{"title":"Nagapashana Pishti - A Potent Cardio Tonic","authors":"Vidya Amr, Chaitra Lv, Jeevesh Kb","doi":"10.21760/jaims.5.5.32","DOIUrl":"https://doi.org/10.21760/jaims.5.5.32","url":null,"abstract":"Nagapashana (Serpentine), a hydrous silicate of Magnesium (Mg6 (Sio10) OH8), is an important mineral drug used in Ayurveda, often in the form of Pishti (fine powder of Nagapashana). It is a Hrudya Dravya (cardiotonic). It is particularly indicated in Hrud Dourbalyaa, a condition associated with weakness of cardiac muscles. Cardiovascular disease is a leading cause of death in developed and developing countries. The present study was conducted to evaluate the cardio tonic activity of Nagapashana Pishti on Wistar rats. In the in-vivo study, Doxorubicin (2mg/kg) for 7 days was used to induce cardiac damage and the cardio tonic effect of Nagapashana Pishti at a dose of 150 and 300 mg/kg.b.w, was compared with standard drug Digoxin. Biochemical assays like serum glutamic oxaloacetic transaminase (SGOT), Serum glutamic pyruvic transaminase (SGPT), lactate dehydrogenase (LDH), Total Cholesterol (TC), Triglyceride (TG) and Creatine kinase Monoenzyme B (CKMB) were done together with histopathology of heart tissue and ECG analysis. The in-vivo study revealed that Nagapashana Pishti (300mg/kg) was relatively more effective due to decreased QT and ST interval in ECG, significantly reduced levels of serum CKMB, SGOT, SGPT, TC and LDH and improvement in myocardial tissue.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126942668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmaceutico - Analytical study of Durvadya Taila and its conversion into cream","authors":"Baban Rathod, Gangaprasad R. Asore, S. Sankpal","doi":"10.21760/jaims.5.5.33","DOIUrl":"https://doi.org/10.21760/jaims.5.5.33","url":null,"abstract":"Durvadya Taila is medicated oil used in Ayurveda for Kacchu, Vicharchika and Pama (types of Skin diseases) which is caused by vitiated Kapha or Pitta Dosha. Durva is one of the classical drugs of herbal origin, for the management of different disease conditions. The aim of the present study is to do physico-chemical standards for above Durvadya Taila and its conversion into Durvadya Taila Cream. These two formulations have a special importance from pharmaceutical point of view when compared to usual Taila or cream. In present article, we are trying to study analytical results of Durvadya Taila w.s.r. to Durvadya Taila cream. The skin constitutes a major part of the body and serves as a dividing line between the individual and his environment. In the Ayurvedic classics, Bahir Parimarjana means, the medicine intended for external use only. For that purpose, in Ayurveda different forms of external applications are described for the convenience of treatment of different diseases. They are Lepa, Udvartana, Upanaha, Abhyanga, Malahara etc. Without defining creams under Panchavidha Kashaya Kalpana, we can correlate Cream preparation with Lepa or Malahara Kalpana. Creams are those emulsions, which are either oil in-water or water-in-oil type. Durvadya Taila is medicated oil used in Ayurveda for Kacchu, Vicharchika and Pama which comes under Kushtha Rogadhikar.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"134 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122427125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A comparative clinical study to access the role of Basti and Virechana Karma followed by Rasayana in post menopausal Asthikshaya (Osteoporosis)","authors":"D. S. Patil, S. Prashantha","doi":"10.21760/jaims.5.5.12","DOIUrl":"https://doi.org/10.21760/jaims.5.5.12","url":null,"abstract":"Rajonivrutti condition manifests in the end phase of Jarawastha; but its Samprapti begins from the Sandhikala of Madhyamawastha and Jarawastha due to Vatavruddi in womens reaching Rajonivrutti. Postmenopausal Asthikshaya is a disabling disease, which renders women a bedridden life. Here 40 subjects diagnosed with postmenopausal Asthikshaya fulfilling the inclusion criteria were selected for the study and randomly categorized intp two groups as group A and group B each consisting of 20 subjects. Group A received Amapachana with Hinguvachadivati, Yastimadhu Siddha Ksheerabasti administered in Yoga Basti schedule followed by Tritiyatriphala Rasayana. Group B received Amapachana with Hinguvachadivati, Sadhyosnehapana with Amrita Ghrita, Sarvanga Abyanga with Murchita Tilataila followed by Sarvanga Swedana and Sneha Virechana was admistered with Eranda Taila followed by Tritiyatriphala Rasayana was given. Tritiya Triphala Rasayana selected for the present study by adapting all the general principles of prevention and management of Asthikshaya and as it is a well known Rasayana.