Journal of Cancer Epidemiology最新文献_第8页

Determinants of Cervical Cancer Screening Uptake among Women in Ilorin, North Central Nigeria: A Community-Based Study 尼日利亚中北部伊洛林妇女宫颈癌筛查的决定因素:一项基于社区的研究

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2016-01-06 DOI: 10.1155/2016/6469240

A. Idowu, S. olowookere, A. Fagbemi, O. Ogunlaja

{"title":"Determinants of Cervical Cancer Screening Uptake among Women in Ilorin, North Central Nigeria: A Community-Based Study","authors":"A. Idowu, S. olowookere, A. Fagbemi, O. Ogunlaja","doi":"10.1155/2016/6469240","DOIUrl":"https://doi.org/10.1155/2016/6469240","url":null,"abstract":"Introduction. Cancer of the cervix is the leading cause of cancer deaths among women in developing countries. Screening is one of the most cost effective control strategies for the disease. This study assessed the determinants of cervical cancer screening uptake among Nigerian women. Methodology. This cross-sectional study was conducted using multistage sampling technique among 338 participants in Ilorin, North Central Nigeria. A pretested questionnaire was used for data collection and data analysis was done using SPSS version 21. Chi-square test was used for bivariate analysis while binary logistic regression was used for multivariate analysis. Statistical significance was set at p < 0.05. Results. Only 8.0% of the respondents had ever been screened for cancer of the cervix. The proportion of women who had ever been screened was significantly higher among those who demonstrated positive attitude to screening (81.5%, p = 0.001), respondents who were aware of the disease (100.0%, p = 0.001), and those who were aware of cervical cancer screening (88.9%, p = 0.001). Respondents who had negative attitude had 63% lesser odds of being screened compared to those who had positive attitudes towards screening (AOR; 0.37, 95% CI; 0.01–0.28). Conclusion. There is urgent need to improve the knowledge base and attitude of Nigerian women to enhance cervical cancer screening uptake among them.","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":"2016 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2016-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/6469240","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64479725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 87

Prostate Cancer Screening in Jamaica: Results of the Largest National Screening Clinic. 牙买加的前列腺癌筛查：最大的全国筛查诊所的结果。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2016-01-01 Epub Date: 2016-02-29 DOI: 10.1155/2016/2606805

Belinda F Morrison, William Aiken, Richard Mayhew, Yulit Gordon, Marvin Reid

{"title":"Prostate Cancer Screening in Jamaica: Results of the Largest National Screening Clinic.","authors":"Belinda F Morrison, William Aiken, Richard Mayhew, Yulit Gordon, Marvin Reid","doi":"10.1155/2016/2606805","DOIUrl":"10.1155/2016/2606805","url":null,"abstract":"Prostate cancer is highly prevalent in Jamaica and is the leading cause of cancer-related deaths. Our aim was to evaluate the patterns of screening in the largest organized screening clinic in Jamaica at the Jamaica Cancer Society. A retrospective analysis of all men presenting for screening at the Jamaica Cancer Society from 1995 to 2005 was done. All patients had digital rectal examinations (DRE) and prostate specific antigen (PSA) tests done. Results of prostate biopsies were noted. 1117 men of mean age 59.9 ± 8.2 years presented for screening. The median documented PSA was 1.6 ng/mL (maximum of 5170 ng/mL). Most patients presented for only 1 screen. There was a gradual reduction in the mean age of presentation for screening over the period. Prostate biopsies were requested on 11% of screening visits; however, only 59% of these were done. 5.6% of all persons screened were found to have cancer. Of the cancers diagnosed, Gleason 6 adenocarcinoma was the commonest grade and median PSA was 8.9 ng/mL (range 1.5-1059 ng/mL). Older men tend to screen for prostate cancer in Jamaica. However, compliance with regular maintenance visits and requests for confirmatory biopsies are poor. Screening needs intervention in the Jamaican population. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":"2016 1","pages":"2606805"},"PeriodicalIF":1.8,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64285806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What Prevents Men Aged 40-64 Years from Prostate Cancer Screening in Namibia? 在纳米比亚，是什么阻止40-64岁的男性进行前列腺癌筛查?

