Journal of Clinical and Experimental Dentistry最新文献

{"title":"Management of a clinical case of caries lesions by undergraduate dentistry students.","authors":"Sebastiana Arroyo-Bote, Aina Antonelli-Sastre","doi":"10.4317/jced.61889","DOIUrl":"https://doi.org/10.4317/jced.61889","url":null,"abstract":"<p><strong>Background: </strong>Dental caries remains the most prevalent chronic disease worldwide. Hence the importance of detecting and evaluating caries and combining this with additional diagnostic methods to ensure the best treatment. The main objective was to study what is the sensitivity and specificity for detecting initial and cavitated caries lesions by students in third, fourth and fifth year of the Degree in Dentistry at the University of Barcelona, analysing if there is any difference between the diagnoses and treatments among the different years and each student's clinical experience. It was also determined if they apply the techniques based on the concepts of minimal intervention.</p><p><strong>Material and methods: </strong>An observational cross-sectional study using an online survey was performed, based on a real clinical case, aimed at the students in third, fourth and fifth year of the Degree in Dentistry at the University of Barcelona.</p><p><strong>Results: </strong>Most of the respondents (72.13%) observed demineralization or cavities caused by caries in the clinical image and all in the radiographic image (100%). Meanwhile, they showed a more conservative attitude in the treatment of occlusal face, where 23.08% in 4.6 and 46.25% in 4.7 indicate filling of pits and fissures. On the other hand, on the proximal faces, they directly opted for a class II filling (95% in 4.5 distal, 94% in 4.6 mesial and 84% in 4.6 distal). Eighty-five percent of the students considered applying techniques based on the concepts of minimal intervention.</p><p><strong>Conclusions: </strong>The students use similar criteria when diagnosing and treating possible caries lesions regardless of academic year or clinical experience. The personal evaluation of the application of the concepts of minimal intervention does not correlate with the clinical attitude to those cases. <b>Key words:</b>Dental caries, caries diagnosis, caries management, questionnaire.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"16 12","pages":"e1433-e1444"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mesenchymal stem cell therapies evidence in the treatment of irradiated salivary glands: A scoping review.","authors":"Maria Stella Moreira, Maria Emília Mota, Suely Kunimi Kubo Ariga, Graziella Chagas Jaguar, Márcia Martins Marques","doi":"10.4317/jced.62242","DOIUrl":"https://doi.org/10.4317/jced.62242","url":null,"abstract":"<p><strong>Background: </strong>Radiotherapy is one of the main treatments for head and neck cancer; however, due to its non-selectivity the glandular tissue can be affected. This scoping review aimed to identify the evidence about mesenchymal stem cell therapies for irradiated salivary gland regeneration.</p><p><strong>Material and methods: </strong>Two independent reviewers performed a literature search in MEDLINE/PubMed, Scopus, and Web of Science. The inclusion criteria were: 1) studies evaluation regeneration of irradiated salivary glands by stem cell therapies (cell-based or cell-free), (2) <i>in vivo</i> studies.</p><p><strong>Results: </strong>The search resulted in 13 included studies. In general, both therapies demonstrated increased salivary levels, with mucin and amylase increased and structural protection of acinar cells. The cell-free therapy based on labial glands stem cell extract demonstrated a higher number of parasympathetic nerves.</p><p><strong>Conclusions: </strong>Stem cell therapies (cell-free and cell-based) appear promising strategies for recovering saliva production in patients presenting irradiation-induced hyposalivation, with positive results toward regeneration of the form and function of the glands. However, due to the scarcity and heterogenicity of these pre-clinical studies, it is not possible to indicate which is the more indicated therapy. <b>Key words:</b>Mesenchymal stem cells, extracellular vesicles, exosomes, salivary glands, stem cell biology, hyposalivation, radiotherapy.