Journal of Cancer Epidemiology最新文献_第10页

Cancer incidence in egypt: results of the national population-based cancer registry program. 埃及癌症发病率:国家基于人口的癌症登记项目的结果。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2014-01-01 Epub Date: 2014-09-21 DOI: 10.1155/2014/437971

Amal S Ibrahim, Hussein M Khaled, Nabiel Nh Mikhail, Hoda Baraka, Hossam Kamel

{"title":"Cancer incidence in egypt: results of the national population-based cancer registry program.","authors":"Amal S Ibrahim, Hussein M Khaled, Nabiel Nh Mikhail, Hoda Baraka, Hossam Kamel","doi":"10.1155/2014/437971","DOIUrl":"https://doi.org/10.1155/2014/437971","url":null,"abstract":"Background. This paper aims to present cancer incidence rates at national and regional level of Egypt, based upon results of National Cancer Registry Program (NCRP). Methods. NCRP stratified Egypt into 3 geographical strata: lower, middle, and upper. One governorate represented each region. Abstractors collected data from medical records of cancer centers, national tertiary care institutions, Health Insurance Organization, Government-Subsidized Treatment Program, and death records. Data entry was online. Incidence rates were calculated at a regional and a national level. Future projection up to 2050 was also calculated. Results. Age-standardized incidence rates per 100,000 were 166.6 (both sexes), 175.9 (males), and 157.0 (females). Commonest sites were liver (23.8%), breast (15.4%), and bladder (6.9%) (both sexes): liver (33.6%) and bladder (10.7%) among men, and breast (32.0%) and liver (13.5%) among women. By 2050, a 3-fold increase in incident cancer relative to 2013 was estimated. Conclusion. These data are the only available cancer rates at national and regional levels of Egypt. The pattern of cancer indicated the increased burden of liver cancer. Breast cancer occupied the second rank. Study of rates of individual sites of cancer might help in giving clues for preventive programs. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/437971","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32757633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 866

Breast Cancer Survival Defined by the ER/PR/HER2 Subtypes and a Surrogate Classification according to Tumor Grade and Immunohistochemical Biomarkers. 乳腺癌生存由ER/PR/HER2亚型和肿瘤分级和免疫组织化学生物标志物的替代分类定义。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2014-01-01 Epub Date: 2014-05-26 DOI: 10.1155/2014/469251

Carol A Parise, Vincent Caggiano

{"title":"Breast Cancer Survival Defined by the ER/PR/HER2 Subtypes and a Surrogate Classification according to Tumor Grade and Immunohistochemical Biomarkers.","authors":"Carol A Parise, Vincent Caggiano","doi":"10.1155/2014/469251","DOIUrl":"https://doi.org/10.1155/2014/469251","url":null,"abstract":"Introduction. ER, PR, and HER2 are routinely available in breast cancer specimens. The purpose of this study is to contrast breast cancer-specific survival for the eight ER/PR/HER2 subtypes with survival of an immunohistochemical surrogate for the molecular subtype based on the ER/PR/HER2 subtypes and tumor grade. Methods. We identified 123,780 cases of stages 1-3 primary female invasive breast cancer from California Cancer Registry. The surrogate classification was derived using ER/PR/HER2 and tumor grade. Kaplan-Meier survival analysis and Cox proportional hazards modeling were used to assess differences in survival and risk of mortality for the ER/PR/HER2 subtypes and surrogate classification within each stage. Results. The luminal B/HER2- surrogate classification had a higher risk of mortality than the luminal B/HER2+ for all stages of disease. There was no difference in risk of mortality between the ER+/PR+/HER2- and ER+/PR+/HER2+ in stage 3. With one exception in stage 3, the ER-negative subtypes all had an increased risk of mortality when compared with the ER-positive subtypes. Conclusions. Assessment of survival using ER/PR/HER2 illustrates the heterogeneity of HER2+ subtypes. The surrogate classification provides clear separation in survival and adjusted mortality but underestimates the wide variability within the subtypes that make up the classification. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/469251","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32446644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 232