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2016-01-01 Epub Date: 2016-01-10 DOI: 10.1155/2016/7962502

Joseph Kangmennaang, Paul Mkandawire, Isaac Luginaah

{"title":"What Prevents Men Aged 40-64 Years from Prostate Cancer Screening in Namibia?","authors":"Joseph Kangmennaang, Paul Mkandawire, Isaac Luginaah","doi":"10.1155/2016/7962502","DOIUrl":"10.1155/2016/7962502","url":null,"abstract":"Objectives. Although a growing body of evidence demonstrates the public health burden of prostate cancer in SSA, relatively little is known about the underlying factors surrounding the low levels of testing for the disease in the context of this region. Using Namibia Demographic Health Survey dataset (NDHS, 2013), we examined the factors that influence men's decision to screen for prostate cancer in Namibia. Methods. We use complementary log-log regression models to explore the determinants of screening for prostate cancer. We also corrected for the effect of unobserved heterogeneity that may affect screening behaviours at the cluster level. Results. The results show that health insurance coverage (OR = 2.95, p = 0.01) is an important predictor of screening for prostate cancer in Namibia. In addition, higher education and discussing reproductive issues with a health worker (OR = 2.02, p = 0.05) were more likely to screening for prostate cancer. Conclusions. A universal health insurance scheme may be necessary to increase uptake of prostate cancer screening. However it needs to be acknowledged that expanded screening can have negative consequences and any allocation of scarce resources towards screening must be guided by evidence obtained from the local context about the costs and benefits of screening. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":"2016 1","pages":"7962502"},"PeriodicalIF":1.8,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/7962502","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64542473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 25

Coffee Consumption and the Incidence of Colorectal Cancer in Women. 饮用咖啡与女性结直肠癌的发病率

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2016-01-01 Epub Date: 2016-04-28 DOI: 10.1155/2016/6918431

Erik J Groessl, Matthew A Allison, Joseph C Larson, Samuel B Ho, Linda G Snetslaar, Dorothy S Lane, Katie M Tharp, Marcia L Stefanick

{"title":"Coffee Consumption and the Incidence of Colorectal Cancer in Women.","authors":"Erik J Groessl, Matthew A Allison, Joseph C Larson, Samuel B Ho, Linda G Snetslaar, Dorothy S Lane, Katie M Tharp, Marcia L Stefanick","doi":"10.1155/2016/6918431","DOIUrl":"https://doi.org/10.1155/2016/6918431","url":null,"abstract":"Background. Higher coffee consumption has been associated with decreased incidence of colorectal cancer. Our objective was to examine the relationship of coffee intake to colorectal cancer incidence in a large observational cohort of postmenopausal US women. Methods. Data were collected for the Women's Health Initiative Observational Study providing a follow-up period of 12.9 years. The mean age of our sample (N = 83,778 women) was 63.5 years. Daily coffee intake was grouped into 3 categories: None, moderate (>0-<4 cups), and high (4+ cups). Proportional hazards modeling was used to evaluate the relationship between coffee intake and colorectal cancer. Results. There were 1,282 (1.53%) new cases of colorectal cancer during follow-up. Compared to nondrinkers, moderate and high coffee drinkers had an increased incidence of colorectal cancer in multivariate analysis (HR 1.15, 1.02-1.29; HR 1.14, 0.93-1.38). Moderate drip brew coffee intake (HR 1.20, 1.05-1.36) and high nondrip brew coffee intake (HR 1.43, 1.01-2.02) were associated with increased odds. Conclusion. Our results suggesting increased incidence of colorectal cancer associated with higher coffee consumption contradict recent meta-analyses but agree with a number of other studies showing that coffee increases risk or has no effect. Brew method results are novel and warrant further research. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":"2016 ","pages":"6918431"},"PeriodicalIF":1.8,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/6918431","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34528508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Promoter Methylation and mRNA Expression of Response Gene to Complement 32 in Breast Carcinoma. 乳腺癌启动子甲基化及补体32应答基因mRNA表达。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2016-01-01 Epub Date: 2016-03-29 DOI: 10.1155/2016/7680523

