临床和实验医学杂志最新文献_第10页

Retrospective analysis of reactive hyperplastic lesions in the oral cavity 口腔反应性增生性病变的回顾性分析

临床和实验医学杂志 Pub Date : 2018-01-01 DOI: 10.15584/EJCEM.2018.2.2

Justyna Farynowska, K. Błochowiak, D. Trzybulska, M. Wyganowska-Swiatkowska

{"title":"Retrospective analysis of reactive hyperplastic lesions in the oral cavity","authors":"Justyna Farynowska, K. Błochowiak, D. Trzybulska, M. Wyganowska-Swiatkowska","doi":"10.15584/EJCEM.2018.2.2","DOIUrl":"https://doi.org/10.15584/EJCEM.2018.2.2","url":null,"abstract":"Introduction. Reactive hyperplastic lesions of the oral cavity are non-neoplastic lesions that result from low-grade chronic irritation of the oral mucosa. Objectives. The aim of this study was to present the epidemiological characteristics of reactive lesions. Materials and methods. The study was a retrospective analysis of the medical records of 116 patients with reactive lesions. The tissue specimens were obtained by biopsy. 115 patients underwent an excisional biopsy, whereas in one case an incisional biopsy was performed. Results. The most frequently encountered lesion was inflammatory fibrous hyperplasia (IFH) (n=37, 31.9%), followed by irritation fibroma (IF) (n=36, 31%), pyogenic granuloma (PG) (n=15, 12.9%), fissured granuloma (FG) (n= 14, 12.1%). The lesions were more commonly observed in females (n=70, 60.3%) than in males (n=46, 39.7%) with a ratio of 1.5:1, respectively. The buccal and labial mucosa were the most prevalent sites of reactive lesions. Most of the lesions were between >5 mm and ≤10 mm in diameter except for FGs, which were much bigger. Conclusions. Early detection and elimination of all potentially causative factors and irritants is a crucial matter, especially in the case of the vestibule of the oral cavity, which is the most susceptible area of the oral cavity.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82192252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Influence of Adriblastin and Bleomycin on Wistar rat mothers and fetus development 阿霉素和博来霉素对Wistar大鼠母胎发育的影响

临床和实验医学杂志 Pub Date : 2018-01-01 DOI: 10.15584/ejcem.2018.2.1

Anna Sęk-Mastej, Sabina Galiniak, Izabela Krawczyk-Marć, Krzysztof Balawender, Artur Szymczak, M. Kaniewski, Natalia Leksa, Marek Biesiadecki, S. Orkisz

{"title":"Influence of Adriblastin and Bleomycin on Wistar rat mothers and fetus development","authors":"Anna Sęk-Mastej, Sabina Galiniak, Izabela Krawczyk-Marć, Krzysztof Balawender, Artur Szymczak, M. Kaniewski, Natalia Leksa, Marek Biesiadecki, S. Orkisz","doi":"10.15584/ejcem.2018.2.1","DOIUrl":"https://doi.org/10.15584/ejcem.2018.2.1","url":null,"abstract":"Introduction. Gestation is a very sensitive time both to mother and child. Any substance, factor, or environmental condition disturbing homeostasis may cause congenital defects, anomalies or even death. Teratology evaluates those potential factors and their influence. Also, medicinal products used during pregnancy may be teratogenic. Adriblastin, also known as Doxorubicin, and Bleomycin are widely used cytostatic drugs in oncology. Aim. Aim of this study was to evaluate the embryotoxic effects of Doxorubicin and Bleomycin in an animal model. Materials and methods. Fertilised Wistar rat females were given each drug intraperitoneally between the 8th and 15th gestation day, and compared to control group receiving placebo (distilled water, 0.9% NaCl). Another group received acetyl salicylic acid, as a model, well known teratogen. Changes in mothers’ weight from baseline, implantation of embryos, any discrepancies in mothers wombs and health as well as defects in fetuses were evaluated and compared. Fetus skeletons were stained by Dowson’s method to visualise bone defects. Results and conclusion. Both Adriblastin and Bleomycin were teratogenic, producing significantly more embryo absorptions, and fetal defects compared to placebo. The effects of the two cytostatics were similar to the model teratogen acetyl salicylic acid.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79090334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ramsay Hunt syndrome with deep hearing loss and meningitis 拉姆齐·亨特综合症伴有深度听力丧失和脑膜炎

临床和实验医学杂志 Pub Date : 2018-01-01 DOI: 10.15584/EJCEM.2018.1.10

K. Błochowiak, B. Kamiński

引用次数: 1

Additive interaction for three-drug combination of carbamazepine, lacosamide and lamotrigine against maximal electroshock-induced seizures – a type I isobolographic analysis 卡马西平、拉科沙胺和拉莫三嗪三药联合抗最大电休克诱发癫痫发作的加性相互作用- I型等密度分析

