Journal of Child Neurology最新文献

{"title":"Pediatric Seizure First-Aid Content on Social Media: Accuracy, Educational Quality, and Engagement Across Platforms.","authors":"Beatriz De Faria Sousa, Manal Imran, Richard Reyes, Alexis Carmona, Randy Pando, Katherine Semidey","doi":"10.1177/08830738261472020","DOIUrl":"https://doi.org/10.1177/08830738261472020","url":null,"abstract":"<p><p>Caregivers frequently turn to social media for pediatric seizure guidance, yet it remains unclear whether high-reach content aligns with established first-aid recommendations. We conducted a cross-sectional analysis of 150 high-view seizure-related videos across TikTok, Instagram, and YouTube (50 per platform). Videos were coded for creator type, accuracy, emergency department (ED)/911 guidance, and Global Quality Score (0-5). Overall accuracy was high (88.7%); however, only 49.3% included ED/911 guidance. Educational quality differed by creator type (<i>F</i> = 6.15, <i>P</i> < .001), with Health Care Professional videos demonstrating higher Global Quality Scores than Parent/Caregiver and Influencer content. Parent/Caregiver videos achieved the highest mean views (2.88 million), although median engagement was substantially lower than that of Health Care Professional and Health Organization videos, indicating that the higher mean reach was driven by a small number of viral caregiver posts rather than consistently higher engagement. Accuracy and quality were not independently associated with views. These findings suggest that engagement dynamics, rather than educational completeness, drive reach, underscoring the importance of clinician presence in digital seizure education.</p>","PeriodicalId":15319,"journal":{"name":"Journal of Child Neurology","volume":" ","pages":"8830738261472020"},"PeriodicalIF":1.6,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148684923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges and Innovations in Equitable EEG for Patients with Coarse, Dense, and Curly Hair.","authors":"Jasmine A Kwasa, Arnelle Etienne, Christina Patterson, Pulkit Grover","doi":"10.1177/08830738261467849","DOIUrl":"10.1177/08830738261467849","url":null,"abstract":"","PeriodicalId":15319,"journal":{"name":"Journal of Child Neurology","volume":" ","pages":"8830738261467849"},"PeriodicalIF":1.6,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13454968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148684836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, Regional, and National Epidemiology of Attention Deficit Hyperactivity Disorder in Children From 1990 to 2021, with Projections to 2051.","authors":"Jue Hu, Jie-Yi Wang, Yan Zhao, Xiao-Bo Xuan, Jing-Ying Ma, Jian Chen","doi":"10.1177/08830738261464418","DOIUrl":"https://doi.org/10.1177/08830738261464418","url":null,"abstract":"&lt;p&gt;&lt;p&gt;BackgroundAttention deficit hyperactivity disorder (ADHD) in children is a common neuropsychiatric disease in the world, which has a significant impact on children, families, and society.AimsThis study aims to examine the trends in ADHD incidence, prevalence, and disability-adjusted life years (DALYs) among children to guide preventive measures.MethodThis cross-sectional analysis used data from the Global Burden of Diseases (GBD) spanning 1990 to 2021 across 204 nations and territories. Children diagnosed with ADHD aged ≤14 years were incorporated into the analysis. The main outcome measures include incidence, prevalence, DALYs, case changes, and estimated annual percentage changes (EAPCs). The trends were categorized by location, nation, age, sex, and Socio-Demographic Index (SDI). Meanwhile, an age-period-cohort (APC) model is used to estimate net drifts, local drifts, longitudinal age curves, and the period relative risks. Bayesian APC (BAPC) models were used to anticipate the global burden of ADHD from 2022 to 2051. Data were analyzed from September 10, 2024, to September 25, 2024.ResultsA total of 33 429 324 children (73.14% male; 26.86% female) were included in the analysis. There were 4 111 621 children with ADHD cases globally in 2021. From 1990 to 2021, pediatric ADHD cases rose 9.92% (95% uncertainty interval [UI], 7.13%-13.16%). Over the past 32 years, the global incidence rate decreased from 215.08 (95% UI, 146.23-314.58) to 204.37 (95% UI, 137.94-295.99), whereas prevalent cases increased from 29 564 63 to 33 429 32. DALYs increased from 362 607 to 410 706, with the middle-SDI region having the highest incidence and DALY rate in 2021. Incidence increased most in Western Europe (EAPC, 0.50%), whereas prevalence increased most rapidly in South Asia (EAPC, 0.33%). In 2021, Australia had the highest national incidence (638.35), prevalence (5295.68), and DALYs (65.13) among 204 nations. High-SDI regions had the highest net drift in both incidence rate and prevalence rate (0.21% for each). APC analysis showed that the burden of ADHD exhibited significant age, period, and cohort dependencies, with notable sex and regional heterogeneity. Incidence and prevalence were significantly higher in males than females, although the gender gap has recently narrowed (eg, incidence rate ratio in 2019.5: male 0.97, female 0.96). Furthermore, incidence rates in high-SDI regions worsened over time and across birth cohorts. BAPC model predicts that ADHD incidence will continue to rise, reaching 247.68 incidence rate by 2051 and 4 468 925 incident cases. The number of prevalent cases is projected to reach 25 357 194, and the DALY rate will rise to 23.93.ConclusionsChildhood ADHD represents a growing global public health challenge, with projected increases in incidence, prevalence, and DALYs, particularly in high-middle-SDI regions. Concurrently, DALY rates are rising most rapidly in low-SDI areas. Enhanced understanding of the epidemiology of childhood","PeriodicalId":15319,"journal":{"name":"Journal of Child Neurology","volume":" ","pages":"8830738261464418"},"PeriodicalIF":1.6,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148678836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Migraine on School Attendance and Psychosocial Functioning in Children and Adolescents: A Cross-sectional Study.","authors":"Halil Celik, Suleyman Sahin, Mehmet Alci, Ahmet Sami Guven","doi":"10.1177/08830738261469384","DOIUrl":"https://doi.org/10.1177/08830738261469384","url":null,"abstract":"<p><p>ObjectiveThis study aimed to evaluate the frequency of school absenteeism and associated clinical, sociodemographic, and psychosocial factors in children, adolescents diagnosed with migraine.MethodsThis cross-sectional, descriptive study included 70 pediatric migraine patients (aged 12-17 years; mean age: 14.8 ± 1.3 years) followed at Necmettin Erbakan University Pediatric Neurology Outpatient Clinic. Participants were diagnosed according to the International Classification of Headache Disorders, 3rd Edition (ICHD-3) criteria. Data were collected via a structured 12-item questionnaire covering demographic characteristics, clinical migraine features, school absenteeism duration, academic impact, parental work loss, and teacher awareness. Statistical analyses included χ², Mann-Whitney <i>U</i>, and multivariate logistic regression tests.ResultsThe majority of patients were female (62.9%) and in high school (82.9%). Migraine without aura was the predominant subtype (91.4%). The mean school absenteeism over the preceding year was 4.3 ± 2.4 days. Patients with frequent attacks (>1/mo) had significantly longer absenteeism compared with infrequent attackers (5.1 vs 3.3 days; <i>P</i> = .001). Academic decline was reported by 11.4% of patients and was associated with significantly higher absenteeism (7.4 vs 3.9 days; <i>P</i> = .001). Only 22.9% of patients received prophylactic treatment. Parental work loss was universal (100%; mean 2.5 ± 1.1 days). Teacher awareness of migraine diagnosis was absent in all cases (0%).ConclusionMigraine imposes a significant multidimensional burden on children's educational life, with attack frequency being the primary driver of absenteeism. The complete lack of teacher awareness and high rates of parental work loss underscore critical deficiencies in school-health care collaboration. Multidisciplinary strategies integrating optimized prophylaxis, school-based awareness programs, and individualized health plans are urgently needed.</p>","PeriodicalId":15319,"journal":{"name":"Journal of Child Neurology","volume":" ","pages":"8830738261469384"},"PeriodicalIF":1.6,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148678871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive and Developmental Neuroscience in Nigeria: Challenges, Advances, and Opportunities.","authors":"Ayobami Oyetunji Alabi, Nicholas Aderinto, Israel Charles Abraham, Gbolahan Olatunji, Emmanuel Kokori, Chinonyelum Emmanuel Agbo, Tejiri Napoleon, John Ehi Aboje, Faith Taiwo Oladipo, Mariam Tolulope Edun, Patrick Ashinze, Eno Abasi Sunday, Faisal Hamed Aljamea","doi":"10.1177/08830738261470592","DOIUrl":"https://doi.org/10.1177/08830738261470592","url":null,"abstract":"<p><p>Cognitive and developmental