001) and sleep disturbance (p = 0.001) in all the groups (CBT, CSE, control) post treatment. Conclusion. CBT and CSE are both effective in the treatment of pain-related disability, sleep disturbance, and psychological status of NSCLBP patients.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75104695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Laparoscopic partial cystectomy for bladder endometriosis – case report 腹腔镜膀胱部分切除术治疗膀胱子宫内膜异位症1例报告

临床和实验医学杂志 Pub Date : 2020-01-01 DOI: 10.15584/ejcem.2019.4.13

D. Godlewski, Patryk Pszczółkowski, T. Góra, Łukasz Futyma, T. Fedus, D. Aebisher

引用次数: 0

Genetic study of a family with affected members with Waardenburg syndrome type 4 without Hirschsprung disease 无巨结肠疾病的Waardenburg综合征4型患者家族遗传研究

临床和实验医学杂志 Pub Date : 2020-01-01 DOI: 10.15584/ejcem.2020.2.3

Mitra Sabetghadam Moghadam, Sima Rayat, S. Morovvati

{"title":"Genetic study of a family with affected members with Waardenburg syndrome type 4 without Hirschsprung disease","authors":"Mitra Sabetghadam Moghadam, Sima Rayat, S. Morovvati","doi":"10.15584/ejcem.2020.2.3","DOIUrl":"https://doi.org/10.15584/ejcem.2020.2.3","url":null,"abstract":"Introduction. Waardenburg syndrome (WS) is an autosomally inherited disorder with the most common state compounding pigmentary abnormality and sensorineural deafness. The rarest type of the disease is WS4 with the general characteristic discriminated from other types by the attendance of Hirschsprung disease (HD). Among the several genes, one of the causative genes in WS4 is endothelin 3 (EDN3) with both autosomal recessive and dominant inheritance. Aim. The intention of the present study is to report a pathogenic mutation as the genetic cause of WS in an Iranian family with four patients without any segregation criteria for the type of the disease. Material and methods. In order to detect of causing gene or genes related to the disease, Whole exome sequencing (WES) technique in proband’s sample was done. To confirm the detected mutation in proband and some family members with or without the disease direct sequencing of END3 gene was performed using Sanger method. Results. Pedigree analysis suggested segregation of WS as an autosomal recessive trait in the family. WES analysis suggested a gene (EDN3) related to WS type 4B. DNA sequencing confirmed a pathogenic missense mutation c.293C>T, p.T98M in EDN3 gene in all of the four patients. Conclusion. Determination of WS can usually be missed owing to the lack of some attributes in every sufferer and also conventional clinical variance, in spite of several affected members in a single family. So, Genetic counseling is pivotal for families with multiple members influenced. We detected c.293C>T, p.T98K mutation in EDN3 gene as a pathogenic variant which has been known as a likely pathogenic state in the American College of Medical Genetics and Genomics (ACMG) guidelines, despite one prior report. It will be helpful in genetic diagnosis of affected persons and increases the mutation spectrum of EDN3 gene.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82357437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastro-esophageal reflux and obstructive sleep apnea – is there a link? 胃食管反流和阻塞性睡眠呼吸暂停——有联系吗?

临床和实验医学杂志 Pub Date : 2020-01-01 DOI: 10.15584/ejcem.2020.2.5

Piotr Pardak, A. Pękala, S. Jarmakiewicz, R. Filip

{"title":"Gastro-esophageal reflux and obstructive sleep apnea – is there a link?","authors":"Piotr Pardak, A. Pękala, S. Jarmakiewicz, R. Filip","doi":"10.15584/ejcem.2020.2.5","DOIUrl":"https://doi.org/10.15584/ejcem.2020.2.5","url":null,"abstract":"Introduction. The epidemic of obesity has led to an increase in the occurrence of obstructive sleep apnea and gastro-esophageal reflux disease. The mechanism of development of gastro-esophageal reflux disease is multifactorial, and studies conducted in the last decade have shed new light on the causes of its development in patients with sleep apnea and obesity. Aim. The aim of the study was to discuss the mechanism of development of gastro-esophageal reflux disease is multifactorial, and studies conducted in the last decade have shed new light on the causes of its development in patients with sleep apnea and obesity and the dysfunction of the lower esophageal sphincter. Material and methods. An analysis of literature regarding gastro-esophageal reflux and obstructive sleep apnea. Results. In obstructive sleep apnea and obesity, high levels of cytokines and insulin resistance are observed, resulting in disorders in the levels of ghrelin – a hormone responsible for normal gastrointestinal motility. Conclusion. The effect of deviations in the ghrelin profile on the development of gastro-esophageal reflux disease remains a matter for further research.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87681504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

External ophthalmomyiasis by sheep botfly – a report from Sirmaur hills 羊蝇引起的外眼病——一份来自锡马尔山的报告

临床和实验医学杂志 Pub Date : 2020-01-01 DOI: 10.15584/ejcem.2020.1.14

A. Chauhan, N. Gautam

引用次数: 0

Treating kidney cancer – a review 治疗肾癌——综述

临床和实验医学杂志 Pub Date : 2020-01-01 DOI: 10.15584/ejcem.2020.1.8

Piotr Przyczyna, D. Aebisher, D. Bartusik-Aebisher, E. Kaznowska

引用次数: 0