临床和实验医学杂志 Pub Date : 2018-01-01 DOI: 10.15584/EJCEM.2017.4.1

Maria Kondrat-Wróbel, J. Łuszczki

{"title":"Additive interaction for three-drug combination of carbamazepine, lacosamide and lamotrigine against maximal electroshock-induced seizures – a type I isobolographic analysis","authors":"Maria Kondrat-Wróbel, J. Łuszczki","doi":"10.15584/EJCEM.2017.4.1","DOIUrl":"https://doi.org/10.15584/EJCEM.2017.4.1","url":null,"abstract":"Introduction. Treatment of epilepsy patients with one antiepileptic drug often fails and then the insufficiently medicated patients need two or three antiepileptic drugs combined together to stop their seizures. However, polytherapy is always associated with drug-drug interactions whose nature may or may not be favorable for epilepsy patients. Preclinical studies on animals can help to select beneficial combinations of antiepileptic drugs that could be used in further clinical settings. Aim. To isobolographically characterize anticonvulsant effects of a combination of three antiepileptic drugs (carbamazepine, lacosamide and lamotrigine) at the fixed drug dose ratio of 1:1:1 in the mouse maximal electroshock-induced seizure test. Material and methods. Maximal electroconvulsions were evoked in male Swiss mice by a current (25 mA, 500 V, 0.2 s stimulus duration) delivered via auricular electrodes. Type I isobolographic analysis was applied to assess the interaction among carbamazepine, lacosamide and lamotrigine. Results. Isobolographic analysis revealed that the combination of carbamazepine, lacosamide and lamotrigine produced additive interaction in the mouse maximal electroshock-induced seizure test. Conclusions. Additivity among carbamazepine, lacosamide and lamotrigine in this preclinical study can be translated to clinical settings and this three-drug combination can be recommended as a treatment option for epilepsy patients who are resistant to standard treatment regimens.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89969063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Summary of Research Progress of Brain Machine Integration 脑机集成研究进展综述

临床和实验医学杂志 Pub Date : 2018-01-01 DOI: 10.29422/JOCEM.201812_2(4).0001

Li-juan Su

引用次数: 0

Patient’s satisfaction with anesthesia based on the polish version of the of Iowa Satisfaction with Anesthesia Scale. Satisfaction with anesthesia in patients with craniofacial trauma 采用改良版爱荷华麻醉满意度量表评价患者的麻醉满意度。颅面外伤患者麻醉满意度分析

临床和实验医学杂志 Pub Date : 2018-01-01 DOI: 10.15584/EJCEM.2017.3.6

Dorota Ozga, D. Dyk, A. Gutysz-Wojnicka, M. Wojtaszek, W. Mędrzycka-Dąbrowska, O. Mazury

引用次数: 1

The comorbidity of papillary thyroid carcinoma and the primary hyperparathyroidism 甲状腺乳头状癌与原发性甲状旁腺功能亢进的合并症

临床和实验医学杂志 Pub Date : 2018-01-01 DOI: 10.15584/ejcem.2018.2.4

R. Podlasek, Grzegorz Bednarczyk, G. Świder

引用次数: 0

Review of surgical techniques for the reconstruction of the maxillofacial region used in the Department of Maxillo-Facial Surgery in Rzeszów Rzeszów颌面外科颌面部区域重建手术技术综述

临床和实验医学杂志 Pub Date : 2018-01-01 DOI: 10.15584/ejcem.2017.3.12

J. Frańczak, Paweł Pakla, R. Brodowski, W. Stopyra, Danuta Burdzy, B. Lewandowski

引用次数: 0

Nutritional behavior of pregnant women from the Podkarpacie province Podkarpacie省孕妇的营养行为

临床和实验医学杂志 Pub Date : 2018-01-01 DOI: 10.15584/EJCEM.2017.4.4

Katarzyna Dereń, M. Gawel, E. Łuszczki, S. Jarmakiewicz, A. Sokal, E. Polak, J. Wyszyńska

{"title":"Nutritional behavior of pregnant women from the Podkarpacie province","authors":"Katarzyna Dereń, M. Gawel, E. Łuszczki, S. Jarmakiewicz, A. Sokal, E. Polak, J. Wyszyńska","doi":"10.15584/EJCEM.2017.4.4","DOIUrl":"https://doi.org/10.15584/EJCEM.2017.4.4","url":null,"abstract":"Introduction. Healthy nutrition is very important during pregnancy for both a baby and a mother. Modification of metabolic and hormonal processes i.e. metabolic programming occurs already at the prenatal stage. This process significantly affects the baby’s health and eating habits at a later age. The diet of a pregnant woman should supplement the demand for energy, nutrients, vitamins and minerals. An expecting woman needs to also avoid products that are contraindicated during this period, such as raw milk, eggs or meat. Aim. Assessment of nutritional behavior of pregnant women from the Podkarpacie province. Materials and method. 228 women living in the Podkarpackie province were enrolled in the study. Surveys were collected via the Internet. An anonymous questionnaire developed by the authors was used. Results. Women’s eating habits are primarily influenced by education. Most women had knowledge about proper nutrition and awareness of its impact on the health of the baby. A worrying fact was a very low intake of dairy products. 44% of women consumed dairy products only once a day. Fruit and vegetables consumption was also low (40% of the respondents ate only from 100 to 200 g during the day). Conclusions. Although part of the eating habits of pregnant women is correct, nutritional education should be introduced in this group, especially related to the adequate supply of dairy products, fruit and vegetables to supplement the necessary vitamins, minerals and protein.","PeriodicalId":15378,"journal":{"name":"临床和实验医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88393962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Analysis of the correlation between body composition, construction and aerobic capacity in teenage team sport training 青少年团体运动训练中身体成分、结构与有氧能力的相关性分析

临床和实验医学杂志 Pub Date : 2018-01-01 DOI: 10.15584/EJCEM.2018.2.5

P. Matłosz, J. Michalowska, Grzegorz Sarnik, Jarosław Herbert, K. Przednowek, R. Grzywacz, E. Polak

引用次数: 1