Journal of Brachial Plexus and Peripheral Nerve Injury最新文献

{"title":"A \"Common Sense\" Surgical Approach to Motor Shoulder Dysfunction Diagnosed as CRPS I/II Following Projectile Injuries to the Regio Deltoidea in the Late Stages of Ballistic Trauma.","authors":"Alexander A Gatskiy, Ihor B Tretyak, Vitaliy I Tsymbaliuk, Iurii L Chyrka, Sergii V Vernygorodskyi","doi":"10.1055/a-2858-9943","DOIUrl":"10.1055/a-2858-9943","url":null,"abstract":"<p><strong>Background: </strong>High-velocity projectile injuries to the regio deltoidea (RD) can result in persistent pain and motor shoulder dysfunction (MSD). The underlying mechanisms may involve direct axillary nerve (Ax) trauma or remote nociceptor irritation caused by cavitation effects.</p><p><strong>Objective: </strong>To characterize the anatomical basis of MSD and to establish a reliable diagnostic and surgical strategy for its management.</p><p><strong>Methods: </strong>Twenty-seven patients presenting with painful MSD following projectile trauma to the RD were included. Eight patients exhibited deltoid palsy associated with Ax injury, of whom three underwent Ax reconstruction. After positive diagnostic nerve blocks, 25 patients proceeded to denervation of the glenohumeral joint (GHJ): anterior ( <i>n</i>  = 15) or posterior ( <i>n</i>  = 3). Surgical procedures included neurotomy of the lateral pectoral nerve ( <i>n</i>  = 18), suprascapular nerve ( <i>n</i>  = 3), and Ax ( <i>n</i>  = 4). In patients with persistent CRPS-like symptoms, neurotomy of the intercostal nerves (ICN) was performed.</p><p><strong>Results: </strong>Pain relief following Ax surgery was achieved in 25%. Anterior GHJ denervation resulted in 60% pain improvement, whereas posterior showed no significant benefit. RD injuries in 45% cases exhibited CRPS type I-like manifestations. Subsequent ICN neurotomy in 12 patients effectively resolved these symptoms.</p><p><strong>Conclusion: </strong>High-velocity projectile injuries to the RD may provoke nociceptor irritation at a distance from the entry site through a cavitation mechanism. Direct Ax injury accounted for only 25% of MSD cases. Irritated nociceptors generate CRPS-like symptoms at painful MSD without overt nerve disruption. Targeted neurotomy of the involved nociceptors represents a reasonable therapeutic option for pain alleviation in selected patients.</p>","PeriodicalId":15280,"journal":{"name":"Journal of Brachial Plexus and Peripheral Nerve Injury","volume":"21 1","pages":"e13-e26"},"PeriodicalIF":1.1,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13138856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147838536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wrist Circumference-Dependent Thresholds for the Median Nerve in Carpal Tunnel Syndrome: A Cross-Cohort Comparison.","authors":"Tom B G Olde Dubbelink, Federica Ginanneschi, Paolo Falsetti, Jan Meulstee, Ronald H M A Bartels, Wim I M Verhagen","doi":"10.1055/a-2837-4022","DOIUrl":"10.1055/a-2837-4022","url":null,"abstract":"<p><strong>Background: </strong>Considerable between-center variability exists in the upper limit of normal (ULN) for the cross-sectional area (CSA) of the median nerve (MN) used to support the diagnosis of carpal tunnel syndrome (CTS).</p><p><strong>Objective: </strong>To evaluate whether a Dutch wrist circumference-dependent (WCD) equation for the ULN of MN CSA provides comparable classification of abnormal CSA in Italian and Dutch CTS populations.</p><p><strong>Methods: </strong>Wrist circumference (WC) and MN CSA were measured in 55 Italian (85 wrists) and 175 Dutch (175 wrists) patients with CTS. Abnormal wrists were identified using three thresholds: ULN9 (9 mm ² ), ULN11 (11 mm ² ), and a WCD equation ( <i>y</i>  = 0.88 * <i>x</i> - 4, with <i>y</i> as ULN in mm ² <i>x</i> as WC in cm). Findings were compared with electrodiagnostic results.</p><p><strong>Results: </strong>No significant differences in WC or MN CSA were observed between groups. The proportion of abnormal wrists in the Italian and Dutch populations, respectively, was 83.5 and 78.3% (ULN9, <i>p</i>  = 0.321), 49.4 and 50.3% (ULN11, <i>p</i>  = 0.895), and 61.1 and 55.4% (WCD, <i>p</i>  = 0.379). Among 12 Italian patients with small wrists, abnormal results were found in 75.0% (ULN9), 25.0% (ULN11), and 66.7% (WCD). All Italian patients had abnormal electrodiagnostic testing results, compared with 66.3% of Dutch patients ( <i>p</i>  < 0.0001).</p><p><strong>Conclusion: </strong>The WCD ULN for MN CSA yielded similar results in Italian and Dutch patients with CTS, and may be particularly useful in individuals with smaller wrists.