Journal of Biomedical and Pharmaceutical Research最新文献_第2页

Postoperative Recovery and Rehabilitation: A Comparative Analysis of Mobility and Social Dependency After Gamma Nail Vs. Proximal Femoral Nail Surgery 术后恢复与康复：伽马钉与股骨近端钉手术后活动能力和社会依赖性的比较分析股骨近端钉手术后的活动能力和社会依赖性比较分析

Journal of Biomedical and Pharmaceutical Research Pub Date : 2024-04-08 DOI: 10.32553/jbpr.v13i2.1077

Akshay Sharma, Ashish Meena, Anu Kumar Changkum, Lokesh Thakur

{"title":"Postoperative Recovery and Rehabilitation: A Comparative Analysis of Mobility and Social Dependency After Gamma Nail Vs. Proximal Femoral Nail Surgery","authors":"Akshay Sharma, Ashish Meena, Anu Kumar Changkum, Lokesh Thakur","doi":"10.32553/jbpr.v13i2.1077","DOIUrl":"https://doi.org/10.32553/jbpr.v13i2.1077","url":null,"abstract":"Background: The management of stable extracapsular fractures of the proximal femur challenges orthopedic practice, with postoperative recovery and rehabilitation outcomes being crucial for patient independence and quality of life. This study compares Gamma Nail and Proximal Femoral Nail (PFN) regarding mobility and social dependency post-surgery. \u0000Methods: Fifty patients were retrospectively analyzed, divided into two groups based on the surgical intervention received. Mobility scores, social dependency scales, and pain levels were assessed at various postoperative intervals. \u0000Results: The PFN group showed quicker improvements in mobility and reductions in social dependency, with notably less pain reported in the early postoperative period. Both interventions were effective, but PFN presented some advantages in facilitating rehabilitation. \u0000Conclusion: While both Gamma Nail and PFN effectively manage stable extracapsular fractures, PFN may offer benefits in early postoperative recovery. Tailoring surgical choices to individual patient needs is essential for optimizing rehabilitation outcomes. \u0000Keywords: Proximal femur fractures, Gamma Nail, Proximal Femoral Nail, postoperative recovery, mobility, social dependency.","PeriodicalId":15193,"journal":{"name":"Journal of Biomedical and Pharmaceutical Research","volume":"170 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140730954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Patient Demographics and Injury Patterns on the Choice and Success of Proximal Femur Fracture Surgeries 患者人口统计学特征和受伤模式对股骨近端骨折手术的选择和成功率的影响

Journal of Biomedical and Pharmaceutical Research Pub Date : 2024-04-08 DOI: 10.32553/jbpr.v13i2.1075

Akshay Sharma, Ashish Meena, Anu Kumar Changkum, Lokesh Thakur

{"title":"Impact of Patient Demographics and Injury Patterns on the Choice and Success of Proximal Femur Fracture Surgeries","authors":"Akshay Sharma, Ashish Meena, Anu Kumar Changkum, Lokesh Thakur","doi":"10.32553/jbpr.v13i2.1075","DOIUrl":"https://doi.org/10.32553/jbpr.v13i2.1075","url":null,"abstract":"Background: Understanding the influence of patient demographics and injury patterns on the choice and success of surgical interventions for stable extracapsular fractures of the proximal femur is crucial for optimizing treatment outcomes. \u0000Methods: This comparative study analyzed 50 patients undergoing CRIF with either Gamma Nail or PFN, focusing on how demographics, injury patterns, and socio-economic status impacted surgical choice and outcomes. \u0000Results: No significant differences were observed in age and socio-economic status between the two groups. Gender distribution and the mode of injury showed slight variations but did not substantially influence the surgical choice. Both Gamma Nail and PFN were utilized across a diverse patient population, suggesting the need for individualized surgical planning. \u0000Conclusion: The choice of surgical technique for treating stable extracapsular fractures of the proximal femur is multifaceted, influenced by a combination of technical, demographic, and injury-related factors. \u0000Keywords: Extracapsular fractures, proximal femur, Gamma Nail, Proximal Femoral Nail, patient demographics, injury patterns.","PeriodicalId":15193,"journal":{"name":"Journal of Biomedical and Pharmaceutical Research","volume":"93 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140728774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Demographic Influence on Percutaneous Tenotomy Outcomes in Chronic Lateral Epicondylitis 人口统计学对慢性外上髁炎经皮腱鞘切开术结果的影响

