Journal of Berry Research最新文献

{"title":"Hybrid RSM-GA approach to optimize extraction conditions for blueberry anthocyanins with high antioxidant activity","authors":"X. Fang, Weijie Wu, Honglei Mu, Hangjun Chen, Xiaolin Zheng, Haiyan Gao","doi":"10.3233/jbr-230016","DOIUrl":"https://doi.org/10.3233/jbr-230016","url":null,"abstract":"BACKGROUND: Blueberry contains an abundance of anthocyanins, which are a bioactive component of this fruit. Anthocyanins can be extracted via various methods, and each has pros and cons. OBJECTIVE: This current study reported the optimal conditions for the ultrasonic-assisted enzymatic extraction of blueberry anthocyanins simulated using response surface methodology (RSM) coupled with a genetic algorithm (GA). METHODS: The Box–Behnken design (BBD) was used for the RSM, and the extraction conditions were as follows: temperature, 42°C; ultrasonic power, 310 W; enzyme volume, 0.25% ; and extraction time, 42 min. RESULTS: The maximum predicted extraction yield was 6.67 mg/g. The antioxidant activity of anthocyanins extracted via RSM and GA was based on the hydroxyl free radical activity and supersonic anion free radical activity of 230.50±12.76μg/ml and 4.41±0.36μg/ml, respectively. Anthocyanins exracted by the proposed method has stronger free radical removal capacity than that of Vc. CONCLUSIONS: This study shows that the combination of RSM with GA represents an optimized method for extracting blueberry anthocyanins for use in the food industry. This method can maintain high antioxidant potential and can be used as an alternative strategy for high-value products.","PeriodicalId":15194,"journal":{"name":"Journal of Berry Research","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46178396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive evaluation of nine grape varieties based on fundamental physical and chemical indicators, color and volatile compounds","authors":"W. Cao, Nan Shu, Yiming Yang, Jinli Wen, Wenpeng Lu","doi":"10.3233/jbr-220080","DOIUrl":"https://doi.org/10.3233/jbr-220080","url":null,"abstract":"BACKGROUND: In todays’ society, the rapid development of the wine industry and the improvement of peoples’ living standards make people pay more and more attention to wine grape quality. OBJECTIVE: To evaluate the wine grape varieties in Northeast Chinas’ grape growing regions for better wine grape quality, we evaluated the quality of different varieties of wine grapes. METHODS: The grape varieties ‘Hassan’ ‘Zuoshaner’ ‘Beibinghong’ ‘Zuoyouhong’ ‘Beta’ ‘Shuanghong’ ‘Zijingganlu’ ‘Cabernet Sauvignon’ and ‘Syrah’ were planted in the grape growing area of Jilin, Northeast China, were used as the subjects of this study. The grape berries were analyzed and tested for morphological indicators, basic physicochemical indicators, color, and phenolic and aromatic composition. RESULTS: According to lab results, ‘Hassan’ contained the highest amount of total phenolics; ‘Zuoyouhong’ had the highest solids and total sugar content; ‘Shuanghong’ had the most elevated total acid and anthocyanin content; ‘Zijngganlu’ had the highest tannin content and acid fixation ratio; Seventy-one volatile compounds were detected in nine grape varieties. CONCLUSIONS: Each of the nine grape varieties has a distinctive flavor, and because of this, grape processing products with regional flavors can be created. The same offer valuable data for future scientific grape resource collection, conservation, and exploitation.","PeriodicalId":15194,"journal":{"name":"Journal of Berry Research","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47879399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization of microwave assisted extraction and biological activities of total flavonoids from grape seed using response surface methodology","authors":"Yao Wen, Caimei Su, Xueying Mai","doi":"10.3233/jbr-220081","DOIUrl":"https://doi.org/10.3233/jbr-220081","url":null,"abstract":"Aiming to reduce the environmental contamination and resource wastage generated by discarded grape seed, the management of discarded grape seed should be carried out and their potential bioactivities and pharmacological properties ought to be exploited to the fullest extent possible. A Box–Behnken design of response surface methodology was employed to further optimize microwave-assisted extraction setting for grape seed total flavonoids (GSFE). In addition, the extract (GSFE) of total flavonoids obtained were refined through AB-8 macroporous resin for obtaining more pure flavonoid (GSFP) with determination of their in vitro hypoglycemic activity and antioxidant activity. The results indicated that following optimized extraction conditions were achieved: ethanol concentration 50% liquid-solid ratio 21:1 mL/g, microwave power 540 W, microwave time 126 s. Below mentioned conditions, the extraction yield reached an average experimental value (1.979 mg/g), representing 1.69 times higher than that of water extraction (1.17 mg/g). In contrast to GSFE, the purity of GSFE after purification (GSFP) exhibited a high degree of purity at 13.753 mg/g, representing nearly 2.50 times that of GSFE (3.926 mg/g). GSFP possessed high α-glucosidase and α-amylase inhibitory activities as well as DPPH and ABTS + free radical scavenging activities with an IC50 value of 0.00641, 