</p>","PeriodicalId":15280,"journal":{"name":"Journal of Brachial Plexus and Peripheral Nerve Injury","volume":"21 1","pages":"e7-e12"},"PeriodicalIF":1.1,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13132619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147815621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nerve Transfer for Triceps Reinnervation in Obstetrical Brachial Plexus Injury: Long-Term Functional Results.","authors":"Filippo M Sénès, Francesca Susini, Maria Grazia Calevo, Chiara Arrigoni, Nunzio Catena","doi":"10.1055/a-2837-4190","DOIUrl":"10.1055/a-2837-4190","url":null,"abstract":"<p><strong>Background: </strong>Restoration of elbow extension in obstetric brachial plexus injury (OBPI) with triceps paralysis is essential for optimizing upper limb function, although often considered a secondary objective.</p><p><strong>Objective: </strong>To assess long-term functional outcomes of triceps reinnervation via nerve transfers in pediatric OBPI patients with persistent triceps paralysis.</p><p><strong>Methods: </strong>This retrospective cohort included 16 patients who underwent triceps reanimation between 2007 and 2018. Inclusion criteria were the absence of active elbow extension and a minimum 4-year follow-up. Depending on the lesion level, nerve transfers involved motor branches of the ulnar nerve to the flexor carpi ulnaris (FCUm) and intercostal nerves. Descriptive notes of these procedures are provided in the text. Outcomes were evaluated using the Medical Research Council (MRC) scale for strength and Gilbert's Elbow Scale (GES) for function.</p><p><strong>Results: </strong>Mean age at surgery was 48.9 months (range: 8-96), with a minimum follow-up of 4 years. At final evaluation, triceps strength improved significantly (mean MRC: 3.75, median: 4) as did elbow function (mean: GES 3.75, median: 4) compared with preoperative values ( <i>p</i>  < 0.01). Triceps recovery contributed to a mean 35-degree reduction in elbow flexion contracture, suggesting a preventive role against progressive deformity. No complications or donor site morbidity were observed.</p><p><strong>Conclusion: </strong>Delayed nerve transfers for triceps reinnervation-performed up to 8 years of age-yielded satisfactory long-term results without compromising recovery. These findings support including elbow extension restoration among surgical priorities in OBPI management, even for complete brachial plexus palsies when suitable donor nerves remain available after primary reconstructions.</p>","PeriodicalId":15280,"journal":{"name":"Journal of Brachial Plexus and Peripheral Nerve Injury","volume":"21 1","pages":"e1-e6"},"PeriodicalIF":1.1,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13065356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147673519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traumatic Upper Extremity Nerve Lesions in Children: High-Resolution Nerve Ultrasound Can Improve Surgical Outcome.","authors":"Natalie Winter, Alexander Grimm, Johannes Heinzel, Julia Wittlinger, Josua Kegele, Justus Lieber, Cristian Urla, Martin Ulrich Schuhmann, Helene Hurth","doi":"10.1055/a-2716-2279","DOIUrl":"10.1055/a-2716-2279","url":null,"abstract":"<p><strong>Background: </strong>Peripheral nerve injuries may accompany traumatic extremity injuries and are associated with significant morbidity. Diagnostic options are limited in young children since compliance might be restricted. High-resolution ultrasound (HRUS) is a promising technique to close the diagnostic gap, but clear recommendations are lacking. This study evaluates clinical outcomes after conservative versus surgical management, considering HRUS findings in pediatric patients with upper extremity peripheral nerve injuries.</p><p><strong>Methods: </strong>We retrospectively analyzed our pediatric neurosurgery database from August 2008 to December 2022 including patients < 18 years with traumatic upper extremity nerve injury and excluding obstetrical brachial plexus injury. Systematic HRUS examinations were implemented from 2016 onwards. Clinical, intraoperative, sonographic and electrophysiological findings were assessed.