Journal of Biomedical and Pharmaceutical Research Pub Date : 2024-04-08 DOI: 10.32553/jbpr.v13i2.1076

Anu Kumar Changkum, Ashish Meena, Akshay Sharma, Vipin Sharma

{"title":"Demographic Influence on Percutaneous Tenotomy Outcomes in Chronic Lateral Epicondylitis","authors":"Anu Kumar Changkum, Ashish Meena, Akshay Sharma, Vipin Sharma","doi":"10.32553/jbpr.v13i2.1076","DOIUrl":"https://doi.org/10.32553/jbpr.v13i2.1076","url":null,"abstract":"Background: Chronic lateral epicondylitis, or tennis elbow, affects individuals irrespective of age, gender, or occupation, impacting their functional arm movement and quality of life. Percutaneous tenotomy presents a minimally invasive treatment option, yet its efficacy across different demographic groups remains underexplored. \u0000Methods: This retrospective study at the Department of Orthopaedics, Dr. RPGMC Kangra at Tanda, included 45 patients undergoing percutaneous tenotomy for chronic lateral epicondylitis. Patients were assessed pre-operatively and at intervals up to 36 months post-operation using NRS, DASH, and Oxford scores. \u0000Results: Significant improvements in pain and functional scores were observed across all demographic groups, with no single demographic factor significantly influencing treatment outcomes. \u0000Conclusion: Percutaneous tenotomy is universally effective in treating chronic lateral epicondylitis, offering significant pain relief and functional recovery across diverse demographic groups. \u0000Keywords: Chronic lateral epicondylitis, Percutaneous tenotomy, Demographic influence, Pain relief, Functional recovery..","PeriodicalId":15193,"journal":{"name":"Journal of Biomedical and Pharmaceutical Research","volume":"40 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140728026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Therapy to Treat Various Types of Cancer: An Overview 治疗各种癌症的最新疗法：概述

Journal of Biomedical and Pharmaceutical Research Pub Date : 2024-04-01 DOI: 10.32553/jbpr.v13i1.1064

Amit Kumar, Rajesh Kumar, Ajeet Pal Singh, A. Singh

引用次数: 0

Animal Model of Depression and Anxiety- PROS and CONS 抑郁和焦虑的动物模型--利与弊

Journal of Biomedical and Pharmaceutical Research Pub Date : 2024-03-28 DOI: 10.32553/jbpr.v13i1.1060

Ravinder Kaur, Ritu Rani, A. Singh, A. Singh

引用次数: 0

Tooth Saving Solutions- Best Transport Media for Avulsed Tooth? A Review 救牙方案--脱落牙齿的最佳运输介质？回顾

Journal of Biomedical and Pharmaceutical Research Pub Date : 2024-03-28 DOI: 10.32553/jbpr.v13i1.1063

L. K. Prasada, P. C., Ramya M K

引用次数: 0

Review on the Therapeutic Role of Asclepias tuberosa Seeds in Diabetes Management 关于 Asclepias tuberosa 种子在糖尿病治疗中的治疗作用的综述

Journal of Biomedical and Pharmaceutical Research Pub Date : 2024-03-21 DOI: 10.32553/jbpr.v13i1.1069

