Journal of Child Neurology最新文献

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Clinical Impact and Safety Profile of Intravenous Lacosamide Administration as Adjunctive Therapy for Neonatal Seizures. 静脉注射拉科酰胺作为新生儿癫痫发作辅助疗法的临床影响和安全性简介

IF 2 4区医学

Journal of Child Neurology Pub Date : 2024-11-14 DOI: 10.1177/08830738241296177

C Cortes-Ledesma, E Arias-Vivas, G Ruiz-Ocaña de Las Cuevas, E Santana-Cabrera, A Garcia-Ron

{"title":"Clinical Impact and Safety Profile of Intravenous Lacosamide Administration as Adjunctive Therapy for Neonatal Seizures.","authors":"C Cortes-Ledesma, E Arias-Vivas, G Ruiz-Ocaña de Las Cuevas, E Santana-Cabrera, A Garcia-Ron","doi":"10.1177/08830738241296177","DOIUrl":"https://doi.org/10.1177/08830738241296177","url":null,"abstract":"The aim of this retrospective descriptive study was to evaluate the clinical impact and safety profile of lacosamide in neonates with symptomatic refractory seizures.Patients diagnosed with symptomatic refractory seizures who received lacosamide were included in the study. Follow-up assessments were conducted until 24 months of age, during which data on lacosamide dosage, duration of exposure, concurrent treatments, and potential side effects were collected. A total of eight patients were enrolled, with lacosamide administered as a third- or fourth-line treatment for symptomatic refractory seizures. Following loading dose, 62.5% of the patients achieved complete remission of seizure activity without recurrence. In the remaining cases, a reduction in seizure frequency was observed. No adverse effects attributable to lacosamide were reported.In conclusion, lacosamide may be effective in achieving seizure remission in newborns with symptomatic refractory seizures, and all patients demonstrate excellent tolerance. Brief exposure to lacosamide was sufficient, and no adverse effects were observed up to 24 months of age. However, randomized controlled trials are necessary to confirm these findings.","PeriodicalId":15319,"journal":{"name":"Journal of Child Neurology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Telemedicine in Pediatric Neurology: A Survey of Patient and Provider Experience. 儿科神经学远程医疗：患者和医疗服务提供者体验调查。

IF 2 4区医学

Journal of Child Neurology Pub Date : 2024-11-14 DOI: 10.1177/08830738241287243

Lauren Strasser, Lamia Hayawi, Richard J Webster, Sunita Venkateswaran, Katherine Muir

{"title":"Telemedicine in Pediatric Neurology: A Survey of Patient and Provider Experience.","authors":"Lauren Strasser, Lamia Hayawi, Richard J Webster, Sunita Venkateswaran, Katherine Muir","doi":"10.1177/08830738241287243","DOIUrl":"https://doi.org/10.1177/08830738241287243","url":null,"abstract":"Background: Over recent years there has been a shift in clinical practice to support care delivery via telemedicine. This study aims to highlight the patient and provider experience of telemedicine over 2.5 years within a Canadian Pediatric Neurology clinic.Method: A REDCap survey was sent to all patients/parents and providers with a telemedicine appointment between March 2020 and September 2022.Results: Seven providers and 272 patients responded. Ninety-one percent of patients and 100% of providers were satisfied with telemedicine. Ninety percent of patients and 100% of providers found telemedicine more convenient. Eighty-seven percent of patients and 100% of providers were interested in future telemedicine appointments. Main challenges were with performing a physical examination and technological issues.Conclusion: Our survey shows that the majority of patients and providers had highly positive experiences with telemedicine and were interested in continuing care via telemedicine. This study supports incorporating telemedicine into future pediatric neurology practice.","PeriodicalId":15319,"journal":{"name":"Journal of Child Neurology","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0