Soyoon Park, Woo-Baek Chung, Joo Hyun O, Kwan Yong Lee, Mi-Hyang Jung, Hae-Ok Jung, Kiyuk Chang, Ho-Joong Youn
{"title":"Trans-Aortic Flow Turbulence and Aortic Valve Inflammation: A Pilot Study Using Blood Speckle Imaging and <sup>18</sup>F-Sodium Fluoride Positron Emission Tomography/Computed Tomography in Patients With Moderate Aortic Stenosis.","authors":"Soyoon Park, Woo-Baek Chung, Joo Hyun O, Kwan Yong Lee, Mi-Hyang Jung, Hae-Ok Jung, Kiyuk Chang, Ho-Joong Youn","doi":"10.4250/jcvi.2022.0118","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0118","url":null,"abstract":"<p><strong>Background: </strong><sup>18</sup>F-sodium fluoride positron emission tomography/computed tomography (<sup>18</sup>F-NaF PET/CT) has been proven to be useful in identification of microcalcifications, which are stimulated by inflammation. Blood speckle imaging (BSI) is a new imaging technology used for tracking the flow of blood cells using transesophageal echocardiography (TEE). We evaluated the relationship between turbulent flow identified by BSI and inflammatory activity of the aortic valve (AV) as indicated by the <sup>18</sup>F-NaF uptake index in moderate aortic stenosis (AS) patients.</p><p><strong>Methods: </strong>This study enrolled 18 moderate AS patients diagnosed within the past 6 months. BSI within the aortic root was acquired using long-axis view TEE. The duration of laminar flow and the turbulent flow area ratio were calculated by BSI to demonstrate the degree of turbulence. The maximum and mean standardized uptake values (SUVmax, SUVmean) and the total microcalcification burden (TMB) as measured by <sup>18</sup>F-NaF PET/CT were used to demonstrate the degree of inflammatory activity in the AV region.</p><p><strong>Results: </strong>The mean SUVmean, SUVmax, and TMB were 1.90 ± 0.79, 2.60 ± 0.98, and 4.20 ± 2.18 mL, respectively. The mean laminar flow period and the turbulent area ratio were 116.1 ± 61.5 msec and 0.48 ± 0.32. The correlation between SUVmax and turbulent flow area ratio showed the most positive and statistically significant correlation, with a Pearson's correlation coefficient (R²) of 0.658 and a p-value of 0.014.</p><p><strong>Conclusions: </strong>The high degree of trans-aortic turbulence measured by BSI was correlated with severe AV inflammation.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 3","pages":"145-149"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3b/96/jcvi-31-145.PMC10374388.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9888890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana Ribeiro Silva, Nuno Dias Ferreira, Daniel Martins, Alberto Rodrigues, Ricardo Fontes-Carvalho
{"title":"\"UFO: Unidentified Flying Object in the Heart\": An Unusual Sighting of a Cardiac Calcified Amorphous Tumour.","authors":"Mariana Ribeiro Silva, Nuno Dias Ferreira, Daniel Martins, Alberto Rodrigues, Ricardo Fontes-Carvalho","doi":"10.4250/jcvi.2022.0139","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0139","url":null,"abstract":"","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 3","pages":"155-157"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/db/17/jcvi-31-155.PMC10374386.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9888889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Path to Accurate and Universal Strain Measurement: Insights From a Validation Study.","authors":"Goo-Yeong Cho","doi":"10.4250/jcvi.2023.0029","DOIUrl":"https://doi.org/10.4250/jcvi.2023.0029","url":null,"abstract":"https://e-jcvi.org While myocardial strain measurement is not currently considered a mandatory assessment in the guidelines of various cardiac disease, unlike left ventricular ejection fraction, it is a topic of active research among many investigators due to its potential clinical utility.1) The results of these studies have been promising, suggesting that myocardial strain measurement could become a necessary assessment in the near future. However, there are several challenges that need to be addressed before myocardial strain can be widely used in routine clinical practice. One of the main issues is that strain values can vary depending on the software used for measurement, and there is currently no standardization method for correcting these differences. As a result, it can be difficult to compare strain values obtained using different software programs, which can limit the utility of strain measurements in clinical decision-making. As such, the validation of strain measurement software is a critical step in establishing the reliability and accuracy of this tool. As these developments continue, it is likely that myocardial strain measurement will become an increasingly important tool for the diagnosis, treatment, and management of cardiac disease.","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 3","pages":"142-144"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4f/95/jcvi-31-142.PMC10374385.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9888885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luuk H G A Hopman, Elizabeth Hillier, Yuchi Liu, Jesse Hamilton, Kady Fischer, Nicole Seiberlich, Matthias G Friedrich