Shivangi Shukla, Prashant Singh, R. Shukla

{"title":"Review on the Therapeutic Role of Asclepias tuberosa Seeds in Diabetes Management","authors":"Shivangi Shukla, Prashant Singh, R. Shukla","doi":"10.32553/jbpr.v13i1.1069","DOIUrl":"https://doi.org/10.32553/jbpr.v13i1.1069","url":null,"abstract":"Diabetes mellitus (DM) presents a significant global health challenge characterized by elevated blood glucose levels, leading to debilitating complications. Despite various therapeutic approaches, effective glucose regulation remains elusive, often accompanied by adverse effects from current medications. Medicinal plants, including Asclepias tuberosa, have shown promise in managing blood glucose levels with fewer side effects. This review highlights the potential of Asclepias tuberosa as herbal antidiabetic agents based on recent literature, suggesting avenues for further research and therapeutic development in DM management. Considering the urgent need for safer and more effective antidiabetic treatments, exploring the therapeutic potential of Asclepias tuberosa presents a promising avenue for addressing this growing public health concern. Future studies should focus on elucidating the mechanisms of action, conducting clinical trials to validate the efficacy and safety of Centaurea-based interventions in DM management, and exploring synergistic effects with existing therapies. \u0000Furthermore, within the context of utilizing plant materials for the treatment of Diabetes mellitus, particular attention is directed towards the utilization of Asclepias tuberosa seeds. Asclepias tuberosa, commonly known as butterfly weed or pleurisy root, is a medicinal plant native to North America. Traditionally, various parts of this plant, including the roots, leaves, and seeds, have been used in folk medicine for their purported therapeutic effects \u0000Keywords: Diabetes mellitus, Asclepias tuberosa, antidiabetic agents, herbal remedies, blood glucose regulation.","PeriodicalId":15193,"journal":{"name":"Journal of Biomedical and Pharmaceutical Research","volume":"55 s189","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140223393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutraceuticals for Arthritis Management: Beyond Nutrition, Targeting Inflammation, and Immunity 治疗关节炎的营养保健品：超越营养、针对炎症和免疫力

Journal of Biomedical and Pharmaceutical Research Pub Date : 2024-03-18 DOI: 10.32553/jbpr.v13i1.1066

Kritika, N. Maurya

{"title":"Nutraceuticals for Arthritis Management: Beyond Nutrition, Targeting Inflammation, and Immunity","authors":"Kritika, N. Maurya","doi":"10.32553/jbpr.v13i1.1066","DOIUrl":"https://doi.org/10.32553/jbpr.v13i1.1066","url":null,"abstract":"Nutraceuticals, bridging the gap between \"food\" and \"pharmaceuticals,\" are gaining significant traction in modern healthcare due to their potential to address chronic diseases like arthritis. This shift towards preventative and holistic approaches emphasizes the power of nutrition in managing health. Nutraceuticals encompass a diverse range of bioactive compounds derived from natural sources – vitamins, minerals, plant extracts, proteins, and dietary supplements. Their appeal lies in their purported ability to offer health benefits beyond basic nutrition, including antioxidant, anti-inflammatory, and immunomodulatory properties. Rheumatoid arthritis (RA) presents a significant health concern in India, affecting an estimated 0.75% of adults – exceeding the global average of 0.46%. This prevalence might be linked to genetic similarities between North Indians and Caucasians. Notably, RA affects women more disproportionately. This review explores the potential of nutraceuticals in managing arthritis in India, focusing on their ability to combat inflammation and modulate the immune system, offering benefits beyond simple dietary intervention. \u0000Keywords: nutraceuticals, arthritis management, nutrition, targeting inflammation, immunity.","PeriodicalId":15193,"journal":{"name":"Journal of Biomedical and Pharmaceutical Research","volume":"83 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140232277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Composition and Antioxidant Potential of Cordia macleodii 评估堇菜的成分和抗氧化潜力

Journal of Biomedical and Pharmaceutical Research Pub Date : 2024-02-15 DOI: 10.32553/jbpr.v13i1.1046