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"16 12","pages":"e1547-e1554"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Whitening: is Omnichroma universal composite unchanging? Spectrophotometric evaluation.","authors":"Francesca Zotti, Francesca Ferrari, Luciano Malchiodi, Carlotta Dorigatti, Francesca Pilati, Giorgia Lanzaretti, Nicoletta Zerman","doi":"10.4317/jced.62204","DOIUrl":"https://doi.org/10.4317/jced.62204","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate the color stability of Class V anterior restorations with universal composite after professional bleaching using a spectrophotometer.</p><p><strong>Material and methods: </strong>Class V cavities were prepared and restored with universal composite in twenty-eight extracted anterior teeth. One week after restoration, color analysis was performed using the spectrophotometer. In-office bleaching was performed. Color analysis was performed 24 hours, 72 hours and 30 days after bleaching. The parameters evaluated were L* values of each tooth and ΔE values between tooth and restoration at different timepoints. Data were analyzed using a statistical software. A P-value ≤0.05 was used to indicate statistical significance of the results.</p><p><strong>Results: </strong>There was a non-statistically significant but noticeable difference between the L* values in term of tooth bleaching effect. Non-statistically significant differences were found between the L* values and the ΔE values at different timepoints when evaluating the chromatic difference between the tooth surface and the restoration. The ΔE value one week after the restoration is higher than the ΔE values at the following timepoints, therefore the color difference between the restoration and the adjacent tooth decreases with time after bleaching.</p><p><strong>Conclusions: </strong>Universal Composite was found to be able to match the color of the surrounding tooth even after the bleaching procedure. <b>Key words:</b>Omnichroma, composite, color, spectrophotometer, whitening.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"16 12","pages":"e1459-e1467"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical-related Morphological Characteristics of Sphenoid Sinuses: A Comprehensive CT-Based Analysis.","authors":"Diego Santiago de Mendonça, Nadya Imani Newman, João Edson Ribeiro Leite, Esther Carneiro Ribeiro, Marcela Lima Gurgel, Cauby Maia Chaves Júnior, Lucia Helena Soares Cevidanes, Lúcio Mitsuo Kurita, Paulo Goberlânio de Barros Silva, Fábio Wildson Gurgel Costa","doi":"10.4317/jced.62099","DOIUrl":"10.4317/jced.62099","url":null,"abstract":"<p><strong>Background: </strong>This study aims to assess the relationships between sphenoid sinus (SS) types, septation, lobulation, symmetry, septal deviation, and the variations in SS pneumatization regarding the surrounding neurovascular structures using Computed tomography (CT) images. Sexes and age groups were investigated.</p><p><strong>Material and methods: </strong>We retrospectively evaluated head CT-scans of 320 patients (age range 18-49 years); mean of 43.13 ± 17.39 to evaluate the morphological characteristics of the SS (Symmetry, Pneumatization, Extension, Septation, Lobulation, Internal Carotid, and Optic Nerve). Analyses were performed using SPSS version 20.0 (IBM Corporation, Armonk, NY, USA), with a 95% confidence level.</p><p><strong>Results: </strong>Our findings revealed an incidence of anatomographical variations in terms of pneumatization that varied between 0.3% (conchal)-60% (postsellar). These variants include 72.5% subdorsal extension, 92.2% lobular extension. Septations either presented as complete septa (90.9%) which extend from the anterior to the posterior wall dividing the sinus into different antra or as incomplete accessory septa. We also demonstrated anatomographic variants in terms of Internal Carotid (ICA), and Optic Nerve (ON). As sphenoid sinuses pneumatize more, the frequency of optic nerve (ON) and internal carotid artery (ICA) protrusion and wall dehiscence into the sinus increases.</p><p><strong>Conclusions: </strong>Results show that anatomic variations and pneumatization of the paranasal sinuses holds significant importance in diagnosing and understanding sinus pathologies The findings underscore a potential correlation between the anatomical variants of the SS and the presence of population group variability. <b>Key words:</b>Sphenoid sinus, CT scan, •Sellar type, Internal carotid artery, Optic nerve.