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125063826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmaceutico analytical study of Ashwagandha Ghrita","authors":"Amrita Raveendran, S. Rao, S. Vikram","doi":"10.21760/jaims.5.5.31","DOIUrl":"https://doi.org/10.21760/jaims.5.5.31","url":null,"abstract":"Ashwagandha (Withania somnifera (L) Family - Solanaceae) known as Indian ginseng is an effective immunomodulator, aphrodisiac, sedative and adaptogen. Ashwagandha Ghrita is a ghee based Ayurvedic formulation which is available in the market, but Ashwagandha Ghrita containing Rasasindura and Tamra Bhasma along with Ashwagandha and Musta Churna is also mentioned in classical text which many of us are not aware of. As we all know that the action of Rasaushadhis are quick and require very less dose the one mentioned by Vagbhatacharya (author of Rasaratnasamuchaya) is the need of the hour for the immunomodulation. The current trend in applied instrumental medical research encourages good medical practice, clinical and research based drug analysis. The main aim of analytical study is to find out working standards for the formulations and safe use of therapeutics.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130058441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A study on the effectivness of Guggulu based Karaveera Ksharasutra in comparison with Apamarga Ksharasutra in the management of Shalyaja Nadivrana w.s.r. to Pilonidal Sinus","authors":"Monisha C. J., Narmada M.G.","doi":"10.21760/jaims.5.5.2","DOIUrl":"https://doi.org/10.21760/jaims.5.5.2","url":null,"abstract":"Shalyaja Nadivrana is of Agantuja Vranabedha. Nidana Panchaka is described in Sushruta Samhita Nidhana and Chikitsa Sthana. Presence of “Shalya” is hindering factor for healing. Management of Nadivrana includes Ksharasutra ligation. Pilonidal sinus is acquired sinus occurring in young hirsute men’s commonly seen at intergluteal cleft caused by hair penetrating the skin resulting in Pilonidal abscess which gradually forms into sinus with presence of “Hair” leading to wound discharge. It is one of the troublesome diseases which doesn’t respond to medical management till hair is evacuated. The current surgical procedures adopted have surgical risk and recurrence as well. Guggulu and Karaveera is abundantly available and can be preserved easily for long time. Hence can be used as substitute to the standard Ksharasutra. The present study “A study on the effectiveness of Guggulu based Karaveera Ksharasutra in comparison with Apamarga Ksharasutra in the management of Shalyaja Nadivrana w.s.r. to Pilonidal Sinus”was conducted in SJIIM hospital Bengaluru with 40 patients randomly allotted into 2 groups namely - Group A and Group B. Assessment was done based on subjective parameters like (pain, discharge) and objective parameters like (length of tract, tenderness). Observation was done before treatment and on every 7th day till tract is completely cut and healed. Assessment of Pain, discharge, length of tract and tenderness in Group-A showed 100%, 100%, 100% and 100% improvement and in Group-B showed 97.92%, 100%, 100% and 100% respectively. UCT in Group-A is 6.58% and Group-B is 9.15%. Overall results of group A and B is 100% and 99.5% respectively. Statistical analysis revealed that the effectiveness of Guggulu based Karaveera Ksharasutra in Shalyaja Nadivrana is as effective as Apamarga Ksharasutra w.s.r. to pilonidal sinus.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122383818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A clinical study to evaluate the efficacy of Murivenna application on Episiotomy Wound","authors":"K. P, S. Patil","doi":"10.21760/jaims.5.5.8","DOIUrl":"https://doi.org/10.21760/jaims.5.5.8","url":null,"abstract":"A surgically planned incision on the perineum and the posterior vaginal wall during the second stage of labor is called episiotomy (Perineotomy). It is in fact an inflicted second-degree perineal injury. It is the most common obstetric operation performed. This is done to enlarge the vaginal introitus to facilitate easy and safe delivery of the fetus and to minimize overstretching and rupture of the perineal muscles and fascia thus to reduce the stress and strain on the fetal head. This wound of episiotomy is associated with a delicate area of the female with immense pain and discomfort and seeks appropriate medical care and attention. If ignored, it may lead to puerperal wound infections and delayed healing that can interfere mother-infant interaction, lactation and prolonged hospital stay. Episiotomy wound care should be start immediately after suturing the wound in order to reduce pain and inflammation. The surgical wound of episiotomy can be considered as Sadyo Vrana. Different treatment modalities have been told in Ayurveda for Vrana Chikitsa. Drugs having Shodhana and Ropana qualities are essential for healing. In this research study total 30 patients were registered and treated in two groups, group A with application of Jatyadi Taila on episiotomy wound after Ushna Jala Parisheka as a standard control group and Group B with application of Murivenna after Ushna Jala Parisheka as a trial group. Encouraging results were observed in Murivenna. Study emerges that Murivenna possess better pain relieving and tenderness diminishing properties.