0.0257, 0.0669 and 0.0708 mg/mL, inferior to that of GSFE (0.0514, 0.186, 0.129 and 0.223 mg/g). Within present work, the microwave technique for extraction of total flavonoids from grape seeds was investigated with an efficient and cost-effective extraction method. Total flavonoids of grape seeds have certain in vitro blood glucose and antioxidant activity, and the purified total flavonoid biological activity has improved, laying the foundation for further study of its pharmacological activity.","PeriodicalId":15194,"journal":{"name":"Journal of Berry Research","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42095563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of yield, biochemical characteristics and nutrient composition of ‘Camarosa’ strawberry in response to different K/N ratios","authors":"S. Yousefi, S. Eshghi, B. Jamali","doi":"10.3233/jbr-220056","DOIUrl":"https://doi.org/10.3233/jbr-220056","url":null,"abstract":"BACKGROUND: The normal growth and yield of strawberry plant are affected by lack of balanced fertilization. OBJECTIVE: This study was carried out to evaluate the effects of different N/K ratios of nutrient solution on yield, some biochemical characteristics, macro-, and micronutrient concentrations, absorption, and translocation factor in strawberry ‘Camarosa’. METHODS: Three concentration levels of K (200, 250, and 300 mg l–1, using KNO3, KCl, and K2SO4) and two concentration levels of N (120 and 180 mg l–1, using NH4H2PO4, Ca(NO3)2, and KNO3) were applied during two vegetative and reproductive growth stages. RESULTS: The results showed that the highest productivity (149.05 g/plant), soluble sugars, and starch content were obtained from plants which had received a K/N ratio of 200/180 and 300/120 mg l–1 during the vegetative and reproductive stages, respectively. Plants treated with the highest K and N concentrations (300 and 180 mg l–1, respectively) during the vegetative and reproductive stages had the highest leaf area, photochemical efficiency of photosystem II (Fv/Fm), as well as shoot and root dry weight. High N and low K concentration in the nutrient solution increased concentrations of N, Ca, Mg, Mn, and Zn while decreased K and Fe concentrations. In addition, higher N levels increased the uptake of N, P, K, Ca, Mg, Mn, and Zn. At a K/N ratio of 200/120 mg l–1, the translocation factor of N decreased, while the translocation factor of K and Mg increased. CONCLUSION: In conclusion, the changes in the K/N ratio significantly affected the concentration of nutrient elements, absorption and translocation factor.","PeriodicalId":15194,"journal":{"name":"Journal of Berry Research","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49209603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using the experimental model C. elegans to in vivo deepen into the biomedical properties of the Romina strawberry (Fragaria x ananassa) cultivar: A look into tau protein-related Alzheimer’s disease, aging and redox biology","authors":"M. Navarro-Hortal, T. Forbes-Hernández, Jose M. Romero-Márquez, Yasmany Armas-Díaz, Alina E. Pascual-Barrera, F. Giampieri, L. Rivas-García, C. Sánchez-González, M. Battino, J. Quiles","doi":"10.3233/jbr-230009","DOIUrl":"https://doi.org/10.3233/jbr-230009","url":null,"abstract":"BACKGROUND: Romina strawberry cultivar is rich in bioactive compounds. Healthy properties of Romina have been only partially investigated. There are almost no information concerning aging and age-related diseases like Alzheimer’s Disease (AD). OBJECTIVE: To evaluate about the effects of a methanolic extract of the strawberry Romina cultivar on aging, redox biology, and tau protein-related aspects of AD in Caenorhabditis elegans. METHODS: Caenorhabditis elegans strains were treated with 100, 500 or 1000μg/mL of a methanolic extract of the Romina cultivar and evaluated for toxicity, lifespan, tau protein expression and redox biology markers. RESULTS: No toxicity was found. Tau expression was lower in nematodes treated with 500 and 1000μg/mL. All treatments induced higher lifespan than control. Lipofuscin expression was higher in old nematodes and the treatments led to a lower expression in young and old animals. Redox biology markers were improved by strawberry treatment in young and old animals, but the best results were found for different dosages depending on age. CONCLUSIONS: Romina cultivar presented promising effects concerning tau-related AD and longevity. Romina might be considered from the point of view of a proper regulation of redox biology, but considering that treatment conditions should be adjusted by age.","PeriodicalId":15194,"journal":{"name":"Journal of Berry Research","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49098136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anthocyanins: what do we know until now?","authors":"F. Giampieri, Danila Cianciosi, J. M. Álvarez-Suarez, J. Quiles, T. Forbes-Hernández, M. Navarro-Hortal, Michele Machì, Michele Ramón del Jesús Palí Casanova, Julio César Martínez Espinosa, Xiu-tian Chen, Di Zhang, Weibin Bai, Tian Lingmin, B. Mezzetti, M. Battino, Yasmany Armas Diaz","doi":"10.3233/jbr-220087","DOIUrl":"https://doi.org/10.3233/jbr-220087","url":null,"abstract":"Diets enriched in plant-based foods are associated with the maintenance of a good