Journal of Clinical and Experimental Dentistry最新文献

{"title":"Influence of Wavelength on Light Transmittance, Heat Generation and Pulpal Cellular Response Across Different Restorative Procedures.","authors":"Sharanya Singh, Mateus Garcia Rocha, Alexandre Silvino, Shannon M Wallet, Mario Alexandre Coelho Sinhoreti, Dayane Oliveira","doi":"10.4317/jced.63873","DOIUrl":"https://doi.org/10.4317/jced.63873","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate the effects of different wavelengths on light transmittance, heat generation, and pulpal cellular response across different restorative procedures.</p><p><strong>Material and methods: </strong>Standardized 5mmx5mm Class I preparations and dentin discs were prepared, leaving 0.5mm of dentin at the pulpal floor using extracted third molars. Direct restorations on the Class I preparations were performed using conventional or bulk-fill composites, and 1.5mm ceramic restorations were cemented onto the dentin discs with resin cement. Light-curing procedures were performed using blue (460nm), green (520nm), and red (620nm) wavelengths at 1000 mW/cm². The degree of conversion was assessed using FTIR-ATR (Nicolet iS20). Specimens were positioned above the input sensor of a spectrophotometer (MARC-LC) for the light-transmittance analyses or in a customized oral cavity chamber simulator for temperature variations analyses using an infrared thermal camera (FLIR ONE PRO), with measurements performed on the pulpal floor. Odontoblast-like cells (MDPC-23) were exposed to the same maximum radiant exposure that reached the pulp chamber, and cell viability was assessed using an MTT assay. A power analysis was conducted to determine the sample size to provide a power of at least 0.8 with =0.05. Statistical analyses were performed using one-way ANOVA and Tukey's test.</p><p><strong>Results: </strong>Degree of conversion did not differ across wavelengths/irradiance conditions (p&gt;0.09). Across all restorative procedures tested, light transmittance to the pulpal floor increased with longer wavelengths (p&lt;0.05). Increased material thickness resulted in significant reductions in transmittance across all wavelengths (p&lt;0.001), with longer wavelengths less affected by this attenuation. Thermal analysis demonstrated that shorter wavelengths produced significantly greater temperature increases within the pulp chamber (p&lt;0.05), while red light consistently produced the lowest changes (p&lt;0.01). Cell viability analysis revealed that red light maintained cell viability at levels statistically similar to those of non-irradiated controls (p=0.23); blue and green light significantly reduced cell viability (p&lt;0.05).</p><p><strong>Conclusions: </strong>Within the limitations of this in vitro model, it was possible to conclude that longer wavelengths demonstrate increased light transmission, lower temperature rise, and higher cell viability compared to shorter wavelengths delivered at equal exposure.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"18 3","pages":"e326-e334"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13119664/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of alveolar ridge preservation using collagen and platelet-rich fibrin: A systematic review.","authors":"Julia Gil-Morales, Cosimo Galletti, Javier Flores-Fraile, Alice Rose Greethurst, Fulvia Galletti, Francisco Real-Voltas","doi":"10.4317/jced.63789","DOIUrl":"https://doi.org/10.4317/jced.63789","url":null,"abstract":"<p><strong>Background: </strong>Alveolar ridge resorption following tooth extraction may compromise future implant placement and aesthetic outcomes. Several biomaterials have been proposed to limit post-extraction dimensional changes, among which collagen-based materials and platelet-rich fibrin (PRF) are widely used. The aim of this systematic review was to evaluate the effectiveness of collagen and PRF in alveolar ridge preservation compared with spontaneous healing.</p><p><strong>Material and methods: </strong>This systematic review was conducted according to PRISMA 2020 guidelines and registered in PROSPERO (CRD42024489237). An electronic search was performed in PubMed, Scopus to identify randomized controlled trials (RCTs) published from 2014 onwards. Studies conducted in adult humans that evaluated horizontal and/or vertical alveolar ridge changes after tooth extraction were included. Risk of bias was assessed using the Cochrane RoB 2 tool.</p><p><strong>Results: </strong>Sixteen RCTs were included. Collagen-based interventions, particularly when combined with bone grafts such as deproteinized bovine bone mineral (DBBM), demonstrated a significant reduction in vertical and horizontal bone loss compared with spontaneous healing in several studies. PRF-based protocols showed heterogeneous results regarding dimensional bone preservation, with limited benefit when PRF was used alone. However, PRF-especially advanced or recurrent applications-was consistently associated with improved soft tissue healing and reduced postoperative pain. Considerable heterogeneity was observed in biomaterial preparation, application protocols, follow-up duration, and outcome assessment.