Smokeless tobacco and oral cancer in South Asia: a systematic review with meta-analysis. 南亚的无烟烟草与口腔癌：系统回顾与荟萃分析。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2014-01-01 Epub Date: 2014-07-06 DOI: 10.1155/2014/394696

Zohaib Khan, Justus Tönnies, Steffen Müller

{"title":"Smokeless tobacco and oral cancer in South Asia: a systematic review with meta-analysis.","authors":"Zohaib Khan, Justus Tönnies, Steffen Müller","doi":"10.1155/2014/394696","DOIUrl":"10.1155/2014/394696","url":null,"abstract":"Introduction. Smokeless tobacco is considered one of the major risk factors for oral cancer. It is estimated that over 90% of the global smokeless tobacco use burden is in South Asia. This paper aims to systematically review publications reporting epidemiological observational studies published in South Asia from 1984 till 2013. Methods. An electronic search in \"Medline\" and \"ISI Web of Knowledge\" yielded 734 publications out of which 21 were included in this review. All publications were assessed for quality using a standard quality assessment tool. Effect estimates (odds ratios (OR)) were abstracted or calculated from the given data. A random effects meta-analysis was performed to assess the risk of oral cancer with the use of different forms of smokeless tobacco. Results and Conclusion. The pooled OR for chewing tobacco and risk of oral cancer was 4.7 [3.1-7.1] and for paan with tobacco and risk of oral cancer was 7.1 [4.5-11.1]. The findings of this study suggest a strong causal link between oral cancer and various forms of smokeless tobacco. Public health policies in affected countries should consider SLT specific cessation programs in addition to campaigns and activities incorporated into smoking cessation programs. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32563921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence and outcomes of desmoplastic small round cell tumor: results from the surveillance, epidemiology, and end results database. 结缔组织增生小圆细胞瘤的发病率和预后:来自监测、流行病学和最终结果数据库的结果。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2014-01-01 Epub Date: 2014-11-05 DOI: 10.1155/2014/680126

Christina K Lettieri, Pamela Garcia-Filion, Pooja Hingorani

{"title":"Incidence and outcomes of desmoplastic small round cell tumor: results from the surveillance, epidemiology, and end results database.","authors":"Christina K Lettieri, Pamela Garcia-Filion, Pooja Hingorani","doi":"10.1155/2014/680126","DOIUrl":"https://doi.org/10.1155/2014/680126","url":null,"abstract":"Desmoplastic small round cell tumor (DSRCT) is a rare but highly fatal malignancy. Due to the rarity of this neoplasm, no large population based studies exist. Procedure. This is a retrospective cohort analysis. Incidence rates were calculated based on sex and ethnicity and compared statistically. Gender-, ethnicity-, and treatment- based survival were calculated using the Kaplan-Meier method. Results. A total of 192 cases of DSRCT were identified. Peak incidence age was between 20 and 24 years. Age-adjusted incidence rate for blacks was 0.5 cases/million and for whites was 0.2 cases/million (P = 0.037). There was no statistically significant difference in survival based on gender or ethnicity. When adjusted for age, there was no statistically significant difference in survival amongst patients who received radiation therapy compared to those who did not (HRadj = 0.73; 95% CI 0.49, 1.11). There was a statistically significant survival advantage for patients who received radiation after surgery compared to those who did not (HR 0.49; 95% CI 0.30, 0.79). Conclusion. DSRCT is more common in males and in people of African-American descent. Although overall survival remains poor, radiation therapy following surgery seems to improve outcome in these patients. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/680126","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32843429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 75

Characterization of pediatric acute lymphoblastic leukemia survival patterns by age at diagnosis. 按诊断年龄划分的小儿急性淋巴细胞白血病存活模式。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2014-01-01 Epub Date: 2014-09-17 DOI: 10.1155/2014/865979

