{"title":"羟丙基-β-环糊精对胆固醇的增溶作用","authors":"C. Zou, Lu Zhou, Ya-li Wang, Lu Li","doi":"10.6000/1929-5030.2014.03.02.1","DOIUrl":null,"url":null,"abstract":"Hydroxypropyl-I²-Cyclodextrin (HP-I²-CD), prepared via reaction of I²-Cyclodextrin (I²-CD) and propylene oxide (PO), is utilized to research solubilization of HP-I²-CD on cholesterol in aqueous solution. HP-I²-CD is characterized by Fourier Transform Infrared Spectrometry (FT-IR), and concentrations of cholesterol solution are measured by ultraviolet and visible (UV VIS) spectrophotometer. The research on optimal synthesis conditions of HP-I²-CD indicates that sodium hydroxide amounts have the most effect on yields of product. The maximum solubilization multiples of HP-I²-CD reaches 15, below which molecular rate of HP-I²-CD and cholesterol in inclusion complex is 1:1.","PeriodicalId":15165,"journal":{"name":"Journal of Applied Solution Chemistry and Modeling","volume":"32 1","pages":"48-52"},"PeriodicalIF":0.0000,"publicationDate":"2014-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Solubilization of Hydroxypropyl-β-Cyclodextrin on Cholesterol in Aqueous Solution\",\"authors\":\"C. Zou, Lu Zhou, Ya-li Wang, Lu Li\",\"doi\":\"10.6000/1929-5030.2014.03.02.1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hydroxypropyl-I²-Cyclodextrin (HP-I²-CD), prepared via reaction of I²-Cyclodextrin (I²-CD) and propylene oxide (PO), is utilized to research solubilization of HP-I²-CD on cholesterol in aqueous solution. HP-I²-CD is characterized by Fourier Transform Infrared Spectrometry (FT-IR), and concentrations of cholesterol solution are measured by ultraviolet and visible (UV VIS) spectrophotometer. The research on optimal synthesis conditions of HP-I²-CD indicates that sodium hydroxide amounts have the most effect on yields of product. The maximum solubilization multiples of HP-I²-CD reaches 15, below which molecular rate of HP-I²-CD and cholesterol in inclusion complex is 1:1.\",\"PeriodicalId\":15165,\"journal\":{\"name\":\"Journal of Applied Solution Chemistry and Modeling\",\"volume\":\"32 1\",\"pages\":\"48-52\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2014-05-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Applied Solution Chemistry and Modeling\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6000/1929-5030.2014.03.02.1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Solution Chemistry and Modeling","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6000/1929-5030.2014.03.02.1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Solubilization of Hydroxypropyl-β-Cyclodextrin on Cholesterol in Aqueous Solution
Hydroxypropyl-I²-Cyclodextrin (HP-I²-CD), prepared via reaction of I²-Cyclodextrin (I²-CD) and propylene oxide (PO), is utilized to research solubilization of HP-I²-CD on cholesterol in aqueous solution. HP-I²-CD is characterized by Fourier Transform Infrared Spectrometry (FT-IR), and concentrations of cholesterol solution are measured by ultraviolet and visible (UV VIS) spectrophotometer. The research on optimal synthesis conditions of HP-I²-CD indicates that sodium hydroxide amounts have the most effect on yields of product. The maximum solubilization multiples of HP-I²-CD reaches 15, below which molecular rate of HP-I²-CD and cholesterol in inclusion complex is 1:1.
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