well-being and with the prevention of many non-communicable diseases. The health effects of fruits and vegetables consumption are mainly due to the presence of micronutrients, including vitamins and minerals, and polyphenols, plant secondary metabolites. One of the most important classes of phenolic compounds are anthocyanins, that confer the typical purple-red color to many foods, such as berries, peaches, plums, red onions, purple corn, eggplants, as well as purple carrots, sweet potatoes and red cabbages, among others. This commentary aims to briefly highlight the progress made by science in the last years, focusing on some unexpected aspects related with anthocyanins, such as their bioavailability, their health effects and their relationship with gut microbiota.","PeriodicalId":15194,"journal":{"name":"Journal of Berry Research","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48459160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An analysis of hormones and mineral nutrients in fruit from terminal and lateral racemes of two blueberry cultivars","authors":"Min Shen, Qiang Chen, Yan Zhang, Peipei Guo, Bo Zhu, Feng He, Yong Hu, Jiaxin Xiao","doi":"10.3233/jbr-220073","DOIUrl":"https://doi.org/10.3233/jbr-220073","url":null,"abstract":"BACKGROUND: In general, fruit that develops from early-opening flowers ripens earlier than fruit from late-opening flowers. However, the opposite has been observed in the rabbiteye blueberry cultivar “Brightwell” (Vaccinium ashei). OBJECTIVE: From the differences of endogenous hormones and mineral nutrition, with attempt to analyze the reasons for fruit from late-opening flowers on lateral racemes of “Brightwell” ripened earlier than fruit from early-opening flowers on terminal racemes. RESULTS: Fruit from late-opening flowers on lateral racemes of “Brightwell” ripened earlier than fruit from early-opening flowers on terminal racemes. This may be associated with the higher levels of giberellin 1, abscisic acid (ABA), salicylic acid, jasmonic acid, phosphorus, iron and boron in the early developmental stages, and the higher ABA level and lower giberellin 9 level in the fruit ripening stages on lateral racemes, compared with on terminal racemes. However, the fruit borne on the terminal racemes of “O’Neal” grew faster than fruit borne on lateral racemes, this may be correlated with the higher IAA, iron, mangnese, zinc and boron levels, and the lower ABA level, in the early fruit developmental stages on terminal racemes, compared with on lateral racemes. CONCLUSIONS: The growth and ripening differences in fruit set at the two positions of the two blueberry cultivars may be associated with hormonal and nutritional control during fruit development.","PeriodicalId":15194,"journal":{"name":"Journal of Berry Research","volume":"1 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41877456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of different drying temperatures on flavor related quality of blueberry","authors":"Liang Kexin, Li Wanguang, Zhang Yi, Cheng Jiajia, Wang Jun, Y. Liuqing, Wang Chuyan","doi":"10.3233/jbr-220071","DOIUrl":"https://doi.org/10.3233/jbr-220071","url":null,"abstract":"BACKGROUND: Blueberries are rich in organic and inorganic compounds, such as sugars, proteins, polyphenols. But this fruit is highly perishable and difficult to store and transport. Currently, to increase their shelf life, blueberries are often processed into a variety of products. For example, drying is the most frequently processing method. However, the effect of the drying process on flavor and quality remains unexplored. OBJECTIVE: In this study, blueberries were hot air dried at 50, 60, 70, and 80°C. The effect of different drying temperatures on blueberries’ flavor substances and quality, including moisture content, color, reducing sugar, and free amino acids, were investigated. RESULTS: The results demonstrated a significant reduction in the moisture, reducing sugar, and free amino acid contents in dried blueberry products with the drying temperature(P <  0.05). In addition, 50°C significantly promoted the formation of free amino acids, linalool and, α-terpineol crucial flavor components present in blueberries (P <  0.05). Furthermore, minimum thermal damage was observed. In the flavor principal component analysis, the blueberry samples dried at 50°C were the closest to the raw material among all the temperatures tested. Therefore, 50 °C was more suitable for blueberries hot air drying and maintaining the high-quality. CONCLUSION: Overall, this study could explore the influence of different temperatures on the quality of blueberry-dried products and could help optimize the future production and industrialization of blueberries.","PeriodicalId":15194,"journal":{"name":"Journal of Berry Research","volume":"1 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2022-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70019906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A supernatural multipurpose plant sea buckthorn (Hippophae rhamnoides L.): An updated overview of its folk traditional uses, phytochemical profile and biological activities","authors":"A. Hussain, Syed Hussain Imam Abidi, Q. Syed, A. Saeed, Alim-un-Nisa, Naina Naib, Afshan Bano, Sunaina, Mishal Malik, Abad Ali