Md Jobayer Hossain, Li Xie, Suzanne M McCahan

{"title":"Characterization of pediatric acute lymphoblastic leukemia survival patterns by age at diagnosis.","authors":"Md Jobayer Hossain, Li Xie, Suzanne M McCahan","doi":"10.1155/2014/865979","DOIUrl":"10.1155/2014/865979","url":null,"abstract":"Age at diagnosis is a key prognostic factor in pediatric acute lymphoblastic leukemia (ALL) survivorship. However, literature providing adequate assessment of the survival variability by age at diagnosis is scarce. The aim of this study is to assess the impact of this prognostic factor in pediatric ALL survival. We estimated incidence rate of mortality, 5-year survival rate, Kaplan-Meier survival function, and hazard ratio using the Surveillance Epidemiology and End Results (SEER) data during 1973-2009. There was significant variability in pediatric ALL survival by age at diagnosis. Survival peaked among children diagnosed at 1-4 years and steadily declined among those diagnosed at older ages. Infants (<1 year) had the lowest survivorship. In a multivariable Cox proportional hazard model stratified by year of diagnosis, those diagnosed in age groups 1-4, 5-9, 10-14, and 15-19 years were 82%, 75%, 57%, and 32% less likely to die compared to children diagnosed in infancy, respectively. Age at diagnosis remained to be a crucial determinant of the survival variability of pediatric ALL patients, after adjusting for sex, race, radiation therapy, primary tumor sites, immunophenotype, and year of diagnosis. Further research is warranted to disentangle the effects of age-dependent biological and environmental processes on this association. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32742033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cancer in the elderly. 老年人的癌症。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2014-01-01 Epub Date: 2014-04-30 DOI: 10.1155/2014/872029

Frank Buntinx, Christine Campbell, Marjan van den Akker

{"title":"Cancer in the elderly.","authors":"Frank Buntinx, Christine Campbell, Marjan van den Akker","doi":"10.1155/2014/872029","DOIUrl":"https://doi.org/10.1155/2014/872029","url":null,"abstract":"Part 1 Introduction: sickness and health in old age, R.E.Irvine epidemiology of cancer in the elderly, D.W.Lamont hopes and fears of the elderly cancer patient, I.B.Brewin. Part 2 Principles of management of cancer in the elderly: principles of surgery, Henry Tankel principles of radiotherapy, Thurston Brewin principles of chemotherapy, Craig Lewis, Kaye & Calman terminal care, J.Welsh. Part 3 Complications of cancer in the elderly: metabolic aspects, H.M.Hodkinson paraneoplastic CNS syndromes, Chen-Ya Huang. Part 4 Organs and systems: breast cancer, Allan Langlands bronchus lung tumours, Gordon P.Canning and F.J. Caird Oesophagus, P.T.D. Symonds stomach gastric cancers, Alan Jewkes, Simon Rowley and T.J. & Priestman colon, and rectum and anus, Philip F.Schofield liver, gallbladder, and pancreas, John Chalstrey kidney, ureter and bladder, Philip P.Clark cancer of the prostate, Malcolm A.Bagshaw gynaecological cancer malignancy, L.N.Hudson skin, Rona M.MacKie lymphoma and leukaemia and malignant, John M.Dagg myeloma, J.S.Malpas, Wallace Stewart eye ophthalmic neoplasia, Bertil E.Damato and Foulds malignant disorders of bone, Frank J.Frassica, Lester E.Wold and Franklin H. & Sim head and neck cancer, D.F.N.Harrison brain and spinal cord, David A.Stewart and F.J.Caird.","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/872029","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32380996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 88

Colorectal cancer incidence and mortality disparities in new Mexico. 新墨西哥州结直肠癌发病率和死亡率差异。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2014-01-01 Epub Date: 2014-01-02 DOI: 10.1155/2014/239619

Richard M Hoffman, David K Espey, Robert L Rhyne, Melissa Gonzales, Ashwani Rajput, Shiraz I Mishra, S Noell Stone, Charles L Wiggins