Sangeeta Adile, Rohit Seth

{"title":"Evaluation of Composition and Antioxidant Potential of Cordia macleodii","authors":"Sangeeta Adile, Rohit Seth","doi":"10.32553/jbpr.v13i1.1046","DOIUrl":"https://doi.org/10.32553/jbpr.v13i1.1046","url":null,"abstract":"Cordia macleodii is one of the widely used traditional medicinal herbs. The current work was undertaken to systematically extract bioactive components from the fresh plant parts and evaluate their antioxidant potential. Using ethanol as the solvent, volatile chemical components were extracted from the plant material by Soxhlet extraction. Subsequently, GC-HR-MS and FTIR analysis were used to further evaluate the extract. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay and 2,2'- Azinobis [3-ethylbenzothiazoline-6-sulfonic acid (ABTS)] were used to evaluate the antioxidant potentialof the extract in vitro. Quantification of total flavonoid content (TFC) and total phenolic content (TPC) was done against standard solutions of quercetin and gallic acid, which were used in the study as positive controls. The GC-HR-MS analysis reveals two bioactive compounds [(1H)- pyrrol-3-propanoic acid,2 ethoxy carbonyl-4-ethoxy carbonyl methyl]-5,5’-methylene, bis-diethyl ester and Spino [9,9’] difluorene,2,2’-[2,5,8,11-tetraoxado decane-1,12-diye). The FTIR spectrum showed that there were several different functional groups present. Findings of in vitroantioxidant tests revealed that the leaves had the highest total phenolic content (402.19 ± 0.025 mg GAE/g), the highest total phenolic content (93.59 ± 0.01), and the highest ABTS (102.59 ± 0.001) of any plant. To fully evaluate this plant's therapeutic potential, more pharmacognostic research is required. \u0000Keywords: GC-HR-MS, FTIR, TPC, TFC, Antioxidant","PeriodicalId":15193,"journal":{"name":"Journal of Biomedical and Pharmaceutical Research","volume":"251 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139835917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Composition and Antioxidant Potential of Cordia macleodii 评估堇菜的成分和抗氧化潜力

Journal of Biomedical and Pharmaceutical Research Pub Date : 2024-02-15 DOI: 10.32553/jbpr.v13i1.1046

Sangeeta Adile, Rohit Seth

{"title":"Evaluation of Composition and Antioxidant Potential of Cordia macleodii","authors":"Sangeeta Adile, Rohit Seth","doi":"10.32553/jbpr.v13i1.1046","DOIUrl":"https://doi.org/10.32553/jbpr.v13i1.1046","url":null,"abstract":"Cordia macleodii is one of the widely used traditional medicinal herbs. The current work was undertaken to systematically extract bioactive components from the fresh plant parts and evaluate their antioxidant potential. Using ethanol as the solvent, volatile chemical components were extracted from the plant material by Soxhlet extraction. Subsequently, GC-HR-MS and FTIR analysis were used to further evaluate the extract. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay and 2,2'- Azinobis [3-ethylbenzothiazoline-6-sulfonic acid (ABTS)] were used to evaluate the antioxidant potentialof the extract in vitro. Quantification of total flavonoid content (TFC) and total phenolic content (TPC) was done against standard solutions of quercetin and gallic acid, which were used in the study as positive controls. The GC-HR-MS analysis reveals two bioactive compounds [(1H)- pyrrol-3-propanoic acid,2 ethoxy carbonyl-4-ethoxy carbonyl methyl]-5,5’-methylene, bis-diethyl ester and Spino [9,9’] difluorene,2,2’-[2,5,8,11-tetraoxado decane-1,12-diye). The FTIR spectrum showed that there were several different functional groups present. Findings of in vitroantioxidant tests revealed that the leaves had the highest total phenolic content (402.19 ± 0.025 mg GAE/g), the highest total phenolic content (93.59 ± 0.01), and the highest ABTS (102.59 ± 0.001) of any plant. To fully evaluate this plant's therapeutic potential, more pharmacognostic research is required. \u0000Keywords: GC-HR-MS, FTIR, TPC, TFC, Antioxidant","PeriodicalId":15193,"journal":{"name":"Journal of Biomedical and Pharmaceutical Research","volume":"23 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139776456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0