Nadeem","doi":"10.3233/jbr-220055","DOIUrl":"https://doi.org/10.3233/jbr-220055","url":null,"abstract":"BACKGROUND: Sea buckthorn (SBT) (Hippophae rhamnoides L.), a shrub rich with a huge variety of vitamins, antioxidants and other biologically active constituents with pharmacological and cosmaceutical applications. OBJECTIVE: The current review aims to compile the recent reported data on the ethnobotany, phytochemistry, biological activities and cosmaceutical uses of SBT plant from different regions of the world. METHODS: A wide-ranging inquiry on SBT was done electronically on the basis of articles and abstracts published in peer-reviewed journals, issued in conference proceedings, government reports, books, Master’s and Ph.D. theses etc. The research was carried out in different International scientific databases like Academic Search, Biological Abstracts, BIOSIS, BioOne Previews, CabDirect, Cochrane Library, Pubmed/Medline, GeoRef, Google Scholar, JSTOR, Journal Citation Reports, Mendeley, Publons, Researchgate, Scopus, SciELO, Springer Link, Science Direct, Web of Science, Taylor and Francis with particular keywords. RESULTS: A total of 185 published papers were assessed through the search approach and 162 papers were included published on SBT. It was evident from the literature search that the uses of SBT as traditional medicine so far against nearly 50 health related complications in more than 18 regions of the world are still a common practice where the decoction of leaves and juice/paste from berries/fruits of SBT were the common administration modes. Data on the phytochemical profile of SBT revealed more than 50 diverse reported groups of compounds with remarkable antioxidant activity against reactive oxygen species (ROS) using DPPH, FRAP and ABTS as common methods. Moreover to-date, the reported antimicrobial activity of SBT uncovered that the extracts from SBT were examined in contradiction of 32 strains of bacteria and 15 strains of fungus with significant inhibitory actions against the bacterial and fungal strains. The SBT extracts actions reported so far on different viral disease categories displayed active inhibition of the growth of nearly 15 different viral strains. The reported anticancer activity of compounds in SBT extracts to date evidenced remarkable results against more than 20 different cancer cell lines/ types. Moreover, SBT oil containing fatty acids, tocopherols and carotenoids is effectively used with cosmetics applications for skin care. CONCLUSIONS: Conclusively, SBT is rich with several remarkable phytochemicals that may have diverse biological actions and for that reason reassure the use of decoctions and/or infusions of SBT as folk traditional medicine around the world. Conversely, it is essential to explore the molecular mechanisms of compounds responsible for biological activites of SBT and to advance in the research of clinical uses and development of SBT based therapeutic and cosmetic products.","PeriodicalId":15194,"journal":{"name":"Journal of Berry Research","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44902476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the impact of black chokeberry polyphenols in different matrices on the human gut microbiota using the in vitro model of the large intestine (TIM-2)","authors":"G. Catalkaya, E. Çapanoğlu, K. Venema","doi":"10.3233/jbr-220076","DOIUrl":"https://doi.org/10.3233/jbr-220076","url":null,"abstract":"BACKGROUND: Despite the great range of health-beneficial activities associated with dietary polyphenols, their influence on gut ecology remains poorly understood. Only a few studies have examined the impact of black chokeberry polyphenols present in different matrices on human gut microbiota, and in fact none have examined encapsulated black chokeberry polyphenols. OBJECTIVE: The objective of this study was to evaluate the effect of black chokeberry polyphenols in pulp, extract and encapsulate (in a maltodextrin:gum Arabic polymer system) on human gut microbiota and fecal short-chain and branched-chain fatty acids (SCFA and BCFA, respectively). METHODS: The effect of black chokeberry polyphenols on gut microbiota was tested in a validated, dynamic in vitro model of the colon (TIM-2) for 24 h by applying five different interventions (Pulp, Extract, Encapsulate, Encapsulate control, SIEM) to the standardized microbiota from five healthy donors. RESULTS: We observed that the fermentation of black chokeberry polyphenols in the in vitro colon model (TIM-2) resulted in shifts in the standardized microbiota and differentiation in the extent of the production of SCFA and BCFAs. Synergy between maltodextrin+gum Arabic+polyphenols resulted in an increase in the relative abundances of some health-promoting taxa and decrease in the disease related taxa Alistipes. Encapsulation increased the SCFA production and decreased the BCFA production in the lumen. CONCLUSIONS: Although encapsulation of polyphenols may provide a robust way for their protection, their effect on the gut microbiota should be further investigated both by using different coating materials and with in vivo studies.","PeriodicalId":15194,"journal":{"name":"Journal of Berry Research","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47042816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}