Journal of Applied Solution Chemistry and Modeling最新文献_第9页

Preferential Solvation of Acetaminophen in Propylene Glycol + Water Co-Solvent Mixtures 对乙酰氨基酚在丙二醇+水共溶剂混合物中的优先溶剂化

Journal of Applied Solution Chemistry and Modeling Pub Date : 2014-06-02 DOI: 10.6000/1929-5030.2014.03.02.4

F. Martínez, D. R. Delgado, M. Peña

引用次数: 12

How Multi-Step versus One-Step Preparation Method Affects the Physicochemical Properties and Transfection Efficiency of DNA/DODAB:MO Lipoplexes 多步骤和一步制备方法对DNA/DODAB:MO脂质体理化性质和转染效率的影响

Journal of Applied Solution Chemistry and Modeling Pub Date : 2014-06-02 DOI: 10.6000/1929-5030.2014.03.02.7

M. E. C. R. Oliveira, J. P. Silva, A. C. Oliveira, M. Lúcio, A. Gomes

{"title":"How Multi-Step versus One-Step Preparation Method Affects the Physicochemical Properties and Transfection Efficiency of DNA/DODAB:MO Lipoplexes","authors":"M. E. C. R. Oliveira, J. P. Silva, A. C. Oliveira, M. Lúcio, A. Gomes","doi":"10.6000/1929-5030.2014.03.02.7","DOIUrl":"https://doi.org/10.6000/1929-5030.2014.03.02.7","url":null,"abstract":"The consequences for the transfection efficiencies of different lipoplexes preparation methods, largely remain to be explored, but the knowledge of how different experimental approaches can affect the physicochemical properties and transfection efficiency is essential for a proper tailoring of transfection complexes to particular applications. Therefore, the influence of the number of mixing steps (one-step addition versus multi-step addition of liposomes to plasmid DNA (pDNA)) and lipoplex incubation temperature on the final physicochemical properties and transfection efficiency of pDNA/ Dioctadecyldimethylammonium Bromide (DODAB):1-monooleoyl-rac-glycerol (MO) complexes was studied in three distinct DODAB:MO molar ratios: 4:1, 2:1 and 1:1. Dynamic Light Scattering (DLS), Zeta (I¶) Potential, Ethidium Bromide (EtBr) exclusion assays were used to assess the formation, structure and destabilization of the lipoplexes, whereas in vitro transfection assays with pSV-I²-gal plasmid DNA were performed to evaluate their transfection efficiency on the 293T mammalian cell line. Results indicate that the morphology of pDNA/DODAB:MO complexes is dependent on the lipoplex preparation method, resulting in particles of distinct size, surface charge and membrane fluidity. These variations are visible during the complexation dynamics of pDNA and continue throughout the profile of pDNA release from pDNA/DODAB:MO lipoplexes upon incubation with Heparin (HEP), as well as in the in vitro transfection assays. The stepwise addition of DODAB:MO vesicles to pDNA decreases the transfection efficiency of the lipoplexes, while the effect of the lipoplex preparation methods is dependent on the MO content.","PeriodicalId":15165,"journal":{"name":"Journal of Applied Solution Chemistry and Modeling","volume":"12 1","pages":"94-105"},"PeriodicalIF":0.0,"publicationDate":"2014-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81615518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Effects of Additives upon Percolation Temperature in AOT-Based Microemulsions 添加剂对aot微乳中渗透温度的影响

Journal of Applied Solution Chemistry and Modeling Pub Date : 2014-06-02 DOI: 10.6000/1929-5030.2014.03.02.8

J. Mejuto, J. Morales, O. Moldes, A. Cid

引用次数: 4

Viscosities of Binary Liquid Mixtures of Acetylene Tetrachloride with Benzene, Toluene, p-xylene, Acetone & Cyclohexane at 303.15K 303.15K时四氯化乙炔与苯、甲苯、对二甲苯、丙酮和环己烷二元液体混合物的粘度

Journal of Applied Solution Chemistry and Modeling Pub Date : 2014-06-02 DOI: 10.6000/1929-5030.2014.03.02.5

A. Tripathi, M. Agrawal

{"title":"Viscosities of Binary Liquid Mixtures of Acetylene Tetrachloride with Benzene, Toluene, p-xylene, Acetone & Cyclohexane at 303.15K","authors":"A. Tripathi, M. Agrawal","doi":"10.6000/1929-5030.2014.03.02.5","DOIUrl":"https://doi.org/10.6000/1929-5030.2014.03.02.5","url":null,"abstract":"Viscosities which are accurate to ± 0.01mP, have been measured for binary liquid mixtures of acetylene tetrachloride (CHCl 2 CHCl 2 ,hereafter abbreviated simply as ATC) with benzene, toluene, p-xylene, acetone and cyclohexane at 303.15 ±0.01K. The values of the quantity Δη, which refer to the deviations of the experimental values of the dynamic viscosities of the mixtures from the mole fraction mixture law values, have been found to be negative for the systems ATC-benzene, ATC-toluene, ATC-p-xylene and ATC-cyclohexane. For ATC-acetone, ∆η has been found to be negative at low mole fractions of ATC and positive at high mole fractions. Also the values of the parameter d have been calculated from the equation ln η = x 1 ln η 1 +x 2 ln η 2 +x 1 x 2 d, where η 1 & η 2 refer to the dynamic viscosities of the two pure liquids 1 and 2 whose mole fractions in the mixtures are x 1 & x 2 respectively. The values of d indicate the existence of specific interaction of ATC with benzene, toluene, p-xylene and acetone. The viscosity data have been analysed in the light of absolute reaction rate and free volume theories of liquid viscosity.","PeriodicalId":15165,"journal":{"name":"Journal of Applied Solution Chemistry and Modeling","volume":"21 1","pages":"74-80"},"PeriodicalIF":0.0,"publicationDate":"2014-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75199925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thermally Stable Multilamellar Structure of DNA/Cationic Lipid Complex in the Bulk State 体积状态下DNA/阳离子脂质复合物的热稳定多层结构