</p><p><strong>Results: </strong>A total of 73 nerve injuries in 67 patients (median age = 7.0 years) were analyzed. The most frequently affected nerves were the ulnar (49.3%), radial (21.9%), and median nerve (19.2%). At initial presentation, 47.9% underwent electrophysiology and 67.1% received HRUS. Surgery was performed in 49.3% at a median of 4 months posttrauma, whereas 50.7% were managed conservatively. Patients undergoing surgery initially had more severe sensory and motor deficits (χ ²  = 3.98, <i>p</i>  = 0.046), but final outcomes showed no significant difference in nerve function (median follow-up = 6.0 months). Binary logistic regression identified age (odds ratio [OR] = 1.3, <i>p</i>  = 0.028), HRUS (OR = 10.6, <i>p</i>  = 0.035), and injured nerve (OR = 3.1, <i>p</i>  = 0.022) as independent outcome predictors.</p><p><strong>Interpretation: </strong>Good functional recovery in pediatric patients with peripheral nerve injury was demonstrated. HRUS-guided treatment and age < 9 years were independent predictors of favorable outcome. These findings support HRUS as a valuable, noninvasive tool for guiding pediatric nerve injury management.</p>","PeriodicalId":15280,"journal":{"name":"Journal of Brachial Plexus and Peripheral Nerve Injury","volume":"20 1","pages":"e87-e95"},"PeriodicalIF":1.0,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12552066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145372788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Bibliometric Analysis of the Top 50 Most Cited Articles on Iatrogenic Nerve Injuries of the Upper Limb Following Surgery.","authors":"Saran Singh Gill, Abith Ganesh Kamath, Hussayn Shinwari, Ashley Simpson, Anna Panagiotidou, Mike Fox, Marco Sinsi, Kapil Sugand","doi":"10.1055/a-2702-5186","DOIUrl":"10.1055/a-2702-5186","url":null,"abstract":"<p><strong>Background: </strong>Iatrogenic nerve injuries of the upper limb have profound impacts on patients their pain, functionality, and quality of life.</p><p><strong>Objectives: </strong>This study aims to identify and analyze the most cited publications on those iatrogenic injuries to elicit trends, thematic analysis, and reduce risk.</p><p><strong>Methodology: </strong>A bibliometric analysis was performed using the Web of Science database. Search terms included \"Iatrogenic,\" \"Upper Limb,\" \"Nerve,\" and \"Injury.\" The top 50 cited peer-reviewed publications were ranked by citation count and analyzed for publication year, journal, country of origin, institutional affiliations, authorship, and research focus. Trends in diagnostic and management practices were also evaluated.</p><p><strong>Results: </strong>The most cited articles, published between 1995 and 2022, peaked in publication frequency in 2010 and 2017 ( <i>n</i>  = 4 each). Citation counts ranged from 7 to 260, with a median of 26.5 (± 15.0, 95% confidence interval: 16-75). These articles were featured in 44 journals. The United States emerged as the leading contributor in both volume and impact ( <i>n</i>  = 16). Prominent themes included supracondylar humerus fractures ( <i>n</i>  = 21) and humeral shaft fractures ( <i>n</i>  = 10), alongside mentions of diaphyseal humeral fractures and shoulder surgery ( <i>n</i>  = 4 each). Ulnar nerve injuries were the most frequently discussed ( <i>n</i>  = 23), followed by injuries involving multiple nerves ( <i>n</i>  = 18) and the radial nerve ( <i>n</i>  = 14).</p><p><strong>Conclusions: </strong>This bibliometric analysis highlights key studies on iatrogenic upper limb nerve injuries, identifies trends and gaps, and lays a foundation for evidence-based protocols. It also serves as a guide for future research and collaborative efforts to improve prevention and treatment.</p>","PeriodicalId":15280,"journal":{"name":"Journal of Brachial Plexus and Peripheral Nerve Injury","volume":"20 1","pages":"e71-e82"},"PeriodicalIF":1.0,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12503984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145251170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fascicular Injury in True Neurogenic Thoracic Outlet Syndrome Associated with Manual and Shockwave Therapies: A Case Report.","authors":"Jae Jun Nam, Yeongyoon Koh, Jong Woong Park, In Cheul Choi","doi":"10.1055/a-2700-4984","DOIUrl":"10.1055/a-2700-4984","url":null,"abstract":"<p><p>True neurogenic thoracic outlet syndrome (nTOS) is a rare condition resulting from brachial plexus compression, frequently associated with congenital anomalies such as cervical ribs or fibrous bands. We report a unique case of nTOS involving both a cervical rib and fibrous band, complicated by an incidental intraoperative finding of a fascicular rupture in the lower part of lower trunk. Notably, the patient had no history of trauma but had undergone multiple sessions of manual therapy and a single extracorporeal shockwave therapy to the cervical region, raising concerns about a potential iatrogenic contribution.