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"140 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123292686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmaceutico analytical study of Mukha Kanthikara Lepa and development of its new dosage form into Cream and Gel","authors":"Amaresha Jeedi, S. Yadav, Surekha S. Medikeri","doi":"10.21760/jaims.5.5.22","DOIUrl":"https://doi.org/10.21760/jaims.5.5.22","url":null,"abstract":"The need for cosmetics is seen from very ancient days; peoples were using variety of cosmetic products both for curative purpose as well as enhancing beauty. Mukhakantikara Lepa is a polyherbal formulation mentioned in Sharandhara Samhita in the form of Churna, which is extensively used to enhance skin complexion. In present time, the difficulty of portability, application, removal and shelf life of the Churna is a great challenge to Lepa form though being effective. Here arises a need for newer dosage form. Creams and gels are semisolid preparations which may be defined as topical products intended for application on skin or accessible mucous membrane to provide localised and sometimes systemic effects at the site of application. This dosage forms are more stable, easy to handle, easy to apply and remove. Hence, modification of Mukhakatikara Lepa into Cream and Gel can be a better idea to overcome the shortcoming of Lepa form.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115755491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Baban Rathod, Gangaprasad R. Asore, Kanchan Bhawarlal Suthar
{"title":"Pharmaceutical and Analytical Study of Ashwagandha Paak","authors":"Baban Rathod, Gangaprasad R. Asore, Kanchan Bhawarlal Suthar","doi":"10.21760/jaims.5.5.35","DOIUrl":"https://doi.org/10.21760/jaims.5.5.35","url":null,"abstract":"Avaleha / Paak Kalpana is Upkalpana of Kwatha which is commonly prepared nowadays and useful in various disorders. Because of simple preparation method, better palatability and longer shelf life it is gaining popularity on a large scale. Ashwagandha Paak has been prepared as per reference of Bharat Bhaishajya Ratnakar. After preparation it has been studied for its quality and pharmaceutical parameters.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130585938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sachin S. Sheth, Gangaprasad R. Asore, Kiran Sudhakar Darade
{"title":"Pharmaceutico-Analytical study of Karanjadi Taila and its conversion into cream","authors":"Sachin S. Sheth, Gangaprasad R. Asore, Kiran Sudhakar Darade","doi":"10.21760/jaims.5.5.34","DOIUrl":"https://doi.org/10.21760/jaims.5.5.34","url":null,"abstract":"Karanjadi Taila is medicated oil used in Ayurveda for Indralupta (Alopecia). Indralupta comes under Kshudra Roga which is characterized by loss of hair it can be correlated with Alopecia areata which is having chief complaint of hair loss on body especially on scalp. The aim of the present study is to do physic-chemical standards for the above Taila and its conversion into Karanjadi Taila cream. These two formulations have a special importance from pharmaceutical point of view when compared to usual Tailas or cream. In present article, we are trying to study analytical results of Karanjadi Taila w.s.r. to Karanjadi Taila cream.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115677738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patil Ashwini Shrimant, P. Rawal, Sunita Shiraguppi, Shrishail. S. Pujeri
{"title":"A comparative clinical study to evaluate the effect of Indrayavadi Yoga and Bhoomyamalaki Choorna in the management of Asrigdara w.s.r. to Puberty Menorrhagia","authors":"Patil Ashwini Shrimant, P. Rawal, Sunita Shiraguppi, Shrishail. S. Pujeri","doi":"10.21760/jaims.5.5.4","DOIUrl":"https://doi.org/10.21760/jaims.5.5.4","url":null,"abstract":"A normal menstruation denotes a healthy state of female reproductive system. If the menstrual bleeding is abnormally excessive, prolonged and is associated with pain, it indicates some pathology. The abnormal menstrual cycle not only disturbs the general health, it also disturbs routine work schedule of the woman and her entire family. There is no direct reference of Puberty menorrhagia in classics. Puberty menorrhagia is defined as excessive bleeding occurring between menarche to 19 years of age. Anovulatory bleeding with irregular shedding of endometrium is the cause for puberty Menorrhagia which can be effectively tackled with the help of herbal drugs which contains hemostatic action. Asrigdara mainly due to vitiation of Vata and Pitta Doshas, hence the treatment should be based on use of drugs which are having predominance of Kashayarasa and Pitta-Vatashamaka properties and Stambhan action. Thus selected drugs are Indrayavadi Yoga and Bhoomyamalaki Choorna possess Vata-Pitta Shamaka and Raktastambhaka. This research work is comparative clinical study. 40 patients presenting with Pratyatma Lakshana of Asrigdara were randomly selected and divided into 2 groups of 20 patients each. Group A were given Indrayavadi Yoga and group B were given Bhoomyamalaki Choorna for a period of 2 menstrual cycle and two follow up during treatment and one follow up after treatment. After the completion of clinical trial, it was found that Bhoomyamalaki Choorna which was group B is more effective than group A. The overall effect in group A and Group B, both the groups shown excellent response, but when comparing all the parameters Bhoomyamalaki Choorna shown more significant response than Indrayavadi Yoga. Trial drug is a better remedy for Asrigdara. It has no side effect, cost effective.","PeriodicalId":153289,"journal":{"name":"Journal of Ayurveda and Integrated Medical Sciences (JAIMS)","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115305400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}