Journal of Applied Solution Chemistry and Modeling Pub Date : 2014-06-02 DOI: 10.6000/1929-5030.2014.03.02.2

Ching-Mao Wu, Szu-Yin Lin

引用次数: 0

Solubilization of Hydroxypropyl-β-Cyclodextrin on Cholesterol in Aqueous Solution 羟丙基-β-环糊精对胆固醇的增溶作用

Journal of Applied Solution Chemistry and Modeling Pub Date : 2014-05-02 DOI: 10.6000/1929-5030.2014.03.02.1

C. Zou, Lu Zhou, Ya-li Wang, Lu Li

引用次数: 0

Anisotropic Properties of Mesogenic Surfactants with Ionic Liquid Core 具有离子液体核的介生表面活性剂的各向异性

Journal of Applied Solution Chemistry and Modeling Pub Date : 2014-03-17 DOI: 10.6000/1929-5030.2014.03.01.2

S. Ujiie, Jinzhi Wu, Masanori Nata

{"title":"Anisotropic Properties of Mesogenic Surfactants with Ionic Liquid Core","authors":"S. Ujiie, Jinzhi Wu, Masanori Nata","doi":"10.6000/1929-5030.2014.03.01.2","DOIUrl":"https://doi.org/10.6000/1929-5030.2014.03.01.2","url":null,"abstract":"Ionic mesogens ( HI- n ), constructed from imidazolium-functionalized azobenzenes with differential flexible spacers and a nitro polar terminal group, were synthesized. Their potential thermotropic liquid crystal properties were investigated by polarizing optical microscopy (POM), differential scanning calorimetry (DSC) and temperature variable X-ray diffraction measurements. HI- n exhibited a smectic A fluid (SmA) phase by anisotropy through interactions between azobenzene units and ionic interactions. This SmA formation was observed by POM and DSC. In the SmA phase, focal conic fan textures were observed by POM under the crossed-Nicols. The perpendicular structure (homeotropic alignment) formed spontaneously in the SmA phase through physical adsorption of imidazolium ionic units upon a glass plate. In the SmA phase, HI- n exhibited the X-ray diffraction patterns consisting of sharp inner reflections, corresponding to the layer distance, and a broad outer reflection exhibiting a short range order within the smectic layer. It is expected that the SmA layer consists of the hydrophilic and hydrophobic sublayers. The hydrophilic sublayer was formed by an ionic aggregation of imidazolium and iodide ions. On the other hand, the hydrophobic sublayer was obtained by segregation from the hydrophilic sublayer. It can be considered that HI- n are an anisotropic ionic liquid because the SmA state has a fluidity such as an ionic liquid. The ionic material shows the strong temperature dependence of an ionic interaction. The ionic interactions in the liquid crystal phase became weak gradually with increasing temperature, and the fluidity of the liquid crystal phase increase. HI- n dissolved in water. The HI- n water solution revealed a lyotropic smectic A anisotropic fluid.","PeriodicalId":15165,"journal":{"name":"Journal of Applied Solution Chemistry and Modeling","volume":"1 1","pages":"8-14"},"PeriodicalIF":0.0,"publicationDate":"2014-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80729713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Azeotropy Breaking in Refrigerant Blends with Ionic Liquids 与离子液体混合的制冷剂共沸破坏

Journal of Applied Solution Chemistry and Modeling Pub Date : 2014-03-17 DOI: 10.6000/1929-5030.2014.03.01.1

V. Mazur, S. Haddad, D. Nikitin

引用次数: 4

Application of Polyacrylamide for Methylene Blue Removal from Aqueous Solutions 聚丙烯酰胺在水溶液中去除亚甲基蓝中的应用

Journal of Applied Solution Chemistry and Modeling Pub Date : 2014-03-17 DOI: 10.6000/1929-5030.2014.03.01.5

H. Mousavi, A. Khaligh, M. Behzad, J. Rahchamani

引用次数: 4

'Meyer-Neldel Rule': True History of its Development and its Intimate Connection to Classical Thermodynamics “Meyer-Neldel规则”:其发展的真实历史及其与经典热力学的密切联系

Journal of Applied Solution Chemistry and Modeling Pub Date : 2014-03-17 DOI: 10.6000/1929-5030.2014.03.01.3

E. Starikov

引用次数: 15