</p><p><strong>Conclusions: </strong>Both collagen and PRF can contribute to alveolar ridge preservation after tooth extraction, although their clinical benefits differ. Collagen, particularly when combined with bone grafts, appears more effective in preserving alveolar dimensions, while PRF provides greater advantages in soft tissue healing and postoperative pain control. The choice of biomaterial should be guided by the clinical objective and extraction site. Further well-designed, standardized long-term RCTs are needed to establish definitive clinical recommendations.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"18 3","pages":"e402-e412"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13119561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How uncommon is the occurrence of orthokeratinized odontogenic cyst in the maxilla? A systematic review and a new case report.","authors":"Dhara Schrok Monteiro de Ataide, Kaique Alberto Preto, Gabriela Lopes Dos Santos, Beethoven Estevão Costa, Roberto Yoshio Kawakami, Denise Tostes Oliveira","doi":"10.4317/jced.63735","DOIUrl":"https://doi.org/10.4317/jced.63735","url":null,"abstract":"<p><strong>Background: </strong>The orthokeratinized odontogenic cyst (OOC) is a benign intraosseous lesion, typically found in the posterior mandible in male patients in the third and fourth decades of life. Although there has been a growing number of documented cases in the last decade, the prevalence and unique characteristics of maxillary OOC remain poorly understood.</p><p><strong>Material and methods: </strong>To assess how uncommon is OOC occurrence in the maxilla, a systematic review of the literature was conducted using the major electronic databases and rigorous criteria, including a new case report involving a young male patient.</p><p><strong>Results: </strong>A total of 36 OOC located specifically in the maxilla was analyzed. The results demonstrated that OOC in the maxilla is a rare finding. Interestingly, the majority of instances are associated with an impacted tooth, mainly unerupted third molars and canines, a pattern previously unexplored in the literature. An isolated occurrence of an OOC in the posterior maxilla without involvement of a third molar tooth, as observed in this present case, is relatively uncommon and has been reported in only five other cases. Careful enucleation and curettage with removal of the impacted teeth, when present, followed by histopathological analysis, has proven to be the most effective approach for accurate diagnosis and clinical success.</p><p><strong>Conclusions: </strong>This study reinforces that orthokeratinized odontogenic cysts should be included in the differential diagnosis of intraosseous lesions in the maxilla, especially when associated with unerupted third molars and canines, which may clinically resemble dentigerous cysts.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"18 3","pages":"e394-e401"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13119594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Oral Epithelial Dysplasia with Sociodemographic and Clinical Characteristics in Individuals with Oral Lichen Planus and Oral Lichenoid Lesion.","authors":"Letícia Côgo Marques, Simone Sant'Anna Gonçalves Barbosa, Danielle Nobre Lopes, Karin Soares Cunha, Arley Silva Junior, Danielle Castex Conde","doi":"10.4317/jced.63588","DOIUrl":"https://doi.org/10.4317/jced.63588","url":null,"abstract":"<p><strong>Background: </strong>Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are potentially malignant disorders that share clinical and histopathological features. Oral epithelial dysplasia (OED) is a key indicator of malignant transformation risk in these disorders. This study aimed to investigate possible associations between the severity of OED and sociodemographic variables, hepatitis C infection, and clinical aspects in patients with OLP and OLL.</p><p><strong>Material and methods: </strong>The sample comprised 65 biopsies from 56 participants with OLP or OLL, classified according to the criteria of the American Academy of Oral and Maxillofacial Pathology (excluding the absence of OED as a diagnostic criterion for OLP). Data were retrieved from electronic medical records, and photographs taken at the time of biopsy were independently reviewed by two stomatologists and one oral pathologist to classify the clinical patterns. The presence and severity of OED were assessed according to the 2017 World Health Organization system and evaluated independently by two oral pathologists.</p><p><strong>Results: </strong>A statistically significant association was observed between OED severity and patient age (p=0.004). No significant associations were found with sex, skin color, harmful habits, hepatitis C history, clinical pattern, or anatomical site.</p><p><strong>Conclusions: </strong>Older patients were more likely to present moderate/severe OED, highlighting the importance of age as a risk factor for progression in OLP and OLL.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"18 3","pages":"e386-e393"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13119519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sample size calculation practices in original research articles of the Journal of Conservative Dentistry and Endodontics (2021-2025).","authors":"Marco Sánchez-Tito","doi":"10.4317/jced.63814","DOIUrl":"https://doi.org/10.4317/jced.63814","url":null,"abstract":"<p><strong>Background: </strong>Sample size calculation is essential for methodological rigor and statistical validity in dental research, yet deficiencies in its reporting and coherence with statistical analysis remain frequent. This study aimed to evaluate the frequency and methodological coherence of sample size calculation practices in original research articles published in the Journal of Conservative Dentistry and Endodontics (JCDE).