Ebrahim Eskandari-Nasab, Mohammad Hashemi, Firoozeh Rafighdoost

{"title":"Promoter Methylation and mRNA Expression of Response Gene to Complement 32 in Breast Carcinoma.","authors":"Ebrahim Eskandari-Nasab, Mohammad Hashemi, Firoozeh Rafighdoost","doi":"10.1155/2016/7680523","DOIUrl":"https://doi.org/10.1155/2016/7680523","url":null,"abstract":"Background. Response gene to complement 32 (RGC32), induced by activation of complements, has been characterized as a cell cycle regulator; however, its role in carcinogenesis is still controversial. In the present study we compared RGC32 promoter methylation patterns and mRNA expression in breast cancerous tissues and adjacent normal tissues. Materials and Methods. Sixty-three breast cancer tissues and 63 adjacent nonneoplastic tissues were included in our study. Design. Nested methylation-specific polymerase chain reaction (Nested-MSP) and quantitative PCR (qPCR) were used to determine RGC32 promoter methylation status and its mRNA expression levels, respectively. Results. RGC32 methylation pattern was not different between breast cancerous tissue and adjacent nonneoplastic tissue (OR = 2.30, 95% CI = 0.95-5.54). However, qPCR analysis displayed higher levels of RGC32 mRNA in breast cancerous tissues than in noncancerous tissues (1.073 versus 0.959; P = 0.001), irrespective of the promoter methylation status. The expression levels and promoter methylation of RGC32 were not correlated with any of patients' clinical characteristics (P > 0.05). Conclusion. Our findings confirmed upregulation of RGC32 in breast cancerous tumors, but it was not associated with promoter methylation patterns. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":"2016 ","pages":"7680523"},"PeriodicalIF":1.8,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/7680523","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34494960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

The Prevalence of HIV in Cancer Patients at the Surgical Oncology Unit of Donka University Hospital of Conakry (Guinea) 科纳克里东卡大学医院外科肿瘤科癌症患者的艾滋病毒感染率(几内亚)

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2015-12-03 DOI: 10.1155/2015/387896

B. Traore, Thierno‐Souleymane Bah, F. Traoré, M. S. Sow, Solomana Diane, M. Keita, M. Cissé, M. Koulibaly, Naby Daouda Camara

{"title":"The Prevalence of HIV in Cancer Patients at the Surgical Oncology Unit of Donka University Hospital of Conakry (Guinea)","authors":"B. Traore, Thierno‐Souleymane Bah, F. Traoré, M. S. Sow, Solomana Diane, M. Keita, M. Cissé, M. Koulibaly, Naby Daouda Camara","doi":"10.1155/2015/387896","DOIUrl":"https://doi.org/10.1155/2015/387896","url":null,"abstract":"Aim. To determine the prevalence of HIV infection among patients seen at the surgical oncology unit of Donka (Conakry, Guinea). Method. We conducted a retrospective and descriptive study of HIV infection in cancer patients from May 2007 to December 2012. Social characteristics (age, gender, marital status, and education) and immune status (HIV type, CD4 count) were reviewed. Results. Out of 2598 cancer patients, 54 (2.1%) tested positive for HIV. There were 11 (20.4%) defining AIDS and 43 (79.6%) nondefining AIDS cancers. The most frequent cancers were breast (14) (26.0%), non-Hodgkin lymphoma (6) (11.1%), liver (6) (11.1%), eye and annexes (6) (11.1%), and cervical cancer (5) (9.3%). These patients were female in 34 (63.0%) and had a median age of 39 years and body mass index was 20,3 Kg/m2. They were unschooled in 40 (74.1%) and married in 35 (64.8%). CD4 count showed a median of 317 cells/mL. Antiretroviral treatment was performed in 40 (74.1%). Conclusion. HIV prevalence is higher in patients in our unit of surgical oncology. Breast cancer was the most common in this association. A national survey of a large sample is needed to determine the true prevalence and impact of HIV on cancer prognosis.","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":"2015 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2015-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/387896","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64938716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Incidence of Gastric Cancer in Marrakech and Casablanca, Morocco 摩洛哥马拉喀什和卡萨布兰卡地区胃癌发病率分析

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2015-10-21 DOI: 10.1155/2015/704569

Brittney L. Smith, M. Khouchani, M. Karkouri, A. Lazenby, K. Watkins, A. Tahri, A. Benider, S. Rajaram, A. Soliman