</p>","PeriodicalId":15280,"journal":{"name":"Journal of Brachial Plexus and Peripheral Nerve Injury","volume":"20 1","pages":"e83-e86"},"PeriodicalIF":1.0,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12503974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145251114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of a Pedicled Vascularized Ulnar Nerve as a Long Graft for Complete Brachial Plexus Palsy in Adults to Restore Elbow Flexion: Should this Practice Continue?","authors":"Camille Echalier, Jean Noël Goubier","doi":"10.1055/a-2694-8871","DOIUrl":"10.1055/a-2694-8871","url":null,"abstract":"<p><p>Restoring elbow flexion is a priority in adults with complete brachial plexus palsy. If the nerve root is not avulsed, a graft can be placed between the existing root and the musculocutaneous nerve. The aim of this study was to evaluate the outcomes of using vascularized ulnar nerve grafts in this context. Our case series consisted of 17 male and 3 female patients (mean age of 31 years) presenting complete brachial plexus palsy after a motorcycle accident. A graft at the C5 or C6 root on the musculocutaneous nerve was done in all patients using a pedicled vascularized ulnar nerve to restore elbow flexion at a mean of 5 months after the accident. At a mean follow-up of more than 3 years, elbow flexion was graded as M4 in six patients and between M0 and M2 in the other 14 patients on the Medical Research Council scale. None of the patients had M3 strength. While the results of long grafts using a vascularized ulnar nerve are disappointing in this case series, they are consistent with previous publications. Encouraging results have only been reported with short grafts (<10 cm), which can rarely be used with supraclavicular lesions. For this reason, we currently prefer using a sural nerve graft or nerve transfer, when possible, to restore elbow flexion in adult patients with brachial plexus injuries.</p>","PeriodicalId":15280,"journal":{"name":"Journal of Brachial Plexus and Peripheral Nerve Injury","volume":"20 1","pages":"e66-e70"},"PeriodicalIF":1.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12453903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fracture Patterns and Peripheral Brachial Plexus Injury in Humerus Fractures: A Retrospective Study.","authors":"Mohammed Musaed Almalki, Bander S Alrashedan, Ahmed Shaya Alragea, Adel Faiz Alshihri, Hani S Serhan, Husam Fahmi AlFashtaki","doi":"10.1055/a-2596-1347","DOIUrl":"10.1055/a-2596-1347","url":null,"abstract":"<p><strong>Background: </strong>Peripheral brachial plexus injuries, particularly Radial nerve palsy (RNP), are a common complication of humeral shaft fractures. Despite previous research, the specific fracture patterns associated with RNP remain unclear.</p><p><strong>Objectives: </strong>This study aims to assess the frequency and patterns of humeral shaft fractures, determine the incidence of peripheral brachial plexus injuries such as radial and ulnar nerve palsies, and investigate the association between specific fracture patterns and these nerve injuries. We also explored other factors influencing RNP development and identified potential risk factors or predictors.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed 144 patients with humeral shaft fractures at King Saud Medical City from 2015 to 2022. Patient data, such as age, gender, and neurovascular status, were extracted and analyzed using SPSS. RNP was diagnosed clinically. Statistical analyses included chi-square and student <i>t</i> -tests, with a <i>p</i> -value of <0.05 for significance.</p><p><strong>Results: </strong>This study found a 37.5% incidence of RNP in humeral shaft fractures. Significant differences were observed in age ( <i>p</i>  = 0.032) and mechanism of injury ( <i>p</i>  < 0.0001), with most fractures due to road traffic accidents (72.22%) and closed (93.75%). Common fracture patterns were AO 12A (37.5%) and AO 12B (39.58%), with a higher prevalence of comminuted fractures (71 cases). Significant differences in fracture patterns ( <i>p</i>  < 0.0001) and anteromedial comminution ( <i>p</i>  = 0.002) were noted between patients with and without RNP. Interestingly, four cases of concomitant ulnar nerve palsy were observed in patients with radial nerve palsy. However, no significant differences were found in gender ( <i>p</i>  = 0.343), open fractures ( <i>p</i>  = 0.214), or associated fractures ( <i>p</i>  = 0.106).