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"16 12","pages":"e1445-e1453"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of different root canal irrigations on the accuracy of apex locators: A systematic review.","authors":"Seyede Aye Shekarbaghani, Behnam Bolhari, Zohreh Khalilak","doi":"10.4317/jced.62049","DOIUrl":"10.4317/jced.62049","url":null,"abstract":"<p><strong>Background: </strong>For a successful root canal treatment, it is necessary to determine the correct working length. One of the most used tools to determine the length is: radiography and apex locator. The accuracy of APEX locator of different generations depends on various factors. Studies have reported various effects of root canal irrigations on Apex Locator accuracy. This review study collects the results of studies conducted in recent years so that dentists and specialists can choose the most appropriate root canal irrigation's protocol with the least negative impact on the accuracy of Apex Locator.</p><p><strong>Material and methods: </strong>This review article has been done in the form of a wide search in electronic databases such as MEDLINE, PubMed, BVS (Lilacs and BBO), Scopus, Web of Science, Cochrane Library and Embase in the period of 2010-2023. No language restrictions have been considered and the reference list of all related articles has been checked.</p><p><strong>Results: </strong>Out of 605 found articles, After removing duplicates and an initial screening, the full texts of only 25 articles are analyed and only 21 articles matched our inclusion criteria and their quality was assessed using modified CONSORT. This article is written based on the Preferred Reporting Items for Systematic Reviews and Meta‑Analyses protocol protocol. Based on the obtained results, use of hypochlorite alone, which has a negative effect on the accuracy of the apex locator due to its high electroconductivity.</p><p><strong>Conclusions: </strong>Use of a irrigation's protocol such as the use of 17% Ethylenediaminetetraacetic acid (EDTA) after sodium hypochlorite or chlorhexidine (CHX) or 0.1% octinidine dohydrochloride (OCT) is suggested compared to the use of sodium hypochlorite alone. <b>Key words:</b>Apex locator, irrigation solutions, sodium hypochlorite, Chlorhexidine, working length.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"16 12","pages":"e1538-e1546"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated hypoglossia: Oromandibular Limb Hypogenesis Syndrome Type 1 A - A Rare Case Report.","authors":"Manish Jha, Pooja Singh, Anusree Paul, Gopal Chandra Bera","doi":"10.4317/jced.62077","DOIUrl":"https://doi.org/10.4317/jced.62077","url":null,"abstract":"<p><p>Hypoglossia is a rare developmental anomaly of tongue. It is usually associated with various syndromes and other anomalies. Most common association of hypoglossia is with limb deformity and these disorders are collectively grouped as Oro Mandibular Limb Hypogenesis (OLHS) Syndrome. It represents a spectrum of disorders and cases with deviation from the original classification has been reported. Isolated hypoglossia without limb deformity is very rare and has been classified as OLHS Type 1 A by Hall. Features associated with this disorder is hypoplastic mandible, absence of mandibular incisors, intra oral bands and marked enlargement of sublingual muscular ridges and glands. This article reports a case of 22 years old female patient with isolated hypoglossia. Patient reported with the chief complain of irregularly placed teeth. Extra oral finding revealed a convex profile with retrognathic mandible. Intraoral examination revealed crowding in teeth with a constricted maxillary and mandibular arch. A small rudimentary tongue with reduced range of movement was seen. However no abnormalities of the extremities was seen. <b>Key words:</b>Hanhart syndrome, Hypoplastic mandible, Oligodontia, Small tongue.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"16 12","pages":"e1564-e1567"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival of teeth with external cervical resorption after Internal and External Repair: A Systematic Review.","authors":"Juliana Sousa, Ana Beatriz Azevêdo, Rebeka Santos, Michelle Silva, Zilda Farias, Ana Paula Sobral","doi":"10.4317/jced.62050","DOIUrl":"https://doi.org/10.4317/jced.62050","url":null,"abstract":"<p><strong>Background: </strong>To analyze the survival rate of teeth affected by invasive cervical resorption after internal and external repair.