{"title":"Colorectal cancer incidence and mortality disparities in new Mexico.","authors":"Richard M Hoffman, David K Espey, Robert L Rhyne, Melissa Gonzales, Ashwani Rajput, Shiraz I Mishra, S Noell Stone, Charles L Wiggins","doi":"10.1155/2014/239619","DOIUrl":"10.1155/2014/239619","url":null,"abstract":"Background. Previous analyses indicated that New Mexican Hispanics and American Indians (AI) did not experience the declining colorectal cancer (CRC) incidence and mortality rates observed among non-Hispanic whites (NHW). We evaluated more recent data to determine whether racial/ethnic differences persisted. Methods. We used New Mexico Surveillance Epidemiology and End Results data from 1995 to 2009 to calculate age-specific incidence rates and age-adjusted incidence rates overall and by tumor stage. We calculated mortality rates using National Center for Health Statistics' data. We used joinpoint regression to determine annual percentage change (APC) in age-adjusted incidence rates. Analyses were stratified by race/ethnicity and gender. Results. Incidence rates continued declining in NHW (APC -1.45% men, -1.06% women), while nonsignificantly increasing for AI (1.67% men, 1.26% women) and Hispanic women (0.24%). The APC initially increased in Hispanic men through 2001 (3.33%, P = 0.06), before declining (-3.10%, P = 0.003). Incidence rates declined in NHW and Hispanics aged 75 and older. Incidence rates for distant-stage cancer remained stable for all groups. Mortality rates declined significantly in NHW and Hispanics. Conclusions. Racial/ethnic disparities in CRC persist in New Mexico. Incidence differences could be related to risk factors or access to screening; mortality differences could be due to patterns of care for screening or treatment. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/239619","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32115235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Associations of census-tract poverty with subsite-specific colorectal cancer incidence rates and stage of disease at diagnosis in the United States. 美国人口普查区贫困与特定地区结直肠癌发病率和诊断时疾病阶段的关系。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2014-01-01 Epub Date: 2014-08-03 DOI: 10.1155/2014/823484

Kevin A Henry, Recinda L Sherman, Kaila McDonald, Christopher J Johnson, Ge Lin, Antoinette M Stroup, Francis P Boscoe

{"title":"Associations of census-tract poverty with subsite-specific colorectal cancer incidence rates and stage of disease at diagnosis in the United States.","authors":"Kevin A Henry, Recinda L Sherman, Kaila McDonald, Christopher J Johnson, Ge Lin, Antoinette M Stroup, Francis P Boscoe","doi":"10.1155/2014/823484","DOIUrl":"10.1155/2014/823484","url":null,"abstract":"Background. It remains unclear whether neighborhood poverty contributes to differences in subsite-specific colorectal cancer (CRC) incidence. We examined associations between census-tract poverty and CRC incidence and stage by anatomic subsite and race/ethnicity. Methods. CRC cases diagnosed between 2005 and 2009 from 15 states and Los Angeles County (N = 278,097) were assigned to 1 of 4 groups based on census-tract poverty. Age-adjusted and stage-specific CRC incidence rates (IRs) and incidence rate ratios (IRRs) were calculated. Analyses were stratified by subsite (proximal, distal, and rectum), sex, race/ethnicity, and poverty. Results. Compared to the lowest poverty areas, CRC IRs were significantly higher in the most impoverished areas for men (IRR = 1.14 95% CI 1.12-1.17) and women (IRR = 1.06 95% CI 1.05-1.08). Rate differences between high and low poverty were strongest for distal colon (male IRR = 1.24 95% CI 1.20-1.28; female IRR = 1.14 95% CI 1.10-1.18) and weakest for proximal colon. These rate differences were significant for non-Hispanic whites and blacks and for Asian/Pacific Islander men. Inverse associations between poverty and IRs of all CRC and proximal colon were found for Hispanics. Late-to-early stage CRC IRRs increased monotonically with increasing poverty for all race/ethnicity groups. Conclusion. There are differences in subsite-specific CRC incidence by poverty, but associations were moderated by race/ethnicity. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32620692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A population-based study of childhood cancer survivors' body mass index. 一项关于儿童癌症幸存者体重指数的人群研究。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2014-01-01 Epub Date: 2014-01-09 DOI: 10.1155/2014/531958