</p><p><strong>Material and methods: </strong>A methodological review was conducted, including original research articles published between January 2021 and December 2025. Extracted variables comprised study design, sample size reporting, characteristics of the sample size calculation, statistical tests applied, and coherence between the calculation model and the final analysis. Study designs were grouped into in vitro, clinical, and observational categories. Descriptive statistics were summarized using absolute and relative frequencies. Bivariate associations were assessed using the chi-square test, and multivariable logistic regression was used to identify factors independently associated with methodological coherence.</p><p><strong>Results: </strong>Of 631 eligible articles, 176 (27.9%) reported a sample size calculation. Complete and methodologically coherent reporting was identified in only 9 studies (1.43%). Methodological coherence differed significantly by study design in bivariate analyses (p &lt; 0.05). In the adjusted model, clinical and observational studies showed higher odds of coherent sample size calculation compared with in vitro studies.</p><p><strong>Conclusions: </strong>Sample size calculations in JCDE are infrequently reported and often methodologically incoherent. Study design appears to be a key determinant of coherence, underscoring the need for improved integration of statistical planning and reporting standards.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"18 3","pages":"e366-e376"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13119605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Appearance of necrotizing sialometaplasia temporarily associated with MDMA consumption.","authors":"Eymi Plaza-Matos, José López-Vicente, Nerea Larrea-Rodríguez, Javier Alberdi-Navarro","doi":"10.4317/jced.63836","DOIUrl":"https://doi.org/10.4317/jced.63836","url":null,"abstract":"<p><p>We reported the case of a 24-year-old woman presented with necrotizing sialometaplasia associated temporally with 3,4-methylenedioxymethamphetamine (MDMA) use. The patient reported having consumed MDMA powder licked onto the oral mucosa days before the appearance of the lesions. Symptomatic treatment of the presenting lesions was carried out, with a follow-up that demonstrated complete healing of the lesions. The clinical case is presented and possible pathophysiological mechanisms that may justify the relationship between MDMA and necrotizing sialometaplasia are discussed. This report describes the relationship between a new, previously undescribed aetiological factor related to necrotizing sialometaplasia.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"18 3","pages":"e420-e423"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13119550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-ulcerated Necrotizing Sialometaplasia: A case series.","authors":"Constanza Godoy-Latorre, Macarena Rodríguez-Luengo, Rolando Morales, Pablo Córdova, Maureen Marshall, René Martínez, Sven Eric Niklander","doi":"10.4317/jced.63606","DOIUrl":"https://doi.org/10.4317/jced.63606","url":null,"abstract":"<p><p>Necrotizing sialometaplasia is an uncommon, locally destructive inflammatory condition that most frequently affects the minor salivary glands of the palate, although salivary glands at other sites can also be affected. Its clinical presentation is generally characterized by the presence of a painful, ulcerated swelling, but in the early stages, it might not be ulcerated which makes its diagnosis very challenging. Although it is a benign, self-limited condition, care must be taken during diagnosis, as it can mimic malignant processes, both clinically and histologically. Here we report three uncommon cases of non-ulcerated necrotizing sialometaplasia with its clinical and histopathological characteristics.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"18 3","pages":"e424-e427"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13119520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nerve Combing for Idiopathic Trigeminal Neuralgia Without Neurovascular Compression.","authors":"Yoshihito Maruyama, Keita Takizawa, Kana Kawai-Ozasa, Andrew Young, Naoki Otani, Noboru Noma","doi":"10.4317/jced.63726","DOIUrl":"https://doi.org/10.4317/jced.63726","url":null,"abstract":"<p><p>Trigeminal neuralgia (TN) is classified into classical, secondary, and idiopathic forms, but the pathophysiology and optimal surgical management of idiopathic TN remain controversial, especially in the absence of definite neurovascular compression. We report two cases of idiopathic TN successfully treated with nerve combing combined with posterior fossa exploration. A 44-year-old woman and a 73-year-old man presented with medically refractory paroxysmal facial pain, and preoperative MRI demonstrated vascular contact without clear compression. Intraoperatively, thickened arachnoid adhesions