{"title":"Incidence of Gastric Cancer in Marrakech and Casablanca, Morocco","authors":"Brittney L. Smith, M. Khouchani, M. Karkouri, A. Lazenby, K. Watkins, A. Tahri, A. Benider, S. Rajaram, A. Soliman","doi":"10.1155/2015/704569","DOIUrl":"https://doi.org/10.1155/2015/704569","url":null,"abstract":"Gastric cancer is the fifth most common cancer globally with over 70% of new cases occurring in developing countries. In Morocco, oncologists in Marrakech suspected higher frequency of gastric cancer compared to Casablanca, a city 150 kilometers away. This study calculated age-specific, sex-specific, and total incidence rates of gastric cancer in Marrakech and was compared to the Casablanca population-based cancer registry. Using medical records from Center Hospital University Mohammad VI and reports from 4 main private pathology laboratories in Marrakech, we identified 774 patients for the period 2008–2012. Comparison of rates showed higher age-specific incidence in Marrakech in nearly all age groups for both genders. A higher total incidence in Marrakech than in Casablanca was found with rates of 5.50 and 3.23 per 100,000, respectively. Incidence was significantly higher among males in Marrakech than males in Casablanca (7.19 and 3.91 per 100,000, resp.) and females in Marrakech compared to females in Casablanca (3.87 and 2.58 per 100,000, resp.). Future studies should address possible underestimation of gastric cancer in Marrakech, estimate incidence in other regions of Morocco, and investigate possible risk factors to explain the difference in rates.","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":"2015 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2015-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/704569","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65109097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Patterns of Benign and Malignant Lesions of the Thyroid in Two Wilayahs of Northeastern Algeria. 阿尔及利亚东北部两个Wilayahs的甲状腺良性和恶性病变模式。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2015-01-01 Epub Date: 2015-11-22 DOI: 10.1155/2015/849416

Mona Guidoum, Hind Kherfi-Kadi, Ouahiba Benharkat-Boughaba, Aicha Djemaa-Bendjazia, Sihem Keghouche, Behnoush Abedi-Ardekani, Amina Azzouz, Yacine Kadi, Pierre Hainaut, Zihad Bouslama

{"title":"Patterns of Benign and Malignant Lesions of the Thyroid in Two Wilayahs of Northeastern Algeria.","authors":"Mona Guidoum, Hind Kherfi-Kadi, Ouahiba Benharkat-Boughaba, Aicha Djemaa-Bendjazia, Sihem Keghouche, Behnoush Abedi-Ardekani, Amina Azzouz, Yacine Kadi, Pierre Hainaut, Zihad Bouslama","doi":"10.1155/2015/849416","DOIUrl":"10.1155/2015/849416","url":null,"abstract":"The aim of this study is to compare histological patterns and to estimate the burden of thyroid cancers in the two Wilayahs (departments) of El-Taref and Guelma in northeast of Algeria (total population 0.9 million), locally reputed as having different rates of endemic thyroid diseases and cancer. A retrospective analysis of central pathology registers and clinical records of patients with thyroid diseases, covering the period 2008-2012, was conducted. A total of 145 cases of thyroid cancers with histological confirmation were registered in the two Wilayahs during the period, with a female to male ratio of 5.9 : 1. Estimates of crude incidence rates suggested that thyroid cancers were twice as frequent in the Wilayah of Guelma compared to El-Taref (p < 0.05) with a tendency to occur at a younger age in resident of the Wilayah of El-Taref. Diagnoses of thyroid adenoma were more frequent in the Wilayah of Guelma, whereas the prevalence of other thyroid lesions, including goitre, was similar in the two Wilayahs. This first descriptive study on geographic variations in thyroid cancer in Northern Africa suggests that significant differences may occur in relation with environmental and lifestyle exposures. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":"2015 1","pages":"849416"},"PeriodicalIF":1.8,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65182916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Diabetes Status and Medication on Presentation, Treatment, and Outcome of Stage II Colon Cancer Patients. 糖尿病状态和药物对II期结肠癌患者的表现、治疗和结局的影响

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2015-01-01 Epub Date: 2015-05-05 DOI: 10.1155/2015/189132