neuroscience in Nigeria faces a range of challenges, including limited research infrastructure, insufficient awareness, and cultural barriers that hinder early diagnosis and intervention for neurodevelopmental disorders (NDDs). Despite these obstacles, significant progress has been made through collaborations with international organizations such as the International Brain Research Organization-Africa Regional Committee (IBRO-ARC), International Society for Neurochemistry (ISN), and The World Academy of Sciences (TWAS), which have provided crucial funding and mentorship to Nigerian neuroscientists. These partnerships have enabled access to advanced research methodologies and fostered knowledge exchange within the African context, particularly through initiatives like the African Brain and Cognitive Development Network (AfriBCD). The impact of maternal and childhood infections, including malaria and congenital viruses, on neurodevelopment highlights the need for targeted public health measures. This article reviews the current state of cognitive and developmental neuroscience in Nigeria, focusing on ongoing research efforts, key challenges, and opportunities for future growth. Strengthening local capacity, expanding sustainable funding opportunities, and facilitating the translation of research into clinical practice are critical steps toward improving the management of neurodevelopmental disorders (NDDs) in Nigeria and enhancing long-term neurodevelopmental outcomes.</p>","PeriodicalId":15319,"journal":{"name":"Journal of Child Neurology","volume":" ","pages":"8830738261470592"},"PeriodicalIF":1.6,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148678912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: Effect of DBS in a Patient With Cerebellar Atrophy.","authors":"Amanda K Salisbury, Anna L Brucker, Aleksandra Zakharova, Seyyed Alireza Seyyed Mousavi, Jennifer Maclean, Joffre Olaya, Mark A Liker, Terence D Sanger","doi":"10.1177/08830738261469386","DOIUrl":"https://doi.org/10.1177/08830738261469386","url":null,"abstract":"<p><p>ObjectiveThe aim of this study is to present a case report of deep brain stimulation (DBS) in the globus pallidus internus (GPi) and ventral anterior nucleus of the thalamus (VA) in a patient with dystonic tremor due to progressive cerebellar atrophy of unknown etiology.BackgroundAlthough DBS has been shown to be effective in disorders of basal ganglia origin, its use for cerebellar origin disorders remains less understood. This case study presents a patient with dystonic tremor, ataxia, and psychiatric symptoms associated with cerebellar atrophy of unknown etiology. The patient was treated with DBS implantation in GPi and VA. Targets were selected using clinical observation and data obtained from stereoelectroencephalography (sEEG) depth electrode implantation and subsequent observation in an inpatient Neuromodulation Monitoring Unit (NMU).MethodsPreoperative and 1-year postoperative scores were examined to determine improvement in symptoms using Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS), Barry Albright Dystonia Scale (BADS), and Scale for Assessment and Rating of Ataxia (SARA).ResultsAn improvement in movement symptomatology was seen 1 year after permanent electrode implantation and programming using the movement scales (BFMDRS movement preprocedure 15.5, postprocedure 8; BFMDRS disability preprocedure 13, postprocedure 8; BADS preprocedure 14, postprocedure 7; SARA preprocedure 20.5, postprocedure 14.5).ConclusionsDBS can have beneficial effects on multiple symptoms associated with cerebellar degeneration. We cannot exclude the possibility of other neurologic deficits in this patient, and thus the effect of DBS could be mediated through multiple mechanisms. This case report suggests the need for further exploration of the role of DBS in cerebellar-origin disorders.