Echo L Warner, Mark Fluchel, Jennifer Wright, Carol Sweeney, Kenneth M Boucher, Alison Fraser, Ken R Smith, Antoinette M Stroup, Anita Y Kinney, Anne C Kirchhoff

{"title":"A population-based study of childhood cancer survivors' body mass index.","authors":"Echo L Warner, Mark Fluchel, Jennifer Wright, Carol Sweeney, Kenneth M Boucher, Alison Fraser, Ken R Smith, Antoinette M Stroup, Anita Y Kinney, Anne C Kirchhoff","doi":"10.1155/2014/531958","DOIUrl":"10.1155/2014/531958","url":null,"abstract":"Background. Population-based studies are needed to estimate the prevalence of underweight or overweight/obese childhood cancer survivors. Procedure. Adult survivors (diagnosed ≤20 years) were identified from the linked Utah Cancer Registry and Utah Population Database. We included survivors currently aged ≥20 years and ≥5 years from diagnosis (N = 1060), and a comparison cohort selected on birth year and sex (N = 5410). BMI was calculated from driver license data available from 2000 to 2010. Multivariable generalized linear regression models were used to calculate prevalence relative risks (RR) and 95% confidence intervals (95% CI) of BMI outcomes for survivors and the comparison cohort. Results. Average time since diagnosis was 18.5 years (SD = 7.8), and mean age at BMI for both groups was 30.5 (survivors SD = 7.7, comparison SD = 8.0). Considering all diagnoses, survivors were not at higher risk for being underweight or overweight/obese than the comparison. Male central nervous system tumor survivors were overweight (RR = 1.12, 95% CI 1.01-1.23) more often than the comparison. Female survivors, who were diagnosed at age 10 and under, had a 10% higher risk of being obese than survivors diagnosed at ages 16-20 (P < 0.05). Conclusion. While certain groups of childhood cancer survivors are at risk for being overweight/obese, in general they do not differ from population estimates. ","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32115236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Worldwide increasing incidence of thyroid cancer: update on epidemiology and risk factors. 世界范围内甲状腺癌发病率的增加:流行病学和危险因素的最新情况。

IF 1.8

Journal of Cancer Epidemiology Pub Date : 2013-01-01 Epub Date: 2013-05-07 DOI: 10.1155/2013/965212

Gabriella Pellegriti, Francesco Frasca, Concetto Regalbuto, Sebastiano Squatrito, Riccardo Vigneri

{"title":"Worldwide increasing incidence of thyroid cancer: update on epidemiology and risk factors.","authors":"Gabriella Pellegriti, Francesco Frasca, Concetto Regalbuto, Sebastiano Squatrito, Riccardo Vigneri","doi":"10.1155/2013/965212","DOIUrl":"https://doi.org/10.1155/2013/965212","url":null,"abstract":"Background. In the last decades, thyroid cancer incidence has continuously and sharply increased all over the world. This review analyzes the possible reasons of this increase. Summary. Many experts believe that the increased incidence of thyroid cancer is apparent, because of the increased detection of small cancers in the preclinical stage. However, a true increase is also possible, as suggested by the observation that large tumors have also increased and gender differences and birth cohort effects are present. Moreover, thyroid cancer mortality, in spite of earlier diagnosis and better treatment, has not decreased but is rather increasing. Therefore, some environmental carcinogens in the industrialized lifestyle may have specifically affected the thyroid. Among potential carcinogens, the increased exposure to medical radiations is the most likely risk factor. Other factors specific for the thyroid like increased iodine intake and increased prevalence of chronic autoimmune thyroiditis cannot be excluded, while other factors like the increasing prevalence of obesity are not specific for the thyroid. Conclusions. The increased incidence of thyroid cancer is most likely due to a combination of an apparent increase due to more sensitive diagnostic procedures and of a true increase, a possible consequence of increased population exposure to radiation and to other still unrecognized carcinogens.","PeriodicalId":15366,"journal":{"name":"Journal of Cancer Epidemiology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2013/965212","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31575543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1091