{"title":"Dynamic Cardiac Magnetic Resonance Fingerprinting During Vasoactive Breathing Maneuvers: First Results.","authors":"Luuk H G A Hopman, Elizabeth Hillier, Yuchi Liu, Jesse Hamilton, Kady Fischer, Nicole Seiberlich, Matthias G Friedrich","doi":"10.4250/jcvi.2022.0080","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0080","url":null,"abstract":"BACKGROUND Cardiac magnetic resonance fingerprinting (cMRF) enables simultaneous mapping of myocardial T1 and T2 with very short acquisition times. Breathing maneuvers have been utilized as a vasoactive stress test to dynamically characterize myocardial tissue in vivo. We tested the feasibility of sequential, rapid cMRF acquisitions during breathing maneuvers to quantify myocardial T1 and T2 changes. METHODS We measured T1 and T2 values using conventional T1 and T2-mapping techniques (modified look locker inversion [MOLLI] and T2-prepared balanced-steady state free precession), and a 15 heartbeat (15-hb) and rapid 5-hb cMRF sequence in a phantom and in 9 healthy volunteers. The cMRF5-hb sequence was also used to dynamically assess T1 and T2 changes over the course of a vasoactive combined breathing maneuver. RESULTS In healthy volunteers, the mean myocardial T1 of the different mapping methodologies were: MOLLI 1,224 ± 81 ms, cMRF15-hb 1,359 ± 97 ms, and cMRF5-hb 1,357 ± 76 ms. The mean myocardial T2 measured with the conventional mapping technique was 41.7 ± 6.7 ms, while for cMRF15-hb 29.6 ± 5.8 ms and cMRF5-hb 30.5 ± 5.8 ms. T2 was reduced with vasoconstriction (post-hyperventilation compared to a baseline resting state) (30.15 ± 1.53 ms vs. 27.99 ± 2.07 ms, p = 0.02), while T1 did not change with hyperventilation. During the vasodilatory breath-hold, no significant change of myocardial T1 and T2 was observed. CONCLUSIONS cMRF5-hb enables simultaneous mapping of myocardial T1 and T2, and may be used to track dynamic changes of myocardial T1 and T2 during vasoactive combined breathing maneuvers.","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 2","pages":"71-82"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/43/13/jcvi-31-71.PMC10133810.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9395787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Longitudinal Changes of Left Atrial Volume Index as a Prognosticator in Hypertrophic Cardiomyopathy.","authors":"Sungseek Kim, Wook-Jin Chung","doi":"10.4250/jcvi.2022.0143","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0143","url":null,"abstract":"outflow tract obstruction, LAVI, E/e ′ , tricuspid regurgitation velocity","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 2","pages":"96-97"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7a/76/jcvi-31-96.PMC10133809.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9395790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is a Low Dose Computed Tomography Angiography Protocol Feasible in Terms of Maintaining Adequate Diagnostic Image Quality for TAVR Candidates?","authors":"Sung Min Ko","doi":"10.4250/jcvi.2023.0022","DOIUrl":"https://doi.org/10.4250/jcvi.2023.0022","url":null,"abstract":"https://e-jcvi.org Transcatheter aortic valve replacement (TAVR) has been initiated first for inoperable patients with severe aortic stenosis (AS) and prohibitive comorbidities, then in high-, intermediateand, more recently, low-risk patients. Nowadays, TAVR has been established as the firstline treatment method for symptomatic patients of any age with severe AS and a high or prohibitive surgical risk.1) Computed tomography angiography (CTA) allows pre-procedural comprehensive evaluation for TAVR including coronary artery, aortic valve, aortic root, entire aorta, and vascular access site suitability at the same time.2) Accordingly, large amount of contrast medium is mandatory for obtaining good quality of images from the subclavian arteries to the femoral arteries. Chronic kidney disease is a common underlying disease in patients with severe AS and is significantly associated with aggravation of renal function in case of excessive use of iodinated contrast medium during both the pre-TAVR planning and TAVR procedure.3)4) Therefore, reducing the use of contrast medium for pre-procedural CTA imaging in TAVR is required for prevention of deteriorating renal function and worsening clinical outcomes in patients with renal dysfunction.","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 2","pages":"116-117"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0c/b7/jcvi-31-116.PMC10133808.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9390404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Strain Measurement for Assessment of Treatment Response: One Step Closer to Routine Clinical Practice.","authors":"In-Chang Hwang","doi":"10.4250/jcvi.2023.0001","DOIUrl":"https://doi.org/10.4250/jcvi.2023.0001","url":null,"abstract":". The post-KT improvements in LV-GLS shown in the present study should be interpreted in the context of a recently published study in JACC Cardiovascular Imaging by the same group, which expands the clinical implications of the present JCVI study.","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 2","pages":"105-107"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/b9/jcvi-31-105.PMC10133813.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9395788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ga Yun Kim, Sang Hyun Lee, Seok Hyun Kim, Jeongsu Kim, Yong Hyun Park