</p><p><strong>Conclusion: </strong>This study suggests that the severity of trauma, rather than specific fracture patterns, is a more significant factor in RNP development in humeral shaft fractures. Further research is needed to understand the underlying biomechanics.</p>","PeriodicalId":15280,"journal":{"name":"Journal of Brachial Plexus and Peripheral Nerve Injury","volume":"20 1","pages":"e53-e58"},"PeriodicalIF":1.0,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144955526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ulnar Nerve Granuloma Presenting as a Peripheral Nerve Sheath Tumor: A Case Report and Literature Review.","authors":"John K Yue, Jia-Shu Chen, Mahmoud M Elguindy, Vivian Tang, Ryan Tripathy, Allison R Bond, Alexander A Aabedi, Vinil N Shah, Arie Perry, Andrew W Bollen, Dong Heun Lee, Line G Jacques","doi":"10.1055/a-2667-7286","DOIUrl":"10.1055/a-2667-7286","url":null,"abstract":"<p><p>Peripheral nerve masses have a wide differential diagnosis; however, there is no established diagnostic framework for evaluating non-neoplastic etiologies, such as inflammatory or infectious lesions. Here, we present a rare case of an ulnar nerve granuloma that initially mimicked a peripheral nerve sheath tumor (PNST) on imaging and clinical presentation to elucidate the relevant medical history, imaging, and histology that aid in distinguishing inflammatory, infectious, and neoplastic peripheral nerve lesions. An 85-year-old man with melanoma and multiple prior right elbow surgeries presented with right-hand weakness and a rapidly enlarging gadolinium-enhancing ulnar nerve mass suggestive of a PNST that warranted surgical resection. Surgical histology showed a necrotizing granulomatous lesion that then became most concerning for a parasitic infection. However, broad serum and histologic testing by the Centers for Disease Control and Prevention were all ultimately negative. The final diagnosis was an inflammatory reaction to a retained foreign body from his prior elbow surgeries. In summary, surgery and comprehensive histologic workup are required for diagnosing granulomatous peripheral nerve lesions that mimic PNSTs on imaging and infection on histology.</p>","PeriodicalId":15280,"journal":{"name":"Journal of Brachial Plexus and Peripheral Nerve Injury","volume":"20 1","pages":"e59-e65"},"PeriodicalIF":1.0,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144955570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple Electrophysiological Evaluation of Carpal Tunnel Syndrome.","authors":"XueYan Wu, Qiuju Su, Ping Ding, Jie Ji, JiaYi Zhu","doi":"10.1055/a-2644-7508","DOIUrl":"10.1055/a-2644-7508","url":null,"abstract":"<p><strong>Introduction: </strong>To investigate a high-sensitivity electrodiagnostic (EDX) combination for diagnosing mild carpal tunnel syndrome (CTS).</p><p><strong>Methods: </strong>A total of 68 healthy controls (HCs, 136 hands) and 91 adult patients (CTSs, 162 hands) clinically diagnosed with CTS were enrolled. All patients accepted EDXs, including the sensory ganglia segment method of the median and ulnar nerves, and motor nerve conduction of the median and ulnar nerves. We examined the electrophysiological results and compared the sensitivity and specificity of various sensory nerve detection methods for the median nerve between the two groups.</p><p><strong>Results: </strong>The electrophysiological results of the CTSs were significantly different from those of HCs. All EDX techniques selected showed high specificity (>96.3%), positive predictive value (>95.2%), and large area under the curve (0.922 as the smallest) for the diagnosis of CTSs. A comparison of the median distal sensory latencies with the ulnar distal sensory latencies in fingers 2 and 4 showed a high sensitivity of 98.1%. Comparison of the nerve conduction study between the median and ulnar nerves in the same hand is the most reliable EDX technique for diagnosing very mild CTS because of its high sensitivity and specificity.</p><p><strong>Conclusion: </strong>If clinical CTS patients exhibit normal median motor distal latency or sensory nerve conduction velocity across the wrist, a comparison of median and ulnar nerve conduction through the wrist, including M-U and M-U ringdiff, is recommended.</p>","PeriodicalId":15280,"journal":{"name":"Journal of Brachial Plexus and Peripheral Nerve Injury","volume":"20 1","pages":"e47-e52"},"PeriodicalIF":1.1,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12283220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144698669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}