and axial torsion of the trigeminal nerve root were identified. Meticulous arachnoid dissection restored normal nerve alignment, followed by nerve combing. In one case, intraoperative compound nerve action potential monitoring suggested reduced neural hyperexcitability. Both patients achieved complete postoperative pain relief with only transient sensory disturbances. These cases indicate that axial torsion of the trigeminal nerve root caused by arachnoid adhesions may play a role in the pathophysiology of idiopathic TN. A diagnostic trial of carbamazepine can serve as a valuable adjunct for the clinical diagnosis of orofacial pain disorders suggestive of trigeminal neuralgia, even in the absence of neurovascular compression on MRI. Furthermore, nerve combing combined with meticulous arachnoid dissection may represent an effective surgical strategy for select patients.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"18 3","pages":"e428-e432"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13119554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of gingival condition in asthmatic children.","authors":"Andrea Ruiz-Hernández, Francisco Javier Silvestre, Miguel Tortajada-Girbés, Javier Silvestre-Rangil","doi":"10.4317/jced.63556","DOIUrl":"https://doi.org/10.4317/jced.63556","url":null,"abstract":"<p><strong>Background: </strong>Asthma is considered to be the most common chronic respiratory disorder in children, and it has been suggested that asthmatic children may be at an increased risk of developing gingival disease. A study was made to evaluate the level of oral hygiene and gingival health in asthmatic children, and to explore their possible relationship with the severity of asthma.</p><p><strong>Materials and methods: </strong>A total of 187 children (108 with asthma and 79 healthy controls) between 6-16 years of age were studied. A questionnaire was used to collect information on habits of oral hygiene. The presence of mouth breathing was recorded, and an oral clinical examination was carried out based on the following indices: Silness-Löe plaque index, simplified Greene-Vermillion oral hygiene index, Löe-Silness gingival index, Ainamo and Bay bleeding on probing index, and the community periodontal index (CPI). The severity of asthma was classified following the recommendations of the Spanish Guide on the Management of Asthma (Guía Española para el Manejo del Asma [GEMA]).</p><p><strong>Results: </strong>The level of oral hygiene was similar in both groups. Mouth breathing was more frequent among the asthmatic children (p&lt;0.001), and the gingival index and bleeding on probing scores were higher (p=0.005 and p=0.013, respectively).</p><p><strong>Conclusions: </strong>Mouth breathing was more common in the asthmatic children, and they had higher gingival index and bleeding on probing scores than the healthy controls, despite good habits of oral hygiene.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"18 3","pages":"e335-e341"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13119515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonsurgical Periodontal Therapy for Diabetes Patients with Periodontal Disease.","authors":"María José Moya-Villaescusa, Arturo Sánchez-Pérez, Marta Arráez-Monllor, Paloma Portillo-Ortega, Bibiana Mateos-Moreno","doi":"10.4317/jced.63729","DOIUrl":"https://doi.org/10.4317/jced.63729","url":null,"abstract":"<p><strong>Background: </strong>Diabetes mellitus (DM) and periodontitis are chronic conditions with a well-established bidirectional relationship. This interaction not only worsens periodontitis severity but also complicates glycemic control. We aimed to determine whether nonsurgical periodontal treatment reduces glycosylated hemoglobin (HbA1c) levels at 3 and 6 months in type II diabetic patients with periodontal disease.</p><p><strong>Material and methods: </strong>In this sequential case-control study conducted at the University Dental Clinic in Murcia, Spain, we enrolled thirty diabetic patients. Participants were allocated to either a test group (receiving comprehensive periodontal treatment with scaling and root planing) or a control group (receiving supragingival plaque removal only). Both groups received oral hygiene instructions. We evaluated periodontal parameters (HI, GBI, PPD, CAL) and HbA1c levels at baseline, 3, and 6 months, analyzing data with repeated-measures ANOVA and Bonferroni correction.</p><p><strong>Results: </strong>The periodontal treatment group demonstrated statistically significant reductions in HbA1c levels at both 3 and 6 months post-treatment (p &lt; 0.05). In contrast, we observed no significant changes in the control group.</p><p><strong>Conclusions: </strong>Our findings indicate that periodontal disease associates with elevated HbA1c levels in diabetic patients. Nonsurgical periodontal treatment significantly reduces both periodontal inflammation and HbA1c levels at 3 and 6 months, supporting its integration into comprehensive diabetes management.</p>","PeriodicalId":15376,"journal":{"name":"Journal of Clinical and Experimental Dentistry","volume":"18 3","pages":"e303-e308"},"PeriodicalIF":0.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13119648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147772841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}