{"title":"Temporary Arteriovenous Fistula Compression for Clinical Decision-Making in Patients on Hemodialysis With Significant Aortic Stenosis.","authors":"Ga Yun Kim, Sang Hyun Lee, Seok Hyun Kim, Jeongsu Kim, Yong Hyun Park","doi":"10.4250/jcvi.2022.0088","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0088","url":null,"abstract":"https://e-jcvi.org A 57-year-old woman complained of dyspnea of New York Heart Association (NYHA) class III–IV and was transferred for surgery for severe degenerative aortic stenosis (AS). She had past history of chronic kidney disease on hemodialysis and hypertension. Initial echocardiography revealed moderate to severe degenerative AS with severe resting pulmonary hypertension (PH) and preserved left ventricular ejection fraction. Right heart catheterization was performed to find the cause of PH. The results showed combined post-capillary and pre-capillary PH with elevated cardiac index (CI) to 4.28 L/min/m2 (Table 1). Considering these results, the patient underwent intensive hemodialysis to reduce intravascular volume. However, AS peak jet velocity (Vpeak) was still high of 4.7 m/s with severe resting PH after volume reduction (Figure 1A). While evaluating causes of elevated CI, we found arteriovenous fistula (AVF) with high access flow rate (Figure 2). To determine the effects of increased transvalvular flow on measured parameters, we temporarily compressed AVF with blood pressure cuff to reduce shunt flow during echocardiography. During compression, Vpeak of aortic valve decreased to 3.6 m/s (Movies 1 and 2). The patient had revision of AVF to reduce shunt flow. After revision, echocardiography revealed moderate AS (Vpeak: 3.4 m/s) with mild resting PH (Figure 1B) and dyspnea was improved to NYHA class II. Continuity equation valve area was the same before and after surgery with value of 1.1 cm2 (Figure 3). High-flow state can overestimate AS severity.1) Causes of high-flow state should be identified and severity should be re-assessed when normal flow is restored.2) Temporary compression of AVF may be used for this purpose.1) J Cardiovasc Imaging. 2023 Apr;31(2):118-120 https://doi.org/10.4250/jcvi.2022.0088 pISSN 2586-7210·eISSN 2586-7296","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 2","pages":"118-120"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5f/4c/jcvi-31-118.PMC10133805.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9390405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Spencer C Lacy, Mina M Benjamin, Mohammed Osman, Mushabbar A Syed, Menhel Kinno
{"title":"Low Contrast and Low kV CTA Before Transcatheter Aortic Valve Replacement: A Systematic Review.","authors":"Spencer C Lacy, Mina M Benjamin, Mohammed Osman, Mushabbar A Syed, Menhel Kinno","doi":"10.4250/jcvi.2022.0108","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0108","url":null,"abstract":"<p><strong>Background: </strong>Minimizing contrast dose and radiation exposure while maintaining image quality during computed tomography angiography (CTA) for transcatheter aortic valve replacement (TAVR) is desirable, but not well established. This systematic review compares image quality for low contrast and low kV CTA versus conventional CTA in patients with aortic stenosis undergoing TAVR planning.</p><p><strong>Methods: </strong>We performed a systematic literature review to identify clinical studies comparing imaging strategies for patients with aortic stenosis undergoing TAVR planning. The primary outcomes of image quality as assessed by the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were reported as random effects mean difference with 95% confidence interval (CI).</p><p><strong>Results: </strong>We included 6 studies reporting on 353 patients. There was no difference in cardiac SNR (mean difference, -1.42; 95% CI, -5.71 to 2.88; p = 0.52), cardiac CNR (mean difference, -3.83; 95% CI, -9.98 to 2.32; p = 0.22), aortic SNR (mean difference, -0.23; 95% CI, -7.83 to 7.37; p = 0.95), aortic CNR (mean difference, -3.95; 95% CI, -12.03 to 4.13; p = 0.34), and ileofemoral SNR (mean difference, -6.09; 95% CI, -13.80 to 1.62; p = 0.12) between the low dose and conventional protocols. There was a difference in ileofemoral CNR between the low dose and conventional protocols with a mean difference of -9.26 (95% CI, -15.06 to -3.46; p = 0.002). Overall, subjective image quality was similar between the 2 protocols.</p><p><strong>Conclusions: </strong>This systematic review suggests that low contrast and low kV CTA for TAVR planning provides similar image quality to conventional CTA.</p>","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 2","pages":"108-115"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fe/ec/jcvi-31-108.PMC10133812.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9390402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aortic Root Honeycomb: A Rare Cardiac Surgery Complication.","authors":"Joana Laranjeira Correia, Vanda Devesa Neto, Gonçalo Rm Ferreira, Davide Moreira, Rogério Teixeira","doi":"10.4250/jcvi.2022.0100","DOIUrl":"https://doi.org/10.4250/jcvi.2022.0100","url":null,"abstract":"https://e-jcvi.org A 33-year-old male was being followed in the cardiology outpatient clinic, after a tricuspid aortic valve replacement with a double-disc mechanical valve due to rheumatic aortic valve disease (Movies 1 and 2). The postoperative period was complicated by mediastinitis and Saphylococcus aureus bacteremia (without evidence of endocarditis), which resolved after a four-week course of targeted antibiotic therapy. The patient had no other relevant past medical conditions and was medicated with warfarin. No other clinically relevant events were reported since the valvular surgery and an echocardiography performed one year after the surgery revealed a normally functioning aortic prosthesis.","PeriodicalId":15229,"journal":{"name":"Journal of Cardiovascular Imaging","volume":"31 2","pages":"121-123"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/14/88/jcvi-31-121.PMC10133814.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9390403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}