Susie Bae, Hui-Li Wong, Jeanne Tie, Jayesh Desai, Kathryn Field, Suzanne Kosmider, Spiros Fourlanos, Ian Jones, Iain Skinner, Peter Gibbs

{"title":"Impact of Diabetes Status and Medication on Presentation, Treatment, and Outcome of Stage II Colon Cancer Patients.","authors":"Susie Bae, Hui-Li Wong, Jeanne Tie, Jayesh Desai, Kathryn Field, Suzanne Kosmider, Spiros Fourlanos, Ian Jones, Iain Skinner, Peter Gibbs","doi":"10.1155/2015/189132","DOIUrl":"https://doi.org/10.1155/2015/189132","url":null,"abstract":"Diabetes is a risk factor for colorectal cancer and several reports suggest worse cancer-specific outcomes in diabetes patients. Recent studies in multiple tumour types indicate metformin may positively impact on cancer-specific and overall survival. A population-based series of stage II colorectal cancer patients treated and followed from 2000 to 2013 were analysed for baseline characteristics, treatment, and outcomes. 1116 patients with stage II colon cancer were identified, 55.5% were male and median age was 70.9 years (range 20.5-101.2). The diabetes patients (21.6%, n = 241) were older than nondiabetes patients (median 74.0 versus 69.6, p = 0.0001). There was no impact of diabetes on cancer presentation or pathology. Diabetes patients were less likely to receive adjuvant treatment (13.7 versus 24.8%, p = 0.002) but were equally likely to complete treatment (69.7 versus 67.7%, p = 1.00). Diabetes did not significantly impact cancer recurrence (HR = 1.07, 95% CI 0.71-1.63) or overall survival (HR = 1.23, 95% CI 0.88-1.72), adjusted for age. Diabetes medication did not impact cancer recurrence or survival. Cancer presentation and outcomes in diabetes patients are comparable to those of nondiabetes patients in those with stage II colon cancer. The effect of metformin merits further evaluation in patients with colon cancer. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":"2015 ","pages":"189132"},"PeriodicalIF":1.8,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/189132","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33263378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Non-Small-Cell Lung Cancer Clinicopathologic Features and Survival Outcomes in Asian Pacific Islanders Residing in the United States: A SEER Analysis. 居住在美国的亚太岛民的非小细胞肺癌临床病理特征和生存结果:一项SEER分析

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2015-01-01 Epub Date: 2015-01-15 DOI: 10.1155/2015/269304

Muhammad Saad Hamid, Raji Shameem, Khalid Gafoor, Jason George, Bushra Mina, Kevin Sullivan

{"title":"Non-Small-Cell Lung Cancer Clinicopathologic Features and Survival Outcomes in Asian Pacific Islanders Residing in the United States: A SEER Analysis.","authors":"Muhammad Saad Hamid, Raji Shameem, Khalid Gafoor, Jason George, Bushra Mina, Kevin Sullivan","doi":"10.1155/2015/269304","DOIUrl":"https://doi.org/10.1155/2015/269304","url":null,"abstract":"Background. The objective of our study was to ascertain racial/ethnic disparities in Asian/Pacific Islanders (API) for non-small-cell lung cancer (NSCLC) clinicopathologic features and survival outcomes based on various tumor characteristics and treatment modalities. Method. SEER database identified invasive NSCLC cases from 2004 to 2010. Variables included American Joint Committee on Cancer (AJCC) stage 7, tumor grade, tumor size, histology, age, marital status, radiation, surgery, and reason for no surgery. The Kruskall-Wallis test and the Z test were used to examine differences between races/ethnicities and the referent, non-Hispanic white (NHW). Multivariate Cox proportional analyses were used to establish the weight of the prognostic significance contributing to disease-specific survival (DSS) in each AJCC stage. Result. Improved DSS was seen in API across stage I (HR: 0.78), stage II (HR: 0.79), and stage IV (HR: 0.86), respectively, compared to the referent NHW (P < 0.01). Prognosis was improved by being married, being female gender, AIS histology, and birth outside the US (P < 0.01). Conclusion. We have demonstrated improved survival among API in early stage and stage IV NSCLC. Further research is necessary to clarify the role of lifestyle and tumor biology for these differences.","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":"2015 ","pages":"269304"},"PeriodicalIF":1.8,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2015/269304","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33057632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8