</p><p><strong>Material and methods: </strong>A search was conducted in PubMed/Medline, Web of Science, Embase, Scopus, the Cochrane Library, and gray literature at the DANS Easy Archive until September 2023. The selected studies were subjected to risk assessment of bias, and the quality of evidence was assessed using the Newcastle Ottawa Scale. The GRADE was used to analyze the certainty of evidence.</p><p><strong>Results: </strong>Three articles were included in this study. The Heithersay classification was used in all included studies. Only one study has reported on the Patel classification. Different results associated with the survival of treated invasive cervical resorption elements have been reported. Two studies reported a higher survival rate in externally repaired teeth than in internally repaired teeth. Only one study reported greater survival of theeth with external cervical resorption rate in the treatment with internal repair. The studies showed strong evidence and the certainty of the evidence was classified as very low.</p><p><strong>Conclusions: </strong>Failure rates were low in dental treatments with invasive cervical resorption for both repairs, with external repair being more promising and showing the highest survival rate in the follow-up period of at least one year. <b>Key words:</b>External cervical resorption, external repair, interal repair, survival rate, dental treatments.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"16 12","pages":"e1555-e1563"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Graph Neural Networks-Based Prediction of Drug Gene Interactions of RTK-VEGF4 Receptor Family in Periodontal Regeneration.","authors":"Pradeep Kumar Yadalam, Francisco T Barbosa, Prabhu Manickam Natarajan, Carlos M Ardila","doi":"10.4317/jced.61880","DOIUrl":"https://doi.org/10.4317/jced.61880","url":null,"abstract":"<p><strong>Background: </strong>The RTK-VEGF4 receptor family, which includes VEGFR-1, VEGFR-2, and VEGFR-3, plays a crucial role in tissue regeneration by promoting angiogenesis, the formation of new blood vessels, and recruiting stem cells and immune cells. Machine learning, particularly graph neural networks (GNNs), has shown high accuracy in predicting these interactions. This study aims to predict drug-gene interactions of the RTK-VEGF4 receptor family in periodontal regeneration using graph neural networks.</p><p><strong>Material and methods: </strong>The study utilized a dataset comprising 19,154 drug-gene interactions to analyze the relationships between drugs and protein-coding genes. The dataset was split into training and testing sets, with 80% of the data used for training and 20% for testing. Cytoscape, an open-source software platform, was employed to visualize and analyze the drug-gene interaction network, and CytoHubba, a plugin, was used to identify highly connected nodes. Topological measures were applied to determine the influence and importance of each node. GNNs were used to manage the complex relationships and dependencies within the graphs.</p><p><strong>Results: </strong>The drug-gene interaction network, comprising 815 nodes and 13,436 edges, was found to be complex and highly interconnected. It was divided into 11 components, displaying low density and heterogeneity, indicative of a sparse structure. The GNN model achieved 97% accuracy in predicting interaction types, including single protein interactions and protein complex groups.</p><p><strong>Conclusions: </strong>The study demonstrates that graph neural networks outperform traditional machine learning methods in predicting drug-gene interactions within the RTK-VEGF protein family in periodontal regeneration, highlighting their potential in advancing therapeutic strategies and drug discovery. <b>Key words:</b>Graph neural networks; drug-gene interactions; RTK-VEGF4 protein family: periodontal regeneration.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"16 12","pages":"e1454-e1458"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The expression of Methyltransferase-like 3 in dentigerous cyst and ameloblastoma.","authors":"Chatchaphan Udompatanakorn, Supisara Patcharaman, Patrayu Taebunpakul","doi":"10.4317/jced.62186","DOIUrl":"https://doi.org/10.4317/jced.62186","url":null,"abstract":"<p><strong>Background: </strong>N6-methyladenosine (m6A), the most abundant internal RNA modification in mammals, plays a critical role in many forms of cancer. Methyltransferase-like 3 (METTL3) serves as the main catalytic subunit of the m6A writer and plays a role in the progression of head and neck squamous cell carcinoma. To date, the role of METTL3 in odontogenic lesions has never been investigated. This study aimed to examine METTL3 expression in dental follicles (DF), dentigerous cysts (DC), unicystic ameloblastoma (UA), and conventional ameloblastoma (conventional AM).