</p>","PeriodicalId":15319,"journal":{"name":"Journal of Child Neurology","volume":" ","pages":"8830738261469386"},"PeriodicalIF":1.6,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148664014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Paradox: The Role of TNF-α Inhibitors in the Emergence of FLAIR-Hyperintense Lesions and Seizures in Anti-MOG Encephalitis - A Case-Based Review.","authors":"Adnan Deniz, Hafize Emine Sönmez","doi":"10.1177/08830738251401035","DOIUrl":"10.1177/08830738251401035","url":null,"abstract":"<p><p>Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) encompasses a spectrum of demyelinating disorders of the central nervous system, including a rare subtype known as FLAMES (FLAIR-hyperintense Lesions in Anti-MOG-associated Encephalitis with Seizures). FLAMES typically presents with unilateral cortical lesions, seizures, and elevated inflammatory markers in cerebrospinal fluid (CSF). Although the pathophysiology remains incompletely understood, recent reports have suggested potential immunologic triggers, including biologic agents. Herein, we present a case of a 17-year-old male adolescent with long-standing psoriasis, treated with the tumor necrosis factor α (TNF-α) inhibitor adalimumab, who developed FLAMES. The patient initially presented with focal seizures and severe headache, followed by neuropsychiatric symptoms and magnetic resonance imaging (MRI) findings consistent with cortical fluid-attenuated inversion recovery (FLAIR) hyperintensities. Diagnostic workup revealed positive anti-MOG antibodies, elevated CSF protein, and pleocytosis, whereas infectious etiologies were excluded. High-dose corticosteroids led to partial improvement, but behavioral disturbances and steroid-induced psychiatric effects necessitated a switch to intravenous immunoglobulin, which resulted in further clinical recovery. Due to the uncertain safety of other TNF-α inhibitors in similar contexts, alternative psoriasis treatment was considered. This case emphasizes the importance of recognizing FLAMES as a potential adverse event associated with TNF-α inhibitors and supports the need for individualized immunotherapy. Clinicians should be vigilant when patients receiving biologics present with new-onset seizures and cortical lesions. Further research is needed to elucidate the underlying mechanisms linking TNF-α inhibitor therapy and MOGAD.</p>","PeriodicalId":15319,"journal":{"name":"Journal of Child Neurology","volume":" ","pages":"1030-1037"},"PeriodicalIF":1.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145774744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, Regional, and National Burden of Meningitis in Children Aged 0-14 Years From 1990 to 2021: Trends and Disparities Based on the Global Burden of Disease Study.","authors":"Shuangjian Yang, Changqin Pu, Congcong Deng, Xuexue Bai, Chenxin Tian, Wentai Zhang, Renzhi Wang, Mengqi Chang, Ming Feng","doi":"10.1177/08830738251399249","DOIUrl":"10.1177/08830738251399249","url":null,"abstract":"<p><p>BackgroundMeningitis remains a major cause of morbidity and mortality among children aged 0-14 years, especially in low- and middle-income countries, despite global advances in vaccines and health care.MethodsBased on Global Burden of Disease (GBD) 2021 data, we assessed meningitis-related prevalence, mortality, and disability-adjusted life years (DALYs) in children aged 0-14 across 204 countries from 1990 to 2021, stratified by age, sex, region, and Socio-demographic Index (SDI). Trends were evaluated using Estimated Annual Percentage Change.ResultsFrom 1990 to 2021, global prevalence, deaths, and DALYs declined by 52.0%, 69.2%, and 69.1%, respectively. The highest burden in 2021 was observed in Sub-Saharan Africa and South Asia. Disease burden showed wide geographic variation and was inversely correlated with SDI. Leading attributable risks included malnutrition and behavioral factors.ConclusionsAlthough meningitis burden has decreased globally, regional disparities persist. Sustained vaccination, health system strengthening, and targeted interventions in high-burden areas remain critical to reducing preventable childhood deaths and disabilities.</p>","PeriodicalId":15319,"journal":{"name":"Journal of Child Neurology","volume":" ","pages":"949-960"},"PeriodicalIF":1.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145668775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrophysiological and Quantitative Fingerprints of Landau-Kleffner Syndrome.","authors":"Akshaya Rathin Sivaji, Jun Park","doi":"10.1177/08830738261422852","DOIUrl":"10.1177/08830738261422852","url":null,"abstract":"","PeriodicalId":15319,"journal":{"name":"Journal of Child Neurology","volume":" ","pages":"1006-1010"},"PeriodicalIF":1.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147344387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proceedings of the 49th Annual Southern Pediatric Neurology Society Meeting.","authors":"","doi":"10.1177/08830738261444830","DOIUrl":"10.1177/08830738261444830","url":null,"abstract":"","PeriodicalId":15319,"journal":{"name":"Journal of Child Neurology","volume":" ","pages":"1072-1079"},"PeriodicalIF":1.6,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}