</p><p><strong>Material and methods: </strong>The immunohistochemistry was performed using paraffin-embedded tissue samples. Seven cases of DF, 30 cases of DC, and 35 cases of AM (20 cases of UA and 15 cases of conventional AM) were included. The expression patterns, percentage of METTL3-positive cells, staining intensities, and immunoreactive scores (IRS) were examined.</p><p><strong>Results: </strong>The percentage of METTL3-positive cells was found to be significantly higher in the AM compared to DC and DF samples (<i>p</i><0.01). Additionally, the percentage of METTL3-positive cells increased from the luminal/intraluminal subtype of UA, the mural subtype of UA, to the conventional AM (<i>p</i><0.01). All AM samples had higher METTL3 cell staining intensity and IRS scores than the DF and DC samples (<i>p</i><0.01). The mural subtype of UA and conventional AM also had significantly higher cell intensity and IRS scores than the luminal/intraluminal subtype of UA (<i>p</i><0.05).</p><p><strong>Conclusions: </strong>The results of this study suggest that METTL3 might have a role in odontogenic lesions. METTL3 expression may be related to the aggressive behaviour of these lesions. However, the precise molecular mechanism of METTL3 in odontogenic lesions still needs to be elucidated. <b>Key words:</b>Methyltransferase-like 3, immunohistochemistry, dentigerous cyst, ameloblastoma.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"16 12","pages":"e1481-e1488"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceptibility and Acceptability Thresholds for Color Differences in Ceramic Shade Tabs: A Comparison Between Dentists and Patients.","authors":"Vanessa Schussler, Daniel Yuydi Kawakami, Marco Antonio Garcia Rocha, Mario Alexandre Coelho Sinhoreti, Mateus Garcia Rocha, Dayane Oliveira","doi":"10.4317/jced.62287","DOIUrl":"https://doi.org/10.4317/jced.62287","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to evaluate the 50%:50% perceptibility thresholds (PT) and acceptability thresholds (AT) for color differences in ceramic shade tabs observed by dentists and patients using CIEDE2000 color difference formula.</p><p><strong>Material and methods: </strong>Twenty-two combinations of ceramic shade tabs from the VITA 3D Master shade guide were assembled to be used for the visual comparison analyses. The color difference between each shade tab pair was numerically determined by spectrophotometry using the VITA EasyShade V, and calculated using the CIEDE2000 formula (ΔE00). Twenty dentists and twenty patients were recruited for this study. All participants performed the visual assessment of the provided shade tab pairs under D65 illumination and a grey background, and requested to determine if they could perceive a color difference between them (PT) and whether they considered the combination clinically acceptable (AT). The correlation between numeric data of color difference between the shade tabs, and the perceptibility and acceptability thresholds given by the participants was analyzed by logistic regression (α=0.05; β=0.0085).</p><p><strong>Results: </strong>The PT for dentists was ΔE00= 2.29, and ΔE00= 2.27 for patients. The AT for dentists was ΔE00=2,41, and ΔE00=2,83 for patients. The results showed a statistically significant difference between PT and AT thresholds for both dentists and patients. However, there was no statistically significant differences in PT (<i>p</i>=0.39) or AT (<i>p</i>=0.54) between patients and dentists.</p><p><strong>Conclusions: </strong>Within the limitations of this study, it was possible to conclude that while the PT and AT vary significantly within each group, they are statistically similar between dentists and patients when discriminating color differences in ceramic tabs. <b>Key words:</b>Color difference, esthetic, aesthetic, spectrophotometry, CIEDE2000.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"16 12","pages":"e1509-e1516"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}